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Evaluation of some laboratory procedures in diagnosing infections with Schistosoma mansoni.

THIS PAPER REPORTS ON A COMPARATIVE EVALUATION CARRIED OUT IN PUERTO RICO ON THE FOLLOWING PROCEDURES USED IN DIAGNOSING BILHARZIASIS: recovery of S. mansoni ova from stools; serological tests (complement-fixation tests with adult worm and cercarial antigens, slide flocculation test with cercarial antigens, cercarial agglutination test, and circumoval precipitin test) and intradermal tests with adult worm, cercarial and egg antigens.Stool examinations revealed infections in only 74% of 485 patients hospitalized for bilharziasis, but most of the serological and intradermal tests gave results which, when corrected for false negative reactions, suggested infections in 89%-94% of patients. Cercarial agglutination results were discounted because of weak reactions and low specificity; the intradermal test with egg antigen lacked specificity.From the results of their comparative studies, the authors suggest particular uses for the various serological and stool tests, but consider that the intradermal tests do not appear to have a definable role in the diagnosis or detection of bilharziasis.

Adult↗

PROSTATITIS; AN EVALUATION OF LABORATORY PROCEDURES AND OF THE EFFECTIVENESS OF NITROFURANTOIN.

An estimate of the pus content of prostatic fluid is as good as a count in a counting chamber. There is no correlation between the pus content and the severity of symptoms. Of all of the criteria for making a diagnosis of prostatitis, the pus content of the fluid is the least important. Culture of prostatic fluid is of very little, if any, value for making a diagnosis or guiding treatment. The results of treatment of chronic prostatitis by prostatic massage only, are as good as those obtained by massage plus nitrofurantoin. Acute and subacute prostatitis responded well to nitrofurantoin, and there seemed less likelihood of recurrence when the drug was continued in small doses for four weeks.

Body Fluids↗