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Retinal telangiectasias associated with longstanding retinal detachment as a prognostic sign.

The authors present 26 cases (28 eyes) of rhegmatogenous retinal detachment, lasting more than 6 months, in which retinal telangiectasias appear in the periphery of the retina as a secondary phenomena, seemingly related to hypoxic factors. A comparison is made with a control group of 25 cases of longstanding retinal detachment taken at random in order to establish statistical differences. Considerations regarding their pathogenesis and their value as a prognostic sign are made.

Adolescent↗

[Microangiopathy and retinal dystrophy].

Two cases are described of an association of retinal dystrophy and a vasculopathy similar to Coat's disease. The first case was a female adult in whom the two sets of symptoms appeared almost simultaneously. In the second case the disease appeared in infancy, evolved rapidly during adolescence and led to blindness. In both cases, the vasculopathy developed over several years and then stabilised; in contrast, the dystrophy, which was of the paucipigmentary type, continued to get worse. From these two cases, and others described in the literature, it appears that many causes can be involved in the association of the two syndromes. A genetic factor that has been demonstrated in several families was not present in these two patients; there appears to have been an immunological or inflammatory process, not yet identified, that became active at the time of the rapid evolution of the dystrophy.

Adolescent↗

[Coats' disease: early detection and early treatment (author's transl)].

With regard to visual prognosis Coats disease can grossly be divided in 3 different stages: If the disease is confined to the periphery of the fundus, complete recovery can be achieved by appropriate treatment. If there is already a severe macular involvement central visual acuity hardly improves, but blindness can be prevented. In case of a widespread, exsudative retinal detachment, the prognosis is unfavourable. Early diagnosis and early treatment of Coats' disease are therefore very important.

Adolescent↗

Alport's syndrome and retinal telangiectasia.

A 30-year-old woman with Alport's syndrome was noted to have unilateral retinal telangiectasia. Intravenous fluorescein angiography was performed to help establish the diagnosis. Photocoagulation was not done since visual acuity was good and there was no apparent threat at this time to central vision. To our knowledge, this is the first reported association of retinal telangiectasia with Alport's syndrome.

Adult↗

Spontaneous regression of retinal lesions in Coats' disease.

Coats' disease is characterized by vascular anomalies in the retina that are usually associated with exudates. In the absence of treatment the disease almost always progresses toward loss of vision and, often, loss of the eye. This report describes three patients in whom some of the retinal lesions apparently regressed spontaneously; only two other such patients are mentioned in the literature. These patients may have had a form of Coats' disease that has a better prognosis than usual for the eye.

Adolescent↗