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At least 253 records · Page 14Linked to original sources
PubMed2001

The effect of the skull on event-related P300.

OBJECTIVES: Event-related potentials (EP) indicate neuronal processes with a high temporal resolution, while functional magnetic resonance imaging (fMRI) has a high spatial distribution. Information from both techniques may complement each other. However, this combination is fraught with difficulty because of a possible interference of the skull or the scalp with scalp-recorded EP. The aim of the present study was to investigate this influence of skull and scalp thicknesses on event-related P300 potentials. METHODS: Thirty healthy controls were examined using an auditory evoked P300 elicited by a standard oddball paradigm. Skull and scalp thicknesses were determined using coronal T2-weighted magnetic resonance imaging (MRI). RESULTS: P3b-amplitudes were significantly correlated with temporo-parietal skull thickness (r=-0.42; P=0.021; regression slope of -1.14 microV/mm skull thickness), whereas scalp had no influence on P300. The amplitude of the more frontal subcomponent P3a was not related to frontal skull thickness. CONCLUSIONS: Therefore, the utility of P300 as a research tool can be enhanced when adjustment for skull thickness is made.

Adult↗
PubMed2006

[Pneumonia awareness year, 2004: scientific impact through publications in Archivos de Bronconeumología].

Pneumonia is a common and potentially serious infectious disease. Morbidity and mortality rates continue to be high in spite of major advances and steady progress in diagnosis and treatment. The economic impact of the disease is also great. It is therefore necessary to enlist the public, primary care and emergency physicians, and public policy administrators to join forces to treat and prevent pneumonia for the common good. The annual incidence of pneumonia in the population over the age of 14 years is 1.6 to 2.6 episodes/1000 inhabitants. The mortality rate is 14.1 per 100,000 inhabitants, and the associated costs are 115 million euros annually. The RESPIRA Foundation and the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) declared 2004 to be pneumonia awareness year with the aim of coordinating efforts to raise awareness, distribute information, and foster debate.

Bibliometrics↗
PubMed1993

Perspectives on health technology assessment in Latin America. The case of perinatal care in the literature.

The possibility of referring to the medical literature to support technology assessments in perinatal care was studied by examining more than 40,000 references contained in the Index Medicus of Latin America for the period 1984-88. A total of 1,074 references addressed perinatal technologies, but with irregular distribution. Information on effectiveness, safety, costs, and social impact of perinatal technologies was extremely limited. These results led to the conclusion that immediate action needs to be taken to create the necessary conditions for health technology assessment in Latin America.

Developing Countries↗
PubMed1991

Later rather than sooner: extralinguistic categories in the acquisition of Thai classifiers.

An experimental elicitation task with children between the ages of 1;8 and 11;3 shows that children learning Thai numerical classifiers begin with purely distributional information: specifically, (1) that classifiers must appear in the post-numeral position, and (2) that classifiers comprise a conventional, closed set of words. Semantic organizing features, such as salient features of the head noun's referent, appear later than these syntagmatic organizing features. Use of such semantic information is not an immature 'first guess' at grammatical categories, but rather, a necessary component of adult linguistic competence, because the categories are productive both for older children and for adults.

Child↗
PubMed2001

The role of animacy in children's understanding of 'move'.

Animals are distinctive in that they are the causal agents of their own actions (e.g. a dog moves itself), whereas artifacts generally are not (e.g. a marble doesn't move itself). We examined whether children make use of this conceptual link between animacy and agency when interpreting the verb 'move' in English. Specifically, we hypothesized that the semantic interpretation of 'move' would differ, depending on whether the subject noun refers to an animal or to an inanimate object. We hypothesized that, for in animates, children would allow 'move' to have a patient subject (e.g. 'the marble moved' could mean 'the marble was moved by someone else') but not so for animates (e.g. 'the dog moved' could not mean 'the dog was moved by someone else'). In two studies, 65 three-year-olds, 57 five-year-olds, and 74 adults viewed video clips of animals or inanimate objects being transported by a person. For each clip, the child was asked whether the animal or object was moving. A 'yes' response would indicate acceptance of a patient subject (e.g. 'the dog/marble moved' means 'the dog/marble was moved by someone else'). Both five-year-old children and adults more often reported that the toys were moving, than that the animals were moving. However, three-year-olds showed no animacy effects. Thus, between the ages of three and five, children begin to link animacy and agency in language. These findings suggest that children's language use is guided by similar conceptual constraints as those of adults, and/or that children are sensitive to distributional information linking form and meaning in the input language.

Adult↗
PubMed2005

Effects of site occupancy, cation relocation, and pore geometry on adsorption kinetics in ETS-4.

Strontium-exchanged titanium silicate, Sr-ETS-4, is a new molecular sieve with promises for exciting applications in gas separation. The literature mentions poor thermal stability and low adsorption capacity as the drawbacks of the as-synthesized Na-ETS-4 and therefore the need for cation exchange. Upon ion exchange, Sr-ETS-4 shows appreciable kinetic selectivity between methane and nitrogen, which can be improved further by controlled dehydration. In this study, we trace the changes at the molecular level behind this improvement. By combining distributed information in the literature, it is shown that the governing factors are changes in pore geometry with progressive dehydration, changes in ion occupancy, and relocation of cations due to Sr exchange.

Journal Article↗
PubMed2006

[Successful strategies and methods of nursing standards implementation].

UNLABELLED: Standards and guidelines are useful elements in quality development and helpful to influence practice of health professionals. However, there are some unanswered questions regarding the circumstances and preconditions of effective change in practice. In German research there is a lack of ambitious evaluation studies concerning implementing standards. Getting evidence about supporting and restricting factors of implementing guidelines into nursing practice is the aim of this article. METHOD: With the help of a search of relevant literature in appropriate data bases the research findings are systematically analysed. FINDINGS: Effective implementation and distribution strategies are programs that realise an active involvement of practitioners and that are practically orientated. Passive attempts to distribute information and specification reveal only little success. A multiple intervention program addressing the introduction process and organisational conditions promise the very best influence on the practice of care.

Evaluation Studies as Topic↗
PubMed1989

Reading long words embedded in sentences: informativeness of word halves affects eye movements.

The possibility was explored that the informativeness of a specific region within a word can influence eye movements during reading. In Experiment 1, words containing identifying information either toward the beginning or toward the end were displayed asymmetrically around the point of fixation so that the reader was initially presented with either the informative or noninformative zone. Words were read with shorter summed initial fixation time when the reading was started from the informative zone. In Experiments 2 and 3, the target words were presented in sentences that were to be comprehended. More attention was given to the informative endings of words than to redundant endings. The latter were also skipped more often. The duration of the first fixation was not affected by information distribution within the word, whereas the second fixation duration was. The results of these experiments lend good support to the hypothesis of immediate lexical control over fixation behavior and to the notion of a convenient viewing position.

Adult↗
PubMed1991

Domain structure and sequence distribution in dentin phosphophoryn.

Phosphophoryn (PP) is a protein unique to the mineralized matrix of dentin. It also has a unique composition, with aspartic acid and phosphoserine comprising greater than 85% of all amino acid residues. Because of this unique composition and high content of phosphoserine, it has been difficult to apply direct peptide sequencing procedures effectively. However, to understand its function, and to prepare suitable probes for screening cDNA libraries, some sequence distribution information is required. To this end, using bovine (b) and rat incisor (ri) PPs, partial mild acid hydrolysis has been used to cleave at the aspartic acid residues and generate free amino acids and small peptides. The nature of the released amino acids and peptides has been determined. Peptides have also been generated by limited digestion with trypsin. Some of the peptides have been purified by h.p.l.c. techniques and sequenced. About 90% of the bPP and riPP were resistant to trypsin, and the large resistant fragment was sharply depleted of the non-aspartic acid and non-phosphoserine [(P)Ser] residues. All peptides isolated were acidic, but the remaining residues (other than aspartic acid and serine) appeared to be collected in regions flanking the trypsin-resistant core. These data show directly the presence of regions [Asp]n, [(P)Ser]m and [Asp-(P)Ser-Asp]k as prominent sequence features. A domain structure model is proposed.

Acetates↗
PubMed2001

Signalling from the cell surface to the nucleus.

Transcriptional initiation is regulated by altering the properties of promoter-specific DNA-binding proteins, such that these proteins either show altered interaction with the basal transcriptional machinery, or show changes in their cytoplasmic/nuclear distribution. Information is passed from the receptor to the transcription factor by a process of post-translational modifications of pathway components. Post-translational modifications can include phosphorylations or dephosphorylations, which are reversible, and proteolysis, which is irreversible. Specificity within a linear signal transduction pathway is preserved by the existence of scaffold proteins, which serve to co-localize many of the factors from a given linear pathway.

Animals↗
PubMed2003

Seeking the attitudes and perceptions of the Greek primary-care professionals on voluntary work in caring for people with HIV/AIDS.

BACKGROUND: During the last two decades Greece has moved towards a national health system. However, in a country with limited economic resources the necessity for reducing the increasing costs of the health care services by an effective use of available human resources, such as community volunteers, becomes inevitable. This paper reports the findings of a pilot study on attitudes and perceptions of primary-care staff towards voluntary work for human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients. METHODS: Of the 300 primary-care professionals who are serving the health centres of the largest area of Athens, a sample of 153 was selected. The population surveyed was predominately female (n = 104, 69.3%) and most of them (n = 77, 50.7%) were between 31 and 40 years of age. A 28-item questionnaire was used, especially designed to investigate attitudes and perceptions of primary health care (PHC) professionals regarding the contribution of volunteers to HIV/AIDS-related programmes. RESULTS: Most of the respondents (n = 131, 85.6%) reported little or no experience of caring for HIV/AIDS patients and only 14 (9%) reported participation in any voluntary programmes. Eighty-eight per cent of patients (n = 135) consider the participation of volunteers in AIDS programmes as very useful and the vast majority of the participants pointed out the usefulness of the participation of health professionals and other influencing persons in voluntary programmes. Participants also suggested that sharing time with HIV patients and families, offering emotional support and practical help and distributing information leaflets for the general population should be the volunteers' contribution in AIDS-related programmes. The PHC professionals' role in voluntary programmes is considered by the 91 respondents (59.5%) as 'planning and organizing', for 66 (43.1%), 'coordinating' and for 37 (24.2%), 'supporting'. Although the majority of the participants (n = 90, 58.8%) said they would participate as a volunteer in an AIDS-related programme, only one-third of the total sample (n = 48, 31.4%) agree with the statement that they have a professional duty to support such a type of programme. CONCLUSIONS: Primary-care workers present little experience in caring for HIV/AIDS patients or participating in volunteer programmes and mainly positive attitudes and perceptions to voluntary work. Continuing educational programmes together with awareness activities may increase the involvement of primary-care professionals in the effective management of AIDS in Greece.

Adult↗
PubMed1994

[Communication and integration of medical documents for the teleconference use. An outcome of the BERMED project].

The collaboration between physicians is supported in the BERMED project by implementing the remote access to distributed patient data and the realisation of computer-based medical conferencing. This requires the integration of the multimedia data in form of a meta-patient record for our medical application systems. These applications are supported by a distributed information management promoting access to different information systems, imaging modalities and digital archival storage systems. The features of image processing are concerned with quantification, segmentation and 3-D-visualisation to obtain additional information. This paper gives an overview of the actual state of the teleconferencing system in radiology.

Computer Communication Networks↗
PubMed2004

Delay accuracy in bat sonar is related to the reciprocal of normalized echo bandwidth, or Q.

Big brown bats (Eptesicus fuscus) emit wideband, frequency-modulated biosonar sounds and perceive the distance to objects from the delay of echoes. Bats remember delays and patterns of delay from one broadcast to the next, and they may rely on delays to perceive target scenes. While emitting a series of broadcasts, they can detect very small changes in delay based on their estimates of delay for successive echoes, which are derived from an auditory time/frequency representation of frequency-modulated sounds. To understand how bats perceive objects, we need to know how information distributed across the time/frequency surface is brought together to estimate delay. To assess this transformation, we measured how alteration of the frequency content of echoes affects the sharpness of the bat's delay estimates from the distribution of errors in a psychophysical task for detecting changes in delay. For unrestricted echo frequency content and high echo signal-to-noise ratio, bats can detect extremely small changes in delay of about 10 ns. When echo bandwidth is restricted by filtering out low or high frequencies, the bat's delay acuity declines in relation to the reciprocal of relative echo bandwidth, expressed as Q, which also is the relative width of the target impulse response in cycles rather than time. This normalized-time dimension may be efficient for target classification if it leads to target shape being displayed independent of size. This relation may originate from cochlear transduction by parallel frequency channels with active amplification, which creates the auditory time/frequency representation itself.

Animals↗
PubMed2002

Impaired retention of spatial memory after transection of longitudinally oriented axons of hippocampal CA3 pyramidal cells.

Longitudinally oriented axon collaterals of CA3 pyramidal cells may be critical for integrating distributed information in the hippocampus. To investigate the possible role of this pathway in the retention of spatial memory, we made a single transversely oriented cut through the dorsal CA3 region of each hippocampus. Although the lesion involved <3% of the hippocampal volume, it nonetheless disrupted memory retention in a water maze in preoperatively trained rats. New learning in a different water maze was attenuated. No significant impairment occurred in rats with longitudinally oriented cuts, or in animals with ibotenic acid-induced lesions of similar magnitude. To characterize the effect of a focal lesion on the integrity of longitudinally projecting axons, we stained degenerating cells and fibers in rats with unilateral CA3 transections by using FluoroJade-B. Degenerating terminals were seen across a wide region posterior to the cut, and were present in the strata of areas CA3 and CA1 that are innervated by CA3 pyramidal cells. These results suggest that the integrity of longitudinally oriented, translamellar axons of CA3 pyramidal cells may be necessary for efficient acquisition and retention of spatial memory.

Animals↗
PubMed2003

Description of the soybean pod gall midge, Asphondylia yushimai sp. n. (Diptera: Cecidomyiidae), a major pest of soybean and findings of host alternation.

The soybean pod gall midge is an important pest of soybean in Japan and is known to occur also in Indonesia and China. This gall midge is described from Japan as Asphondylia yushimai sp. n. and is clearly distinguished from its congeners by the arrangement of the lower frontal horns of the pupa and the sequence of the mtDNA COI region. It is concluded that Prunus zippeliana Miquel is a winter host of the soybean pod gall midge since haplotypes of the soybean pod gall midge coincide with those of the Prunus fruit gall midge that produces fruit galls on P. zippeliana. In addition, phenological and distributional information on the two gall midges and on their host plants supports the identification of the winter host. In Japan, the soybean pod gall midge overwinters as a first instar in the fruit galls on P. zippeliana and emerges as an adult from the galls in May. In summer and autumn, the soybean pod gall midge has two or more generations in the pods of soybean, Glycine max (L.) Merrill or wild fabaceous and caesalpiniaceous plants. Thus host alternation by A. yushimai is confirmed. This is the second finding of host alternation by a species of Asphondylia, the first instance being that of Asphondylia gennadii (Marchal) in Cyprus.

Animals↗
PubMedDate not supplied

Delivery outcome among physiotherapists in Sweden: is non-ionizing radiation a fetal hazard?

A cohort study was made on 2,043 infants born to 2,018 females registered as physiotherapists at the time of pregnancy during 1973 to 1978. The incidence of perinatal death, serious malformation, short gestational duration, and low birth weight was slightly below the expected with consideration given to maternal age and parity distribution. Information on occupational exposure (use of shortwave, microwave, and ultrasonic equipment, X-ray exposure, use of electrostimulator or hexachlorophene-containing soaps) was obtained in a case-control study within the cohort from mail questionnaires with a 93% response rate. The only positive finding was a higher incidence of shortwave equipment use among the females with a dead or malformed infant than among controls. Various explanations for this finding are discussed.

Abnormalities, Radiation-Induced↗
PubMed2006

Design of a sampling plan to detect ochratoxin A in green coffee.

The establishment of maximum limits for ochratoxin A (OTA) in coffee by importing countries requires that coffee-producing countries develop scientifically based sampling plans to assess OTA contents in lots of green coffee before coffee enters the market thus reducing consumer exposure to OTA, minimizing the number of lots rejected, and reducing financial loss for producing countries. A study was carried out to design an official sampling plan to determine OTA in green coffee produced in Brazil. Twenty-five lots of green coffee (type 7 - approximately 160 defects) were sampled according to an experimental protocol where 16 test samples were taken from each lot (total of 16 kg) resulting in a total of 800 OTA analyses. The total, sampling, sample preparation, and analytical variances were 10.75 (CV = 65.6%), 7.80 (CV = 55.8%), 2.84 (CV = 33.7%), and 0.11 (CV = 6.6%), respectively, assuming a regulatory limit of 5 microg kg(-1) OTA and using a 1 kg sample, Romer RAS mill, 25 g sub-samples, and high performance liquid chromatography. The observed OTA distribution among the 16 OTA sample results was compared to several theoretical distributions. The 2 parameter-log normal distribution was selected to model OTA test results for green coffee as it gave the best fit across all 25 lot distributions. Specific computer software was developed using the variance and distribution information to predict the probability of accepting or rejecting coffee lots at specific OTA concentrations. The acceptation probability was used to compute an operating characteristic (OC) curve specific to a sampling plan design. The OC curve was used to predict the rejection of good lots (sellers' or exporters' risk) and the acceptance of bad lots (buyers' or importers' risk).

Coffee↗
PubMed2000

Access to employment for people with disabilities: findings of a consumer-led project.

PURPOSE: A consumer led initiative which aimed to gather information from local employers and disabled people which might inform future action to improve work opportunities for disabled people. METHOD: (1) A survey of 500 companies with more than 20 employees randomly sampled from 4 locations across Suffolk was undertaken. The survey generated both numerical and verbal data. Response rate was low (25%) but achieved a reasonable spread of organizations in terms of size, type of industry and geographical location. (2) Semi-structured interviews were carried out with nine disabled people. Open-ended questions were used to elicit information about the nature of their disability, experiences of education and experiences of seeking and/or maintaining work. RESULTS: 43% of respondents had one or more disabled employees. Evidence of obstacles to employment included a lack of understanding about the capability of disabled people, lack of knowledge about financial and technical assistance and undifferentiated approaches to access and accommodation. Interview data supported the importance of paid employment to self esteem and quality of life and showed high levels of frustration in their search for work. CONCLUSIONS: This study demonstrates the need for better interagency communication and a more effective information distribution strategy for employers, particularly in relation to the availability of systems of support and the capability of disabled employees.

Attitude to Health↗