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At least 253 records · Page 14Linked to original sources

Hepatic actinomycosis with portal vein thrombosis mimicking hepatocellular carcinoma: a case report.

A fatal case of hepatic actinomycosis with portal vein thrombosis is reported. The diagnosis of actinomycosis was delayed because of its rarity in Taiwan. This 63-year-old man was admitted due to body weight loss and poor appetite. No fever was noted before admission. Liver biochemical test showed a decreased serum albumin level with elevated serum levels of globulin and alkaline phosphatase. He was not a hepatitis B carrier and his serum level of alfafetoprotein was within normal range. Image studies (abdominal sonography and computed tomography) showed a hepatic mass over the medial segment of the left lobe with involvement of right lobe of the liver. Main portal vein thrombosis was also seen. Because of profound cachexia, he died of aspiration pneumonia and disseminated intravascular coagulation on the 11th day after admission. An autopsy revealed hepatic actinomycosis. High index of suspicion for early diagnosis and treatment is emphasized.

Actinomycosis↗

Thoracic actinomycosis: an unusual childhood infection.

I have reported a rare case of thoracic actinomycosis in a child with a chest wall mass and pneumonic infiltrate. This case emphasizes the possibility of actinomycosis occurring in a well child with no previous dental problems, chronic lung disease, loss of consciousness, or immunocompromised status. The findings on thoracic computed tomography contributed to the early consideration of actinomycosis in the differential diagnosis.

Actinomycosis↗

Pulmonary actinomycosis. Case report.

Pulmonary actinomycosis. Case report. Pulmonary actinomycosis is a rare infectious disease. The major difficulty is mainly the diagnosis. A high dose of suspicion is required in each intrathoracic process showing malignant behaviour, despite benign histology. Especially if the process extends through normal tissue planes, actinomycosis should be suspected. The therapy of choice should consist in high dose of antibiotics for several months, occasionally followed by surgery. Often though, surgery is the first treatment because of the unability to differentiate the lesion from malignant tumor. Surgery should always be followed by long term antibiotic therapy.

Actinomycosis↗

[Actinomycosis of the tonsils with a pseudotumoral presentation: a clinical case].

A case of actinomycosis of the tonsils with a neoplasm-like clinical presentation is presented. Tonsillectomy confirmed the diagnosis and the patient's evolution was favorable after postoperative antibiotic therapy. The scant literature on cervicofacial actinomycosis is reviewed. These processes often are confused with neoplasms, as in our case, or with mandibular osteomyelitis. Treatment is surgery and prolonged antibiotic administration. Actinomycosis should be considered in the differential diagnosis of cervicofacial masses, particularly when the biopsy is negative for carcinoma.

Actinomycosis, Cervicofacial↗

Hepatic actinomycosis infiltrating the diaphragm and right lung.

Hepatic actinomycosis is a rare infectious disease caused by an anaerobic gram-positive bacterium of the genus Actinomyces. Herein, we describe an unusual case of hepatic actinomycosis involving the diaphragm and right lung. A 41-yr-old man was admitted to Wakayama Medical School Hospital presenting with right back pain and cough. Computed tomography and magnetic resonance image revealed a 5 x 10 cm tumor in the anterior superior segment of the liver, which extended to the diaphragm and right lung. Angiography demonstrated a hypervascular tumor and the enlarged right inferior phrenic artery feeding around the tumor. The patient underwent a hepatectomy with partial resections of the diaphragm and the right middle pulmonary lobe. Microscopically, the specimen showed sulfur granules and was positive for Gram stain and Grocott stain and negative for Ziehl-Neelsen stain. These findings were consistent with actinomycosis of the liver. His postoperative course was uneventful and no recurrence was observed 1 yr postoperatively. Although there are at least 36 well-documented cases until 1993, no other report has been found infiltrating the diaphragm and lung.

Actinomycosis↗

Bilateral tubo-ovarian actinomycosis in the presence of an intrauterine device: a case report.

An uncommon case of actinomycosis found in bilateral tubo-ovarian abscess is presented. Preoperatively, bilateral ovarian tumors were initially suspected by pelvic examination and ultrasonography. The patient received total abdominal hysterectomy and bilateral salpingo-oophorectomy. The initial pathology frozen section report showed abscess without evidence of malignancy. The final pathological finding revealed actinomycosis in bilateral tubo-ovarian abscess. In addition, an intrauterine contraceptive device, Copper-T, was found in the uterine cavity. The radiologic findings, gross pathological feature, histopathological pictures and treatment of pelvic actinomycosis are discussed, with review of the literature in English.

Actinomycosis↗

Pulmonary actinomycosis: surgical considerations.

Pulmonary actinomycosis is a rare disease. Of 2,247 patients presenting with a radiological pulmonary opacity, 13 (0.6%) were identified with pulmonary actinomycosis in a 13 year period. Twelve of the 13 patients underwent thoracotomy and one had clinical diagnosis and subsequent medical treatment alone. Neither mortality nor major complications were observed. One patient had recurrent disease after surgery. The other surgical patients are well and free from disease at a minimum 6 month follow-up. Diagnosis of actinomycosis is frequently difficult because it often infects pre-existing cavitary disease in the lung. As a consequence, the infection may progress to stages which will not respond to medical treatment alone. Surgery then provides the best method to achieve diagnosis and ultimate treatment.

Actinomycosis↗

[Pathogenesis of abdominal actinomycosis].

According to the author's findings in 80 of 125 patients under observation the development of abdominal actinomycosis was related with inflammation in the appendicular process, in 65 patients the former starting after appendectomy. In examination of 100 patients with diagnosis of acute appendicitis actinomycosis of the ileocecal region was diagnosed in 5 patients. Actinomycosis was spreading from the ileocecal region by contact in retroperitoneal cellular tissue in 23 cases, in the left iliac region--in 12, in the lesser pelvis--in 8.

Abdomen↗

[Therapeutic effectiveness of ristomycin in the visceral form of actinomycosis (experimental research)].

Therapeutic efficacy of ristomycin in visceral actinomycosis, a severe disease difficult for diagnosis requiring long-term complex therapy was studied on 24 rabbits. The animals were divided into 4 groups. A model of thoracal actinomycosis was developed. 7 rabbits were treated with ristomycin. The other 7 rabbits were treated with ristomycin in combination with actinolysate, a specific immune preparation. 5 rabbits were treated with actinolysate alone and the other 5 rabbits received no treatment. alone and especially in combination with actinolysate was an efficient therapeutic agent for treatment of severe visceral actinomycosis. This allowed to recommend ristomycin for clinical trials in treatment of the disease.

Actinomycetales Infections↗

Rapid diagnosis of actinomycosis by thin-needle aspiration biopsy.

Actinomycosis was diagnosed in three cases by the use of thin-needle aspiration biopsy technic. Aspiration was utilized for morphologic studies and collection of material for microbiologic isolation. The critical histologic features of sulfur granules remain intact with aspiration technic. Thin-needle aspiration biopsy is a safe, simple, and rapid technic employed in the diagnosis of neoplastic disease. The use of this technic in the diagnosis of actinomycosis is demonstrated in this report.

Actinomycosis↗

Actinomycosis in fine needle aspiration cytology.

Four cases of actinomycosis were diagnosed by fine needle aspiration (FNA) cytology and eight more cases were detected during a review of FNA smears reported as inflammatory. The age of these 12 cases ranged from 20 to 61 years with a median of 35 years. The male to female ratio was 3:1. The common regions of involvement were cervicofacial in seven cases (58.3%), thoracic in three (25.0%) and abdominal in two (16.7%). Four of the seven cervicofacial cases presented with intra-oral masses; the thoracic lesions were pulmonary in location, and the abdominal lesions presented as bowel masses. The possibility of actinomycosis was not considered clinically in any case. The main reason for missed cytodiagnosis in two thirds of the cases appeared to be observer error. It is suggested that when the aspiration smear from a mass is found to be an inflammatory exudate rich in neutrophils, special efforts must be made to look for this microorganism.

Abdomen↗

Scalp actinomycosis mimicking soft tissue mass.

Actinomycosis is a rare, subacute or chronic bacterial infection, characterized by localized swelling with suppuration, abscess formation, tissue fibrosis, and draining sinuses. It is caused by gram-positive, pleomorphic non-spore-forming, non-acid-fast anaerobic or microaerophilic bacilli of the genus Actinomyces. In humans, actinomyces are often normally found in the oral cavity, the gastrointestinal tract and the female genital tract. Infections of the oral and cervicofacial regions are the most commonly reported cases. We present a case of subcutaneous actinomycosis, localized at the upper segment of the posterior neck space, with scalp involvement.

Actinomycosis↗

Actinomycosis: CT findings in six patients.

Actinomycosis is an uncommon disease with clinical and radiographic findings that overlap those of other inflammatory and neoplastic conditions. A retrospective review of CT scans in six proved cases revealed a spectrum of findings, including soft-tissue mass with various degrees of infiltration and abscess formation. Administration of IV contrast material was helpful in defining the loculations of the abscess in two cases. Areas of involvement included the neck (two cases), liver (one case), abdominal wall (one case), thorax (one case) and kidney and retroperitoneum (one case). CT findings of a soft-tissue mass in the neck, lungs, or abdomen, with or without a draining sinus or fistula, raise the possibility of actinomycosis in patients with clinical findings that suggest a subacute or chronic inflammatory process.

Actinomycosis↗

Actinomycosis of the face and neck.

Cervical actinomycosis is a rare condition. During the last six years, five patients were hospitalized in our department, suffering from swelling in the region of the face and neck that was identified bacteriologically as Actinomyces israelii. Soft tumors of the head and neck that do not respond to common antibiotic therapy should arouse the suspicion of actinomycosis.

Actinomyces↗

Cervicofacial actinomycosis. Rapid diagnosis by thin-needle aspiration.

Thin-needle aspiration cytology is a well-known minimally invasive technique that is used in the diagnosis of neoplastic disease. The same biopsy technique provides a means for immediate identification of actinomycosis. Aspiration specimens may be used for morphologic studies, as well as for microbiologic isolation. The diagnostic histologic feature of sulfur granules remains intact with this cytologic aspiration technique. This technique is a safe, simple, and rapid means of diagnosing actinomycosis and appears to have value in the diagnosis of other infectious diseases as well.

Actinomycosis, Cervicofacial↗

Actinomycosis in the acquired immunodeficiency syndrome-related complex.

The first case, to our knowledge, of cervicofacial actinomycosis arising in a patient with evidence of infection by the human T-cell lymphotrophic virus type III, the causal agent of the acquired immunodeficiency syndrome, is reported. Clinical uncertainty often exists in cases of actinomycosis due to the relative rarity of the disease, a clinical presentation that is compatible with a host of neoplastic and other infectious disorders, and difficulty in obtaining absolute bacteriologic documentation. Computed tomography was of interest in this case, since the radiographic findings could be correlated with pathophysiologic changes characteristic of this uncommon infection.

AIDS-Related Complex↗

Actinomycosis otitis media.

Infection of the middle ear and mastoid by actinomycosis is uncommon. We report the 21st case in the English literature. Actinomycosis otitis media is characterized by an indolent course but may be fatal. Multiple recurrences after standard antibiotic therapy are common. Effective treatment consists of surgery and penicillin for several months.

Actinomycosis↗

Diagnosis of hepatic actinomycosis by fine-needle aspiration.

A 48-yr-old white female with a 20-yr history of intrauterine device use presented with signs and symptoms suggestive of a disseminated neoplasm with a pelvic primary. A definitive diagnosis of disseminated actinomycosis was made on the basis of computed tomography-guided fine-needle aspiration of a liver lesion. Subsequent laparotomy revealed involvement of the endometrium and of the ovaries and uterine tubes bilaterally. This article indicates the usefulness of fine-needle aspiration in the diagnosis of actinomycosis in this case.

Actinomyces↗