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Mapping brain maturation and cognitive development during adolescence.

Non-invasive mapping of brain structure and function with magnetic resonance imaging (MRI) has opened up unprecedented opportunities for studying the neural substrates underlying cognitive development. There is an emerging consensus of a continuous increase throughout adolescence in the volume of white matter, both global and local. There is less agreement on the meaning of asynchronous age-related decreases in the volume of grey matter in different cortical regions; these might equally represent loss ("pruning") or gain (intra-cortical myelination) of tissue. Functional MRI studies have so far focused mostly on executive functions, such as working memory and behavioural inhibition, with very few addressing questions regarding the maturation of social cognition. Future directions for research in this area are discussed in the context of processing biological motion and matching perceptions and actions.

Adolescent↗

Towards an integrated approach to lung health in adolescents in developing countries.

The World Health Organization strategies, Integrated Management of Childhood Illness and Practical Approach to Lung health provide assessment and management guidelines for health workers in developing countries. We reviewed issues important to lung health in adolescents to highlight whether differences in factors such as adolescent behaviour have consequences for the development of case management guidelines, to form a bridge between guidelines for younger children and for adults and to make suggestions for further study. Pneumonia, asthma and tuberculosis are the leading lung health problems in adolescents. As countries industrialise, the importance of asthma mortality and morbidity increases as that of pneumonia and pulmonary tuberculosis decreases. Guidelines for managing pneumonia and asthma in children and adults in developing and developed countries should be adaptable for use in adolescents in developing countries, although more information is needed on predictors of severity such as respiratory rate cut-offs, level of fever, hypotension, malnutrition and level of consciousness. The effectiveness of low-cost treatment for asthma should be explored further. HIV and the global resurgence of tuberculosis pose significant challenges for improving adolescent lung health, and prevention of smoking initiation during adolescence is a priority goal of any integrated approach to improving lung health.

Adolescent↗

Genetics and developmental psychopathology: 2. The main effects of genes and environment on behavioral problems in the Virginia Twin Study of Adolescent Behavioral Development.

Little is known about the contribution of genetic and environmental factors to risk for juvenile psychopathology. The Virginia Twin Study of Adolescent Behavioral Development allows these contributions to be estimated. A population-based, unselected sample of 1412 Caucasian twin pairs aged 8-16 years was ascertained through Virginia schools. Assessment of the children involved semi-structured face-to-face interviews with both twins and both parents using the Child and Adolescent Psychiatric Assessment (CAPA). Self-report questionnaires were also completed by parents, children, and teachers. Measures assessed DSM-III-R symptoms of Attention Deficit Hyperactivity Disorder (ADHD). Conduct Disorder, Oppositional Defiant Disorder, Overanxious Disorder, Separation Anxiety, and Depressive Disorder. Factorially derived questionnaire scales were also extracted. Scores were normalized and standardized by age and sex. Maximum likelihood methods were used to estimate contributions of additive and nonadditive genetic effects, the shared and unique environment, and sibling imitation or contrast effects. Estimates were tested for heterogeneity over sexes. Generally, monozygotic (MZ) twins correlated more highly than dizygotic (DZ) twins, parental ratings more than child ratings, and questionnaire scales more highly than interviews. DZ correlations were very low for measures of ADHD and DZ variances were greater than MZ variances for these variables. Correlations sometimes differed between sexes but those for boy-girl pairs were usually similar to those for like-sex pairs. Most of the measures showed small to moderate additive genetic effects and moderate to large effects of the unique individual environment. Measures of ADHD and related constructs showed marked sibling contrast effects. Some measures of oppositional behavior and conduct disorder showed shared environmental effects. There were marked sex differences in the genetic contribution to separation anxiety, otherwise similar genetic effects appear to be expressed in boys and girls. Effects of rater biases on the genetic analysis are considered. The study supports a widespread influence of genetic factors on risk to adolescent psychopathology and suggests that the contribution of different types of social influence may vary consistently across domains of measurement.

Adolescent↗

Panic disorder in children and adolescents: new developments, new directions.

Reviewed panic attacks and panic disorders in children and adolescents critically and highlighted new developments. It is concluded that panic attacks and panic disorder are common in adolescence and that they are responsive to cognitive-behavioral treatment regimens. It is also concluded that although panic attacks and panic disorder are less common in children, they are nonetheless present. It is important to note, however, that their expression in childhood may vary from the clinical features seen in adolescence and adulthood. Specifically, it is suggested that most panic attacks in childhood are associated with particular events and are not unexpected or "out of the blue." Moreover, noncatastrophic interpretations of the symptoms of panic prevail. A developmental model for the onset, course, and correlates of panic in children is put forth.

Adolescent↗

Criminal decision making: the development of adolescent judgment, criminal responsibility, and culpability.

Theories of judgment in decision making hypothesize that throughout adolescence, judgment is impaired because the development of several psychosocial factors that are presumed to influence decision making lags behind the development of the cognitive capacities that are required to make mature decisions. This study uses an innovative video technique to examine the role of several psychosocial factors--temporal perspective, peer influence, and risk perception--in adolescent criminal decision making. Results based on data collected from 56 adolescents between the ages of 13 and 18 years revealed that detained youth were more likely to think of future-oriented consequences of engaging in the depicted delinquent act and less likely to anticipate pressure from their friends than nondetained youth. Examination of the developmental functions of the psychosocial factors indicates age-based differences on standardized measures of temporal perspective and resistance to peer influence and on measures of the role of risk perception in criminal decision making. Assessments of criminal responsibility and culpability were predicted by age and ethnicity. Implications for punishment in the juvenile justice system are discussed.

Adolescent↗

Adolescent growth, development, and psychosocial aspects of sports participation: an overview.

This chapter examines sports participation in the context of adolescent growth and development. Because the nature of sports participation is highly organized and competitive, it is imperative that parents, coaches, physicians, and other clinicians remember that they may be placing increased pressures on the adolescent to perform and practice. The authors review the impact of physical growth and psychosocial development and also describe how substance abuse, depression, and aggressive behavior may or may not be influenced by sports participation.

Adolescent↗

Alcohol consumption and associated problems in a birth cohort of 15 year olds.

AIMS: This study documents patterns of alcohol consumption and alcohol abuse in a birth cohort of 965 Christchurch born children studied to the age of 15 years. Additionally, the study documents the associations between measures of alcohol consumption and a range of other aspects of adolescent development. METHOD: Data on patterns of alcohol use, alcohol related problems and other aspects of adolescent development were collected at age 15 years on the basis of self report, parental reports and official records. RESULTS: For most sample members the consumption of alcohol was both infrequent (28.4% were classified as nondrinkers and 23.9% had drunk alcohol only once or twice in the preceding year) and moderate. However, 6.7% reported weekly drinking and 3.3%-6.8% of the sample reported drinking the equivalent of at least 90 mL of pure alcohol on the last or typical drinking occasion. 19.1% of the sample reported experiencing problems as a result of their drinking and 4.9% of the sample met criteria for alcohol abuse. Measures of alcohol consumption were found to be highly associated with measures of daily cigarette smoking, cannabis use, sexual activity, police contact and depression. CONCLUSIONS: While overall levels of alcohol consumption in this cohort were moderate there was evidence of a minority of adolescents who consumed alcohol frequently, in large amounts or who experienced alcohol related problems. Measures of frequent, heavy or problem alcohol use were found to be highly associated with a range of other aspects of adolescent development.

Adolescent↗

Development and evaluation of a short-term training design for health professionals.

A study was conducted to assess how a training program on adolescent development affected health professionals and their work performance. Several mechanisms were used to evaluate the impact of the workshop. Changes in trainees' attitudes and knowledge about adolescent development were measured with pre- and posttraining tests. For five test components: attitude, psychosocial, cognitive, general knowledge and case study applications, the cognitive section differentiated significantly between trainee and comparison groups. On-site observations and interviews were conducted to gauge whether training information was incorporated and applied within the job setting. Short-term training, evaluated at six weeks posttraining, affected basic theoretical knowledge of adolescent development, which in turn improved morale through greater understanding of the complexities of adolescent behavior. Moreover, the evaluation process itself was an effective teaching mechanism, since the various evaluation components interacted with the workshop materials, creating a more comprehensive learning experience for the participants. On-site observations demonstrated that application of workshop materials was often constrained at the work site. Additional practice, organizational support for training objectives and extensive follow-up may be necessary to assure that training materials are applied at the work site.

Adolescent↗

Correlations between neonatal body weight and adolescent brain development in rats.

Correlations between neonatal body weight, and body weight and several brain parameters at 30 days of age were studied in normal rats. At 30 days ('adolescence') cortex has already reached its final thickness and the rat exhibits long-term memory. Brain parameters included cerebral weight, DNA, protein and cholesterol contents and densities, as well as cortical and cerebral dimensions (cerebral sections). As expected, most of these parameters in 30-day-old animals were significantly correlated with each other. Unexpectedly, neonatal body weight was also significantly correlated with cholesterol content and density at 30 days, as well as with cortical and cerebral dimensions at 30 days. Thus, statistically, neonatal body weight already predetermines the extent of neuronal (cerebral) development at adolescence (30 days). This finding also makes it possible to make at birth statistical predictions about future brain development without having to sacrifice neonatal animals.

Animals↗

Neuropsychological development in adolescents: cognitive and emotional model for considering risk factors for adolescents with cleft.

This article reviews neurologic, endocrinologic, and neuropsychological developments that affect our understanding of the adolescent patient. Neuroimaging and neuroradiologic techniques have assisted in identifying brain-behavior relationships and how different neuropsychological patterns result in different ways of thinking. Psychoneuroendocrinologic studies have shown that sex differences in maturation and hormonal effects on behavior need taking into account. At adolescence, the individual with a cleft or craniofacial condition may be at risk for adjustment problems due to earlier developmental events, which may affect language, behavior, and self-esteem.

Adolescent↗

Foreskin development before adolescence in 2149 schoolboys.

BACKGROUND: We examined the external genitalia of 2149 elementary schoolboys in the suburban area of Taichung in Taiwan for an understanding of foreskin development before adolescence. METHODS: The study's subjects comprised 692 first-grade boys, 725 fourth-grade boys, and 732 seventh-grade boys. The foreskin's condition was classified as: type I (normal prepuce), type II (adhesion of prepuce), type III (partial phimosis), type IV (phimosis) and type V (circumcised foreskin). Other abnormalities of the genitalia also were recorded. All of the examinations were performed by the same urologist. RESULTS: The incidence of type I foreskin was 8.2% in first-grade boys, 21.0% in fourth-grade boys, and 58.1% in seventh-grade boys. The incidence of type IV foreskin was 17.1% in first-grade boys, 9.7% in fourth-grade boys, and 1.2% in seventh-grade boys. Only one boy had balanoposthitis. Other abnormalities included inguinal hernia (n = 2), hydrocele (n = 12), cryptorchitism (n = 8), varicocele (n = 22), and subcoronal-type hypospadia (n = 1). CONCLUSIONS: Physiological phimosis declines with age. Most boys with phimosis in this study did not require treatment.

Adolescent↗

Adolescent sex and mass media: a developmental approach.

Media critics point to adolescents' exposure to "sexy" television and popular music. Developmental transitions lead to increased information seeking, and developmental tasks force adolescents to find information sources other than their parents, implying a link between sexy media and adolescent development. Media research informed by knowledge of adolescent development may be able to clarify this connection, and model development is discussed here.

Adolescent↗

Delaying second births among adolescent mothers: a randomized, controlled trial of a home-based mentoring program.

CONTEXT: Rates of rapid second births among low-income black adolescent mothers range from 20% to 50%. Most efforts to prevent rapid second births have been unsuccessful. OBJECTIVES: There were 4 objectives: (1) to examine whether a home-based mentoring intervention was effective in preventing second births within 2 years of the adolescent mother's first delivery; (2) to examine whether greater intervention participation increased the likelihood of preventing a second birth; (3) to examine whether second births were better predicted from a risk practice perspective or a family formation perspective, based on information collected at delivery; and (4) to examine how risk practices or family formation over the first 2 years of parenthood were related to a second birth. DESIGN: We conducted a randomized, controlled trial of a home-based intervention curriculum, based on social cognitive theory, and focused on interpersonal negotiation skills, adolescent development, and parenting. The curriculum was delivered biweekly until the infant's first birthday by college-educated, black, single mothers who served as mentors, presenting themselves as "big sisters." The control group received usual care. Follow-up evaluations were conducted in the homes 6, 13, and 24 months after recruitment. METHODS: Participants were recruited from urban hospitals at delivery and were 181 first time, black adolescent mothers (< 18 years of age); 82% (149 of 181) completed the 24-month evaluation. RESULTS: Intent-to-treat analyses revealed that control mothers were more likely than intervention mothers to have a second infant. The complier average causal effect was used to account for variability in intervention participation. Having > or = 2 intervention visits increased the odds of not having a second infant more than threefold. Only 1 mother who completed > or = 6 visits had a second infant. At delivery of their first infant, mothers who had a second infant were slightly older (16.7 vs 16.2 years) and were more likely to have been arrested (30% vs 14%). There were no differences in baseline contraceptive use or other measures of risk or family formation. At 24 months, mothers who had a second infant reported high self-esteem, positive life events, and romantic involvement and residence with the first infant's father. At 24 months, there were no differences in marital rates (2%), risk practices, or contraceptive use between mothers who did and did not have a second infant. Mothers who did not have a second infant were marginally more likely to report no plans for contraception in their next sexual contact compared with mothers who had a second infant (22% vs 8%, respectively). CONCLUSIONS: A home-based intervention founded on a mentorship model and targeted toward adolescent development, including negotiation skills, was effective in preventing rapid repeat births among low-income, black adolescent mothers. The effectiveness of the intervention could be seen after only 2 visits and increased over time. There were no second births among mothers who attended > or = 8 sessions. There was no evidence that risk behavior or contraceptive use was related to rapid second births. There was some evidence that rapid second births among adolescent mothers were regarded as desirable and as part of a move toward increasing autonomy and family formation, thereby undermining intervention programs that focus on risk avoidance. Findings suggest the merits of a mentoring program for low-income, black adolescent mothers, based on a relatively brief (6-8 sessions) curriculum targeted toward adolescent development and interpersonal negotiation skills.

Adolescent↗

Pubertal androgen therapy in boys.

Anabolic-androgenic steroids (AAS) are necessary for normal male sexual differentiation and development and pubertal development. Androgen therapy is appropriate for boys with delayed development (constitutional delay of growth and puberty, CDGP) as well as those with primary or secondary hypogonadism. The principal goal is to restore the serum testosterone (T) level to the normal range at each stage of adolescent development and then to the normal adult range if the hypogonadism is permanent. In addition the levels of dihydrotestosterone and estradiol should also be within the normal range. One should be able to do that with a wide variety of androgen preparations-injectable, implantable, and cutaneous patches or gels. However, during the transition from prepubertal to adult it is difficult to reliably deliver the relatively small doses of T necessary for adolescent development using any of the cutaneous preparations. Androgen therapy should permit normal linear growth (including the adolescent growth spurt), adolescent sexual development, and the attainment of normal body composition including lean body mass, bone and the appropriate regional distribution of body fat as well as the psychological development appropriate for the stage of adolescent development.

Adolescent↗

Changes in ego and moral development in adolescents: a longitudinal study.

A longitudinal study was designed to examine the relation between Loevinger's measure of ego development and moral development as indexed by Rest's Defining Issues Test in a sample of 123 adolescents at 12 to 14 years of age and four years later. Study I assessed differential rates of change and theoretically predicted directions of change in the two developmental functions and gender differences in ego development. Substantial ego stage movement occurred (60 per cent advancement, 40 per cent stability); moral growth was moderate. Girls scored a half ego stage ahead of boys; patterns of directional change were similar. Ego level and moral development related at either fixed point in time, but ego functioning in early adolescence did not predict subsequent moral development. Study II addressed adolescents' perceptions of parenting styles in relation to these social cognitive functions. Parental behaviours that involve loving or support related to higher ego levels; parental demanding associated with lower ego development in early adolescence. Traditional gender-related parent socialization was found among girls and boys with greater ego development. The mediating role of perceived childrearing styles was considered in relation to gender differences in ego development.

Adolescent↗