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Multiple sites of impingement of a tracheal tube as it is advanced over a fibreoptic bronchoscope or tracheal tube introducer in anaesthetized, paralysed patients.

Impingement of the tracheal tube on upper airway structures occurs commonly during advancement over a fibreoptic bronchoscope or introducer. In this descriptive study a fibrescope was used to assess the site and mechanism of tracheal tube impingement during advancement over a variety of fibreoptic bronchoscopes and introducers during orotracheal intubation in anaesthetized adults. The effect of the 90 degree counterclockwise rotation manoeuvre in overcoming impingement was also assessed. We recorded impingement at the right arytenoid, left arytenoid, epiglottis, interarytenoid tissue and the left pyriform fossa. Our study found a wider range of sites at which impingement may occur than in previous studies. We also found that when 90 degree counterclockwise rotation of the tip of the tracheal tube was achieved, the impingement was reliably overcome.

Adolescent↗

Bronchoscopic insufflation of room air for the treatment of lobar atelectasis in mechanically ventilated patients.

Segmental and lobar pulmonary atelectasis is a common occurrence in mechanically ventilated patients. Standard therapy for atelectasis relies on positive pressure ventilation, positive and expiratory pressure (PEEP), tracheobronchial toilet and regular chest physiotherapy. Various adjuncts to physiotherapy such as bronchoscopic clearance of secretions have not proved to be of additional benefit. Bronchoscopic clearance of secretions followed by insufflation of room air at 30 cm H2O into the atelectatic segment was employed on ten occasions in mechanically ventilated patients. Rapid re-expansion of the collapsed segment or lobe occurred in seven out of the ten treatments.

APACHE↗

Quantitative bronchoscopic assessment of airway collapsibility in newborn lamb tracheae.

To date, quantitative studies of the inherent characteristics of the developing airway wall have required excision of an airway segment or surgical creation of an isolated segment. We hypothesized that airway wall characteristics, at various collapsing pressures, and attendant changes in stiffness after smooth muscle stimulation could be quantitated bronchoscopically from airway pressure-area relationships. Neonatal lamb tracheal segments (n = 12) were suspended over hollow mounts, in a buffer-filled chamber, and subjected to a range (0 to -4.0 kPa) of pressures to determine wall stiffness under collapsing forces before and after stimulation of the trachealis with methacholine. Luminal images were recorded through a 3.6-mm flexible bronchoscope under the same conditions, subsequently corrected for distortion, and a cross-sectional area was quantitated. Both pressure-volume and pressure-area relationships detected significant changes in airway wall stiffness after methacholine administration (p < 0.002), and the magnitude of change was similar between methods. These data suggest that quantitative flexible bronchoscopy can be used clinically in the intact airway to assess wall stiffness.

Animals↗

Comparative studies using a rigid thoracoscope and fiberoptic bronchoscope to treat spontaneous pneumothorax.

Prior to 1978, the conventional treatment of pneumothorax generally consisted of conservative therapies such as rest, needle puncture, or thoracic cavity drainage; however, when conservative therapies were ineffective or relapse occurred therapeutic approach, 34 percent (11/32) of our patients required a thoracotomy. Consequently, in 1981, we began to use alternative therapies to reduce the need for thoracotomy. In this report, we describe the results of using a rigid thoracoscope and fiberoptic bronchoscope for the treatment of spontaneous pneumothorax. Initially, we treated 31 of 79 patients with a rigid thoracoscope and electrocoagulation therapy. Therapy was effective in 17 (55 percent) of the patients. Only 13 (16 percent) of the 79 patients required a thoracotomy, which represents a 50 percent reduction in incidence. Of the 14 cases in which therapy was ineffective, the major cause of failure was our inability to view a broad thoracic area and treat all blebs with a rigid thoracoscope. Subsequently, we developed a method using a fiberoptic bronchoscope (FB), which allows an unrestricted view of the thoracic area, in combination with electrocoagulation and fibrinogen or thrombin solution (or both) for the treatment of spontaneous pneumothorax. We treated 19 of 39 patients with the FB method. Treatment was effective in 15 (80 percent) of the patients. Only 4 (10 percent) of the 39 patients required a thoracotomy, which is a reduction of over 60 percent in our original incidence.

Adult↗

Protected specimen brush in the assessment of ventilator-associated pneumonia. Selection of a certain lung segment for bronchoscopic sampling is unnecessary.

The protected specimen brush (PSB) with quantitative cultures is one of the most reliable techniques for assessing pneumonia in mechanically ventilated (MV) patients. The need to select a certain lung segment for bronchoscopic sampling is still debated. We investigated whether the results of PSB specimens collected within an area radiographically involved with pneumonia (inv-PSB) differed from the results of PSB specimens collected within a lung area without radiographic abnormalities (non-inv-PSB) in 39 MV patients with suspected pneumonia. The comparison of bacterial titers of inv-PSB and non-inv-PSB cultures did not disclose significant differences. Agreement regarding the diagnosis of pneumonia according to recommended diagnostic threshold was observed in 34 of 39 patients (87.1 percent). These results which are in accordance with the pathophysiology of ventilator-associated pneumonia and histologic studies do not support the need to select a certain lung segment for bronchoscopic sampling in most MV patients with suspected pneumonia.

Acinetobacter Infections↗

Use of an ultrathin bronchoscope in the assessment of central airway obstruction.

STUDY OBJECTIVE: To assess the utility of an ultrathin bronchoscope (UB) in the assessment of central airway obstruction (CAO). DESIGN: Prospective evaluation SETTING: Tygerberg Hospital, a tertiary teaching hospital. PATIENTS: Consecutive patients referred to the Lung Unit with CAO. INTERVENTIONS: Fiberoptic bronchoscopy (FOB) was performed with a prototype UB (Olympus BF XP40; Olympus Europe; Hamburg, Germany; outer diameter, 2.8 mm; working channel, 1.2 mm). The UB was used whenever a standard bronchoscope (SB) could not pass the obstruction or could not be tolerated by the patient. MEASUREMENTS AND RESULTS: Data relating to indication and performance of FOB, patient demographics, utility in establishing a diagnosis, and planning definitive management were documented. Twenty-four patients (17 men; mean age, 46 years) were studied. Twelve patients (50%) had malignant CAO, 8 patients (33%) had benign tracheal stenosis, 3 patients (12.5%) had stent occlusion, and 1 patient (4%) had bilateral vocal cord paralysis. In 42% of patients, an initial attempt at passing the obstruction with an SB had failed. Vocal cords or trachea were involved in 62% of patients. The mean luminal occlusion was 84% of the total airway lumen (range, 50 to 100%). One complication (desaturation) led to early termination of FOB. In all but three patients with complete obstruction, the UB was able to pass the CAO and allowed assessment of the obstruction and the distal airways (87%). CONCLUSION: UB-FOB was useful and safe in the assessment of patients with CAO from both benign and malignant disease. It aided in establishing a diagnosis and/or planning of definitive management in all patients examined.

Adult↗

Pleuroscopy and cautery control of intrathoracic hemorrhage with a flexible fiberoptic bronchoscope.

Intrathoracic hemorrhage from adhesions torn by a spontaneous pneumothorax is relatively uncommon. Continued hemorrhage from such adhesions after the evacuation of 1,500 ml of blood would usually require thoracotomy for control. Through a flexible fiberoptic bronchoscope, we confirmed the source of hemorrhage and cauterized the bleeding point. This case illustrates another application for pleuroscopic examination, further broadening the use of the flexible fiberoptic bronchoscope.

Adult↗

Control of high density bacterial contamination of the fiberoptic bronchoscope.

In a double-blind study the fiberoptic bronchoscope was contaminated with five pathogenic organisms, each at a concentration of 10(9) organisms per milliliter. The shaft and inner channel of the bronchoscope were cleansed with five antiseptic regimens. Each regimen included equal 120-ml aliquots of one, two, or three solutions, respectively. The five different regimens were as follows: (1) physiologic saline solution; (2) 70 percent solution of isopropyl alcohol, followed by physiologic saline solution; (3) alkaline glutaraldehyde, followed by 70 percent solution of isoproply alcohol, followed by physiologic saline solution; (4) benzalkonium chloride, followed by 70 percent isopropyl alcohol, followed by physiologic saline solution; and (5) povidone-iodine solution, followed by 70 percent solution of isopropyl alcohol, followed by physiologic saline solution. The four regimens involving solutions other than saline solution alone were effective in reducing the count of residual bacterial colonies to 10(4) colonies per milliliter or less.

Alcohols↗

The use of a new ultra-thin fiberoptic bronchoscope to determine endotracheal tube position in the sick newborn infant.

The various techniques available for determining endotracheal tube position after intubation of a newborn are auscultation of the chest, observation of distance rings on the endotracheal tube, and chest radiology. Radiology is considered to be the most reliable method. We evaluated the use of a new ultra-thin fiberoptic bronchoscope on 20 recently intubated newborn infants to determine the position of the endotracheal tube and compared the technique with radiology. The accuracy of the two methods was comparable (correlation 0.91, P less than 0.001). Adverse changes in transcutaneous PO2 were observed during both procedures but were more marked during radiology than bronchoscopy. We conclude that the bronchoscopic technique of determining endotracheal tube position is both as safe and as accurate as radiologic technique.

Airway Resistance↗

Reliability of the bronchoscopic protected catheter brush in intubated and ventilated patients.

The reliability of a bronchoscopic protected catheter brush (BPCB) in the diagnosis of lower respiratory tract infection was studied in 17 intubated and ventilated patients, including seven patients free from such infection (group 1) and ten patients with suspected infection (group 2). A first sample was obtained in the lower trachea by aspiration through the fiberoptic bronchoscope and a second in a distal bronchus by the BPCB procedure. In group 1, all BPCB cultures were sterile, although lower tracheal cultures yielded two or more bacterial species, showing that uncontaminated specimens can be obtained by the BPCB procedure. In three patients of group 2, BPCB cultures remained sterile as a nonbacterial pulmonary disease was certified by open lung biopsy. In seven patients from group 2, BPCB cultures yielded all of the organisms isolated simultaneously by reference methods (ie, cultures of blood or pleural fluid, serologic tests, and open lung biopsy). In two of these patients, contamination of the BPCB specimens was ascertained by the reference method bacterial results. In this study the BPCB procedure was able to obtain uncontaminated specimens in intubated and ventilated patients and was mainly accurate in identifying the bacterial etiologic agents of lower respiratory tract infections.

Adult↗

The flexible bronchoscopic approach to lung volume reduction.

Surgical lung volume reduction is effective in patients with chronic obstructive pulmonary disease (COPD) because it improves the ratio between residual lung volume and total lung volume. The same effect may be achieved by inducing an iatrogenic atelectasis in one or more lung lobes using a flexible bronchoscopic approach. This article discusses the origin and the progress, up to date, of this new minimally invasive flexible bronchoscopic approach.

Bronchoscopes↗

Percutaneous tracheostomy by guidewire dilating forceps technique: is bronchoscopic guidance mandatory?

BACKGROUND AND OBJECTIVE: Percutaneous tracheostomy is a blind technique where-in bronchoscopy is advocated but is rarely practiced. Our study is aimed at evaluating the potential safety of this procedure when performed without bronchoscopic guidance. METHODS: This is a retrospective analysis of seventy-eight patients who underwent percutaneous tracheostomy using the Guide Wire Dilating Forceps method for prolonged periods of ventilation and/or for bronchial toileting for various underlying diseases. The procedure time and various complications were noted and compared with the historical controls from the literature. RESULTS: The mean duration of the procedure was 3.09 +/- 0.49 minutes with a range of 1.5 to 14 minutes in comparison to 8.9 minutes with a range of 2 to 33 minutes as in literature where-in bronchoscopy was used. No major perioperative complications were encountered. Two patients (2.6%) had persistent peristomal oozing as an early complication when compared to that in the literature (12.5%) (p < 0.05). Twenty-seven patients were decannulated, with good tissue approximation (mean: 3.51 days). CONCLUSIONS: In the absence of bronchoscopic guidance, percutaneous tracheostomy can be performed safely and speedily if simple precautions like ensuring free aspiration of air on needle insertion into trachea, bubbling of fluid placed over the hub of the cannula during ventilation and free mobility of guide wire at each step of the procedure were observed to secure the right positioning of the tracheostomy tube.

Adolescent↗

Bronchoscopic laser photodestruction of benign tumours in the trachea and large bronchi.

Potentialities and results of laser bronchoscopic surgery of exophytic benign tumours of the trachea and bronchi are described. The material includes 37 patients (33 men and 4 women) aged 28-69 (mean age 51 years). Tumours were removed by the Nd-YAG laser. In six patients laser photodestruction was combined with electrosurgery. In 31 patients manipulations were done via bronchofiberscope under local anaesthesia and in six patients via a rigid bronchoscope under general anaesthesia. Complete removal of pathologic tissues was achieved in all patients. During 1-5 years of follow-up none of the patients developed recurrent tumours.

Adult↗

[Thoracoscopy with two bronchoscopes in 50 patients with pleural effusion of unknown origin].

When performing thoracoscopy in patients with pleural effusion of unknown origin, we used two bronchoscopes simultaneously, one for observation and one for biopsy. A total of 50 patients with pleural effusion of unknown origin were studied. In all of those studies, pleural effusion was exudative, lymphocyte-dominant, had a low level of adenosine deaminase, no malignant cells, and no tuberculosis or other bacteria in pleural effusion smears. Fourteen were out-patients. A catheter was inserted into the pleural space under local anesthesia, and 300 ml to 500 ml of pure oxygen was injected to create a pneumothorax. Two flexible fiberoptic bronchoscopes were used simultaneously, one for observation and one for biopsy. Approximately 1 hour after the examination, the out patients were able to return home. Lesions in the pleural cavity were found in 42 of these 50 patients, and histological diagnosis was possible in 46. This is a simple procedure with no major side effects. The equipment required is familiar to pulmonary physicians, and the diagnostic yield is high.

Adult↗

Bronchoscopically administered recombinant human DNase for lobar atelectasis in cystic fibrosis.

Lobar atelectasis is a common complication of cystic fibrosis. The majority of cases respond to intravenous antibiotics and chest physiotherapy. In a subgroup of patients, atelectasis is resistant to medical therapy, and its persistence in the pediatric population is associated with a poor prognosis. Bronchoscopic instillation of human recombinant DNase expanded atelectatic lobes in three children resistant to at least 2 weeks of medical therapy. This method of administration of DNase has been successful in resistant cases of lobar atelectasis in patients with chronic obstructive pulmonary disease, quadriplegia, and status asthmaticus. Purulent cystic fibrosis sputum has a very high DNA content, and DNA has been shown to become more pourable in vitro when treated with rhDNase. Bronchoscopic instillation of rhDNase should be considered in cases of persistent lobar atelectasis unresponsive to medical therapy.

Bronchoscopy↗

Predictive camera tracking for bronchoscope simulation with CONDensation.

This paper exploits the use of temporal information to minimize the ambiguity of camera motion tracking in bronchoscope simulation. The condensation algorithm (Sequential Monte Carlo) has been used to propagate the probability distribution of the state space. For motion prediction, a second-order auto-regressive model has been used to characterize camera motion in a bounded lumen as encountered in bronchoscope examination. The method caters for multimodal probability distributions, and experimental results from both phantom and patient data demonstrate a significant improvement in tracking accuracy especially in cases where there is airway deformation and image artefacts.

Algorithms↗

Excision of bronchogenic cysts in children using an ultrathin fibreoptic bronchoscope.

PURPOSE: We report the use of an ultrathin fibreoptic bronchoscope (Olympus N20: external diameter: 2.2 mm) as the means of airway endoscopic monitoring during anaesthesia for the excision of mediastinal bronchogenic cysts in two young children. CLINICAL FEATURES: The first, a four-month old boy, presented with stridor and wheezing due to a subcarinal bronchogenic cyst compressing the two main bronchi. The second, an eight-day-old girl whose trachea was intubated, presented with respiratory noise in relation to a bronchogenic cyst compressing the end of the trachea. In both cases, airway endoscopy was performed during anaesthesia with the ultra thin fibreoptic bronchoscope. Endoscopic monitoring allowed, first, a good evaluation of the degree of cyst compression on the airways. Second, the endotracheal tube could be positioned or repositioned with precision in order to avoid severe compression or spilling of liquid into the airways and to allow protection of the suture. Finally, video transmission helped the surgeon to visualize the surgical repair from the inside. CONCLUSION: When added to the classical monitoring using SpO2, PETCO2 and airway pressure, peroperative endoscopic control provides complementary information which can help to detect possible complications more rapidly. This technique could be extended to all airway surgery on very young children.

Bronchogenic Cyst↗