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Event-related potential N270 is elicited by mental conflict processing in human brain.

We recorded event-related potentials (ERPs) in 15 subjects in order to elicit a N270 of arithmetic conflict. Subjects calculated an arithmetic problem and matched their calculation result to an answer digit. They pressed a button when the presented digit is a true answer (condition 1) and pressed another button when the answer is false (condition 2). ERP components of P90, N130, P180, N200 and late positive component (LPC) were recorded in condition 1. In condition 2, N270 was elicited between N200 and LPC and it peaked at approximately 270 ms (268.6 +/- 29.0 ms at Cz). The peak latency of LPC in condition 2 (405.7 +/- 51.3 ms) is significantly delayed than condition 1 (307.5 +/- 22.7 ms). N270 reflects the endogenous conflict processing in human brain.

Adult↗

Do cognitive processes predict mental health in individuals with rheumatoid arthritis?

The purpose of the present study was to assess the hypothesis that intellectual functioning affects the mental health of individuals with rheumatoid arthritis. Structural equation modeling techniques were used to assess the relative contributions of age, education, intellectual functioning, self-efficacy, and pain to mental health. It was hypothesized that individuals with rheumatoid arthritis who had higher intellectual functioning and higher self-efficacy would report better mental health than those with lower intellectual functioning and self-efficacy. One hundred twenty-one adults aged 34 to 84 with rheumatoid arthritis completed a battery of cognitive tasks, and multiple measures of self-efficacy, pain, and mental health, twice in 1 month. The data provided a good fit to the hypothesized model. Intellectual functioning was directly related to mental health and, also, indirectly related to mental health through self-efficacy and pain. Older individuals who performed poorly on cognitive tasks reported less self-efficacy, more pain, and poorer mental health than those individuals who performed well on cognitive tasks.

Adult↗

Psychosomatic medicine--past, present, and future.

"Psychosomatic" is not part of the average person's vocabulary, and most educated laymen know the meaning of "psychophysiological" and "somatopsychic." Without having words for the process, everyone senses that mental processes can influence bodily functioning and, certainly, that the sick body can produce a sick mind. Many explanations have been offered for the mechanisms underlying these processes--theories ranging from the irrational and religious to the philosophical and scientific. Scientific interest in these processes has been a relatively recent development, originating perhaps a few decades ago. It is time to take inventory, to review and consider the scientific history of psychosomatic medicine and the current status of the field. It is also fascinating to speculate on the developments and ramifications of psychosomatic medicine in the future.

Forecasting↗

Intensive studies of patients and the experiences of investigators and clinicians.

Mental processes, normal or abnormal, are complex and multifaceted, needing to be viewed from diverse perspectives. But our field has split increasingly into two discrete groups. One group includes those investigators and clinicians who are often seen as most scientific and have restricted themselves more and more exclusively to directly observable, generally superficial phenomena and patients as classified according to those phenomena. Such variables can be reliably rated, a crucial aspect of any scientific endeavor. But in this group there has been a tendency to be like the person who lost the keys in the middle of the block but looked for them at the corner because "the light is better here." Those of us in this group have tended to act as though, if we can't measure a phenomenon with relative ease, it doesn't exist--potentially the antithesis of an adequate science. Others, and they have become rarer, have focused on understanding the psychological processes of individuals with mental disorder in great depth, while paying less attention to questions of scientific approaches to proof.

Female↗

Some effects of aging on event-related potentials during a linguistic monitoring task.

Two groups of adults, one young and one elderly, were compared on a dichotic task in which continuous speech was monitored for grammatically and semantically anomalous words. Event-related potentials (ERPs) elicited by these anomalies were analyzed in terms of peak amplitude and peak latency of the evoked late-positive component (LPC). Results showed that while LPC peak amplitudes were overall reduced for the group of seniors, LPC peak latencies were similar between both groups of listeners. These findings are consistent with the hypothesis that elderly persons can offset declines in memory, perceptual processes, and speed of mental processing by taking advantage of contextual and prosodic cues in running speech. Additionally, an apparently asymmetric processing negativity was observed in the waveforms of young adults but not seniors. Possible mechanisms include the N400 response to semantic incongruity and a processing negativity component associated with attentional bias toward right hemispace.

Acoustic Stimulation↗

The dynamics of interhemispheric compensatory processes in mental imagery.

The capacity to generate and analyze mental visual images is essential for many cognitive abilities. We combined triple-pulse transcranial magnetic stimulation (tpTMS) and repetitive TMS (rTMS) to determine which distinct aspect of mental imagery is carried out by the left and right parietal lobe and to reveal interhemispheric compensatory interactions. The left parietal lobe was predominant in generating mental images, whereas the right parietal lobe was specialized in the spatial comparison of the imagined content. Furthermore, in case of an rTMS-induced left parietal lesion, the right parietal cortex could immediately compensate such a left parietal disruption by taking over the specific function of the left hemisphere.

Adaptation, Physiological↗

Construct validity of the Kaufman Assessment Battery for Children with mildly mentally retarded students.

The construct validity of the Kaufman Assessment Battery for Children (K-ABC) with mildly mentally retarded children was examined. Subjects were given three intelligence tests: the K-ABC, WISC-R, and Stanford Binet, Form L-M. Analysis of variance procedures revealed differences between the K-ABC Mental Processing Composite and the WISC-R Full Scale IQ, whereas the Stanford-Binet IQ was not reliably different from either. Correlational analysis provided supportive evidence that the K-ABC is measuring general intelligence; however, discrepancy between Sequential/Simultaneous scales and intersubtest correlations may not support distinct processing styles for mildly mentally retarded students, although this sample represents a restricted range.

Achievement↗