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At least 253 records · Page 14Linked to original sources
PubMed2003

[Sequelae of zygomatic-orbito-maxillary fractures. Report of 70 cases and review of literature].

Fractures of the zygomatic-orbito-maxillary complex (ZOM) are among the most frequent in maxillo-facial surgery. The study evaluates treatment for this type of fracture in the long-term and the sequelae linked to it. Patients who had been operated between february 1998 and november 1999 to reduce and retain ZOM fractures were subjected to check-up examination at the Maxillo-Facial Surgery Operative Unit, Florence. Cases selected had been operated via trans-oral access with incision of the superior vestibular fornix and where necessary with application of means of retention (Foley balloon and/or wire or plate-and-screw osteosynthesis). In these patients, the presence of residual deformities was evaluated together with enophthalmos, diplopia, compromised mouth opening if present, inflammation of the mucosa of the maxillary sinus, and above all incidence of sensory deficit in the distribution area of the infra-orbital nerves and the dental plexus. Particular attention was paid to evaluating tooth sensitivity on the side involved by the trauma, for any damage of the dental plexus. The most frequent sequela found in our group was lesion of the infra-orbital nerves, and a lower percentage of other sequelae such as residual deformities, enophthalmos or diplopia. Interestingly, in all cases in our series there was a significant reduction in tooth sensitivity on the side of the lesion, above all in the anterior sectors.

Adult↗
PubMed1992

[Sequelae of osteoarthritis of the hip in growing children. Apropos of 72 cases].

The authors reviewed a series of 72 hips in 60 children with sequelae of septic arthritis of the hip to evaluate the long term evolution. The average follow up was 7 years 8 months (Range 1Y-17Y). 40 hips were operated and 32 were not. The results were analysed according to clinical and radiological criterions in an attempt to propose a guide for treatment. Sequelae might also occur after both initial treatment with open drainage or aspiration. The study of sequelae according to the factors of severity (organism, age when infected) showed that the evolution of these cases of arthritis cannot be forecast. The authors noticed that very severe roentgenographic lesions could be well tolerated clinically, at least on a medium term basis. They advise great care before operating on dislocated hips when they are clinically well tolerated. Finally the authors insist on 2 little known lesions: caput valgum and caput antetorsum.

Adolescent↗
PubMedDate not supplied

Treatment of the sequelae of septic osteoarthritis of the hip during pediatric age.

A total of 69 cases (73 hips) of the sequelae of septic osteoarthritis of the hip are studied. The sequelae are classified based on whether or not the femoral epiphysis is present, and on stability of the joint according to Hunka (1982). Three of the hips were treated non-surgically. All of the others were submitted to from a minimum of 2 to maximum of 5 operations with the purpose of re-establishing joint relationships. The results were: good: 50 hips (72.5%); fair 12 (17.4%); poor: 11 (16%). The most significant sequelae were hip instability, joint function limitation, and shortening of the limb.

Arthritis, Infectious↗
PubMed1992

The postconcussion syndrome and the sequelae of mild head injury.

The postconcussion syndrome refers to a large number of symptoms and signs that may occur alone or in combination following usually mild head injury. The most common complaints are headaches, dizziness, fatigue, irritability, anxiety, insomnia, loss of consciousness and memory, and noise sensitivity. Mild head injury is a major public health concern because the annual incidence is about 150 per 100,000 population, accounting for 75% or more of all head injuries. The postconcussion syndrome has been recognized for at least the last few hundred years and has been the subject of intense controversy for more than 100 years. The Hollywood head injury myth has been an important contributor to persisting skepticism and might be countered by educational efforts and counter-examples from boxing. The organicity of the postconcussion syndrome has now become well documented. Abnormalities following mild head injury have been reported in neuropathologic, neurophysiologic, neuroimaging, and neuropsychologic studies. There are multiple sequelae of mild head injury, including headaches of multiple types, cranial nerve symptoms and signs, psychologic and somatic complaints, and cognitive impairment. Rare sequelae include hematomas, seizures, transient global amnesia, tremor, and dystonia. Neuroimaging and physiologic and psychologic testing should be used judiciously based on the problems of the particular patient rather than in a cookbook fashion. Prognostic studies clearly substantiate the existence of a postconcussion syndrome. Manifestations of the postconcussion syndrome are common, with resolution in most patients by 3 to 6 months after the injury. Persistent symptoms and cognitive deficits are present in a distinct minority of patients for additional months or years. Risk factors for persisting sequelae include age over 40 years; lower educational, intellectual, and socioeconomic level; female gender; alcohol abuse; prior head injury; and multiple trauma. Although a small minority are malingerers, frauds, or have compensation neurosis, most patients have genuine complaints. Contrary to a popular perception, most patients with litigation or compensation claims are not cured by a verdict. Treatment is individualized depending on the specific complaints of the patient. Although a variety of medication and psychologic treatments are currently available, ongoing basic and clinical research of all aspects of mild head injury are crucial to provide more efficacious treatment in the future.

Adult↗
PubMed1992

[The treatment of the sequelae of penetrating injuries to the esophagus].

On the basis of experience in the treatment of the sequelae of penetrating esophageal injuries in 79 patients the authors divided the patients into 3 groups: those in whom the perforation healed and stricture of the esophagus developed; patients with incurable purulent complications and esophageal fistulas; patients who underwent various operative interventions for acute perforation or its sequelae and needed a reconstructive operation. Recommendations on the choice of adequate therapeutic tactics for each group are given. The method of examination of the patients and the peculiarities of surgical treatment are described in detail. The most frequently encountered complications and the produced results are analysed. It is concluded that patients with sequelae of esophageal perforation must be treated at specialized clinics experienced in the management of this severe condition.

Adolescent↗
PubMed1992

Psychological sequelae of sexually transmitted diseases in adolescents.

Sexually active adolescents are the highest risk group for many of the sexually transmitted diseases. Although clinical presentations, diagnostic methods, and medical sequelae are understood increasingly, psychological sequelae are often neither recognized nor understood. Insight into these issues may prevent repeat episodes of sexually transmitted diseases and limit their spread. This article summarizes the literature regarding psychological issues and sequelae and emphasizes the need for further study.

Adolescent↗
PubMedDate not supplied

Long-term health sequelae following E. coli and campylobacter contamination of municipal water. Population sampling and assessing non-participation biases.

BACKGROUND: Following bacterial contamination of a municipal water system in the rural town of Walkerton, Ontario, over 2,300 cases of acute gastroenteritis were documented. The Walkerton Health Study is currently underway to assess for long-term health sequelae among consenting inhabitants of Walkerton, related to the original outbreak. We explored whether the association between the acute exposure and preliminary long-term health outcomes may have been biased through differences between early- and late-recruited study participants. METHODS: Using multiple data sources, including the 1996 and 2001 Canadian Census, and records from the Regional Health Unit, hospital and Walkerton Health Study, we determined both sample representativeness and the anticipated effects of intensifying study participant recruitment. Selection bias was assessed by examining for differences between initial and late participants, and their subsequent risk of having hypertension, proteinuria and reduced renal clearance. RESULTS: Of the 4,315 participants, 2,756 were permanent residents of Walkerton, representing 55% of the town's total population. The sample was demographically similar to the population of interest, although statistically women were more likely to participate than men (55% of sample were women compared to 52% of population, p<0.01), and the proportion of both young and very elderly adults was smaller than expected (13% of sample were > or = 65 years of age compared to 18% of population, p<0.01). Comparing the initial 3,959 participants to the 356 persons additionally recruited with substantial effort, the latter were more likely to be free of symptoms during the outbreak (21% vs. 7%, p<0.001), but were otherwise similar in terms of age, sex, the use of medical care resources and underlying health state predating the outbreak. The risk of long-term hypertension or renal sequelae did not significantly differ between initial and late study recruits. CONCLUSIONS: Participants in the Walkerton Health Study represent the population of interest, and comprise those who were acutely ill during the infected water outbreak. The available study sample should provide reasonably unbiased estimates of the associated risk between acute bacterial gastroenteritis and long-term health sequelae.

Acute Disease↗
PubMed2005

[State of the art: sequelae of tuberculosis].

Sequela of tuberculosis (TB sequela) is defined as the state with various secondary complications after healing of TB, such as chronic respiratory failure (CRF), cor pulmonale or chronic pulmonary inflammation. Pathophysiology of TB sequelae is consisted of disturbed pulmonary function, CRF, sleep disorder and pulmonary hypertension. In addition, secondary pulmonary infection with mycosis or nontuberculous mycobacteriosis (NTM) is difficult to be controlled.

Antifungal Agents↗
PubMed2006

[Effects of Buyanghuanwu decoction on nerve proliferation in rats with sequelae of ischemic stroke].

OBJECTIVE: To examine the effect of Buyanghuanwu decoction (BYHWD) in inducing nerve proliferation in rats with sequelae of ischemic stroke. METHODS: A rat model of ischemic stroke sequelae was established by means of craniectomy in which the right common carotid artery was ligated with 4-0 silk thread followed by cauterization of the right middle cerebral artery. Programmed electric shock was administered 24 h after the onset of ischemic stroke for 2 h daily for 20 consecutive days. The rats in sham operation group were not subjected to ligation of the right common carotid artery or right middle cerebral artery occlusion. The rats in the treatment groups were given oral BYHWD for 15 consecutive days. All the rats received repeated intraperitoneal injections of the cell proliferation-specific marker 5-bromodeoxyuridine (BrdU), and the intake of BrdU in the cerebral tissues was determined by immunohistochemistry. RESULTS: The number of BrdU-immunoreactive cells in the cerebral tissues of BYHWD-treated rats was significantly greater than that in the untreated model group. CONCLUSION: BYHWD can promote nerve proliferation in rats with ischemic stroke sequelae.

Administration, Oral↗
PubMed2006

[Clinical analysis of patients with sequelae of pulmonary tuberculosis undergoing home oxygen therapy].

PURPOSE: To clarify the clinical characteristics of patients with sequelae of pulmonary tuberculosis undergoing home oxygen therapy. OBJECTS AND METHODS: We conducted a cross-sectional survey of those with newly-introduced home oxygen therapy for the sequelae of pulmonary tuberculosis from 1998 through 2001, using national hospital network of respiratory diseases. RESULTS: The study subjects were 402 in total (271 men and 131 women), who started the home oxygen therapy at the age ranging between 33 and 100 years (72.2 +/- 8.1 years, mean +/- S.D.). They suffered from pulmonary tuberculosis at the mean age of 37.7 +/- 19.4 years, and the interval leading to oxygen therapy averaged 33.1 +/- 19.1 years. Sixty-eight percent of these patients demonstrated body mass index (BMI) less than 20. Pulmonary function studies revealed the markedly-decreased vital capacity (46.2 +/- 15.0%) as well as reduced FEV1/FVC (68.5 +/- 18.8%). Arterial blood gases measured when home oxygen therapy was introduced showed hypoxemia (Pa(O2), 60.4 +/- 10.7 Torr) with hypercapnea (Pa(CO2), 50.5 +/- 9.4 Torr). The average flow rate of oxygen was 0.94 +/- 0.64 L/min at rest and 1.51 +/- 0.70 L/min on exertion. The patients were divided into two groups; those with surgical intervention including thoracoplasty or lung resection (126 cases, group 1) and those without surgery (148 cases, group 2). The mean age of the patients in the group 1 when home oxygen therapy was started was 72.3 +/- 6.4 years and 71.6 +/- 9.1 years in the group 2, respectively. Subjects in group 1 were more likely suffered from TB in younger age than those in group 2 (28.2 +/- 9.7 vs. 45.4 +/- 21.5 years, p < 0.01), and had the longer duration to initiate domiciliary oxygen therapy (43.0 +/- 10.9 vs. 25.3 +/- 20.3years, p<0.01). The former was also more likely to have lower % VC (p < 0.01), more elevated Pa(CO2) (p<0.05), and lower inspired flow rate of oxygen (p<0.01). There was no significant difference between the two groups with respect to BMI, FEV1/FVC, or CONCLUSION: Our investigation demonstrated that patients with sequelae of pulmonary tuberculosis under oxygen therapy revealed the different clinical course and characteristics regarding the presence or absence of previous surgical intervention.

Adult↗
PubMed2006

[High incidence of fatal cytokine-related disease among children with sequelae of perinatal hypoxic-ischemic encephalopathy].

Children with sequelae of perinatal hypoxic-ischemic encephalopathy (HIE) occasionally suffer from cytokine-related disease. We investigated 12 children with perinatal HIE sequelae, who died in childhood, concerning (1) the incidence of cytokine-related disease as the cause of death, and (2) the characteristics of the cytokine-related disease. Six (50%) of the 12 patients died from cytokine-related disease:two had virus-associated hemophagocytic syndrome (VAHS) ; one had acute encephalopathy;one had systemic inflammatory response syndrome (SIRS); and two had severe pneumonia/acute respiratory distress syndrome (ARDS). These six patients presented with increased liver transaminase, LDH, and CK, and decreased platelet count and albumin. This study shows the high incidence of cytokine-related disease as the cause of death in children with perinatal HIE sequelae. Further investigation is needed to clarify the pathogenesis of this disease.

Basal Ganglia Diseases↗
PubMedDate not supplied

[Neurological sequelae following electrocution. A case report and review of the literature].

INTRODUCTION: Electrocution is the cause of a large number of accidents and, of these, a considerable percentage result in death. Several factors affect the severity and distribution of the injuries. It is known that for low voltages the characteristics of alternating current make it three times more dangerous than continuous current. The high percentage of neurological sequelae can be accounted for by the fact that nerves are the tissue with the lowest resistance in the body and electricity tends to follow the path that offers the least resistance. CASE REPORT: A 16-year-old male who was accidentally electrocuted by an electric guitar and later suffered a cardiorespiratory arrest; the patient required intubation. After withdrawing sedation, the patient was found to be blind in both eyes and could not remember what had happened. FLAIR MR imaging revealed oedema in both occipital lobes and, to a lesser extent, in the junction between the parietooccipital and temporooccipital lobes. Treatment with steroids was established for three days. After approximately one month, the patient had recovered his sight and the brain injuries had disappeared. CONCLUSIONS: The neurological manifestations secondary to accidents caused by electricity are usually divided into two types -immediate and delayed. Blindness has rarely been reported as a sequela in those who have survived fulguration due to a lightning strike. The patient's recovery after administering treatment with steroids and the reversibility of the oedema could lead us to think that the mechanism producing this sequela was the damage to the nervous system caused directly by the electricity, which is known as the 'phenomenon of electroporation'.

Adolescent↗
PubMed1990

[Tuberculosis sequelae: pathophysiological aspect (ventilation)].

The percentage of the patients with PaCO2 more than 60 Torr and PaO2 more than 50 Torr were 13% in the patients with tuberculosis sequela (N = 502) and 4% in the patients with chronic obstructive lung disease (COLD, N = 727), who were treated with home oxygen therapy in the western region of Japan. Patients with chronic respiratory failure caused by tuberculosis sequela have higher PaCO2 than patients with COLD. Although the prognosis of patients with hypercapnia and moderate hypoxemia is not necessarily poor, some patients may need treatment for severe hypoventilation to prevent respiratory muscle fatigue and abnormal breathing during sleep. In this study, nine patients with hypercapnic chronic respiratory failure caused by tuberculosis sequela were ventilated by Chest Negative Pressure Ventilation (CNPV). The patients were monitored as in polysomnography by transcutaneous PCO2 (PtcCO2) electrode and Respiratory Inductance Plethysmography (RIP). Tidal volume induced by CNPV was larger during mouth breathing (504 +/- 128 ml, mean +/- s.d.) than during nose breathing (438 +/- 109 ml) calculated from RIP in awake state (N = 7). Oxygen saturation measured by ear oximeter and PtcCO2 were 94.4 +/- 2.9% and 57.8 +/- 12.2 Torr in awake state. Following CNPV SaO2 and PtcCO2 were 95.7 +/- 3.0%, 42.7 +/- 12.1 Torr in awake state (N = 9) and 93.0 +/- 4.4%, 57.0 +/- 15.7 Torr in Non-REM sleep (N = 5), respectively. CNPV is effective in these patients in awake state. During Non-REM sleep, CNPV maintains the PtcCO2 level only in awake state.

Aged↗
PubMed1990

[Tuberculosis sequelae: secondary bacterial infections].

Bacterial infections is one of the most important complications in the patients with pulmonary tuberculosis. We reported the causative microorganisms in these cases with special reference to various clinical features and presented the recommended treatment and prophylaxis against respiratory bacterial infections in the patients with pulmonary tuberculosis sequelae. In 1988 and 1989, 63 patients with tuberculosis sequela were demonstrated to have been infected with respiratory pathogenic bacteria by the quantitative sputum culture method (greater than or equal to 10(7)/ml) in Tokyo National Chest Hospital. The male/female ratio of these patients was 3.5, and their average age was 62.5 years. Causative microorganisms of the secondary infections in the patients with tuberculosis sequela were essentially similar in those with other lower respiratory tract infections, i.e., chronic bronchitis, bronchiectasis, diffuse panbonchiolitis, chronic pulmonary emphysema, etc. Pseudomonas aeruginosa, other glucose-nonfermentative Gram-negative bacilli (GNF-GNB), and glucose-fermentative Gram-negative bacilli (GF-GNB) were the major pathogenic bacteria responsible for the chronic respiratory failure and/or fatal outcome in the post-tuberculous patients. Patients with complications, including aspergillosis, atypical mycobacteriosis, bronchial asthma, and so forth, showed no specific causative microorganism for the secondary infections except frequent isolation of Haemophilus influenzae. Our clinical observations clearly demonstrated that there were differences between the causative microorganisms in patients hospitalized during 1988 to 1989 and those in patients without admission. Gram-negative bacilli, including P. aeruginosa, GNF-GNB and GF-GNB, and Staphylococcus aureus were predominant in hospitalized patients. On the contrary, Streptococcus pneumoniae, H. influenzae, and Branhamella catarrhalis were major pathogenic bacteria in patients without hospitalization.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1990

[Tuberculosis sequelae: home care of patients].

Home oxygen therapy (HOT) is important in the management of patients with chronic respiratory failure. I evaluated 159 HOT cases in our hospital during the period of 1988-1989. According to the national annual survey during the same period, HOT cases with tuberculosis sequelae were 46% of total national sanitorial HOT cases and 26-30% of all Japanese ones. Oxygen enrichers, especially molecular sieve type, became major methods of oxygen delivery (almost 90%) in both cases mentioned above. In our study, however, there were more patients with tuberculosis sequelae (66%), and more oxygen cylinder users (40%). Portable oxygen supply was higher in our HOT cases, especially in patients with tuberculosis sequelae or chronic pulmonary emphysema, and in users of oxygen cylinders or liquid oxygen. By questionnaire, we confirmed the earnest desire by the patients for the lighter and long lasting portable oxygen supply system.

Chronic Disease↗
PubMedDate not supplied

[Neuropsychologic and clinical effects of protirelin tartrate in patients with stroke sequelae].

An ischemic cerebral lesion involves a progressive metabolic damage to neurons and neurotransmitter alterations. The consequent functional deficits give rise to the neurological and cognitive impairment seen in most stroke patients. As soon as neuronal loss brings synaptic activities to an end, a maximum release of neurotransmitters and peptides occurs, no longer balanced by effective synthesis activity. This unbalanced control of neurotransmitters causes the typical neurological and psychological disturbances of the post-stroke phase. In particular, the unbalance of the catecholaminergic and/or serotoninergic system seems to be related to emotional disturbances, whereas the cholinergic unbalance seems to be the cause of cognitive impairment (which is manifested in memory and learning capacity deficits). The recent demonstration that peptides also act as synaptic transmission modulators supplied the rationale to propose the use of neuropeptides as a substitutive therapy in many neurodegenerative pathologies and particularly in post-traumatic encephalopathies and stroke sequelae. Furthermore, one of these neuropeptides, protirelin, has been proved to have neurotransmitter and neuromodulator activities as well as being capable of inducing the functional maturity and regeneration of neurons and improving functional recovery and vigilance in cases of stroke sequelae. A double-blind multicenter trial versus placebo was therefore performed to evaluate the efficacy and tolerability of protirelin tartrate (TRH-T) in this pathology. The neuropsychological functions (attentiveness, learning capacity, memory) were evaluated in 136 patients with stroke sequelae, treated with TRH-T or with placebo.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1990

[Prognostic factors of neurosensory sequelae in extremely premature infants].

Modern neonatal intensive care has led to a rise in the survival rate of very low birthweight infants (VLBW), but at the same time is a greater number of neurosensorial sequelae. In this study, 50 VLBW (weight less than 1,500 g) babies followed up for at least 12 months are analysed. 18% showed major sequelae (40% of those weighing less than 1,000 g, 12.5% of those weighing 1,000 g or more). The prognostic factors which were most important in the prediction of sequelae were: low birthweight, major irregularities in the EEG, the presence of sepsis, and prolonged ventilotherapy or antibiotherapy.

Brain Diseases↗
PubMed1989

[A electromyographical observation on the treatment of poliomyelitis sequelae with series electroacupuncture].

We observed the changes of quadriceps femoris EMG before and after treatment on treatment 41 cases of poliomyelitis sequelae with series electroacupuncture. In 41 patients muscles strength of quadriceps femoris before treatment in 35 cases was below 0 degree and 1 degree. The changes of EMG, Most had no motor unit potential, some only a few but duration was long, and amplitude decreased markedly. A few had fibrillation or positive sharp wave. The changes in EMG accorded with the diagnosis of poliomyelitis sequelae. After 3 month treatment, tee EMG findings were decreasing or there was loss of fibrillation, appearance of motor unit potentials, increase of the amount of motor unit potentials, prolongation of duration and increasing of amplitude of motor unit potentials, appearance of polyphasic potentials etc. Through analysis of EMG, 32 among 41 cases were improved, effective rate was 78%, P less than 0.01. EMG indices indicate the efficacy of series mg electroacupuncture in treating the sequelae of poliomyelitis and confirm the clinical therapeutic effect of the treatment. The indices indicate that the pathological changes of damaged anterior horn cells of the spinal cord were decreased and partial recovery of nervous function. The EMG changes paralleled those in clinical therapeutic effect of treatment and changes of muscle strength.

Acupuncture Therapy↗