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PubMed1980

Vocal cues as indices of schizophrenia.

The hypothesis that schizophrenic patients can be differentiated from non-schizophrenic patients was tested. In addition, the impressions about personality characteristics conveyed by voice quality were explored. Ten schizophrenics and ten non-schizophrenic patients, all from a State Hospital, were recorded individually as they read the same passage. Five judges listened to randomized recordings and completed a questionnaire on each speaker to indicate whether the subject was schizophrenic, to rate the degree of the subject's psychopathology, to rate vocal behavior with a Voice Characteristics Sale made up of six adjectives, and to rate vocal indices of personality disorder with a Voice Psychopathology Scale made up of 26 adjectives describing pathological personality characteristics. The schizophrenics were distinguished from non-schizophrenics on the basis of voice quality. The schizophrenic patients were seen as more inefficient, despondent, and moody. Information conveyed by speakers' voices was explored by a factor analytic technique. Four factors, general disintegration, dysphoria, social distance, and agitation, were identified.

Adolescent↗
PubMed1998

Prospective follow-up study of borderline personality disorder: prognosis, prediction of outcome, and Axis II comorbidity.

OBJECTIVE: To examine the rate of persistence of borderline personality disorder (BPD), the existence of concomitant personality disorders on follow-up, and the predictors of outcome in patients who met criteria for BPD compared with patients with borderline features who failed to meet all of the criteria. METHOD: This prospective cohort study reassessed subjects for BPD diagnosis and cooccurring personality pathology at 7 years follow-up. Initial measures of borderline and comorbid personality psychopathology were used to predict levels of borderline or other personality disorder psychopathology at follow-up. RESULTS: Of the 57 subjects who initially met the criteria for BPD, 30 (52.6%) were found to have remitted BPD, and 27 (47.4%) were characterized as having persistent BPD. The remitted group met significantly fewer comorbid personality disorder diagnoses than the persistent group (mean = 0.8, mean = 3.5 respectively; P < 0.05). Results also indicated that the initial level of borderline psychopathology was predictive of borderline psychopathology at follow-up, which explained 17% of the variance. CONCLUSIONS: This prospective follow-up study found that almost 50% of former inpatients with BPD continue to test positive for BPD at 7 years follow-up, and these persistent BPD patients also had significantly more comorbid personality psychopathology. Borderline psychopathology at follow-up was primarily predicted by the level of borderline psychopathology recorded at the initial assessment.

Adult↗
PubMed2005

Principal components analyses of the MMPI-2 PSY-5 scales: identification of facet subscales.

The Personality Psychopathology Five (PSY-5) is a five-factor personality trait model designed for assessing personality pathology using quantitative dimensions. Harkness, McNulty, and Ben-Porath developed Minnesota Multiphasic Personality Inventory-2 (MMPI-2) scales based on the PSY-5 model, and these scales were recently added to the standard MMPI-2 profile. Although the PSY-5 constructs are multidimensional in definition, explicit subscales for the broader PSY-5 scales have not been developed. The primary goals of this study were to empirically derive subscales for the MMPI-2 PSY-5 scales using principal components analysis (PCA) and to replicate these subscales with an independent sample. Individual PSY-5 scales were analyzed using PCA with an initial sample of 4,325 MMPI-2 protocols, and the component structure was replicated with a second sample of 4,277 MMPI-2 protocols. A third sample of 4,327 protocols was used to further evaluate the internal consistency reliabilities of the resulting facet subscales. Overall, replicable facet subscales were identified with content areas that are largely congruent with Harkness and McNulty's model.

Adult↗
PubMed2001

Sexual trauma and personality: developmental vulnerability and additive effects.

Two types of sexual trauma, sexual abuse in childhood and rape in adulthood, were investigated in terms of possible effects on personality. Four groups of participants were studied: women who had experienced sexual abuse in childhood, women who had experienced rape as adults, women who had experienced both of these sexual traumas, and a control group of women who had experienced no sexual trauma. Personality functioning was assessed using the Dimensional Assessment of Personality Pathology. Groups who had experienced childhood sexual abuse displayed the highest degree of personality disturbance; however, the additive effects of repeated sexual trauma were limited. These findings may reflect the outcome of specific adversity in childhood on the psychobiological constructs underlying personality.

Adult↗
PubMed1985

Stability of the personality and symptom scales of the Millon Clinical Multiaxial Inventory.

This study examines the stability of the basic and pathological personality and symptom scales of the Millon Clinical Multiaxial Inventory (MCMI) in three clinical samples. Consistent with the theory upon which the MCMI is based, higher stability estimates were found among basic personality scales in comparison with symptom scales. However, stability estimates which included initial MCMI administrations at intake into treatment were generally lower than those based upon administrations which occurred later in the treatment process. This later finding suggests the need to consider timing of administration when interpreting the MCMI.

Humans↗
PubMed2005

The natural history of conduct disorder symptoms in female inmates: on the predictive utility of the syndrome in severely antisocial women.

This study examined the utility of the conduct disorder (CD) diagnosis in predicting antisocial personality disorder (ASPD) among incarcerated women. It was surprising that most female inmates did not meet standard criteria for ASPD. This was due to a low occurrence of CD symptoms reported before age 15. Cluster analysis of CD symptoms revealed 4 types that characterized women with criminal histories. One type, which was characterized by a history of CD with interpersonal and physical aggression, was more predictive of ASPD than the traditional CD diagnosis. Yet another type, characterized by destruction of property, also represented an improvement over the traditional CD diagnosis. Overall, the results suggest that the types of CD behaviors, rather than their number, may be a more important indicator for identifying women at risk for future antisocial personality pathology.

Adult↗
PubMed1998

Dependency in the personality disorders: intensity, insight, expression, and defense.

Although dependency-related dynamics play a role in many forms of personality pathology, a review of the literature in this area reveals that individuals with different personality disorders differ with respect to the intensity of underlying dependency needs, their degree of insight regarding these needs, the ways in which dependency needs are expressed in important interpersonal relationships, and characteristic defenses used to modulate underlying dependency needs. Clinical, theoretical, and empirical implications of these findings are discussed, and suggestions for future research on the dependency-personality disorders relationship are offered.

Adult↗
PubMedDate not supplied

[Biological markers in schizotypal and borderline personality disorders].

A preliminary but growing body of evidence supports the existence of biological substrates in personality disorders. Based on a review of the literature, the article deals with the major biological markers: genetic, cognitive, biochemical, electrophysiological and organic markers, of schizotypal and borderline personality disorders. In addition, the article compares these findings in these two types of pathological personality. In the field of genetics, we notice several indices in favour of a relationship between schizotypal personality disorder (SPD) and chronic schizophrenia. In contrast, in borderline personality disorder (BPD), indices were lacking for such a relationship between this disorder and one of the axis I diagnosis, or a clear genetic transmission. In the field of cognitive tests, we can note in both SPD and BPD, that the abnormalities which would be at the level of temporal and frontal lobes, may be implicated in the observable cognitive troubles in these two disorders. In the field of neurobiochemistry, the dopaminergic and serotonergic systems seem to be implicated in the etiology of SPD while several data point out the fact that several neurotransmitter systems (dopaminergic, serotonergic, noradrenergic and cholinergic) seem to be involved in the etiology of BPD. Finally, in the field of electrophysiology, we notice that some of these tests observed in SPD (smooth pursuit eye movements, evoked potentials, modification of the electrodermic response) seem reinforcing the relationship between SPD and schizophrenia while those observed in BPD seem reinforcing either a relationship between BPD and depression (sleep studies), or a relationship between BPD and schizophrenia (evoked potentials, smooth pursuit eye movements).

Biomarkers↗
PubMed1990

Psychological test characteristics of depressed and panic patients.

This study compared the psychological test performance of patients with major depression (MD) (n = 23), patients with panic disorder (PD) (n = 20), and normal subjects (n = 24). Results indicated that scores of normal subjects were significantly less pathological than those of both patient groups on almost all psychological test scales, but that the test performance of the two patient groups did not differ. The only difference between the two patient groups was on the level of self-reported and observer-rated depression. Both patient groups exhibited significant personality pathology, and the rate of personality disorders diagnosed by the Millon Clinical Multiaxial Inventory (MCMI) (base rate greater than 84) was 73% for PD patients and 86% for MD patients. The problems of assessing personality during episodes of MD and PD and the possible overdiagnosis of personality disorders by the MCMI are discussed.

Adult↗
PubMed1996

Axis II diagnoses and treatment refractoriness in schizophrenia.

In a previous medical record review study we identified a subset of chronic schizophrenic patients with comorbid Axis II personality disorder diagnoses, who had significantly longer lengths of inpatient stay as compared to schizophrenic patients without Axis II diagnoses. This study describes a detailed review of a subset of these records. Eighteen records of schizophrenic patients with comorbid Axis II diagnoses were matched with records of patients without comorbid diagnoses. Demographic and premorbid data revealed no differences between the groups, indicating that the Axis II diagnoses were markers for current as opposed to past psychopathology. Negative symptoms were lower in the cohort with comorbid Axis II personality disorder diagnoses on admission only, while affective symptomatology was increased in this group throughout treatment. Ratings of personality pathology showed a trend towards significance, with the comorbid group demonstrating greater amounts of maladaptive personality traits. These data support the notion that personality traits may be independent of Axis I symptomatology in chronic schizophrenia, and can influence the course of treatment.

Adult↗
PubMedDate not supplied

Personality dimensions in the chronic fatigue syndrome: a comparison with multiple sclerosis and depression.

This study investigated the relative rates of personality disturbance in chronic fatigue syndrome (CFS). Individuals who met the CDC criteria for CFS were compared to two other fatiguing illness groups, mild multiple sclerosis and depression, as well as sedentary healthy controls. Subjects were administered a structured psychiatric interview to determine Axis I psychiatric disorders and two self-report instruments to assess Axis II personality disorders and the personality trait of neuroticism. The depressed group had significantly more personality disorders and elevated neuroticism scores compared with the other three groups. The CFS and MS subjects had intermediary personality scores which were significantly higher than healthy controls. The CFS group with concurrent depressive disorder (34% of the CFS group) was found to account for most of the personality pathology in the CFS sample. The results are discussed in the context of the relationship between personality variables and fatiguing illness.

Adaptation, Psychological↗
PubMed1990

The effect of personality on placebo response in panic patients.

Twenty-eight patients who participated as a placebo group in a treatment study of panic disorder were studied to determine the effect of personality on study completion and outcome. Those subjects who completed only 3 weeks had significantly more pathological personality traits than those who continued in the study. For those continuing beyond 3 weeks, there were negative correlations between the paranoid and borderline personality traits and a global outcome measure. Spontaneous panic attacks were not affected by personality.

Adult↗
PubMed1998

Validation of the self-report questionnaire DIP-Q in diagnosing DSM-IV personality disorders: a comparison of three psychiatric samples.

The DSM-IV section of the DSM-IV and ICD-10 Personality Questionnaire (DIP-Q) was used to screen for personality disorders in 448 subjects from three clinical samples (general and forensic psychiatric patients and candidates for psychotherapy) and a sample of 139 healthy volunteers. Differences between the samples with regard to patterns of personality pathology in relation to concurrent Axis I disorders and sociodemographic variables were analysed. The prevalence of personality disorders according to DIP-Q was 14% among the healthy volunteers, compared to 59% in the general psychiatric sample, 68% in the forensic psychiatric sample and up to 90% among psychotherapy candidates. Moreover, from a dimensional perspective (i.e. the number of fulfilled Axis II criteria), all clinical groups differed significantly from the control group in all specified personality dimensions and clusters. Dimensional DIP-Q cluster scores also discriminated significantly between the three clinical samples. Unexpectedly, the odds ratio for an Axis II disorder was nearly five times higher among psychotherapy applicants than among general psychiatric patients, independent of concomitant Axis I disorders, gender or age. The strongest association between DIP-Q score and Axis I disorders was found for depressive disorders, which more than doubled the odds ratio for a personality disorder diagnosis. This association could result from high true comorbidity, but could also be due to the fact that a concomitant depressive state can increase self-reported personality difficulties. The high prevalence among psychotherapy candidates may to some extent reflect help-seeking exaggeration of problems. These are aspects to consider when using the DIP-Q, which overall appears to discriminate well between different samples.

Adolescent↗
PubMed2000

Genetic structure of the five-factor model of personality in a Japanese twin population.

Dimensional approaches have been used to describe the fundamental dimensions that underlie the entire domain of normal and pathological personality. We tested the five factor model of personality structure in a sample of Japanese twins, to clarify the contributions of genetic and environment. The revised NEO personality inventory (NEO-PI-R) was administered to 251 twin pairs, ranging in age from 15 to 27 years of age. The NEO-PI-R is a 240-item questionnaire which was developed to assess the dimensions of personality. Univariate genetic analysis showed that the AE model in which phenotypic covariances are explained only by additive genetic (A) and nonshared environment (E) is still a plausible model, and that the relative proportion of genetic influence was comparable to that reported by Loehlin (1992). Multivariate genetic analysis of the Japanese data suggested/revealed that the five factors are genetically dependent on each other and one common genetic factor mediates their interdependence. Previous studies have assumed that they are phenotypically independent and robust. Although there are sampling biases in the present study, it is noteworthy that the results for all five factors depicted by the NEO-PI-R were comparable to those reported by Western researchers, and the genetic structure of the five-factor model is complex.

Adolescent↗
PubMed2002

[Personality and personality disorders II. The Specificity of the DAPP-model as a diagnostic system for personality disorders].

The 'Dimensional Assessment of Personality Pathology - Basic Questionnaire' (DAPP) measures 18 traits to provide a systematic representation of the overall domain of personality disorders (PD). The present study investigated the relationships between DAPP personality profiles and dimensional assessments of DSM-IV PD in general population subjects (n = 156), and a sample of 220 nonpsychotic psychiatric patients (including n = 67 PD patients). Using nonmetric multidimensional scaling models the similarities between the 18 DAPP-factors and the dimensional scores of the 12 DSM-IV PD (inclusive appendix) were graphically represented in a 2-dimensional similarity-system. Here each DSM-IV PD dimension could be described by a distinct profile of DAPP-factors. Overall results support the assumption that PD can be represented by a dimensional system of personality traits with sufficient sensitivity and specificity.

Humans↗
PubMed2004

Individual growth curve analysis illuminates stability and change in personality disorder features: the longitudinal study of personality disorders.

BACKGROUND: The long-term stability of personality pathology remains an open question. Its resolution will come from prospective, multiwave longitudinal studies using blinded assessments of personality disorders (PD). Informative analysis of multiwave data requires the application of statistical procedures, such as individual growth curve modeling, that can detect and describe individual change appropriately over time. The Longitudinal Study of Personality Disorders, which meets contemporary methodological design criteria, provides the data for this investigation of PD stability and change from an individual growth curve perspective. METHODS: Two hundred fifty subjects were examined for PD features at 3 different time points using the International Personality Disorders Examination during a 4-year study. Stability and change in PD features over time were examined using individual growth modeling. RESULTS: Fitting of unconditional growth models indicated that statistically significant variation in PD features existed across time in the elevation and rate of change of the individual PD growth trajectories. Fitting of additional conditional growth models, in which the individual elevation and rate-of-change growth parameters were predicted by subjects' study group membership (no PD vs possible PD), sex, and age at entry into the study, showed that study group membership predicted the elevation and rate of change of the individual growth curves. Comorbid Axis I psychopathology and treatment during the study period were related to elevations of the individual growth trajectories, but not to rates of change. CONCLUSIONS: From the perspective of individual growth curve analysis, PD features show considerable variability across individuals over time. This fine-grained analysis of individual growth trajectories provides compelling evidence of change in PD features over time and does not support the assumption that PD features are traitlike, enduring, and stable over time.

Adolescent↗
PubMed2002

Assessment is not enough: the SPA should participate in constructing a comprehensive clinical science of personality. Society of Personality Assessment.

Several proposals for a comprehensive clinical science of personality are enumerated in this Klopfer award article, namely (a) the need to integrate the study of personality within a framework of universal principles from which its theories can be derived, its categories organized, its assessment tools constructed, and its therapeutic interventions designed; (b) the wisdom of conceptualizing personality disorders, not as discrete "disease entities" but as psychological prototypes; (c) the shift from the Diagnostic and Statistical Manual of Mental Disorders Axis I to Axis II distinction to a 3-part complexity continuum demarcated by simple reactions, complex syndromes, and personality patterns; (d) the utility of expanding the range and comparability of routinely appraised clinical domains; and (e) the refining and differentiation of personality style and personality pathology subtypes.

Diagnostic and Statistical Manual of Mental Disord↗
PubMed2006

Sadistic personality disorder and comorbid mental illness in adolescent psychiatric inpatients.

Sadistic personality disorder (SPD) is a controversial diagnosis proposed in the DSM-III-R, but not included in the DSM-IV. Few studies have focused on this disorder in adolescents. This article describes the results of a study that sought to determine the presence of sadistic personality characteristics in psychiatrically hospitalized adolescents and of comorbid Axis I or personality disorder patterns in those youth with SPD or SPD traits. Fifty-six adolescents were assessed for sadistic and other personality disorders with the Structured Interview for DSM-III-R Personality Disorders-Revised (SIDP-R). Axis I disorders were assessed using the Diagnostic Interview for Children and Adolescents, Adolescent Version (DICA-R-A) and portions of the Schedule for Affective Disorders and Schizophrenia for School Age Children, Epidemiologic (K-SADS-E). The youth were divided into those with SPD and SPD traits, the Sadistic Group (n = 18), and the Nonsadistic Group (n = 38). A significant proportion of the adolescents in this study met full DSM criteria for SPD (14%). The Sadistic Group (32%) had significantly more Axis I and personality pathology than did the Nonsadistic Group. However, all but one in the Sadistic Group met criteria for other personality disorders, confounding the interpretation of these findings and consistent with adult literature studies. Subjects with sadistic personality characteristics were identified in this adolescent inpatient sample, and they had more extensive Axis I and II psychopathology than the comparison group. The validity of this disorder in younger populations requires further study. Future studies should also explore the impact that the mandatory use of the pleasure/gratification criterion has on the validity of the SPD diagnosis and whether the requisite presence of this criterion decreases the overlap currently noted between SPD and other Axis II diagnoses.

Adolescent↗