Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “DRESSINGS”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 253 records · Page 14Linked to original sources
PubMed2004

Influence of dressing changes on wound temperature.

OBJECTIVE: When wound-tissue temperature falls below 33 degrees C neutrophil, fibroblast and epithelial cell activity decreases. This study examined the influence of dressing changes on wound temperature. METHOD: The wound-bed temperatures of patients with a wound resulting from trauma or surgical debridement were measured immediately before and after dressing changes using a DermaTemp infrared body surface scanning device. The temperature on the surface of the dressing product was measured immediately before the dressing change and then every five minutes it until the pre-procedural temperature was reached. RESULTS: A total of 133 dressing episodes were measured, yielding 266 wound-bed temperature measurements and 619 external dressing temperature measurements. Pre-procedural temperatures showed that the wound beds were on average marginally below the 33 degrees C threshold immediately after dressing takedown (mean: 32.7 degrees C). This figure dropped two degrees on average as a result of the dressing-change procedure (mean: 29.9 degrees C). Reapplied wound-dressing products return to the pre-procedural temperature within 30 minutes (mean: 23 minutes). CONCLUSION: This study provides baseline data for future research aimed at promoting maintenance of a normothermic wound bed. DECLARATION OF INTEREST: None.

Adult↗
PubMed2001

A randomized trial comparing povidone-iodine to a chlorhexidine gluconate-impregnated dressing for prevention of central venous catheter infections in neonates.

UNLABELLED: Neonates who require a central venous catheter (CVC) for prolonged vascular access experience high rates of catheter-related bloodstream infection (CRBSI). PURPOSE: A multicenter randomized clinical trial was undertaken to ascertain the efficacy of a novel chlorhexidine-impregnated dressing (Biopatch Antimicrobial Dressing) on the CVC sites of neonates for the prevention of catheter tip colonization, CRBSI, and bloodstream infection (BSI) without a source. Setting. Six level III neonatal intensive care units. Patients Studied. Neonates admitted to study units who would require a CVC for at least 48 hours. METHODS: Eligible infants were randomized before catheter placement to 1 of the 2 catheter site antisepsis regimens: 1) 10% povidone-iodine (PI) skin scrub, or 2) a 70% alcohol scrub followed by placement of a chlorhexidine-impregnated disk over the catheter insertion site. A transparent polyurethane dressing (Bioclusive Transparent Dressing) was used to cover the insertion site in both study groups. Primary study outcomes evaluated were catheter tip colonization, CRBSI, and BSI without an identified source. RESULTS: Seven hundred five neonates were enrolled in the trial, 335 randomized to receive the chlorhexidine dressing and 370 to skin disinfection with PI (controls). Neonates randomized to the antimicrobial dressing group were less likely to have colonized CVC tips than control neonates (15.0% vs 24.0%, relative risk [RR]: 0.6 95% confidence interval [CI]: 0.5-0.9). Rates of CRBSI (3.8% vs 3.2%, RR: 1.2, CI: 0.5-2.7) and BSI without a source (15.2% vs 14.3%, RR: 1.1, CI: 0.8-1.5) did not differ between the 2 groups. Localized contact dermatitis from the antimicrobial dressing, requiring crossover into the PI treatment group, occurred in 15 (15.3%) of 98 exposed neonates weighing </=1000 g. No neonates in the PI group developed contact dermatitis. CONCLUSION: The novel chlorhexidine-impregnated dressing, replaced weekly, was as effective as cutaneous disinfection with 10% PI and redressing the site every 3 to 7 days for preventing CRBSI and BSI without a source in critically ill neonates requiring prolonged central venous access. The risk of local contact dermatitis under the chlorhexidine dressing limits its use in low birth weight infants who require prolonged central access during the first 2 weeks of life.

Administration, Cutaneous↗
PubMed2005

Effect of a silicone-containing dressing on exuberant granulation tissue formation and wound repair in horses.

OBJECTIVE: To determine the effect of a silicone dressing on the rate and quality of repair of limb wounds and compare microvascular occlusion and apoptosis in wounds treated with the silicone dressing and those treated with a conventional dressing in horses. ANIMALS: 5 horses. PROCEDURE: Horses received two 6.25-cm2 wounds on each metacarpus. Ten wounds were treated with a silicone dressing; the other 10 were treated with a control dressing. Quality of repair and wound size were evaluated at each bandage change. Time to healing and the number of excisions of exuberant granulation tissue were recorded. Biopsy specimens taken from healed wounds were evaluated semiquantitatively via histologic examination, p53 immunohistochemical analysis, terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL) to quantify apoptosis, and electron microscopic examination to measure microvessel luminal diameters. RESULTS: The silicone dressing surpassed the conventional dressing in preventing formation of exuberant granulation tissue and improving tissue quality. Microvessels were occluded significantly more often in wounds dressed with the silicone gel, which also diminished the expression of mutant p53, an indirect inhibitor of apoptosis, although greater apoptosis was not confirmed quantitatively by use of TUNEL. CONCLUSIONS AND CLINICAL RELEVANCE: Because the silicone dressing inhibited the formation of exuberant granulation tissue, it may be integrated in a management strategy designed to improve the repair of limb wounds in horses.

Animals↗
PubMedDate not supplied

Enhanced wound contraction in fresh wounds dressed with honey in Wistar rats (Rattus Novergicus).

BACKGROUND: Due to reports that honey accelerates wound healing, an investigation on its role in wound contraction in fresh wounds inflicted on wistar rats was carried out. METHOD: Twenty adult male wistar rats had 2cm by 2cm square wound inflicted on their right dorsolateral trunk. They were divided into two groups. The experimental group had their wounds dressed with honey while the control group had normal saline dressing. Wound dressing was done every five days and measurements taken at each dressing. Wound morphology was also assessed. RESULTS: Dressing with honey significantly enhanced percentage wound contraction on day 10 with value of 79.20+/-2.94 compared to control value of 53.50+/-4.32. p=0.0. The mean wound measurement on day 10 reduced significantly in honey group, 1.15+/-0.18 compared to control group 2.38+/-0.28. p=0.002. However, there was no significant difference in fibroblast count per high power field in honey group 68.0+/-2.59 compared to control 90.2+/-17.40, p=0.242. Honey dressing increased mean blood vessel count per high power field, 18.8+/-3.77 albeit non significantly when compared to control value of 13.4+/-2.44, p=0.264. Also honey dressing caused increased granulation tissue formation in wounds dressed with honey compared to control group. CONCLUSION: Our study suggests that honey dressing enhances wound contraction in fresh wounds which is one of the key features of wound healing.

Administration, Cutaneous↗
PubMed2000

Microbiological conditions of sheep carcasses from conventional or inverted dressing processes.

At a small abattoir, 25 sheep carcasses were dressed conventionally, with the carcass suspended by the rear legs, and 25 carcasses were dressed while inverted, with the carcasses suspended by the forelegs. Two swab samples were obtained from randomly selected sites on each carcass, and total aerobic, coliform, and Escherichia coli counts were enumerated for each sample. Each type of count was arranged in two sets of 25 counts for each type of dressing process, and a log mean number and/or log total number recovered was calculated for each set of counts. The log mean number of total aerobic counts for one set of counts from carcasses dressed while inverted was less than the corresponding log mean numbers for both sets from the conventionally dressed carcasses and the other set from the carcasses dressed while inverted, and differed from them by about 0.7 log units. The coliforms recovered from carcasses were largely E. coli. The log total numbers of coliform or E. coli counts recovered from carcasses dressed while inverted were about 1.5 log units less than the corresponding log total numbers recovered from conventionally dressed carcasses. Those data indicate that the substitution of inverted for conventional dressing might serve to reduce the numbers of E. coli on sheep carcasses by reducing the microbiological contamination of the hindquarters but that the general microbiological condition of the carcasses would be little improved unless some means of preventing or removing contamination of the forequarters was also used.

Abattoirs↗
PubMed1999

Clinical efficacy and cost-effectiveness of a new synthetic polymer sheet wound dressing.

Stage II and III pressure ulcers present product development and product choice challenges to manufacturers and professional wound care clinicians respectively. We evaluated the clinical performance and cost of use associated with a new synthetic polymer dressing for the management of these wounds. A total of 10 home healthcare patients, each with a Stage II or III pressure ulcer, were enrolled and randomized for wound treatment using either the new polymer hydrogel wound dressing or the leading market hydrocolloid dressing. Dressings were changed on an as needed basis only. The wounds were assessed weekly and parameters recorded using the Bates-Jensen Pressure Sore Status Tool. In addition, the clinical performance of the dressing and treatment costs were evaluated. The overall healing rate for the two groups was similar. However the new polymer hydrogel dressing was found to have a more favorable overall clinical performance evaluation based largely on its more favorable support of autolytic debridement. The new polymeric dressing also had a more favorable cost of use based on the evaluation. We conclude that the new polymer dressing may be a favorable alternative to the leading market hydrocolloid dressing for the treatment of Stage II and III pressure ulcers due to a better clinical performance and the substantially lower treatment costs associated with its use.

Adult↗
PubMed2003

Evaluation of two calcium alginate dressings in the management of venous ulcers.

Calcium alginate dressings facilitate the management of highly exudating wounds such as venous ulcers. To evaluate and compare the performance of two calcium alginate dressings in the management of venous ulcers, a prospective, randomized, controlled clinical study was conducted among 19 outpatients at two wound clinics in California. Ten patients (53%) were treated with Alginate A and nine patients (47%) with Alginate B. Dressings were changed weekly and patients were followed for a maximum of 6 weeks or until the venous ulcer no longer required the use of an alginate dressing. At each dressing change, the wound was assessed and dressing performance evaluated. Absorbency of exudate, patient comfort during wear, ease of removal, adherence to wound bed, dressing residue following initial irrigation, patient comfort during removal, ease of application, and conformability were assessed. Patients using Alginate A experienced significantly less foul odor (P = 0.02) and less denuded skin (P = 0.04) than Alginate B at follow-up wound assessments. With the exception of conformability, Alginate A was rated significantly better than Alginate B (P less than or equal to 0.05) in all dressing performance assessments. No significant healing differences were observed. As the different performance characteristics of various calcium alginate dressings become more obvious in clinical practice, further study is warranted to determine their optimal effectiveness.

Aged↗
PubMedDate not supplied

Postoperative dressing and management strategies for transtibial amputations: a critical review.

Postamputation management is an important determinant of recovery from amputation. However, consensus on the most effective postoperative management strategies for individuals undergoing transtibial amputation (TTA) is lacking. Dressings can include simple soft gauze dressings, thigh-high rigid cast dressings, shorter removable rigid dressings, and prefabricated pneumatic dressings. Postoperative prosthetic attachments can be added to all but simple soft dressings. These dressings address the need to cleanly cover a fresh surgical wound, but not all postoperative dressings are designed to facilitate the strategic goals of preventing knee contractures, reducing edema, protecting from external trauma, or facilitating early weight bearing. The type of dressing and management strategy often overlap and are certainly interrelated. Current protocols and decisions are based on local practice, skill, and intuition. The current available literature is challenging, and difficulties include variations in healing potential, in comorbidity, in surgical-level selection, in techniques and skill, in experience with postoperative strategies, and with poorly defined outcome criteria. This paper reviews the published literature and compares measures of safety, efficacy, and clinical outcomes of the various techniques. Analysis of 10 controlled studies supported only 4 of the 14 claims cited in uncontrolled, descriptive studies.

Amputation, Surgical↗
PubMed2006

[Preventing nosocomial infections. Dressings soaked in polyhexamethylene biguanide (PHMB)].

Polyhexamethlene biguanide (PHMB) is an antibacterial agent included in the chlorhexidine group which is active against a wide number of microorganisms including Staphylococcus Aureus Methycilin Resistant (MRSA), Vancomycin Resistant Enterococcus Faecalis (VRE) and Acinetobacter baumannii which all cause antibiotic-resistant infections. Traditionally gauze dressings have been used to cover and protect wounds although their porous structure does not constitute an efficient barrier against bacterial penetration, especially when a dressing becomes wet due to the effects of a wound oozing and draining. Recently the use of a dressing soaked in a 0.2% PHMB solution which works as a biological barrier against pathogenic agents has been introduced in clinical practice. On the one hand, this PHMB soaked dressing inhibits bacterial growth in the areas where it is applied and, on the other hand, it prevents the penetration of microorganisms through the dressing itself. Simultaneously while a PHMB soaked dressing carries out these actions, it creates an environment favorable to the proliferation of the normal flora found in the epidermis. As opposed to porous gauze dressings, a PHMB dressing remains active during 72 hours even in wet environs. Its wide anti-micro-bacterial range prevents infections in surgical, acute or chronic wounds and in any type of intra-corporal access susceptible to infection, such as by means of intravascular catheters, tracheotomies, or thoracic tubes. A PHMB dressing can also be used as a primary covering to treat a chronic wound since it does not interfere in the process of tissue reepithelization.

Anti-Bacterial Agents↗
PubMed1990

Semipermeable dressing and transepidermal water loss in premature infants.

Within the first days of life, 10 infants, of 32 weeks' gestational age or less, began 2 weeks of treatment with a semipermeable wound dressing over a small area of skin. The effects of the dressing on transepidermal water loss and cutaneous microflora were evaluated. Transepidermal water loss from the semipermeable dressing-treated skin was significantly less than that from the untreated skin immediately after placement of the dressing (8.1 +/- 1.8 g/m2.h-1 vs 17.7 +/- 3.5 g/m2.h-1, P less than .0001). The normal accelerated skin maturation process that occurs in these infants continued beneath the semipermeable dressing. The number of gram-negative bacilli or other bacteria did not increase beneath the semipermeable dressing beyond that seen on the untreated site. Malassezia furfur was found only on the control site, never beneath the semipermeable dressing. According to results of this preliminary study, a semipermeable dressing can be safely used in premature infants and the use of a semipermeable dressing may decrease the excessive transepidermal water loss associated with prematurity.

Bacteria↗
PubMed1988

[Experimental testing of the hydrogel dressing Geliperm].

The dressing materials used in the local treatment for dressing large defects of skin, subcutaneous and muscular tissues do not have the optimum protective and therapeutic properties. We carry out experiments tending to achieve new kinds of dressing impermeable for microorganisms, free from toxic, allergic, action and acridity and not evoking pathological tissue reaction in a long-lasting contact with the wound. What is more, the new dressing should hasten the cicatrization process of a wound and enable its control as well as soothe the pain if it is possible. Some of these properties were achieved by the usage of cross-linked hydrophilic polymers with high ability of water absorption, creating elastic gels in its presence. The dressing of this type called Geliperm was produced by Geistlich Sons Ltd. and BYK Goldbin-Konstanz firms. The methods of evaluation of hydrogel dressing materials comprising a preliminary, standard and qualifying evaluation were worked out in the Department of Experimental Surgery and Biomaterials Research Medical Academy of Wrocław. According to the worked out scheme of experiments the Geliperm dressing was evaluated. We have discovered on the basis of the carried out experiments that the new generation of gel dressing has, to a large extent, the properties of the so called "ideal dressing".

Animals↗
PubMed1981

Effect of laminar air flow and clean-room dress on contamination rates of intravenous admixtures.

The effect of laminar air flow conditions and clean-room dress on the microbial contamination rates of intravenous admixtures was investigated. Intravenous admixtures were prepared by one investigator using aseptic technique under four environmental conditions: laminar air flow conditions with clean-room dress; laminar air flow without clean-room dress; clean table top with clean-room dress; and clean table top without clean-room dress. In each environmental condition, 350 admixtures were compounded. Negative-control samples (n = 150) were also tested, as were 10 positive-control samples. Samples were tested in each of two growth media and incubated at 35 degrees C for 14 days or until growth occurred. The incidence of contamination of admixtures compounded in laminar air flow conditions was significantly less than the contamination of those compounded on a clean table top (p less than 0.05) regardless of the operator's dress. The incidence of contamination of admixtures compounded while wearing clean-room dress was not significantly different from those prepared while not wearing clean-room dress regardless of the environment in which the admixture was prepared. The overall low level of contamination [0.79% (11/1400)] was inconclusive regarding the effect of dress on the incidence of contamination when admixtures were prepared under LAF conditions. It is concluded that, when one adheres to aseptic technique, the environment in which admixtures are compounded is the most important variable affecting the microbial contamination rate.

Drug Compounding↗
PubMed2003

Central venous catheter dressings: a systematic review.

BACKGROUND: Gauze and tape or transparent polyurethane film dressings such as Tegaderm, Opsite or Opsite IV3000 are the most common types of dressing used to secure central venous catheters (CVCs). Currently, there are no clear guidelines as to which type of dressing is the most appropriate. AIMS: To identify whether there are any differences between gauze and tape and/or transparent polyurethane film dressings in the incidence of CVC-related infection, catheter-related sepsis, catheter security, tolerance to dressing material, dressing condition and ease of application in hospitalized patients. METHODS: The Cochrane Controlled Trials Register and Medline, Embase and CancerLit databases were searched to identify any controlled trials comparing the effects of gauze and tape and/or transparent polyurethane dressings on CVCs. Additional references were sought from published and non-published literature. Twenty-three studies were reviewed. Data were extracted independently from each paper by two members of the review team and results compared. Differences were resolved either by consensus or referral to a third person. Authors were contacted for missing information. RESULTS: Of the 23 studies reviewed, 15 were excluded. Of the remaining eight, data were available for meta-analysis from six studies. Of the six included studies, two compared gauze and tape with Opsite IV3000, two compared Opsite with Opsite IV3000, one compared Tegaderm with Opsite IV3000, and one compared Tegaderm with Opsite. CONCLUSIONS: There was no evidence of any difference in the incidence of infectious complications between any of the dressing types compared in this review. Each of these comparisons was based on no more than two studies and all of these studies reported data from a small patient sample. Therefore it is unlikely that any of these comparisons would have had sufficient power to detect any differences between groups.

Bandages↗
PubMedDate not supplied

Use of a cell-based interactive wound dressing to enhance healing of excisional wounds in nude mice.

The need to have viable, metabolically active cells to heal wounds is well recognized, because there is clear evidence that cellular dysfunction delays healing. This suggests that addition of metabolically active cells to a delayed healing tissue could enhance the healing of the tissue. Therefore, we examined the ability of an interactive wound dressing composed of human keratinocytes or fibroblasts grown on microporous bio-reactor beads and placed into a polyethylene bag to facilitate the delayed healing of wounds in nude mice. A 1 x 1 cm wound was made on the backs of nude mice, and the dressing with or without viable cells was placed on the wound for 8 to 24 days, with dressing changes every other day. Wound area and time to heal measurements were compared after various interventions including freeze-thawing. The data shows that the interactive wound dressing was more effective than the control dressings (p<0.05) and that keratinocytes were more effective than fibroblasts in wound healing (p<0.05). Freezing-thawing of the interactive wound dressings destroyed the activity of the dressing. Studies examining cells using a live/dead viability assay showed that both keratinocytes and fibroblasts were alive after 2 days on the mice. Surprisingly, human fibroblasts appeared to exhibit bridging behavior that is indicative of fibroblast proliferation. We conclude that a simple interactive wound dressing using either keratinocytes or fibroblasts can enhance the healing of wounds in nude mice.

Animals↗
PubMed1999

The role of Mepitel silicone net dressings in the management of fingertip injuries in children.

Forty-five children with isolated fingertip injuries were randomized for treatment with either Mepitel silicone net dressings or paraffin gauze dressings. Over a 4 week period, the objective adherence of the dressing, and the perceived level of stress caused to the child by the dressing change were scored by linear analogue scales. The wounds were also assessed for the progress of healing and presence of infection. Twenty children received Mepitel dressings and 25 had paraffin gauze dressings. There was no difference in duration of healing or complication rates between the two groups. Statistically lower scores were seen for the Mepitel group for the first 3 weeks in both adherence and stress scores. These results suggest that silicone net dressings may be a less adherent and less painful method of dressing fingertip injuries in children.

Bandages↗
PubMed2000

Low-level laser therapy for wound healing: feasibility of wound dressing transillumination.

OBJECTIVE: The purpose of this study was to assess the feasibility of exposing wounds during low-level laser therapy (LLLT) by transillumination of the wound dressings. BACKGROUND DATA: LLLT has been associated with accelerated wound healing in chronic ulcers. The usual approach is to remove wound dressings prior to exposure and to treat three to five times weekly. Frequent change of wound dressings is time consuming and costly; it disrupts the healing process, increases the risk of wound infection, and may be traumatic for the patient. METHODS: A double integrating sphere setup was employed to quantify the diffuse transmittance and reflectance of various wound dressings. Differences in transmittance for large area sources and point sources were demonstrated through the use of a diode laser and an incoherent light source. RESULTS: There were a number of gels and membrane style wound dressings with diffuse transmittance of more than 50%. Hence, for these dressings the prescribed radiant exposure to the wound surface could be achieved by increasing the exposure duration, while maintaining reasonable overall treatment times. CONCLUSIONS: Although LLLT by transillumination of wound dressings is feasible for a variety of wound dressings without significant commitments in additional treatment time, the specific transmission of products not included in this study needs to be determined at the intended treatment wavelength. A transillumination approach may facilitate a faster rate of wound healing than LLLT applied to exposed wounds by reducing trauma and the risk of infection.

Absorption↗
PubMed1982

Amniotic membranes as dressings following facial dermabrasion.

Facial dermabrasion produces a raw, painful, partial-thickness wound, quite similar to a split-thickness skin graft donor site. The various methods of dressing such wounds employing ointments, impregnated gauze, bulky absorptive dressings, xenografts, or allografts are time consuming, uncomfortable for the patient, and not infrequently characterized by localized purulence and delayed healing. Experience with amniotic membranes as biologic dressings, both experimental and clinical, prompted a trial of these membranes as a dressing following facial dermabrasion. Thirty-three patients undergoing facial dermabrasion were dressed with amniotic membranes following the procedures. The results following this dressing method were excellent. The biologic basis and the techniques of preparing and applying amniotic membranes as dressings following facial dermabrasion are presented. The advantages of amniotic membranes over the other presently employed dressing techniques following facial dermabrasion are discussed.

Amnion↗
PubMed1993

Occlusive dressings.

BACKGROUND: Although occlusive dressings speed epithelialization, reduce inflammation and tenderness, reduce the chance of infection, stimulate healing of chronic wounds, and produce less scarring, they are still underutilized by physicians and nurses. The principal reasons for their underutilization are fear of infection, the time needed for instructing patients in their use, a lack of knowledge about occlusive dressings, and the general unavailability and high cost of the dressings. METHODS: This chapter describes the principles which help in selection of the proper dressing, discusses the mechanisms of action of occlusive dressings, lists some novel new occlusive dressings, and emphasizes some of the drawbacks of occlusive dressings for chronic wounds. CONCLUSION: While occlusive dressings have become an important treatment protocol, their role in opening the minds of clinicians to the possibility of controlling the repair process may be their greatest contribution to medical science.

Humans↗