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SISCOPE: a multiuser information system for gastrointestinal endoscopy.

SISCOPE is an integrated data management system for use in gastrointestinal endoscopy units which operates in the multiuser mode on UNIX minicomputers or MS-DOS personal computers and can be used for patient bookings, endoscopic data entry and retrieval, and automatic report generation in upper gastrointestinal endoscopy, proctologic examinations, colonoscopy and peritoneoscopy. The description of endoscopic findings is remarkably detailed and data entry very rapid due to an advanced design of input screens that incorporates several recent concepts, including windows, menu bars and pull-down menus; typing is eliminated as data is entered with a mouse by pointing at options within menus. Endoscopic findings can be described under eight headings: morphology, topography, qualifiers, modifiers, signs of bleeding, endoscopic diagnosis, pathological diagnosis and etiology. Terminology is based strictly 3on the OMED system. SISCOPE also allows recording of details on endoscopic procedures, indications for the examination, preparation, premedication, complications and late entry of pathology reports. After entering all data, a report in natural language is produced automatically, the entire process taking one minute on average. Data retrieval programs give on-line access to previous examinations of a given patient and automatically generate activity reports. A formal language allows direct queries to the database and transfer of data for statistical analysis or other data processing. The system is simple to learn and use because operation is intuitive and all endoscopic techniques share the same basic menu structure and screen design.

Computer Systems↗

Data base management system for tracking occupational health.

An Occupational Health Information System (OHIS), a data base management system for tracking occupational health, has been developed. A primary feature is its ability to correlate employee workplace environment with health. Hardware implementation of OHIS is on a minicomputer with application programs written in ANSI standard MUMPS language. OHIS integrates personnel, medical and industrial hygiene/toxicology information into one data base. The personnel module is comprised of demographic information collected and updated by the personnel department. The medical module utilizes an interactive video display terminal (VDT)-driven questionnaire and multiphasic testing subsystems which are accessed selectively by authorized users. The backbone of OHIS is a parameter dictionary of all possible data elements. A final medical report includes a medical history summary, physical findings and X-ray interpretation, highlighted and normal test findings, computer interpretations, and a final one-page summary of problem and health-risk information. Information characterizing the workplace environment is captured and reported by the questionnaire subsystem. This questionnaire is designed to define: 1) monitoring conditions, 2) sample analysis, 3) measurement results, and 4) personal protective equipment used. These data provide a means of assigning environmental exposure measurements to appropriate employees.

Adult↗

A clinically operational method for three-dimensional dose calculations.

Three-dimensional dose calculations can now be performed for both photon and neutron beam therapy in reasonable times on a minicomputer. The method described is a scatter-air ratio-tissue-air ratio (SAR-TAR) model which, for any beam, finds the correct depth at each point in a patient even when the beam passes obliquely through more than one transverse section of the patient. Scatter dose is determined by performing a Clarkson integration over both angle and radial distance, with the correct depth of the beam calculated at both accumulation and scatter points. Doses are computed and displayed over a 0.33 cm sampling grid superimposed on each transverse CT slice used in treatment planning. Dose-volume histograms are made for the entire patient volume and for internal organs and target volumes outlined by the physician. The clinical efficacy of the method in therapy planning is demonstrated and a comparison is made between this method and single section two-dimensional methods.

Breast Neoplasms↗

Analysis of biological sequences on small computers.

We review a wide range of programs for micro- and minicomputers that facilitate the collection and analysis of DNA, RNA, or protein sequences. Special-purpose programs that perform a single function and general-purpose programs that perform a set of functions are both considered. The information presented should be useful to any biologist who wishes to obtain a computer program to aid in sequence investigations.

Amino Acid Sequence↗

A comprehensive package for DNA sequence analysis in FORTRAN IV for the PDP-11.

A computer package written in Fortran-IV for the PDP-11 minicomputer is described. The package's novel features are: software for voice-entry of sequence data; a less memory intensive algorithm for optimal sequence alignment; and programs that fit statistical models to nucleic acid and protein sequences.

Base Sequence↗

Some characteristics of sleep spindles derived from automatic analysis.

Sleep spindles in eight normal adults were analyzed automatically by a minicomputer. The accuracy of spindle detection was about 90%. Spindle wave frequency was measured by an approximation method for the spindle peaks; this method employed a quadratic equation on prior analog filtering. The accuracy of measurement was within 0.6 msec (SD 1). The average spindle wave frequency was about 13 Hz, but varied depending on the sleep stage and brain region. The frequency was highly variable and displayed no tendency. Concerning spindle duration, short spindles were followed by either short or long spindles, while long spindles rarely were followed by long ones. As sleep progressed, spindle duration tended to become shorter. There was a tendency for one long interval of spindle appearance not to be followed by another long interval of appearance. However, as sleep progressed, the interval of spindle appearance had a tendency to become prolonged.

Adult↗

A computer system for biomedical equipment maintenance reporting.

Biomedical equipment maintenance and repair activities involve an increasing amount of paperwork and report generation. A computer system is described that collects the necessary data on-line for accuracy and efficiency. The system can generate various reports relating to repair history, spare parts usage and preventive maintenance scheduling. It is implemented on a time-sharing minicomputer, and can reduce substantially the time spent by biomedical engineers in documenting their activities.

Computers↗

The use of rotating gratings for the treatment of amblyopia: a clinical trial.

The use of rotating gratings for the treatment of amblyopia was subjected to a controlled clinical trial. A treatment group (N = 19) observed rotating gratings for 15 min per week for 10 weeks and a control group (N = 19) observed a blank rotating disk for the same period. Both groups of amblyopes performed visually guided tasks to maintain their interest during treatment. Data were acquired in a double-masked manner. A second control group (N = 4) underwent weekly acuity evaluation without any form of treatment. Visual acuity was evaluated before and after each session and analyzed with a linear regression fit to a probit transform by a minicomputer. By using a criterion change in acuity of 10% Snell Sterling, we found no significant change of acuity in any group or between groups. These results demonstrate that rotating gratings are an insignificant variable in the treatment of amblyopia.

Adolescent↗

A computerized TLD system.

A computerized thermoluminescent (TL) readout technique is presented which considerably improves the precision of dose readout and facilitates the dose information management and storage. The technique is relatively simple and it involves an interface between a commercially available thermoluminescent dosimetry (TLD) analyzer and a minicomputer. Curve fitting, subtraction of unwanted thermogram peaks, background subtraction, studies of TL decay kinetics, and storage of large number of measured TL data are easily performed with the technique.

Computers↗

Analytic calculation of electron beam isodose distributions.

Analytical techniques have been developed to generate electron beam isodose distributions from a modest set of experimental data. These techniques include (1) development of a compact yet powerful linear least-squares optimization program with a graphic display of the results, (2) coordinate transformations to allow straightforward fitting of the isodose distributions with simple polynomial functions, and (3) accurate interpolation methods to allow production of treatment planning dose matrices. The program, written in FORTRAN, has been implemented on a minicomputer and uses the standard peripherals of a commercially available treatment planning system (AECL TP-11). The computer-generated isodose and central-axis distributions correspond very closely with the data for electron energies from 5 to 20 MeV and for all field sizes.

Electrons↗

Vrx: a verify-record system for radiotherapy.

A system of computer programs has been created to allow the entry of radiotherapy treatment details as defined by the physician, the verification of the machine parameters at every treatment, and the recording of the entire course of treatment. Various utility programs are available to simplify the use and maintenance of the system. The majority of the code is written in FORTRAN-77, the remainder in MACRO-11. The system has been implemented on a PDP 11/60 minicomputer for use with a Mevatron linear accelerator, the implementation required minor hardware changes to the accelerator.

Computers↗

A speech-to-noise ratio measurement algorithm.

An algorithm to measure speech-to-noise ratios has been implemented on a minicomputer. The algorithm attributes the energy within each consecutive 20-ms frame of a speech-plus-noise waveform to either a speech or noise source. This discrimination process is based upon the known characteristics of frame energy histograms of such waveforms. In response to observed inaccuracies of this discrimination process in cases of low speech versus noise separation, a method of estimating the speech Vrms of the signal is incorporated which attempts to recover speech energy, "masked" by noise. The algorithm's ability to track known speech-to-noise ratios on a decibel-for-decibel basis down to a ratio of approximately 5 dB has been demonstrated by experimentation.

Minicomputers↗

Computerised nutritional data management in neonatal intensive care.

We report a minicomputer based recording, reporting, and research system for patient data management in the neonatal intensive care unit (NICU). It is moderately priced, transportable, and independent of a central computer. It requires only a desk top and standard power supply, and successfully meets the medical documentation, communication, and research needs of the NICU. The first phase of programme development has enabled us to process growth and nutritional data from infants on complex parenteral and enteral nutrition. The system is well suited to medical users and provides a practical interactive data management system with many potential applications in the NICU.

Australia↗

Microfiche as a medium for the long-term storage of laboratory computer records.

The chemical pathology requests on 180 000 patients a year are stored on microfiche, occupying 72 mm of shelf space. They are produced by a sequence of three computer programs which remove data from disc on to magnetic tape using the laboratory's Digital Equipment Corporation PDP 11/34 minicomputer. Processing on to microfiche is performed by a bureau. The magnetic tape is available for retrospective research and management studies in one-month periods.

Chemistry, Clinical↗

A computer system for transcribing radiology reports.

A minicomputer system has been developed to assist in the transcription, distribution, and long-term storage of radiology reports. Reports are dictated in the traditional manner by a radiologist and then entered into specially programmed computer terminals by a transcriptionist. Completed reports are electronically distributed throughout the department and the hospital. Inactive reports are stored by the computer on microfiche. At one institution, the system is used to produce all of the reports in the radiology department, a total of approximately 200,000 reports per year.

Computers↗

Operational radiologic image archive on digital optical disks.

A digital optical disk archive for storage of computed radiographic, computed tomographic, magnetic resonance, ultrasonographic, and digitized film radiographic images was installed. In the system, digital images enter a minicomputer, are temporarily stored on magnetic disks, and are archived onto write-once read-many optical disks at their full resolution. A pictorial index of minified images is maintained for each patient. After 8 months of operation, 49,400 megabytes of images had been retained on 19 optical disks stored, after January 1987, in a mechanical jukebox-style optical disk library. The success rate for archival capture of images during the initial period was 96.6%. The failures were due to overfilling of the magnetic disk, a problem addressed through the addition of a second magnetic disk unit. There were no medium-related image errors during the early period. Problems resulting from the slow speed of optical disk systems were addressed operationally by initiating recall of a patient's archived images from the optical to the faster magnetic disk as soon as the system received a request to acquire a new image. Also, optical disk retrieval times are expected to improve with technologic development.

Electronic Data Processing↗

Stereotactic surgical planning with magnetic resonance imaging, digital subtraction angiography and computed tomography.

Over the past 2 years at the Montreal Neurological Institute and Hospital, we have evolved an integrated environment for the planning of stereotactic procedures, based on images from magnetic resonance imaging, digital subtraction angiography and computed tomography modalities. These procedures rely on fiducial marker sets which are attached to our 'OBT' stereotactic frame, and which may be recognized in the images. The software package is modular and operates in both minicomputer (PDP-11 and VAX) and IBM personal computer environments. In addition to routine tasks for stereotactic planning, the package also supports dosimetry planning for stereotactic radiosurgery.

Brain↗

A computerised EEG-analyzing system for small laboratory animals.

The experimental setup, including instrumentation and software packaging, is described for the use of a minicomputer as an on-line analyzing system of the EEG in rats. Complete fast Fourier transformation of the EEG sampled in 15 episodes of 10 s each is plotted out within 7 min after the start of registration of the EEG signal. The influence of high voltage spikes, spindles and baseline drift on the power density spectrum is shown and a method of clipping is presented that excludes these kinds of artefacts. The normalized standard error of the power density estimate is determined by the smoothing procedure and is at maximum 26%.

Animals↗