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PubMed1975

[Determination of immunoglobulins in acute and chronic coronary disease].

51 patients with chronic ischaemic heart disease showed on the average increases of IgA and IgG, but a significance concerning a control group could not be calculated. Compared with the normal group 41 patients with acute myocardial infarction did not reveal a significant increase of all three immunoglobulins. The observations of the course after myocardial infarction had the following result: During the first five days IgG in the majority decreased to 90% of the initial value and in the second to third week it increased to a maximum of on the average 150% of the initial value. 8 patients did not show a change of the IgG-level after infarction, in 4 patients the IgG-level still continuously decreased also in the second week. In 23 patients IgA increased to the double in the second and third week, in 18 patients it remained uninfluenced. The increase of IgM was to be established in 15 patients in whom at the same time in increase of IgA appeared. A relation between the values of IgG and the clinical parameters of the myocardial infarction could not be proved.

Acute Disease↗