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Periodontal treatment decisions for molars: an analysis of influencing factors and long-term outcome.

BACKGROUND: The purpose of this retrospective study was 1) to analyze factors influencing the treatment decision for periodontitis-affected molars and 2) to evaluate the long-term outcome of the decision. The treatment alternatives included in the analysis were maintenance of the tooth with only non-surgically/surgically performed scaling/root planing with or without furcation plasty, root separation/resection, and tooth extraction. METHODS: Data collected from a total of 1,313 first and second molars in 222 patients (mean age 45 years; range 14 to 73 years), referred for periodontal treatment, were analyzed with respect to treatment decisions for furcation-involved teeth. The patients had been examined with respect to oral hygiene status, gingival conditions, probing depth, furcation involvement, and radiographic bone height before and after active periodontal treatment. Frequencies, mean values and standard deviations were calculated for the various variables assessed. Multiple regression models were formulated in order to analyze the influence of various variables on treatment decisions. One-hundred and sixty (72%) of the patients agreed to participate in a follow-up examination to determine the clinical and radiographic status of the molars 8 to 12 years after the active phase of treatment for evaluation of the long-term outcome of the treatment decision. RESULTS: Twenty-eight percent of the molars were extracted and 4% were root separated/resected. Factors found to significantly influence the decision of tooth extraction were tooth mobility, tooth position, lack of occlusal antagonism, degree of furcation involvement, and remaining bone support. Of the factors analyzed with respect to root separation/resection, molar position and degree of furcation involvement showed the strongest influence on the treatment decision. The 8- to 12-year follow-up examination revealed that 96% of the molars subjected to non-resective therapy were still in function. The corresponding figure for root separated/resected molars was 89%. Loss of radiographic bone support during the 10-year follow-up period was 0.1 to 0.6 mm for the various molars with the highest value for maxillary second molars. CONCLUSIONS: A conservative approach to the treatment of molars with even deep furcation invasions may show a high long-term success rate, provided maintenance care is offered.

Adolescent↗

Does osteomalacia contribute to development of oral complications of oxalosis?

Two renal dialysis patients with oral manifestations of oxalosis had undecalcified sections of iliac and alveolar bone and teeth examined histologically in an attempt to explain the development of tooth mobility and tooth loss. Osteomalacia was detected in all bone specimens and attributed to aluminum toxicity after the histochemical localization of aluminum at the calcification front between osteoid and calcified matrix. Aluminum was also detected histochemically in the cementum of teeth. Calcium oxalate crystals were present in bone marrow, teeth, and gingiva. It is proposed that tooth mobility and tooth loss in oxalosis result from the combined effects of osteomalacia and oxalate crystal deposition within the periodontium. To prevent avoidable tooth loss it is suggested that patients with oxalosis who develop tooth mobility should have aluminum toxicity and osteomalacia excluded as causal factors.

Adolescent↗

Effects of sympathetic nerve activity on acute mobility of the rabbit incisor tooth.

The contribution of local blood flow to the buffering properties of the periodontal ligament was examined in 15 anesthetized rabbits. The position of the tooth was recorded by an ultrasonic transit time technique, and local vascular pressures and volumes were altered by electrical stimulation of the cervical sympathetic nerves. The unloaded tooth was shifted into a slightly intruded position by nerve stimulation, and from this position, intrusion movements evoked by 5- to 10-g loads were found to be 10-15% smaller than before the stimulation. Tooth mobility was unaffected by 20-30 mm Hg reductions in mean arterial pressure, but similar decreases in mobility as evoked by nerve stimulation were observed when the pressure was brought down to 10-25 mm Hg. This procedure also produced about the same intrusive shift of the unloaded tooth. Most likely, the sympathetic nerve activity decreased tooth mobility by causing a fall in periodontal vascular pressures, thereby moving the tooth into a position where it was more resistant to further, load-induced intrusion.

Animals↗

Orthodontic and surgical intervention to arrest tooth loss secondary to subgingival elastic.

Elastic bonds used for orthodontic tooth movement without benefit of attached mechanisms have been shown to migrate apically, causing severe periodontal damage and eventual tooth mobility and tooth loss. The literature indicates high mortality rates for such involved teeth. A case report is presented, illustrating initial successful retention of teeth following surgical removal of a displaced elastic band. Cooperation between oral surgeon, periodontist, and orthodontist, in conjunction with high standards of oral hygiene by the patient, may lead to successful retention of otherwise condemned teeth. It is also suggested that elastic band therapy be carefully supervised when used to move teeth without controlling attachment mechanisms.

Alveoloplasty↗

Favorable periodontal regenerative outcomes from teeth with presurgical mobility: a retrospective study.

BACKGROUND: The relevance of tooth mobility on periodontal healing is still controversial. The purpose of the present study was to evaluate the effect of presurgical tooth mobility on periodontal regenerative outcomes. METHODS: The data in this study were derived from three randomized clinical trials which evaluated regenerative procedures. Sixty-four patients with one intraosseous periodontal defect each received one of the following treatments: guided tissue regeneration (GTR) using expanded polytetrafluoroethylene (ePTFE), GTR using a bioabsorbable membrane with or without demineralized freeze-dried bone allograft (DFDBA), or enamel matrix derivative with or without DFDBA. Probing depth (PD), clinical attachment level (CAL), recession (REC), and tooth mobility (TM) were recorded at baseline and 1 year after treatment by a calibrated examiner. The post-surgical follow-up and maintenance periods were designed to optimize plaque control. The teeth were grouped according to their baseline Miller index TM score. The grouping yielded 36 teeth with minimal mobility, score 0; 13 teeth with score 1; and 15 with score 2. The mean changes in PD, CAL and REC from baseline to 1 year were calculated for each group. One-way analysis of variance (ANOVA) was performed to assess differences between the tooth mobility groups considering changes in PD, CAL, and REC at 1 year. RESULTS: The mean PD reduction from baseline to 1 year for teeth with TM score 0 was 3.67 mm; for TM score 1, 2.81 mm; and for score 2, 3.73 mm. The corresponding values for the gain in CAL were 2.73, 1.96, and 2.36 mm, respectively. According to ANOVA, the probing depth reductions and clinical attachment level gains found in each group were not statistically different, P= 0.218 and P= 0.252, respectively. CONCLUSION: Within the limitations of this analysis, it can be concluded that interproximal, intraosseous defects of teeth with limited presurgical tooth mobility; i.e., teeth with Miller's Class 1 and 2 mobility, will respond favorably to regenerative therapy.

Adult↗

Oral-dental findings in a case of Maffucci's syndrome.

A case of Maffucci's syndrome (MS) in a 17-year-old Caucasian female is presented with a thorough intraoral examination. The prominent finding was recurrent gingival hyperplasia affecting both the free and attached gingiva with deep periodontal pockets, tooth mobility, pathological tooth migration, and severe alveolar bone loss. Furthermore, the pattern of alveolar bone destruction, in many ways, resembled that of localized juvenile periodontitis. Although there is always the possibility that these oral features may not be related with the syndrome, we suggest a careful dental and periodontal examination in future cases, which we believe will help develop a better description of oral findings in MS.

Adolescent↗

Periodontal microbiota of mobile and non-mobile teeth.

The mechanism of accelerated periodontal destruction around teeth with occlusal trauma and increased mobility remains unclear. One possibility is that tooth mobility creates a subgingival environment conducive to overgrowth by periodontal pathogens. This study compared the subgingival microflora in mobile and non-mobile teeth of 35 adults on supportive maintenance therapy and 15 with untreated adult periodontitis. In each subject, subgingival paper-point samples were obtained from a mobile tooth with a probing depth of 4 mm or greater and from a non-mobile tooth with similar probing depth and gingival index. Samples were transported in VMGA III medium. Pockets around mobile teeth harbored significantly higher proportions of Campylobacter rectus (P = 0.001) and Peptostreptococcus micros (P = 0.05) than pockets with non-mobile teeth. Mobile teeth also tended to show elevated levels of Porphyromonas gingivalis, but this did not reach statistical significance. This study suggests that tooth mobility may constitute a risk for periodontal breakdown due to an increased subgingival occurrence of specific periodontopathogens. This hypothesis needs to be verified in longitudinal clinical and microbiological studies.

Adult↗

[Maintenance and the clinical evaluation of periodontal patients in Konus-Telescope denture].

In order to assess by periodontal evaluation the changes that might occur with time in the abutment teeth and periodontal tissues when Konus-Telescope dentures are used as that final treatment of periodontal disease, the dentures (15 units) were placed in 13 patients with missing tooth and periodontal disease and findings at the time of denture placement and 30 months after the placement were compared. The number of cases that exhibited significant changes in hygiene level, tissue inflammation and periodontal pocket depth of the abutment teeth after 30 months was very small, while as many as 85.2% of the abutment teeth showed decrease in tooth mobility. Increase in tooth mobility was not detected in any of the cases. In addition, X-ray examination revealed tendencies toward improvement of the periodontal ligament and remission of alveolar bone resorption in many of the cases. These results suggest that Konus-Telescope denture is highly offers protection of the residual periodontal tissues through its secondary splint action.

Bone Resorption↗

The relative importance of plaque and occlusion in periodontal disease.

A series of studies has investigated interactions between periodontal trauma and marginal periodontitis in relation to the initiation, progression and treatment of periodontal disease. Lesions of trauma in the periodontal ligament do not initiate the loss of connective tissue attachment characteristic of marginal periodontitis. Studies conducted in squirrel monkeys and beagle dogs in which jiggling forces were superimposed upon an established marginal periodontitis reported increased loss of alveolar bone, but the accelerated loss of attachment which occurred in the dog model did not occur in the monkey model. In order to clarify the relative importance of inflammation and tooth mobility in the treatment of advanced periodontal disease, periodontal responses were evaluated after removing combinations of traumatic and inflammatory components. Elimination of trauma in the presence of existing marginal inflammation did not reduce tooth mobility or increase bone volume. Osseous regeneration and decreased tooth mobility occurred after resolving both components; however, similar findings occurred after resolving inflammation in the presence of continued tooth mobility. After resolution of inflammation, remaining tooth mobility does not result in increased loss of connective tissue attachment. On a clinical level for periodontal disease treatment, the findings place decreased emphasis upon management of tooth mobility and increased emphasis upon resolution of marginal inflammation.

Animals↗

Relative contribution of patient-, tooth-, and site-associated variability on the clinical outcomes of subgingival debridement. I. Probing depths.

BACKGROUND: The objective of this clinical trial was to assess the relative contribution of patient-, tooth-, and site-associated variables on changes in probing depths (PD) following delivery of a standard non-surgical phase of periodontal therapy. METHODS: Ninety-four (94) systemically healthy subjects with severe generalized periodontitis were included in this 6-month prospective longitudinal study. Medical, periodontal, and microbiological parameters were collected at baseline and 2 and 6 months after completion of oral hygiene instructions, motivation, and subgingival debridement using a piezoelectric instrument. The relative contribution of patient-, tooth-, and site-associated variables was evaluated with a hierarchical multilevel analysis. RESULTS: Eighty percent (80%) of variability in PD reductions was attributed to site level parameters, while 12% was at the tooth level and 8% at the patient level. The multilevel analysis associated PD reductions with patient factors (cigarette smoking status and carriage of the rare allele of a specific polymorphism for the interleukin-6 [IL-6] gene), tooth factors (tooth mobility and tooth type), and site factors (mesial and distal location). Cigarette smoking and carriage of the rare allele of the IL- 6-174 G/C polymorphism were associated with less PD reduction. Incisors and canines responded better than premolars and molars. A dose-dependent effect of mobility was observed: teeth with higher baseline mobility resulted in significantly greater decreases in PD. At the site level, greater reductions were observed at interdental sites (compared to facial or oral), and at deeper sites (1.2 mm for 4 to 5 mm pockets and 2.4 mm for pockets > or =6 mm). CONCLUSION: These data provided an estimation of the relative contribution of site-, tooth-, and patient-associated variables in terms of PD reductions following a standard course of machine-driven subgingival debridement.

Cytosine↗

Periodontal ligament tissue reactions to trauma and gingival inflammation. An experimental study in the beagle dog.

The aims of the present study were to analyze (i) which tissue changes may occur in the zone of co-destruction to better understand why trauma from occlusion may induce additional attachment loss, and (ii) whether changes occur in the periodontal ligament tissue when an inflammatory lesion (ICT) approaches the periodontal ligament space. 16, 1-year-old beagle dogs, were selected and divided into 2 groups, group A and group B, consisting of 6 and 10 dogs, respectively. In group A, on day 0, a bucco-lingual jiggling type movement was induced resulting in increasing tooth mobility at P3 (test tooth) by the application of an orthodontic elastic which traversed the buccal surface of the crown of the test tooth. The elastic was exchanged either in a buccal or in a lingual position 2x a week during a 3-month period. 3P served as non-jiggled control tooth. Tooth mobility measurements were recorded on days 0, 30, 60, 90. A plaque control regimen was maintained until the end of the experiment (day 90). On day 90, biopsies including P3 and 3P were harvested. The dogs representing group B, were divided into 2 subgroups of 5 each, group BI and group BII. On day 0, a 4-month period of experimental periodontal tissue breakdown was initiated by placing cotton floss ligatures submarginally around the mandibular fourth premolars (4P4) in group BI and around the mandibular third premolars GP3) in group BII. All ligatures were exchanged, replaced 1x every month, and on day 120 permanently removed. On the same day, biopsies included 4P4 were harvested. Following supragingival debridement 3P3 were allowed to accumulate plaque until the end of the study (day 225). On this occasion, biopsies including 3P3 were harvested. The results of the histological measurements revealed that in the most coronal portion of the periodontal ligament of teeth exhibiting increasing mobility, there was an increased width, a reduced % tissue volume of collagen, and an increased volume of vascular structures and leukocytes. Furthermore, the number of osteoclasts bordering this portion of the alveolar bone was increased and the number of collagen fibers inserting into the root cementum and into the alveolar bone was reduced. It was also demonstrated that in teeth with normal mobility, the position of the gingival ICT failed to influence the composition of the tissue within the coronal portion of the periodontal ligament.

Alveolar Process↗

Influence of occlusal adjustment by grinding on gingivitis and mobility of traumatized teeth.

The effect on marginal inflammation and tooth mobility of occlusal adjustment by grinding was investigated in 43 occlusally traumatized teeth in 29 subjects with gingivitis and marginal periodontitis. The material consisted of 4 groups with tooth mobility of varying degrees of severity, and bone destruction. In all groups increased tooth mobility decreased subsequent to occlusal adjustment. The latter was without effect on the sulcus fluid flow rate or gingivitis scores in either gingivitis or periodontitis patients.

Adolescent↗

Probing pocket depth at mobile/nonmobile teeth.

The aim of the present investigation was to study the influence of an increased tooth mobility on the resistance offered by the periodontal tissues to probing. 6 beagle dogs were used. At the start of the experiment, the animals had clean teeth and normal gingival and periodontal conditions. In each dog, a device was installed in the lower left jaw quadrant to expose the third premolar (P3) to jiggling forces which would enhance the mobility of this "test" tooth. The contralateral tooth served as the non-jiggled control. During the 3 months of experimentation, the teeth of the dogs were cleaned on a regular basis. Clinical examinations including tooth mobility measurements were performed on days 0 and 90. After the examination on Day 90, a probe was inserted in the buccal "pocket" of the mesial root of 3P and P3. The probe was retained with composite. Biopsies including the test or control tooth with adjacent buccal periodontal tissues were harvested, fixed and decalcified. Each biopsy was divided in one mesial and one distal portion (root). The distal portion was embedded in Epon, sectioned and stained in PAS and toluidine blue, while the mesial portion, following probe removal was embedded in paraffin, sectioned and stained in hematoxylin-eosin. The sections were exposed to histometric and morphometric measurements. The findings demonstrated that tissue alterations which occur at mobile teeth may reduce the resistance offered by the periodontal tissues to clinical probing. Such alterations include (i) reduced height of the alveolar bone, (ii) reduced amount of collagen, and increased vascularity in the enlarged supracrestal connective tissue.

Animals↗

The effect of splinting of teeth in combination with reconstructive periodontal surgery in humans.

The purpose of this study was to evaluate the effect of splinting teeth on the results of periodontal reconstructive surgery using a specific carbonate bone replacement graft (BRG) material. Forty-five patients were randomly treated with a periodontal surgery approach. Natural coral calcium BRG was utilised in 33 patients. This 33-patient group was divided into three equal groups. In the presplint group, teeth were splinted to at least two rigid teeth before surgery, in the postsplint group, teeth were splinted at suture removal, and in the nonsplint group, the treated teeth were not splinted at all. In 12 patients, teeth were treated with surgical debridement (DEBR) alone and not splinted. Periodontal probing depth (PPD), clinical probing attachment level (CPAL), and tooth mobility were measured using desmodontometry (DDM) and periotest (PTV) with reproducible methods before surgery and at various periods up to 1 year afterwards. A decrease in PPD (5.4 mm, SD 1.4 mm) and tooth mobility (DDM-horizontal 257 microns, SD 60 microns) and a gain of CPAL (5.1 mm, SD 1.4 mm) were seen following the use of BRG in presplint teeth. In the same group, PPD and tooth mobility were significantly reduced compared to nonsplint teeth. DEBR alone showed reductions in tooth mobility and PPD and a significantly smaller gain in CPAL than in presplint teeth treated with BRG. The less favourable improvement in periodontal function of postsplint or nonsplint teeth seemed to be due to the loss of BRG material caused by tooth mobility. These results indicate that an undisturbed wound healing process using BRG together with tooth stability is beneficial to overall clinical success.

Alveolar Bone Loss↗

Resolution of furcation bone loss after non-surgical root canal treatment: application of a peptidase-detection kit for treatment of type I endoperiodontal lesion.

Here, we report the management of a type I endoperiodontal lesion with furcation bone loss. A 59-year-old female attended our hospital with the chief complaint of mobility of tooth 46 and recurrent gingival swelling around the tooth. She previously received dental treatment from two dentists, but her condition did not improve. The tooth manifested the symptoms of typical periodontitis, such as gingival swelling, tooth mobility, pus discharge from the periodontal pocket and furcation bone loss. The tooth had no caries and the pulp reacted to an electric pulp test. Careful examination of the gingiva revealed traces of dental fistula. X-ray examination via a gutta percha inserted into the fistula revealed that furcation bone loss was associated with the periapical lesion. We diagnosed a type I endoperiodontal lesion, and applied Periocheck, a detection kit for peptidase-producing bacteria, to check for decreases in bacteria in the furcation and root canals. Soon after non-surgical root canal treatment, the condition of tooth 46 improved without periodontal treatment. After confirming a negative score with Periocheck, the root canal was filled. After 3 months, the furcation bone loss was on the way to recovery. These results indicate that proper diagnosis and confirmation of a decrease in root canal bacteria are important for treating endoperiodontal lesions.

Alveolar Bone Loss↗