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At least 271 records · Page 15Linked to original sources
PubMed1987

Multicentric human papillomavirus infections of the female genital tract: correlation of viral types with abnormal mitotic figures, colposcopic presentation, and location.

Human papillomavirus deoxyribonucleic acid (DNA) was identified by Southern blot hybridization in 21 of 24 patients with multicentric anogenital lesions and in 46 of 61 individual lesions. Type 6/11 was present in nine patients, type 16 in one, an undetermined type in one, and more than one type in ten patients. Mixed types were present in eight of 46 virus-positive individual lesions. Abnormal mitotic figures were found in 16, 87, and 75% of lesions associated with type 6/11, type 16, and mixed types, respectively. Colposcopic presentation or location of lesions was not predictive of viral types. The relatively high rate of mixed human papillomavirus types in multicentric lesions and in single lesions, and the lack of absolute correlation between viral types and abnormal mitotic figures, suggest that lesions should be removed to prevent viral transmission and possible progression to carcinoma.

Biopsy↗
PubMed1988

[Peroperative colposcopic examination of conization tissue. Determination of the complete or incomplete nature of the cone].

The authors describe an original technique which makes it possible for them to determine during the operation whether conisation has been complete or incomplete. The tissue removed is examined during the operation colposcopically after it has been stained with an aqueous solution of toluidine colour blue. Pathological epithelium can be recognized easily and it is possible to measure the distance between the edge of this epithelium and the tissue that has been removed. If it is inadequate more can be cut out immediately. The distance should be at least 5 mm from the edge of the pathological epithelium.

Carcinoma in Situ↗
PubMed1985

Endocervical curettage as a routine part of colposcopic examinations for abnormal cervical cytology.

Two hundred seven consecutive patients with adequate colposcopy and routine endocervical curettage (ECC) were evaluated for abnormal cervical cytology. A positive ECC was found in 31 patients (15.0%). In patients with grade III cervical intraepithelial neoplasia (CIN), ECC was positive 260% more often than in patients with CIN 1 and 2 (P less than .005). The ECC was the only evidence of dysplasia in three instances. The data suggest that routine ECC should be an integral part of the colposcopic examination of patients with abnormal cytology.

Biopsy↗
PubMed1984

Colposcopic pictures in cervical intraepithelial neoplasia grade III.

This study concerns 414 women affected by cervical intraepithelial neoplasia grade III. In each case we have considered and compared the colposcopic examination and the cyto-histologic type of lesion. Ectopy and/or typical transformation prevail in atypical metaplasia. Leukoplakia has its highest incidence in severe dysplasia, is prominent in severe dysplasia and carcinoma in situ unless these two lesions are combined atypical metaplasia. The mosaic prevails in atypical metaplasia, but appears in a prominent form in carcinoma in situ only, whereas the punctation prevails in carcinoma in situ. When the suspect white areas appear in association their incidence in the various CIN III lesions they do not vary. The red suspect areas are rather infrequent, while the atypical transformation is absent in atypical metaplasia, fairly frequent in carcinoma in situ and prevails significantly in microinvasive carcinoma.

Adolescent↗
PubMed1983

The colposcopy clinic in a residency training program. Five years' experience with colposcopically directed biopsies followed by conization or hysterectomy.

Five hundred fifty-four patients with abnormal cytologic smears were screened in a special clinic by gynecology residents under faculty supervision using colposcopy and biopsies. Two hundred fifty patients who were evaluated by colposcopy subsequently had conization or hysterectomy. Colposcopically directed biopsies were accurate (comparable to the surgical specimen) in 92%. Three patients had invasive cancer high in the endocervical canal that was found by conization after endocervical curettage and colposcopy had indicated less-severe disease. Persistent or recurrent dysplasia was found in approximately 5% after conization and in none after hysterectomy. Because 23% of patients were lost to follow-up after treatment and an additional 19% had inadequate follow-up, management of CIN III with local destruction (cryocautery, electrocautery, laser) does not seem advisable.

Adolescent↗
PubMed1982

Colposcopic and histologic findings in cervical chlamydial infection.

Colposcopic and histologic findings in 41 patients with Chlamydia trachomatis-associated cervicitis and in age-matched controls with nonspecific cervicitis are presented. Colposcopy showed exophytic follicular cervicitis in 30 patients in the chlamydia group and in none in the control group. Atypical transformation zone occurred significantly more often in the chlamydia group. Directed biopsy specimens revealed cervical intraepithelial neoplasia in 10 cases in the chlamydial group but in only 1 case in the control group. In 4 patients with chlamydial cervicitis lymphoid follicles were observed in histologic specimens.

Adult↗
PubMed1981

[Papillomas of the lower female genital organs - incidence, colposcopic and histological findings - oncogynaecological relevance (author's transl)].

Reference is made to findings recorded by the authors from 39 cases of vulvar, vaginal, and cervical papillomas. An account is given of the clinical, colposcopic, and histomorphological criteria which to differentiate genuine papilloma from acuminate condyloma. The great oncogynaecological importance of cervical and vaginal papillomas is underlined. Epithelial dysplasia up to transition to intra-epithelial and infiltrative papillary carcinoma was histologically recorded from more than 50 per cent of all cases.

Adult↗
PubMed1980

Therapeutic conization under colposcopic guidance in the operating room.

One hundred eight patients with "satisfactory" colposcopy, a histologic diagnosis of cervical carcinoma in situ and a stated desire to maintain fertility were treated by therapeutic conization performed under colposcopic guidance in the operating room. One patient had a recurrence of carcinoma in situ at 8 months, and two patients had mild dysplasia at 18 and 24 months. Fifteen patients conceived.

Adolescent↗
PubMed1995

[Treatment of condylomata acuminata of the male reproductive organs with CO2 laser under colposcopic control].

The first results of laser therapy in treatment of condylomata acuminata of male reproductive organs are reported. Between November 1991 and December 1993 in Department of Reproduction, Institute of Gynecology and Obstetrics, Karol Marcinkowski University School of Medical Sciences, Poznań in nine patients with condylomatous changes of reproductive organs CO2-laser therapy under colposcopic control was done. In 7 of them the healing was achieved. In two patients second laser therapy was done. All patients are still under control in Department of Reproduction and there was no recurrence diagnosed.

Adult↗
PubMed1995

Vulvar and vaginal colposcopic pictures of human papillomavirus infection.

The recognition of both overt and subclinical vulvar HPV infection has become increasingly important. However, although molecular biological evidence has indicated a strong link between HPVs and cancer, clinical or epidemiological evidence is still not fully convincing. We studied 159 HPV DNA positive patients, using a dot blot hybridization technique (ViraPap and ViraType, Digene Diagnostics. USA), and 69 randomly selected HPV negative controls drawn from the same clinical setting, at the outpatient clinic, Department of Obstetrics and Gynecology, University Central Hospital, Helsinki, Finland. Seven patients had HPV 6/11, 51 had HPV 16/18, 52 had HPV 31/33/35 25 had more than one of the three HPV DNA groups ("mixed"), and 24 had untypable HPV DNA. Cases and controls were examined at four month intervals. The mean follow-up time was 12.2 months (SD 8.7) for the cases, and 12.8 (SD 6.9) for the controls. Although vulvar or vaginal abnormalities (acetowhite epithelium, squamous papillomatosis, filaments, satellite lesions, fissure, papules, or exophytic condylomas) were more commonly seen in the cases than in the controls, the difference was significant only for exophytic condylomas. In conclusion, colposcopy is not a good predictor of HPV infection and should not be used as an HPV screening test. HPV DNA hybrodization did not help more than the histopathologic findings in the diagnosis, but allowed the recognition of high-risk patients. The role of an accurate colposcopic examination with target biopsies remains essential.

Adult↗
PubMed1995

Colposcopically directed biopsy and loop excision of the transformation zone. Comparison of histologic findings.

We performed a retrospective comparison between the findings from colposcopically directed biopsies and those from loop excision of the transformation zone (LETZ) specimens. The correlation was satisfactory. When a low grade squamous intraepithelial lesion (SIL) was predicted on a cytologic smear and biopsy specimen, no cases of invasive carcinoma were found. In two (0.8%) cases in which a high grade SIL was predicted on the cervical smear and biopsy, microinvasive carcinoma was found in the LETZ specimen.

Adolescent↗
PubMed1994

[Cervical intraepithelial neoplasia III treated with CO2 laser. Cytological, colposcopic and histopathological follow-up].

An study with 52 patients, was performed at the colposcopy Service, Hospital López Mateos, IMSS. The patients presented with an histological diagnosis of cervical in situ carcinoma. They were, previously, submitted to a colposcopic and cytological protocol study. All the patients were treated with removal of a cervical cylinder with CO2 laser. The post-operative follow up reported: Altogether normal and inflammatory reports on cytology, colposcopy and histology, 78.2%, 89.1%, and 91.2%, respectively. Therefore, it is concluded that this treatment is adequate and with a satisfactory cure rate.

Adult↗
PubMedDate not supplied

Enhancement of colposcopic image by sulphosalicylic acid.

Acetic acid is used conventionally for enhancement of the colposcopic image. We used sulphosalicylic acid instead of acetic acid in 50 normal cases. The normal appearance was enhanced in all cases. The image was also enhanced in 70% cases of cervical intraepithelial neoplasia and 90% cases of cervical condyloma accuminata. The image was not inferior to that with acetic acid in any of the cases.

Acetates↗
PubMed1977

The significance of age in the colposcopic evaluation of women with atypical apanicolaou smears.

As women age, atypical Papanicolaou smears are associated with more advanced cervical neoplasia. The woman under age 30 had less than one chance in a hundred of having invasive carcinoma if she has an atypical Papanicolaou smear, while the woman over age 60 has one chance in six of this finding. An atypical Papanicolaou smear does not necessarily mean neoplasia is present; 23% of the women evaluated for atypical smears had a negative evaluation, and this included women over age 60. Endocervical currettings containing neoplastic tissue frequently are seen after age 30 and may contribute significant information to the final diagnosis; stenosis of the endocervix, however, may prevent curettage in postmenopausal women. Diagnostic conizations of the cervix rarely are necessary prior to age 30 if colposcopic technics are used. The need for conizations increases by decade of age and is required in at least one-third of postmenopausal women evaluated initially by colposcopy.

Adolescent↗
PubMed1993

Colposcopic differentiation of abnormalities arising in the transformation zone.

When metaplastic cervical epithelium is exposed to the factors responsible for neoplasia, the transformation zone becomes atypical. These changes, visible as acetowhite epithelium, altered vascular patterns, and irregular surface contour, are easily recognized through the colposcope in most patients. It is possible to grade the changes to determine the severity of the abnormality and so, in consultation with the patient, decide on the best management course. However, there will always be lesions where colposcopy is indeterminate, and biopsy of such lesions is mandatory. Combined colposcopy and histology are still the mainstays of clinical management. As yet, more refined investigations, such as HPV-subtype determination, have not demonstrated any advantage for these patients.

Adult↗
PubMed1993

[Colposcopical and pathological study of vulvar pseudocondyloma].

One hundred and forty seven cases of pseudocondyloma, which were diagnosed by colposcopy and histopathology, and 129 cases of condyloma as control group were studied. Pseudocondyloma showed colposcopically as crowded together distribution of single papilla or vesiculated papules without branching structure and capillary loops. The color of the lesions is unchanged after acetic acid stain. The lesions can be divided into vesicular proliferative type and ciliary proliferative type. Differing from condyloma, pseudocondyloma lesions showed histopathologically only slight proliferation of squamous epithelium, lack of diagnostic koilocytes and negative result in HPV immunohistochemical study and hybridization of HPV-DNA. It is a reliable method to make a diagnosis of pseudocondyloma by colposcopy and histopathology.

Adolescent↗
PubMed1995

Postmenopausal vulvar pruritus--colposcopic diagnosis and treatment.

Vulvar pruritus is a common symptom in post-menopausal women and treatment is easy if the diagnosis is duly recognized. The purpose of this study is to show the importance of colposcopic examination and directed biopsies in 27 post-menopausal women with pruritus. Biopsy sites were selected by colposcopy. The prevalence of vulvar pruritus, vulvar pathologies, vulvar dystrophies and vulvar intraepithelial lesions (VIN) were 2.18%, 1.49%, 0.94% and 0.07% respectively. Vulvar dystrophies were treated by topical steroids and success rate was 100%. All patients with vulvar pruritus need examination under colposcopy to define optimal therapy and to exclude atypia or malignancy.

Adrenal Cortex Hormones↗