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PubMed1984

[Predisposing and triggering factors in erysipelas].

The authors studied 29 patients with erysipela and considered the immunologic deficit and the filariasis as the principal predisponents factors while local traumatisms and regional superficial mycosis were considered as the most frequent unleashing agents. After treatment of these factors the authors did a follow-up by 1 1/2 year and only 2 patients presented recurrence of the disease in coincidence with recurrence of their feet mycosis.

Adult↗
PubMed1984

[Protective medium for the lyophilization of a live vaccine against swine erysipelas--VR2].

Hydrolysate was obtained through enzyme hydrolysis from waste residual fibrin in the production of hyperimmune swine blood. Fibrin hydrolysate and gelatose in 2.5 : 1.5 ratio were tested as protective medium for the freeze-drying of VR2 vaccine against swine erysipelas. It was found that the freeze-drying of the vaccine with the addition of the hydrolysate-gelatose medium at the rate of 4-5 per cent of the vaccine volume met the requirements of the standard for sterility, innocuity, vaccinal titer, and residual moisture.

Animals↗
PubMed1983

Erysipelas.

Erysipelas is a superficial cellulitis that affects the skin and subcutaneous tissues. There is also prominent lymphatic involvement. Group A streptococci are the usual cause of this painful infection, but the responsible organisms cannot always be cultured from the fiery red, edematous, sometimes vesicular rash. A fulminating case developed in the left leg of a man whose veins had been harvested four months earlier for coronary artery bypass surgery.

Erysipelas↗
PubMedDate not supplied

[Immunopathologic aspects of chronic erysipelas polyarthritis in swine].

Chronic erysipelas polyarthritis in pigs is considered to be an animal model closely resembling human rheumatoid arthritis. In an experimental study using SPF pigs infected with Erysipelothrix rhusiopathiae several immunopathological aspects were studied for up to 14 months after infection. After an initial febrile phase a progressive polyarthritis and discospondylitis developed at 2 weeks after infection. Quantitative determination of IgG and IgM revealed a significant increase in these immunoglobulins both in the serum and the synovia from arthritic joints. Arthritic joints containing viable Erysipelothrix bacteria at termination of the experiment have a higher content of IgG and IgM than bacteriologically negative joints. During the entire experiment the rheumatoid factor titer, determined by the Waaler Rose test, remained relatively low with increases and decreases. The Erysipelothrix antibody titers are highly significant. The total complement activity in the serum increases discontinuously and shows fluctuations similar to those of the rheumatoid factor titer. The highest enzyme activities of acid phosphatase and lactate dehydrogenase are demonstrable in the synovial fluid of arthritic joints with positive bacteriological or immunohistological findings. These joints also have the greatest numbers of IgG-producing plasma cells. By means of immunohistological methods Erysipelothrix antigen can be demonstrated in macrophages of the proliferating synovial membrane. Finally, there is a discussion of the pathogenic significance for the perpetuation of chronic polyarthritis of Erysipelothrix persisting in arthritic joints in spite of focal immune reactions.

Acid Phosphatase↗
PubMed1981

[Fasciitis necroticans -- erysipelas grangrenosum: two different clinical entities? (author's transl)].

Among the bacterial infections of the skin the so called fasciitis necroticans has until now received little attention in dermatological literature. The clinical picture shows great similarity to erysipelas grangrenosum. Considering the fact, that the primary infection involves the subcutaneous fatty tissue and especially in light of the different bacterial etiology with the resulting differences in therapy, it seems justified to classify fasciitis necroticans as a separate entity.

Adult↗
PubMedDate not supplied

Erysipelas in domestic white Pekin ducks.

Two epornitics of erysipelas were diagnosed in domestic White Pekin ducks. The first was in 2,000 18-day-old ducklings with a 30% mortality. The other was in 2,400 breeder hens with losses of four or five birds a day. Gross pathologic lesions in birds necropsied from both instances were enlarged swollen livers with occasional subcapsular hemorrhages. Pure isolates of Erysipelothrix insidiosa only were cultured from the livers. Histologic examination revealed congestion and multifocal necrosis in the liver and spleen with associated reticuloendothelial cell proliferation. Special stains demonstrated numerous organisms within the reticuloendothelial cells.

Animals↗
PubMed1978

[Immune reactivity of piglets vaccinated at an early age with a live vaccine against erysipelas].

Studies were carried out on the immune response in pigs that had been treated at various intervals following birth with a live vaccine against erysipelothrix rhusiopathiae. The pigs originated from sows that had been vaccinated against the disease on the 80th day of pregnancy. Both biologic and morphologic investigation were performed. It was found that passive immunity protected the small pigs against an experimental infection up to the age of 45 days, inhibiting during this period being the action of the vaccine applied. The young pigs built up an active immunity against swine erysipelas after their vaccination at the age of 2 months, which protected them against control challenging, while the nonvaccinated animals reacted with a rise in temperature and reddening at the site of scarification. The morphologic studies confirmed the results of the biologic experiments.

Age Factors↗
PubMedDate not supplied

Erysipelas in quail and suspected erysipeloid in processing plant employees.

Erysipelas was diagnosed in two commercial breeder flocks of Coturnix quail and was characterized clinically by sudden mortality. At necropsy, lesions comprised generalized congestion, hemorrhages in the thigh and breast muscles, swelling of liver, spleen, and kidney, and dark red edematous lungs. Erysipelothrix rhusiopathiae was cultured from visceral organs of affected birds. Medication with penicillin in the drinking water controlled the mortality. A possible source of infection was fish raised on the premises. Seven people at the quail processing plant developed localized inflammation of the fingers, which responded when antibiotic therapy for erysipeloid was initiated.

Animals↗
PubMed1995

[Erysipelas and elephantiasis of the scrotum. Surgical and drug therapy].

Elephantiasis is the outcome of persistent lymphedema. It is refractory to different therapy modalities. The social approachability of patients with this disease is impaired by severe functional and cosmetic disturbances. The causal relationship between etiology and recurrent disease is demonstrated by two cases. Treatment options are discussed. Radical surgery is decisive for primary success since chronic inflammation and chronic edema support each other. Metabolic equilibrium, disinfecting skin areas and antibiotic prophylaxis are urgent steps in the successful treatment of Erysipelas disease.

Adult↗
PubMedDate not supplied

[The development of a technology for the production of live dried vaccines against avian pasteurellosis and swine erysipelas].

The technology of the production of dried live vaccine against Pasteurella infection of fowl from Pasteur's 2nd avirulent strain, strains AB and K, has been developed. This technology includes the process of batch cultivation of Pasteurella cells, controlled in such parameters as eH, pO2 and glucose concentration, in fermenters in optimized culture medium, based on Hottinger hydrolysate and fermentative casein-yeast hydrolysate, and preservation in improved saccharose-gelatin medium prepared in potassium sulfate buffer solution. The new technology makes it possible to increase the yield of preparations with stable biological activity 5- to 13-fold in comparison with the traditional technology. Furthermore, the technology of the production of live dried vaccine against swine erysipelas from Erysipelothrix insidiosa strain BP-2 has been developed. This technology is based on maintaining the optimum conditions of the batch cultivation of E. insidiosa in meat medium based on Hottinger hydrolysate and media obtained from hydrolysate of pancreatic fermentation products of microbial biomass; the preparation thus obtained is stabilized in peptone-saccharose-gelatin medium prepared in potassium phosphate buffer solution. This increases the yield of the vaccine 8-fold in comparison with the traditional technology, while ensuring the stability of bacteria after drying and during prolonged storage.

Animals↗
PubMed1976

[Therapy and prophylaxis of recurrent erysipelas (author's transl)].

17 patients suffering from chronically recurrent erysipelas were treated through 10 days - every day - with 10 mega Na-penicillin G intravenously, before noon, and with 1.2 mega (900000 units clemizole penicillin G plus 300000 units Na-penicillin G) intramuscularly or 1 to 2 mega penicillin V acid orally, in the afternoon. Thereafter, these patients were to be injected through six months, in two week intervals, a repository penicillin (600000 units benzathine penicillin G, 300000 unmand in a divers manner. During the observation period from 1 7/12 to 2 8/12 years, 11 out of 17 patients remained without relapse. Frequency of recidivation significantly decreased in 3 patients; no improvement was achieved in the three last patients.

Administration, Oral↗
PubMed1993

Prophylactic application of Propionibacterium avidum KP-40 in swine with acute experimental infections. II. Bacterial infections: pleuropneumonia and swine erysipelas.

The potent immunomodifier Propionibacterium avidum KP-40 (PA) demonstrated prophylactic potency in swine infected experimentally with Haemophilus (Actinobacillus) pleuropneumoniae or Erysipelothrix rhusiopathiae. Animals received PA either together with the respective vaccine or PA only; 3 resp. 4 weeks later all animals were inoculated with virulent pathogens. Eight of 10 swine immunized with inactivated pleuropneumonia vaccine developed mild-moderate forms of infection with temporary stagnation of body weight; application of the vaccine together with PA lowered the morbidity rate to 1 of 10 (p < 0.05). Also in non-vaccinated swine infected with pleuropneumonia or erysipelas PA application resulted in milder clinical symptoms, faster recovery and a larger gain of body weight.

Actinobacillus Infections↗
PubMed1993

[Spontaneous splenic rupture associated with facial erysipelas].

Spontaneous rupture of the spleen is rare Although over 100 cases have been reported, only a few were of true spontaneous rupture. Most cases were associated with diseases which directly involved the spleen. We report a 53-year-old woman with facial erysipelas and true spontaneous rupture of the spleen.

Erysipelas↗
PubMed1993

[Facial erysipelas].

Facial erysipelas is quite uncommon today in Denmark. However, as the disease may be fatal without the proper treatment, the necessity for definite diagnosis is stressed on the basis of a case.

Diagnosis, Differential↗
PubMed1997

[Efficacy of pefloxacin in the treatment of complicated relapsing erysipelas].

The effect of antimicrobial agents on the clinical and immunological indices was comparatively studied in 30 patients with relapsing erysipelas complicated by pyoderma. The patients were treated with pefloxacin in a daily dose of 800 mg for 7-10 days (15 patients) and with the routine antibiotics such as benzylpenicillin, ampicillin and erythromycin (15 patients). The efficacy of the treatment was defined by disappearance of the clinical signs and normalization of the functional immunity status. The pefloxacin effect was evident at early stages of the treatment and observed at least for 3 months after the patient discharge from the hospital. Gradual elimination of the secondary immune deficiency in the convalescents due to sanitation of the infection chronic foci was recorded.

Aged↗
PubMed1998

Acute nonfatal erysipelas in sows in a commercial farrow-to-finish operation.

Acute nonfatal erysipelas was diagnosed in 4 sows in a 1,000-sow commercial farrow-to-finish operation in Indiana. Sows were pyrexic, lethargic, lame, and had multiple, 1.3- to 7.6-cm, erythematous rhomboid skin lesions. Outbreak was attributed to failure to properly vaccinate pigs. Further morbidity and mortality were prevented by treatment of clinically affected sows and all pigs in close proximity with procaine penicillin G daily for 3 consecutive days and vaccination of all pigs with questionable vaccination status, using bacterin of killed Erysipelothrix rhusiopathiae. Periodic review of herd management protocols is important to ensure that recommended vaccination schedules are being followed and animals are receiving quality vaccinations. Human error can contribute to many production problems and should be included on the differential diagnoses list.

Animals↗