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Study on pottical type, palmar and plantar digital formulae, hand clasping, arm folding, handedness, leg folding and stride type in the Daur population, China.

The pottical type, palmar and plantar digital formulae, hand clasping, arm folding, handedness, leg folding and stride type have been investigated on a sample of 143 male and 160 female students of the Daur population of Molidawa Banner, Inner Mongolia. The results of this study are the following: 1. the frequency of the hyperextensive pottical type is 49.17%, the relative length of index over annularis 12.21%, right hand clasping 45.87%, right arm folding 49.50%, right handedness 94.39%, right leg folding 72.28% and right stride type 44.88%, 2. pottical type, hand clasping, handedness, leg folding and stride type do not show significant sex differences, 3. there are some relations between hand clasping and arm folding as well as between arm folding and stride type, 4. compared with other population groups, the Daur population shows a low frequency of right hand clasping, a moderate frequency of right arm folding and a low frequency of left handedness.

Adolescent↗

Handedness and footedness in Korean college students.

This study was conducted to obtain normative data on foot preference and to compare footedness and handedness in a large sample (N = 866) of college students in Korea, where left-hand use for writing and other public acts is severely restricted (Kang & Harris, 1993). Based on scores from Korean-language versions of the Edinburgh Handedness Inventory (EHI; Oldfield, 1971) and the Waterloo Footedness Questionnaire Revised (WFQ-R; Elias, Bryden, & Bulman-Fleming, 1988), 11% of the subjects were left-footed but only 4.2% as left-handed. A significantly higher percentage of left-handers than right-handers showed crossed lateral preference, that is, for preference of the opposite-side foot. Of the left-handers with crossed preference, the majority were inconsistent left-handers (ILH; Peters & Servos, 1989), whereas most of those with uncrossed preference were consistent left-handers (CLH). Factor analysis of the EHI and WFQ-R revealed 2 handedness factors and 2 footedness factors. The footedness factors for skilled unipedal actions and for balancing-stabilizing varied in direction, strength, and relation to handedness in mixed-footers and left-handers, consistent with the possibility that the division of footedness into these categories might be neuropsychologically meaningful.

Adult↗

Handedness effects on transient evoked otoacoustic emissions in schoolchildren.

Handedness, as a potentially influencing, nonpathologic factor, has not been investigated in relation to transient evoked otoacoustic emissions (TEOAEs). The present study aimed to examine the effects of handedness on the TEOAE spectrum in entry-level schoolchildren, with attention also to possible ear asymmetry. A total of 228 subjects (114 males, 114 females, mean age = 6.3 years) were tested using the ILO292 Otodynamics Analyzer (Quickscreen mode) in quiet rooms in 22 schools. For statistical analysis, subjects were matched for factors such as handedness, gender, age, and history of recent ear infection. The results from subjects with passing TEOAE, pure-tone screening, and tympanometry revealed no significant handedness effect overall, although a significant ear asymmetry effect on the measurement parameters of AB difference, noise level, response level, whole-wave reproducibility, band reproducibility, and signal-to-noise ratios was found.

Acoustic Stimulation↗

[Reliability and validity of a handedness questionnaire].

OBJECTIVE: In this study, the validity and reliability of the hand preference item of a 13-item questionnaire adapted from Chapman and Chapman (1987) were investigated. METHOD: This questionnaire requires subjects to indicate which hand they usually use for various actions as follows: writing, drawing, throwing, using a hammer, using a toothbrush, using an eraser on paper, using scissors, holding a match when striking it, stirring a can of paint, using a spoon, using a screwdriver, twisting off the lid of a jar, and using a knife. Each item was scored as "1" for right, "2" for either, or "3" for left, and the handedness of subjects was scored from 13 (the strongest right-hand preference) to 39 (the strongest left-hand preference). In this study, 449 subjects filled in the questionnaire, and 43 subjects attended the test-retest study 3 weeks after the first examination. In order to determine the validity of the questionnaire, fine motor performance was measured using a finger tapping task, and the eye and foot preferences of the subjects were evaluated. RESULTS: The test-retest reliability (r=.993) and internal consistency (Cronbach's Alpha=.97) were found to be high. In item-total score analysis, the best single item was "using a hammer", while the worst item was "twisting off the lid of a jar". Factor analysis yielded two factors, skilled and unskilled activities. Handedness scores were found to show a significant correlation with foot preference scores and the dominance score of the finger tapping task. CONCLUSION: The results suggest that the handedness questionnaire is reliable and valid in measuring handedness.

English Abstract↗

Handedness and spinal deformity.

Biological lateralisation is clearly manifest in scoliosis, yet its relevance is unclear. Goldberg et al. (Spine. 15(2):61-64. 1990) found an association between curve pattern and hand-preference in a screened population, but no increase in sinistrality. Milenkovic et al, (European Journal of Epidemiology, 19:969-972,2004) concluded left-handedness was a risk factor in a screened group. The database was reassessed to determine whether clinically significant scoliosis was associated with sinistrality or differed from the population norm of 10%. Patients attending the scoliosis clinic were asked their preferred writing hand. 1,636 patients were identified with complete data. Overall, left handedness occurred in 11.5%, greater than the general population (p=0.04) Left hand preference was found to be increased in boys with infantile idiopathic scoliosis and in girls with infantile, juvenile, congenital and syndromic scoliosis, but was reduced in girls with adolescent idiopathic scoliosis. Scoliosis lateralisation was random in infantile and congenital scoliosis, while left curve patterns were decreased in girls with juvenile idiopathic scoliosis and increased in boys with syndromic scoliosis. Curve pattern and handedness correlated in asymmetry in boys and girls and in girls with radiologically confirmed adolescent idiopathic scoliosis, but not in any other type. This study cannot confirm findings of left-handedness as a risk factor for spinal deformity. Its incidence is reduced in girls with adolescent idiopathic scoliosis, and the increased sinistrality in infantile scoliosis is not a new finding (Rauterberg & Tonnis Ger. Z.Orthop. 109(14):676-689. 1971). Lateralisation is undoubtedly a factor in scoliosis, but does not have a simple causal relationship, probably deriving from the underlying scoliotic process, rather than contributing to it.

Adolescent↗

[The difference between the mineral content and the width of the radius on each side and its significance for handedness determination of skeletal material].

The objective of our work was to investigate whether the side-different use of the upper extremities due to handedness produces detectable differences in bone-mineral content (BMC) and bone width (BW). For this purpose 251 recent individuals whose handedness was established, were examined by means of the 125I-photon-absorption technique. Highly significant right-left differences in BMC and BW were found on the midshaft and distal radius. Discrimination functions based on BMC and BW were carried out, allowing for the classification into the appropriate handedness categories. Applying the same method we tried to diagnose the handedness of the skeletal material of 40 medieval and 27 neolithic individuals.

Absorptiometry, Photon↗

A controlled study of Tourette syndrome. VI. Early development, sleep problems, allergies, and handedness.

Developmental milestones, problems with bladder and bowel control, sleep disturbances, allergies, and handedness were compared in 247 consecutive Tourette syndrome (TS) patients, 17 patients with attention-deficit disorder (ADD), 15 patients with ADD secondary to TS (ADD 2(0) TS), and 47 random controls. There were no significant differences in age of first talking or walking. By contrast, there were significant differences in problems with bladder and bowel control between TS patients and controls, as measured by age of first toilet training, age of last bed-wetting, frequency of enuresis, and age that bowel control was achieved. Sleep problems were pervasive in TS patients, with a significantly increased frequency of sleepwalking, night terrors, trouble getting to sleep, early awakening, and inability to take afternoon naps as a young child. In all diagnostic categories, including mild (grade 1) TS patients, a total sleep-problem score was significantly greater than that in controls. The sleep disorders and other TS symptoms are consistent with TS as a disorder of disinhibition of the limbic system. Allergies and left-handedness have been evoked as contributing to or being associated with ADD and learning disorders. There were no significant differences in the frequency of allergies or left-handedness in TS patients compared with that in controls. We conclude that when there is a clearly defined genetic cause of ADD and learning disorders, it is not associated with an increased frequency of allergies or left-handedness.

Adolescent↗

Differences in divergent thinking as a function of handedness and sex.

The relationship between handedness and divergent thinking was explored in four studies. Experiment 1 (N = 556) used the Alternate Uses Test, Experiment 2 (N = 941) tested object synthesis, and Experiment 3 (N = 965) tested ideational flexibility. No difference as a function of handedness was found in Experiment 1, but in Experiments 2 and 3 divergent thinking was significantly related to handedness in males. Left-handed males had higher divergent thinking scores, and the scores rose systematically with increasing sinistrality. Handedness was not related to divergent thinking ability in females. Experiment 4 (N = 1,548) showed that these differences were not associated with superiority by left-handed individuals in convergent thinking. Interpretations based on altered neurological development due to factors such as fetal testosterone exposure are discussed.

Adolescent↗

Handedness distribution in a nonspeaking population with mental retardation.

Fifty nonspeaking or minimally speaking subjects with moderate, severe, or profound mental retardation underwent evaluation of handedness. Results confirmed previously reported increased prevalence of non-right handedness and the occurrence of a large subtype of ambiguous handedness. Results suggest that incidence of atypical hand preference is not closely linked to level of cognitive impairment, especially as represented by significant speech-language impairment in this population, as has been previously hypothesized. Atypical handedness of persons with mental retardation probably depends on language organization, and there is little support for the view that such subtypes represent bilateral hemispheric damage.

Adolescent↗

Birth weight and handedness in boys and girls.

The association between selected demographic variables and birth weight on the one hand and a composite hand preference score based on seven hand tasks (each performed twice) on the other was investigated in a sample of 1387 male and female schoolchildren aged 5 to 10 years old. In multiple regression models left-handedness was significantly more common among boys and among children of better educated mothers and tended to decrease with age. No association was found with respect to urban or rural residence or birth order. Increased birth weight was associated with right-handedness in boys but with left-handedness in girls, and the birth weight by sex interaction term was statistically significant (p = 0.037). The demographic associations in the present study are compatible with those reported previously. The different associations of birth weight with hand preference in boys and girls indicate that the prenatal hormonal factors that affect brain lateralization and handedness are qualitatively or quantitatively different in the two sexes and may be differentially associated with birth weight.

Age Factors↗

[Neuropsychology of left-handedness: current knowledge].

About 10% of the population is left-handed or non-right handed. Its brain organization and cognitive skills could differ in relation to right-handed subjects. Our current knowledge is far of get to know its etiology. The scientific literature is sufficiently wide as interesting to review its main contributions. The experimental studies undertake the last 30 years, but this current revision is centred on studies from the last 10 years. From them it is concluded that in Neuropsychology of the left-handedness there are great disagreements. The investigation needs to distinguish types of left-handedness or non-right-handedness, while it is not demonstrated that there is a single type of left-handedness.

Brain↗

[Hemimegalencephaly and pathological left handedness. A case report].

INTRODUCTION: Hemimegalencephaly is a disorder of neurone proliferation and migration, associated with excessive growth of all or part of one cerebral hemisphere, and variable degrees of pachygyria, polymicrogyria, neuronal heterotopy and gliosis of white matter. It is considered to be a rare malformation with severe encephalopathy, epilepsy resistant to treatment started early, contralateral hemiparesia and severe retardation of development. However, there may also be milder forms. The syndrome of pathological left handedness is associated with disorders of language, visuo-spatial changes and weakness and hypertrophy of the right limbs, with no family history of left handedness. It occurs in lesions predominantly of the left hemisphere which have occurred in the first six years of life. CLINICAL CASE: A 12 year old girl presented with a syndrome of pathological left-handedness and craniofacial asymmetry of the left hemisphere. MR showed the left ventricle and hemisphere to be of increased size and with focal hyperintensity in the white matter, and at the level of the left parietotemporoccipital region there was a thick cortex with little interdigitation of white and grey matter. CONCLUSIONS: Minor forms of hemimegalencephaly are probably more frequent than is generally believed. A high index of suspicion is necessary to identify them. They should be considered in cases of left handedness, craniofacial or bodily asymmetry, cutaneous hamartomas, persistent electroencephalographic asymmetry and asymmetry on neuroimaging with an enlarged ventricle and homolateral hemisphere. Study of this may give information which is useful for understanding plasticity and mechanisms of recovery and functional compensation of immature nerve tissue.

Brain↗

Left-handedness and immune disorders in familial dyslexics.

We examined the frequency of left-handedness, various immune disorders, and comparison disorders in 87 dyslexics and 86 nondyslexics from 14 extended dyslexic families. These families were participants in our genetic linkage studies of dyslexia, which found linkage to chromosome 15 in some families but not others. In the present study, we found a significant elevation of both autoimmune and allergic disorders in the dyslexics only, but no elevation in mixed- or left-handedness in either group. Moreover, the frequency of immune disorders was not higher in the mixed- or left-handed subjects. There was also no elevation in the comparison disorders, which argues against an overreporting bias. The elevation of immune disorders did not vary with linkage status, arguing against a common cause for dyslexia and immune disorders. These findings are discussed in light of Geschwind's hypothesis of a testosterone-mediated association within families between left-handedness, immune disorders, and dyslexia.

Autoimmune Diseases↗

Handedness and esotropia.

Questionnaires were completed by 1083 nonesotropic control subjects and 170 patients with nonparalytic esotropia to determine handedness. The subjects, who had been drawn from patients attending ophthalmic clinics and private practices, were classified as right-handed, left-handed, or ambidextrous based on their answers to five questions about hand preference. Analysis of the results indicated that the handedness of patients with esotropia differed significantly from that of nonesotropic controls. The difference resulted primarily from an excess of non-right-handers among those with esotropia. Non-right-handedness is probably a marker of anomalous cerebral dominance and the disproportion of left-handed and ambidextrous subjects with esotropia may indicate that some persons with esotropia have anomalous brain architecture. In such cases, the structural anomalies might be the cause of the strabismus.

Adolescent↗

Handedness, symptom reporting, and accident susceptibility.

A cross-sectional design was used to examine the relationship among handedness, self-reported symptoms, and accident susceptibility in a nonclinical sample (N = 285). Left-handedness was not found to be associated with elevated symptom reporting (and, consequently, health problems) and accident susceptibility. Thus, the present findings do not support the hypothesis that left-handedness is accompanied by reduced physical fitness or accident proneness.

Accident Proneness↗

Intracellular handedness in ciliates.

Ciliated protozoa have intrinsically asymmetrical ciliary structures that are asymmetrically arranged over the cell surface. These structures can be arranged in two enantiomorphic configurations, 'right-handed' (RH) and 'left-handed' (LH). Whereas one of these configurations (arbitrarily, RH) is apparently universal in Nature and predominant in the laboratory, mirror-image (RH-LH) doublets and reverse (LH) singlets have been generated and studied in eight different ciliate genera. In all these, the internal asymmetry of individual ciliary structures remains normal even when the asymmetry of arrangement of these structures is reversed. The individual structures may sometimes become inverted (rotationally permuted). LH forms reproduce themselves if they are able to feed, or reorganize periodically before starving to death if they are not. Changes of cellular handedness depend upon unusual geometric configurations and in most cases are unrelated to genic changes. In hypotrich ciliates changes of handedness can be provoked by artificially generated juxtapositions of anterior and posterior cell regions or of right and left cell margins. Reversal of handedness in ciliates can be visualized as a consequence of (re-)establishment of a normal sequence of normally spaced positional values following geometric disturbances created by the experimenter or by the regulating cell.

Animals↗

Handedness differences in body image distortion and eating disorder symptomatology.

OBJECTIVE: Previous research has shown decreased access in strong right-handers to processes lateralized to the right cerebral hemisphere. The current studies tested the hypothesis that decreased access to right hemisphere processes, as indexed by increasing strength of right-hand preference, is associated with deficits in body image representation. METHOD: Experiment 1 measured individual's perceived versus actual BMI values. Experiment 2 involved the administration of the Eating Disorders Inventory-2 (EDI-2). RESULTS: Experiment 1 revealed that strong right-handedness was associated with a larger discrepancy between actual and perceived BMI, relative to mixed-handedness. In Experiment 2, strong-handers scored higher on the EDI-2 than did mixed-handers. CONCLUSION: The results indicate that strong degrees of handedness are associated with deficits in accurate representation of body image and with increased eating disorder symptomatology in a nonclinical sample. Implications for research into the neural bases of eating disorders are discussed.

Adult↗

A method for establishing the handedness of biological macromolecules.

When biological macromolecules are imaged in the transmission electron microscope (TEM), their inherent handedness is lost because the three-dimensional (3D) structure is projected onto a two-dimensional (2D) plane, and identical 2D projections can be made from either 3D enantiomer. Nevertheless, tilt experiments in the TEM can be used to determine handedness. These experiments have been performed successfully on negatively stained specimens. More recently, the method was applied to unstained, frozen-hydrated specimens imaged by means of cryoelectron microscopy (cryoTEM) methods. Tilt experiments involve recording two micrographs of the same particles at different tilt angles, computing enantiomeric reconstructions from particle images in one micrograph, predicting orientations of corresponding particles in the second micrograph, and comparing model projections with particle images in the second micrograph. In principle, this procedure can be used to determine the handedness of any biological macromolecule imaged by cryoTEM, provided the enantiomeric reconstructions are distinguishable.

Freezing↗