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At least 253 records · Page 14Linked to original sources
PubMed1984

A case of strangulation with postmortem amputation of the penis.

A case of homicide with postmortem amputation of the penis was described. The penis found later in a home freezer in the apartment of the culprit showed "zigsaw" fit to the victim. In order to substantiate the morphological findings, phenotypes of three isozymes, phosphoglucomutase1 (PGM1), phosphogluconate dehydrogenase (PGD), and esterase D (EsD) together with ABO blood type were determined in the skin of the penis amputated. All of the four genetic markers determined with the penis were the same as those determined with heart blood of the victim.

ABO Blood-Group System↗
PubMed1984

[A report of self-amputation of the penis with subsequent complication of myiasis].

A 38-year-old male was admitted to our emergency ward on Oct. 27, 1982, because of severe pain at his penoscrotum. Upon physical finding on admission, his penis was found to have been completely amputated 2 cm distally near the root with a razor by himself to commit suicide a few days before admission. On the affected part were much coagulated blood mass and slough and moreover there were 50 maggots about 5 mm long swarming and wrigling, but no bleeding yet and little sign of inflammation. After exclusion of these maggots and cleaning the slashed surface, cutaneous urethrostomy was performed. Postoperative course was favorable but we could not prevent the patient from leaping to his death 45 days after the operation. Self-amputation of the penis with subsequent complication of myiasis is a very rare condition. Since the report of self-amputation of the penis by Matsushita in 1937, this case is the 16 th in Japan. In most cases the patients had mental disorder. In this case the patient was schizoid. On the other hand, 133 cases of myiasis were reported in Japan from 1903 to 1983. In the present case the species that caused myiasis was Lucilia ampullacea. A very rare case of self-amputation of the penis with subsequent complication of myiasis is documented with a review of the literature on this subject.

Adult↗
PubMed1983

RituaL mutilation. Subincision of the penis among Australian Aborigines.

Subincision of the penis is a traditional ritual mutilation unique to the Aborigines, the indigenous people of Australia. The mutilation is a urethrotomy in which the undersurface of the penis is incised and the urethra slit open lengthwise. Subincision is one element in the initiation of Aboriginal youths. In later ceremonies, repeated throughout adult life, the subincised penis is used as a site for ritual bloodletting. There also exists a ritual of penis holding which occurs when a subincised man enters a strange camp. The origin of subincision and the reason for its localization to the Australian continent has not been satisfactorily explained. The mutilation is still performed among tribal Aborigines, and identifies a man as holding a position of status within the tribe.

Australia↗
PubMed1994

Local recurrence of squamous cell carcinoma of the penis.

Given the excellent local control rates achieved with partial penectomy, it is important to consider laser treatment or radiation therapy of squamous cell carcinoma of the penis cautiously. Emotional issues surrounding preservation of a functional penis should not be allowed to compromise adequate therapy. On the other hand, some penile cancers undoubtedly can be managed adequately by techniques other than partial penectomy. The fundamental question is, then, how great a compromise laser treatment or radiation therapy introduces. In patients who present with bulky, long-neglected penile cancers, the point is moot: Partial or even total penectomy is indicated. However, other treatments are feasible in many patients, and an attempt at functional organ preservation should not be restricted simply to the rare small tumor. Lesions up to 2 cm in size can be controlled adequately without amputation. Because tumor grade correlates highly with depth of invasion, the presence of nodal metastasis, and survival, most poorly differentiated squamous cell tumors of the penis probably should be treated by amputation. As mentioned above, it may be several months after laser treatment or radiation therapy before local treatment failure is recognized. Although this is a concern, it probably does not ultimately result in therapeutic compromise in most patients. With most urologic cancers, local recurrence equates with the inability to cure the patient and, ultimately, death. With locally recurrent carcinoma of the penis, however, the situation can be salvaged by converting to partial penectomy. Thus, the patient compromises his chances for cure only if tumor dissemination occurs during the few months between the end of treatment and recognition of failure.

Brachytherapy↗
PubMed1994

Buried penis as a contraindication for circumcision.

Neonatal circumcision is a frequently performed procedure with rare complications. Buried penis is an infrequent congenital penile deformity. If unrecognized, circumcision of these infants may have serious consequences. Buried penis refers to a penile shaft that is buried below the surface of the prepubic skin because of an abnormally prominent suprapubic fat pad and dense fascial bands retracting and tethering the penis. Description of the entity and operative repair are discussed. Avoidance of neonatal circumcision in patients with buried penis is imperative to prevent worsening of the condition.

Circumcision, Male↗
PubMed1993

[The role of magnetic resonance in the evaluation of pathological processes involving the penis].

The above paper was aimed at defining the usefulness of MRI in the study of pathologies involving the penis. Disorders considered include Peyronie's disease, fibrosis of the penis, priapism, trauma, congenital anomalies, and tumors. In Peyronie's disease and in fibrosis of the penis, MRI permits to demonstrate the abnormal thickening of tunica albuginea and erectile tissue; after administration of gadolinium, it becomes possible in some cases to demonstrate plaques of the albuginea that are not palpable. In priapism, MRI is useful both for identifying the cause and for assessing the time elapsed since blood extravasation. In traumatic and congenital pathologies, MRI is essential for the acquisition of all information on anatomy that may be useful for selecting the most suitable surgical therapy. In neoplastic pathology, MRI has proved useful for accurately assessing the extension of lesions involving the basis of the penis.

Diagnosis, Differential↗
PubMed1996

Surgical management of the buried penis.

BACKGROUND: Buried penis is a congenital abnormality in which the phallus is concealed within the surface of prepubic skin. It is probably more common than is generally recognized. The objective was to describe the pathophysiology, and search for the best management of this disease. METHODS: Over a period of 6 years, a total of 31 cases receiving surgery for buried penis at this hospital were analyzed. According to their major pathophysiology, patients were divided into three groups: in the first, the major mechanism was poor skin suspension; in the second, prominent suprapubic fat pad was the major cause. In the third group, the dartos fascia was abnormally thickened and attached to the penile shaft. Different surgical techniques were applied in the different groups. RESULTS: All 15 children in the first group had satisfactory results after penile skin fixation. In the second group, nine children underwent adjunctive lipectomy but only five had satisfactory results. Seven patients in the third group needed degloving of the penis and the three cases who underwent preputial unfurling had severe lymphedema of the inner preputial layer. One of them received revision. The end results were good in the other six patients after long-term follow up. CONCLUSIONS: The buried penis occurs in a spectrum. Although, there are three major pathophysiology mechanisms, most of the patients had a combination. Surgical management should be individualized, and results are usually satisfactory. For the obese patient, weight loss is important. Preputial unfurling and using inner preputial layer to cover the defect should be avoided because of severe postoperative lymphedema.

Child↗
PubMed1996

[Diseases of the penis--the morphological diagnosis of biopsy material].

Diseases of the penis account for a minor part of the general biopsy materials sent for examination, and usually represent varying in nature inflammatory processes and tumors. In the laboratory of andrology and mammary pathology of the department of pathoanatomy and cytopathology with the Alexander Hospital-Sofia, a total of 65 biopsies from the penis are investigated over an eight-year period. The greatest share of the latter is assigned to tumors and tumor-like processes (47.7 per cent), next ranking chronic nonspecific and granulomatous inflammatory processes (29.9 per cent), induratio penis plastica (18.5 per cent) and other diseases. Among the tumors carcinoma of the penis is the commonest (77.4 per cent); in 87.5 per cent it is a matter of flat-cellular, prevailingly highly differentiated neoplasm, and in 12.5 per cent-verrucous, posing considerable difficulties in histological differentiation from papillary benign neoplasms. Diagnosis may be rendered difficult in some of the seldom encountered granulomatous inflammations-sarcoidosis, sclerosing lipogranuloma.

Adolescent↗
PubMed1996

[Unusual cause of acute penile deformity: thrombosis of the superficial dorsal vein of the penis].

OBJECTIVES: To analyze a case of acute shortening and dorsal bending of the penis arising from a thrombosed superficial vein of the penis. METHODS: Patient history, physical examination and duplex US findings are detailed. RESULTS: With a duplex US scan showing no venous flow in the dorsal vein proximal to the root of the penis and after penile fracture, paraphimosis and the presence of foreign bodies had been discarded, the diagnosis was easily made and the lesion completely healed in two weeks. CONCLUSIONS: In evaluating penile deformities, thrombosis of the superficial dorsal vein of the penis must be considered.

Acute Disease↗
PubMed1998

[Incarceration of the penis with a heavy metallic object].

OBJECTIVE: To report an additional case of incarceration of the penis by a heavy metallic object. METHODS/RESULTS: A case of incarceration of the penis by a heavy metallic object (3400 gm) that was resolved by multiple puncture of the glans penis is described. After release, no complications were observed; penile morphology was completely recovered, erectile function was preserved and micturition was normal. CONCLUSION: Multiple puncture of the glans penis was demonstrated to be useful in the management of this case of penile incarceration.

Adult↗
PubMed1983

A, B, O(H) blood group antigen distribution in normal skin and squamous cell carcinoma of the penis.

The distribution of A, B, O(H) blood group antigens was studied in paraffin sections of 4 and 11 specimens, respectively, of normal skin and squamous cell carcinoma of the penis using specific red cell adherence (SRCA) test. In the normal skin of the penis the antigens appeared on the uppermost cornifying layers, while basal and malpighian layers were devoid of antigens. In squamous cell carcinoma of the penis the antigens were either absent or confined only to the epithelial pearl formations. Each of the 4 normal skins and 3 of the 11 carcinomas were antigen positive. As the blood group antigens were frequently absent in patients with carcinoma of the penis regardless of the tumor grade and stage as well as patient's condition, they lack the power to discriminate invasive potential.

ABO Blood-Group System↗
PubMed1991

Metastasis to the penis. Case reports and review of the literature.

Metastasis to the penis is rare, despite rich vascularization and complex circulation. Less than 200 cases have been reported. Three new cases of penis metastasis from primary tumours in the bladder and prostate, respectively, are described. The most common symptoms are penile induration and swelling. Treatments, all of which must be considered merely palliative, consist of local tumour excision, radiation therapy, cytostatic and hormone therapy, possibly with partial or total penis amputation. The prognosis is poor, irrespective of the therapy and site of the primary tumour. More than 80% of the patients die within six months after the occurrence of penis metastasis, as a result of disseminated cancer disease.

Adenocarcinoma↗
PubMed2007

[Urethral duplication in a male child. Accessory urethra with a normotopic opening in a penopubic epispadias with dorsal penis deviation].

Urethral duplication is a rare deformity which can present in various forms, commonly together with other congenital malformations. The embryological genesis is unknown. The isolated deformity is most often found in young males, while for young females it is very rare. We report the case of a 1.5 year old male child having a duplicate urethra with penopubic epispadias and dorsal penis deviation. The child, with known penopubic epispadias grade II and dorsal penis deviation, presented for pediatric urological consultation involving additional diagnostics and therapy. Examination revealed a penopubic epispadias with an external urethral exit at the base of the penis. A preoperative micturating cystogram led to the diagnosis of an accessory central as well as an epispadic urethra. We then carried out urethral reconstruction with the surgical combination of both urethras into a single functioning unit. The penis deviation was corrected after Ransley in the same operation. The postoperative course and aftercare showed normal micturition with a normotopic urethral entry as well as a good urine stream without evidence of a stricture or residual urine. An duplicate urethra is an uncommon malformation which is, however, found more often in male patients. Surgery is based on the individual and must be planned dependent on the morphology present. In all cases, both functional and cosmetic aspects must be taken into account.

Cystoscopy↗
PubMed1992

Metastasis to the penis from malignant melanoma: case report and review of the literature.

A case of metastatic malignant melanoma to the shaft of the penis is described and the literature reviewed to collate the incidence of primary sites which metastasize to the penis. Less than 260 cases of metastasis to the penis have been reported. Of these, 76% are from genitourinary primary sites and 17% are from gastrointestinal primary sites but only one case of metastatic melanoma to the penis has been previously reported. The described case presented with painful priapism while receiving combination chemotherapy for metastatic disease. A CT scan demonstrated a deposit in the left corpora cavernosa and needle aspiration cytology of a plaque attached to the shaft confirmed malignant melanoma cells. Palliation of the painful priapism was achieved by treatment with radiotherapy using large doses per fraction. Retrograde venous or lymphatic spread may have been the cause of a metastasis at this site. Prognosis is very poor.

Adult↗
PubMed2001

Radiation therapy alone or combined surgery and radiation therapy in squamous-cell carcinoma of the penis?

To assess the prognostic factors and the outcome in patients with squamous-cell carcinoma of the penis, a retrospective review of 41 consecutive patients with non-metastatic invasive carcinoma of the penis, treated between 1962 and 1994, was performed. The median age was 59 years (range: 35-76 years). According to the International Union Against Cancer (UICC) 1997 classification, there were 12 (29%) T1, 24 (59%) T2, 4 (10%) T3 and 1 TX (2%) tumours. The N-classification was distributed as follows: 29 (71%) patients with N0, 8 (20%) with N1, 3 (7%) with N2 and 1 (2%) with N3. Forty-four per cent (n=18) of the patients underwent surgery: partial penectomy with (n=4) or without (n=12) lymph node dissection, or total penectomy with (n=1) or without (n=1) lymph node dissection. 23 patients were treated with radiation therapy alone, and all but 4 of the patients who were operated upon received postoperative radiation therapy (n=14). The median follow-up period was 70 months (range 20-331 months). In a median period of 12 months (range 5-139 months), 63% (n=26) of the patients relapsed (local in 18, locoregional in 2, regional in 3 and distant in 3). Local failure (stump in the operated patients, and the tumour bed in those treated with primary radiation therapy) was observed in 4 out of 16 (25%) patients treated with partial penectomy +/-postoperative radiotherapy versus 14 out of 23 (61%) treated with primary radiotherapy (P=0.06). 15 (83%) out of 18 local failures were successfully salvaged with surgery. In all patients, 5- and 10-year survival rates were 57% (95% confidence interval (CI), 41-73%) and 38% (95% CI, 21-55%), respectively. The 5-year local and locoregional rates were 57% (95% CI, 41-73%) and 48% (95% CI, 32-64%), respectively. In patients treated with primary radiotherapy, 5- and 10-year probabilities of surviving with penis preservation were 36% (95% CI, 22-50%) and 18% (95% CI, 2-34%), respectively. In multivariate analyses, survival was significantly influenced by the N-classification, and surgery was the only independent factor predicting the locoregional control. We conclude that, in patients with squamous-cell carcinoma of the penis, local control is better in patients treated with surgery. However, there seems to be no difference in terms of survival between patients treated by surgery and those treated by primary radiotherapy +/-salvage surgery, with 39% having organ preservation.

Adult↗
PubMed2004

Feline penile erection induced by topical glans penis application of combination alprostadil and SEPA (Topiglan).

The objective of this study was to evaluate the efficacy of topically applied prostaglandin E1 (PGE(1))+5% SEPA (soft enhancement of percutaneous absorption) on the glans penis in a feline erection model. Erectile response after glans penis administration of PGE(1)+5% SEPA cream (Topiglan, MacroChem Co., Lexington, MA, USA) was compared to the erectile response after intracavernosal administration of the triple-drug combination (1.65 mg papaverine, 25 microg phentolamine, and 0.5 microg PGE(1)). The placebo cream and increasing concentrations (0.25%, 2.5 mg/ml; 0.5%, 5 mg/ml; and 1%, 10 mg/ml) of PGE(1)+5% SEPA were applied in a total volume of 0.1 ml via a plastic needle-less syringe. The control triple-drug combination was administrated intracavernosally via a 30-gauge needle at the completion of each experiment to serve as a control reference. With each application of placebo, PGE(1)+SEPA, and the triple-drug combination, changes in intracavernosal pressure and systemic blood pressure were continuously monitored. Topical application of PGE(1)+SEPA induced increases in intracavernosal pressure in a dose-dependent manner, with minimal effects on systemic blood pressure. The increases obtained with 1% PGE(1) Topiglan cream were similar to the intracavernosal pressure values elicited by the standard intracavernosal triple-drug combination. These data demonstrate that topical glans penis application of PGE(1)+SEPA can induce an erectile response in cats with minimal systemic adverse effects. Oral pharmacological agents are the first-line treatment for male ED. Studies investigating the effectiveness of noninvasive modalities such as topical therapy should continue, because these agents have the potential to avoid the systemic effects commonly seen with oral therapies. Additionally, topical therapy may also benefit patients who are unresponsive to oral agents or have explicit contraindications. Topical PGE(1) application to the glans penis may become an important treatment option in selected patients suffering from erectile dysfunction.

Adjuvants, Pharmaceutic↗
PubMed2000

Glomus tumor of the penis.

Glomus tumors of the penis are extremely rare. A patient with multiple regional glomus tumors involving the penis is reported. A 16-year-old boy presented with the complaint of painless penile masses and resection of the lesions was performed. The pathologic diagnosis was glomus tumor of the penis. This is the ninth case of glomus tumor of the penis to be reported in the literature.

Adolescent↗
PubMed2000

Epidermoid cyst of the penis: a case report and review of the literature.

Penile cysts are uncommon. A case of a 7-year-old boy with an epidermoid cyst of the penis is reported. He had an asymptomatic, slowly growing soft mass in the frenulum of the penis. Excision of the mass was performed, and the diagnosis was epidermoid cyst of the penis. No recurrence has been noted within the year since excision. To our knowledge, there have been no previous reports of malignancy developing in cystic disease of the penis. In such cases, clinicians should attempt more appropriate management, involving either watchful observation or complete excision of the cyst, by considering the embryogenesis and nature of the disease.

Child↗