Management of intermittent exotropia.
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BACKGROUND AND PURPOSE: Studies support techniques of intraoperative adjustment under general anesthesia, of eye muscle surgery, based upon the rest position (deviation) to improve surgical results. None, however, have examined the (a)symmetry, per se, of the rest position and its influence on surgical outcomes. METHODS: Retrospective/prospective patient chart data and photographs taken of patients under anesthesia were judged for (a)symmetry of deviation and correlated with (a)symmetry of surgery performed on 51 exotropic patients. Two groups were compared: "matched" (symmetrical surgery for symmetrical deviations and asymmetrical surgery for asymmetrical deviations) and "opposite" in which the reverse was performed. RESULTS: Sensory results were "statistically significantly" better (p=0.027), the need for postoperative adjustment of adjustable sutures was "statistically significantly" less (p=0.031) and the motor results tended to be improved (p=0.237) ("clinically/medically significant") when surgery was "matched" to the deviation under anesthesia. CONCLUSION: Use of the (a)symmetry of deviations under anesthesia can improve surgical results. Therefore, the final decision as to which muscles to operate on might best be delayed until the time of surgery when that (a)symmetry can be observed. This pilot study should be confirmed by a proper completely prospective randomized study.
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PURPOSE: We report a child with retinal dystrophy and congenital (a)periodic alternating nystagmus (APAN) who responded immediately with improved visual function and electrooculographic parameters after taking the psychopharmacologic stimulant Dexedrine Spansule (Glaxo-Smith Kline, NC, USA) as part of treatment for his Attention Deficit Disorder. DESIGN: Interventional case report. METHODS: General ophthalmic, ocular motor and sensorimotor examinations and ocular motility recordings were performed before and after administration of the drug Dexedrine Spansule. RESULTS: The patient's binocular visual acuity improved only at 1.5 after medicine hours from 20/63 to 20/50, his exotropic deviation decreased from 25 to 10 prism diopters, his stereopsis increased from none to 800 sec/arc and ocular motility recordings showed increased foveation periods and more and lengthened APAN transition/null zones. CONCLUSION: For unexplained reasons the stimulant Dexedrine "paradoxically" improved the nystagmus, binocular function and visual acuity in this patient with retinal dystrophy and congenital nystagmus. This observation may be the basis for investigation of a new pharmacological treatment approach to patients with congenital nystagmus or strabismus.
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30 patients of intermittent ACDS were studied prospectively for a period of 8 weeks to 1 year to evaluate the role of orthoptics in the management of these cases. In patients with convergence insufficiency and a maximum deviation of 25 PD or less the orthoptic treatment was found to be effective in offering symptomatic relief and improving binocular functional status. A reduction in the maximum angle of deviation by 4 PD to 8 PD was observed in 4 patients. Even though the basic angle of deviation remained unchanged in most of the patients, significant functional and symptomatic improvement was obtained in 64% to 85.7% of these cases. The long term stability of these results remains to be studied. In patients with a deviation of more than 25 PD there was no significant improvement in symptoms or reduction in maximum angle of deviation. In 6(37.5%) of these patients some improvement in the fusional range could be demonstrated on the synoptophore without any symptomatic relief.
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