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PubMed1990

Young adult offspring of parents with drinking problems: recollections of parents' drinking and its immediate effects.

One hundred and seventy 16- to 35-year-old offspring of parents with drinking problems were recruited from a variety of clinical and community sources and each was interviewed at length using a semi-structured interview. The present paper focuses upon carefully reconstructed recollections of childhood, and presents quantitative information from the whole sample and three briefly described individual examples. Large variances on quantitative measures and very varied qualitative accounts of childhood were evident. The large majority described parental drinking problems which spanned their childhood and adolescent years without interruption and without treatment. Amongst the most frequently recalled effects on life at home were parental moodiness, unreliability, and a tendency to upset or fail to join in with family activities. Amongst negative childhood experiences recalled most frequently were worry and uncertainty, a feeling of family instability, the experience of being caught between the interests of two parents, and the adoption of certain adult roles. Those with mothers with drinking problems scored significantly higher on a scale of negative childhood experiences and mothers with drinking problems were more likely to have drunk regularly at home. Those offspring from families of higher social status estimated their parental problems to have started slightly later in childhood. Qualitative analysis suggested that whether excessive parental drinking is perceived as alien to or integral with family life may have been a neglected variable.

Adaptation, Psychological↗
PubMed2003

[Drinking pattern, problem related drinking, perceived stress, ways of coping, and symptoms of stress of the female university students].

PURPOSE: The purpose of this study was to identify the relationship among problem related drinking, perceived stress, ways of coping, and symptoms of stress of the college women. METHOD: Data was collected by questionnaires from 436 the College Women in S City. It was analyzed using descriptive statistics, Pearson correlation coefficients. RESULT: Three point forty -four of the subject had problem-related drinking, 92.43% were experienced alcohol drinking. The level of perceived stress(M=1.48) showed moderate, and symptoms of stress(M=1.34) showed below. The problem-related drinking showed significant positive correlation with perceived stress(r=.10, p=.03), emotion-oriented coping(r=.13, p=.00), and symptoms of stress(r=.23, p=.03). CONCLUSION: Data from this study suggest that perceived stress, ways of coping, and symptoms of stress are significant influencing factors on problem-related drinking in the Female University Students.

English Abstract↗
PubMed2001

Olanzapine reduces urge to drink after drinking cues and a priming dose of alcohol.

RATIONALE: Haloperidol, a D2 antagonist, has been shown to moderate the effects of alcohol consumption on craving. OBJECTIVE: The present study was designed to determine whether a single 5-mg dose of olanzapine (a D2/5-HT2 antagonist) would influence responses to alcohol cues or an alcohol challenge. It was hypothesized that olanzapine would attenuate cue-elicited urge to drink, attenuate the effects of alcohol consumption on urge to drink, and reduce the rewarding effects of alcohol. METHODS: To test these hypotheses, 26 heavy social drinkers were randomized to receive either 5 mg olanzapine or placebo approximately 8 h before each of two experimental sessions. Participants consumed a moderate dose of alcohol in one experimental session and a non-alcohol control beverage in another session. RESULTS: Results indicated that mere exposure to alcohol cues and consumption of alcohol increased urge to drink and that olanzapine attenuated these effects. Results also indicated that alcohol increased subjective stimulation and high while olanzapine did not moderate these effects. CONCLUSIONS: These results suggest that olanzapine did not influence the rewarding effects of alcohol but did attenuate the effects of alcohol cues and an alcohol challenge on urge to drink.

Adult↗
PubMed1987

Postingestional modulation of drinking induced in rats by angiotensin II: intragastric infusion and sham drinking studies.

The dipsogenic potency of angiotensin II (ANGII, 200 micrograms/kg, SC) was examined after the removal of various postingestional factors. In the first experiment, rats with intragastric catheters were injected SC with ANGII and allowed water to drink. During the induced drinking, either NaCl (1.5 M) or water was injected into the stomach via the catheter at a rate of 0.1 ml for each ml water ingested orally. The water intake was identical in the two conditions. In a second experiment, rats, fitted with gastric fistulas, were administered ANGII and subsequent water intake with fistulas open was compared to that occurring with the fistulas closed. Rats drank more water during the first trial with fistulas open than with fistulas closed. Water intake during subsequent trials with an open fistula rose above that observed on the first trial. In a third experiment, rats with gastric fistulas were offered 0.15 M NaCl to drink. Intake was greater when the fistula was open than when it was closed. Intake of 0.15 M NaCl increased during the second trial with fistula open. Rats drank more 0.15 M NaCl during the first trial with an open fistula in Experiment 3 than those rats given water to drink on their first trial with fistula open in Experiment 2. These data suggest both oropharyngeal and postingestional factors interact in the control of ANGII-induced fluid intake.

Angiotensin II↗
PubMed1990

Principal components analysis of the inventory of drinking situations: empirical categories of drinking by alcoholics.

Male alcoholics (n = 336) were given the Inventory of Drinking Situations (IDS), a 100-item questionnaire that asks subjects to rate the frequency with which they drank in various situations during the previous year. A principal components analysis of the responses suggests there are three major categories of situations in which alcoholics are likely to drink: negative affect states, positive affect states combined with social cues to drink, and attempts to test one's ability to control one's drinking. These categories are compared with recent empirical attempts to define categories of alcohol and smoking relapse.

Adult↗
PubMed1986

Effect of pimozide on home cage ethanol drinking in the rat: dependence on drinking session length.

A stimulus-fading procedure was used to initiate ethanol drinking in free-feeding Long Evans rats. During daily half-hour drinking sessions in the home cage, a combination of sucrose and ethanol was first presented to the rats; gradually the sucrose concentration was reduced and the ethanol concentration increased until after 7 weeks the rats were drinking 10% ethanol with no sucrose. After stabilization of intake, either pimozide (PIM, 0.25, 0.50 and 1.00 mg/kg) was injected 4 h before drinking sessions or (d)-amphetamine (DEX, 0.25 and 0.50 mg/kg) was injected 15 min before sessions. The 0.50 and 1.00 mg/kg PIM doses and the 0.50 DEX dose significantly reduced intake compared to vehicle injections. In the second part of the experiment, the rats were given 24-h access to 10% ethanol and water in a two-bottle choice procedure. In this condition, 0.50 mg/kg PIM failed to reduce intake compared to vehicle. The critical difference between the two procedures seems to be that with the 30-min sessions, PIM injections were timed to have their maximal effect during testing. With 24-h sessions, decreases in intake produced by PIM could have been compensated for by increases after the drug had worn off. The hypothesis that dopamine is necessary for ethanol reinforcement receives support from the PIM effect on the 30-min sessions. The DEX effect extends the generality of our previous finding that DEX reduces ethanol-reinforced lever pressing in free-feeding rats.

Alcohol Drinking↗
PubMed2003

Ethanol effects on local cerebral glucose utilization in high-alcohol-drinking and low-alcohol-drinking rats.

Divergent ethanol-drinking behavior in rats selectively bred for high- or low-ethanol-drinking behavior could be related to differences in the sensitivity of the CNS to ethanol. In the current study, we examined the effects of acute (i.e., single injection) ethanol administration on local cerebral glucose utilization (LCGU) within selected brain regions of high-alcohol-drinking (HAD) and low-alcohol-drinking (LAD) rats. Adult, male, HAD and LAD rats from replicate line 2 were injected intraperitoneally with saline, or ethanol, at doses of 0.25 g/kg or 1.0 g/kg, during their dark cycle; 10 min later, [14C]-2-deoxyglucose ([14C]-2-DG; 125 microCi/kg) was injected into the femoral vein. Timed arterial blood samples were collected over 45 min and assayed for plasma glucose, ethanol, and [14C]-2-DG levels. Rats were then decapitated, and their brains were quickly extracted and frozen in isopentane at -50 degrees C. Coronal brain sections were prepared and apposed to x-ray film for 2 days, and image densities were determined by using quantitative autoradiography. Data were collected from several key limbic (nucleus accumbens, ventral tegmental area, olfactory tubercle, amygdala, hippocampus, ventral pallidum, and septum), basal ganglia, cortical (medial prefrontal, frontal, parietal, temporal, occipital, entorhinal, piriform, and cingulate), and subcortical (thalamus, habenula, and superior colliculus) structures. After administration of both low (0.25 g/kg) and moderate (1.0 g/kg) doses of ethanol, LCGU values were lower, relative to those for saline controls, in several CNS regions (lateral septum; posterior cingulate, frontal, parietal, and temporal cortices; dorsomedial striatum; and dorsomedial thalamus) of LAD but not HAD rats. These findings may indicate that certain CNS regions of LAD-2 rats are more sensitive than regions of HAD-2 rats to the effects of low-to-intermediate doses of ethanol.

Alcohol Drinking↗
PubMed2000

Using daily reports to measure drinking and drinking patterns.

Daily measurements of drinking are used to measure alcohol consumption, validate retrospective questionnaires, and examine associations between drinking and other behaviors. The advantages of using daily reports include reducing retrospective biases and forgetting of drinking occasions; disadvantages include increased costs and potential for reactivity. Methodological issues to consider in using daily reports include reporting method (written, telephone, electronic), reporting interval, data collection period, respondent attrition, and missing data. Compared to retrospective reports, daily reports result in more reported drinking occasions but similar average quantity consumed, and correlations between retrospective and daily measures are generally high. The utility of daily reports depends on the research question and the purpose of the measurements.

Alcohol Drinking↗
PubMed1995

New beverages, new drinking contexts? Signs of modernization in Finnish drinking habits from 1984 to 1992, compared with trends in the European Community.

The dynamics of change in drinking patterns is discussed using the data from the drinking habits surveys conducted in Finland in 1984 and 1992. The results are compared with a respective analysis on the EU countries from 1988 by Hupkens, Knibbe & Drop (1993). The analysis is based on changes in beverage preferences. In the Finnish case, both wine and mild beer appear as new beverages, gaining popularity in the late 1980s. For beer, both the elites and the population at large were involved in that process. For wine, the interest in the new beverage was stronger among the elites. There were notable gender differences in adopting the new beverage. Some of the differences were related to the older cultural patterns of wine as a woman's drink and beer as a male beverage. The results also point to difficulties in analysing the dynamics of change on the basis of cross-sectional data, as was done in the earlier analysis on the EC countries. The Finnish data shows that even the inter-group dynamics of drinking patterns may change over a relatively short period of time.

Adolescent↗
PubMedDate not supplied

Type of alcoholic beverage and high-risk drinking: how risky is beer drinking in Korea?

AIMS: To examine the association of beverage type with high-risk drinking in Korea. METHODS: Data were analysed from the Korea's 1997 behavioural risk factor surveillance system survey collected by a stratified random sampling method (n = 1045). After alcohol consumption per drinking day was categorized into three risk levels for short-term or 'acute' harm on the basis of the World Health Organization's guidelines, logistic regression analysis adjusting for socio-demographic factors was performed for each beverage type. RESULTS: Using beer drinkers as the reference, those who drank soju (the most widely consumed traditional beverage in Korea) showed an adjusted odds ratio (OR) of 3.62 [95% confidence interval (CI) = 2.28-5.76] for high and very high risk from drinking and those who drank spirits had adjusted OR of 10.65 (95%CI = 4.32-26.27). CONCLUSIONS: In Korea, unlike in many western countries, beer is not the highest risk beverage. The relatively high price of beer in Korea is likely to be one influence. It is concluded that country-specific differences are important in studies on associations between alcoholic beverage types and high risk drinking.

Adult↗
PubMed1992

The associations of alcohol drinking and drinking cessation to measures of the immune system in middle-aged men.

To estimate the association between the immunologic responses of the cell-mediated and humoral systems and alcohol drinking, we used data from the Vietnam Experience Study conducted by the Centers for Disease Control. That study, conducted from 1985 to 1986, was based on a random sample of 4462 male, Vietnam-era, U.S. veterans. By using linear regression, we evaluated how (1) the number of alcoholic drinks the subjects consumed per month and (2) the drinking cessation of certain subjects were associated with their relative and absolute T, B, CD4, and CD8 lymphocyte counts and immunoglobulin A (IgA), IgM, and IgG levels. We used geometric means and percentage differences in geometric means of immune status to measure the associations and adjusted these values to account for the effect of covariates. The results indicated that measures of immune status differed among the drinking categories and that, generally, the differences changed after adjustment for covariates. These differences consisted, as alcohol consumption increased, of higher IgA and IgM levels, relative T and CD4 lymphocytes, and the ratio of CD4 to CD8 cells, and of lower IgG levels, relative B and CD8 lymphocytes, absolute lymphocyte, and lymphocyte subset counts after adjusting for other covariates. Among former drinkers, we found no clear-cut pattern in measures of immunity for a few years after cessation and then found that values of former drinkers tended to return toward values of nondrinkers as they continued to abstain.

Adult↗
PubMed1995

The Obsessive Compulsive Drinking Scale: a self-rated instrument for the quantification of thoughts about alcohol and drinking behavior.

It has been suggested that a crucial dimension of alcohol "craving" includes the concept of both obsessive thoughts about alcohol use and compulsive behaviors toward drinking. An interview-based rating scale, the Yale-Brown Obsessive Compulsive Scale-heavy drinkers (YBOCS-hd), has been found useful in quantifying this concept in alcohol-dependent individuals. A self-rating scale, the Obsessive Compulsive Drinking Scale (OCDS) has been developed by us as a modification of the YBOCS-hd. The YBOCS-hd showed excellent interrater reliability in our hands. The correlation between the YBOCS-hd and the OCDS total scores obtained on 60 alcohol-dependent individuals was 0.83. The test-retest correlation for the OCDS total score was 0.96, and the obsessive and compulsive subscales test-retest correlations were 0.94 and 0.86, respectively. The internal consistency of the items in the OCDS was high (0.86) and did not improve significantly with removal of individual items. The shared variance between the OCDS scores and alcohol consumption during the period of evaluation was only approximately 20%, indicating that the dimension measured by the scale was somewhat independent of actual drinking. As such, it might act as an independent measure of the "state of illness" for alcohol-dependent individuals. When used during a prospective 12-week treatment research study, initial results indicate that the OCDS seems to validly measure a dimension of alcohol dependence, because it decreased from baseline during alcohol reduction and increased in relationship to relapse drinking.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1998

Long-term change in underage drinking and impaired driving after the establishment of drinking age laws in New York State.

This study depicts the long-term change in youths' alcohol use and impaired driving behaviors associated with the establishment of the drinking age laws. Five telephone surveys were conducted with youths aged 16 to 24 in 10 sampled New York State counties in 1982, 1983, 1985, 1986, and 1996. Analysis of the self-reported data showed that, 10 years after the enactment of the 21 drinking age law, alcohol use among 18-, 19-, and 20-year-olds decreased by up to 58%. Alcohol purchase rates of 19- and 20-year-olds were reduced by approximately 70% from 1985 to 1996. Although impaired driving rates declined over the survey years for each age group, approximately 25% of all underage respondents in 1996 reported that they had ridden in a vehicle with an impaired driver. Findings from this research indicate that alcohol purchase, alcohol use, and impaired driving have declined among the targeted youth groups as a result of the 21 drinking age law. However, continued efforts need to focus on both underage drinking and impaired driving/riding with impaired drivers, because they remain serious public health risks among the youth population.

Accidents, Traffic↗
PubMed2006

Relationship between level of consumption and harms in assessing drink cut-points for alcohol research: Commentary on "Many college freshmen drink at levels far beyond the binge threshold" by white et Al.

In this commentary, we describe the use of a 5/4 drink summary measure of heavy episodic alcohol consumption, or "binge" drinking, in survey research and its usefulness for preventing negative alcohol-related consequences. Data from 4 nationally representative surveys of more than 50,000 college students are utilized to examine the utility of this measure in comparison with alternative cut-points. Our analysis demonstrates that while higher drink threshold measures incrementally improve the ability to identify correctly students who experience harms or who meet DSM-IV diagnostic criteria of alcohol abuse and dependence, they capture only a small proportion of those college students experiencing harms. We conclude that the selection of a measurement tool should be consistent with the purpose for which it is to be used. The 5/4 measure of binge drinking provides a valuable means for understanding and preventing alcohol-related harms in a college population and can be utilized as a screen to identify students who may need additional clinical assessment for intervention.

Alcohol Drinking↗
PubMed1996

Effect of drink flavor and NaCL on voluntary drinking and hydration in boys exercising in the heat.

This study was intended to assess the influence of drink flavor and composition on voluntary drinking and hydration status in children exercising intermittently at 35 +/- 1 degrees C and 45-50% relative humidity. Twelve boys (9-12 yr) performed three 3-h identical sessions (four 20-min cycling bouts at 50% maximal O2 uptake followed by 25-min rest). One of three beverages (chilled to 8-10 degrees C) was assigned to each session in a Latin-square sequence: unflavored water (W), grape-flavored water (FW), and grape-flavored water plus 6% carbohydrate and 18 mmol/l NaCl (CNa). Drinking was ad libitum. Body weight, heart rate, rectal and skin temperatures, and thirst and stomach fullness perceptions were monitored periodically. Total intake was 610, 882, and 1,157 g in W, FW, and CNa, respectively (CNa-W and CNa-FW; P < 0.05). Hypohydration was observed with W (-0.65% body wt) and FW (-0.32% body wt), but drinking CNa resulted in slight overhydration (+0.47% body wt, CNa-W, CNa-FW; P < 0.05). Other physiological and all perceptual variables were insignificantly different among trails. In conclusion, while flavoring of water reduces children's voluntary dehydration, further addition of 6% carbohydrates and 18 mmol/l NaCl prevents it altogether.

Body Temperature Regulation↗
PubMed2004

Gender roles, family, and drinking: women at the crossroad of drinking cultures.

During the postwar era, extensive changes in family structure and gender roles have occurred in Western countries. The aim of this study was to see if processes of change and convergence in gender roles have led to new drinking patterns among Swedish women. Data were collected from a survey conducted in 1979 and replicated in 2003. For this study, data on aspects of drinking patterns and problems were combined with demographics and indicators of social situation. For one of the drinking pattern indicators, the assumption of convergence between the sexes was confirmed. Generally, though, differences in drinking patterns are at hand among both women and men in the same direction. Also, social background factors and demographics have weaker explanatory power today compared to the late 1970s.

Alcohol Drinking↗
PubMed2004

Drinking like a man: the paradox of excessive drinking for seventeenth-century dutch youths.

In the early modern period, drinking alcohol was an integral part of Dutch social and cultural life. Toast were made to the health of unborn babies, for job nominations, and at funerals. Young people started to consume alcohol at an early age. However, within this culture they had to learn how to drink in moderation. Excessive drinking was not only a cardinal sin, it was also a paradox in the realm of gender. For males, the act of getting drunk and losing control was a flaw on their masculinity. They in fact became like women who were believed to be incapable of controlling their mind and body. On the other hand, the ability to drink great quantities of alcohol symbolized an age-old form of masculinity. Imbibing in "wine, women, and song" were liminal rites in becoming men and how young men demarcated themselves from being boys.

Adolescent↗
PubMed2001

Finding the meanings of college drinking: an analysis of fraternity drinking stories.

College drinking has traditionally been studied from a public health perspective that attempts to quantify behavior as a means toward description, explanation, and intervention. This article offers a critical and cultural approach to understanding the meanings and functions of high-risk drinking and the ways in which those meanings are reproduced within the culture. Data were collected via an ethnographic study of fraternity members at a large midwestern university to explore the communication of excessive drinking norms. Viewed from various narrative and structural theories, the study examines collected drinking stories as a source for analyzing the construction of meanings surrounding drunkenness for the fraternity subculture. Five themes emerged as functions of drunkenness for the culture. Implications for prevention are discussed.

Adult↗