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At least 253 records · Page 14Linked to original sources
PubMed1995

Numbing.

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Attitude to Death↗
PubMed2004

A novel case of numb bum.

Cocaine is a drug with a myriad of pharmacological properties enabling it to be used as a therapeutic agent in medicine. The adverse effects of the recreational use of this drug are often observed in patients presenting to the Emergency Department. This paper describes a patient who presented with unusual symptoms after the rectal administration of cocaine, and the proposed explanation for these symptoms.

Administration, Rectal↗
PubMed2004

Comfortably numb?

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Anesthesia, General↗
PubMed2003

Numb rats walk - a behavioural and fMRI comparison of mild and moderate spinal cord injury.

Assessment of sensory function serves as a sensitive measure for predicting the functional outcome following spinal cord injury in patients. However, little is known about loss and recovery of sensory function in rodent spinal cord injury models as most tests of sensory functions rely on behaviour and thus motor function. We used functional magnetic resonance imaging (fMRI) to investigate cortical and thalamic BOLD-signal changes in response to limb stimulation following mild or moderate thoracic spinal cord weight drop injury in Sprague-Dawley rats. While there was recovery of close to normal hindlimb motor function as determined by open field locomotor testing following both degrees of injury, recovery of hindlimb sensory function as determined by fMRI and hot plate testing was only seen following mild injury and not following moderate injury. Thus, moderate injury can lead to near normal hindlimb motor function in animals with major sensory deficits. Recovered fMRI signals following mild injury had a partly altered cortical distribution engaging also ipsilateral somatosensory cortex and the cingulate gyrus. Importantly, thoracic spinal cord injury also affected sensory representation of the upper nonaffected limbs. Thus, cortical and thalamic activation in response to forelimb stimulation was significantly increased 16 weeks after spinal cord injury compared to control animals. We conclude that both forelimb and hindlimb cortical sensory representation is altered following thoracic spinal cord injury. Furthermore tests of sensory function that are independent of motor behaviour are needed in rodent spinal cord injury research.

Animals↗
PubMed1998

Case of the month: April 1998--30 year old male with perineal numbness.

A 30-year-old male presented with a 2 year progressive course of bowel and bladder dysfunction, mild leg weakness and sensory abnormalities in sacral dermatomes. MRI showed an intra-axial conus medullaris lesion which was excised and identified as a ganglioglioma. The case presents the typical clinical course and histopathology of this unusual lesion which carries a favorable prognosis after gross total removal. Preoperative neurological function in such patients is highly predictive of post-operative outcome.

Adult↗
PubMed1982

Beyond psychic numbing: a call to awareness.

The lesson of Hiroshima is reviewed briefly, the illusions that foster our current preparations for nuclear war are considered, and the psychological effects--personal and political--of our stockpiling of nuclear weapons are examined. It is suggested that, although the situation is desperate, hope may be found in the beginnings of a public awareness that is fostering the movement against nuclear armaments.

Adaptation, Psychological↗
PubMed1983

Death by poverty, arms, or moral numbness.

The plight of children in a world in which weapons are given priority is outlined, and the particular effects on children in the United States of the policies of the present government are described. Ways in which mental health workers--acting as professionals and as citizens--can advocate meaningfully on behalf of social programs vital to children are set forth.

Adolescent↗
PubMed2005

Numb together.

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Animals↗