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At least 235 records · Page 13Linked to original sources

New technology for the design of advanced ultrasonic transducers for high-power applications.

A new high-frequency ultrasonic transducer for wire bonding has been conceived, designed, prototyped and tested. In the design phase an advanced approach was used and established. The method is based on the two basic principles of modularity and iteration. The transducer is decomposed to its elementary components. For each component an initial design is obtained with finite elements method (FEM) simulations. The simulated ultrasonic modules are then built and characterized experimentally through laser-interferometry measurements and electrical resonance spectra. The comparison of simulation results with experimental data allows the parameters of FEM models to be iteratively adjusted and optimized. The achieved FEM simulations exhibit a remarkably high-predictive potential and allow full control on the vibration behavior of the ultrasonic modules and of the whole transducer. The new transducer is fixed on the wire bonder with a flange whose special geometry was calculated by means of FEM simulations. This flange allows the converter to be attached on the wire bonder not only in longitudinal nodes but also in radial nodes of the ultrasonic field excited in the horn. This leads to a nearly complete decoupling of the transducer to the wire bonder, which has not been previously obtained. The new approach to mount ultrasonic transducers on a welding-device is of major importance not only for wire bonding but also for all high-power ultrasound applications and has been patented.

Computer Simulation↗

Intraoperative epicardial echocardiography: early experience with a newly developed small surgical transducer.

To test the feasibility of performing intraoperative echocardiography with a specially designed epicardial transducer, 20 adult patients were studied. All patients were undergoing coronary bypass surgery and had structurally normal intracardiac anatomy. The surgical transducer has 48 elements and a size at the tip of 10 x 12 x 5 mm. The scan plane has been set at 90 degrees to the cable axis to allow scanning from lateral positions. The terminal 10 cm of the cable has been reinforced to act as a malleable and steerable handle. Good quality images were obtained with the new transducer, and many different imaging planes were identified compared to imaging with the standard transducers. These include the right ventricular apex, the right and left lateral aspects of the heart, the aortic arch, and the pulmonary artery and its branches. The limitation of the probe was the difficulty in obtaining left ventricular apical views because of ventricular arrhythmias sustained when the transducer was placed between the left ventricular apex and the diaphragm. We conclude that this new transducer has a promising future in the application of intraoperative epicardial echocardiography.

Adult↗

Ultrasonic mixing in microfluidic channels using integrated transducers.

This paper presents a microfluidic mixer that uses acoustic stirring created by ultrasonic waves. The ultrasound is introduced into the channel by integrated piezoelectric transducers. The transducers are made of a zinc oxide thin film, which is deposited on the bottom surface of a quartz substrate. The poly(dimethylsiloxane) channel is aligned to the transducers on the top surface of the substrate. The transducers are designed for operation around 450 MHz. The main mechanism of the mixing is the acoustic stirring of the fluid perpendicular to the flow direction. The radiation pressure that is generated by the transducer causes the stirring inside the microfluidic channel. The performance of the mixer is characterized by mixing phenolphthalein solution and sodium hydroxide dissolved in ethyl alcohol. Flow rates on the order of 1-100 microL/min are used. The transducers are driven by 1.2 V(rms) sinusoidal voltages at 450 MHz.

Microfluidics↗

Comparison of transducers and intraoral placement options for measuring lingua-palatal contact pressure during speech.

Two studies were completed that focused on instrumentation and procedural issues associated with measurement of lingua-palatal contact pressure (LPCP) during speech. In the first experiment, physical features and response characteristics of 2 miniature pressure transducers (Entran EPI-BO and Precision Measurement 60S) were evaluated to identify a transducer suitable for measuring LPCP during speech. The 2 transducers were comparable in terms of physical dimensions and most response characteristics. However, the Entran device was less affected by air temperature fluctuations, making it the more attractive option for speech LPCP measurement. In a second experiment, 3 methods of placing the Entran device in the mouth were compared. The 3 adhesion methods evaluated were (a) taping a transducer to the hard palate, (b) surface mounting on a mold of the palate, and (c) flush mounting on a mold of the palate. Directly taping the transducer to the alveolar ridge was the least acceptable option, as it resulted in changes in other aspects of speech production (consonant duration and centroid frequency of the burst/frication) suggesting that articulation was unduly altered. Direct taping was also rated as least acceptable by the speakers. Surface and flush mounting resulted in fewer changes in speech aerodynamic and acoustic parameters of /t/ and/s/ compared to the tape condition. Listener ratings also indicated less articulatory disturbance in the surface and flush mounting conditions compared to the tape condition. Surface mounting was technically easier than flush mounting and it allows for rapid repositioning of the transducer if needed.

Acoustic Stimulation↗

"Hands-Free" continuous transthoracic monitoring of pericardiocentesis using a novel ultrasound transducer.

BACKGROUND: Pericardiocentesis can be monitored with a hand-held transducer. The purpose of this study was to assess the feasibility of monitoring pericardiocentesis using a novel ultrasound transducer, which can be attached to the chest wall, developed in our laboratory (CONTISON). METHODS: We studied nine patients with large pericardial effusions. The 2.5-MHz transducer is spherical in its distal part and mounted in an external housing to permit steering in 360 degrees. The external housing is attached to the chest wall using an adhesive patch. The CONTISON transducer was placed at the cardiac apex and an apical four-chamber view obtained. Pericardiocentesis was performed from the subcostal position. The pericardial effusion was continuously imaged. Mitral inflow velocity signals were recorded before and after pericardiocentesis. When fluid was first obtained, 50 mL of fluid were discarded after which 5 mL of agitated saline was injected through the needle. RESULTS: In the first patient the pericardiocentesis needle was seen in the left ventricular cavity. Saline injection produced a contrast effect in the left ventricle. The needle was gradually withdrawn until contrast was seen in the pericardial sac. A total of 1100 mL was removed without further complications. The second patient had clear fluid followed by blood stained aspirate. The echocardiogram revealed gradual appearance of granular echoes within the pericardial sac, suggestive of intrapericardial clot that was subsequently surgically evacuated. In the remaining seven patients, agitated saline produced a contrast effect in the pericardial sac indicative of proper needle position. Mitral flow velocity paradoxus was noted in five patients, and it resolved after pericardiocentesis in four patients. No adjustment of the transducer was required. CONCLUSION: The CONTISON transducer permitted continuous monitoring of pericardiocentesis. This technique could potentially facilitate pericardiocentesis.

Adult↗

[Laboratory experiment studies on quantitative blood flow measurement with the continuous-wave ultrasound Doppler procedure: I. Transducer evaluation].

Cw-Doppler transducers designed for volume blood flow measurement were evaluated experimentally. Both sensitivity plotting using a ball point reflector and comparative volume flow measurement on a flow-rig using EMF as reference method evidenced unequal sensitivity along the transducer. With increasing distance to the transducer the longer axis of the oval sound field assumed an orientation perpendicular to the longer axis of the active transducer surface. Sensitivity decreased from the centre of the sound field to its periphery. Differences of more than 2 mm between the length of the transducer and the diameter of the latex tube resulted in over- or underestimations of volume flow. Underestimations found with transducers longer than the tube diameter were interpreted as resulting from the increased contribution of stable echoes to the signal.

Blood Flow Velocity↗

Influence of transducer frequency on Doppler microemboli signals in an in vivo model.

The purpose of this study was the comparison between 1 MHz and 2 MHz transducers in the detection of Doppler microembolic signals (MES). Intraoperative monitoring was performed over the arterial tubing of the extracorporal circulation circuit in 10 patients undergoing coronary artery bypass surgery, using a pulsed ultrasound machine (DWL X-4). 1 MHz and 2 MHz probes were mounted to insonate sequential tubing segments and all monitoring sessions saved on digital audio tapes (DAT). MES counts and intensity as detected by each probe were subsequently evaluated. Specific interobserver agreement was assessed using Cohen's kappa-statistic. Time delay in the appearance of MES between the transducers was minimal (0-0.1 msec). A total of 5293 (64%) MES were detected by both probes, 2796 (33.8%) only with the 1 MHz and 181 (2.2%) only with the 2 MHz probe. Significant differences in MES intensity were evident when comparing the 1 MHz to the 2 MHz transducer (16.4 +/- 0.1 and 11 +/- 0.1 dB with the 1 MHz and 2 MHz transducers respectively, p < 0.0001). Specific interobserver agreement was satisfactory (k = 0.78). Use of 1 MHz instead of 2 MHz transducers increases the yield of embolus detection in vitro. Evaluation of the applicability and performance of this transducer in clinical settings is warranted.

Catheters, Indwelling↗

Use of a fibre-optic hydrophone in measuring acoustic parameters of high power hyperthermia transducers.

A fibre-optic hydrophone consisting of a polarisation-maintaining fibre carrying light from a laser source has been used to measure the acoustic output parameters of a single focused hyperthermia transducer and a six-transducer assembly. Beam profiles of the transducers were measured using the fibre-optic hydrophone and the results compared with those obtained using a PVDF hydrophone. The acoustic power output from the hyperthermia transducer was measured using a radiation force balance. It was observed that the root mean square voltage of the fibre-optic hydrophone output is proportional to the square root of the acoustic power up to more than 80 W. It was also observed that, under continuous-wave operation, the fibre optic hydrophone can stand up to very high power (more than 200 W) without being damaged. As its sensing element is the fibre itself, whose diameter is considerably narrower than the width of the ultrasonic beam, it can provide resolution of about 80 microm in beam profile measurement. The fibre is a line sensor and a computer tomographic technique is used to recover the pressure profile from the hydrophone output voltage. In typical clinical operations, the six-transducer assembly is driven with less than 150 W of electrical power input. In such cases, each individual transducer receives less than 25 W of input power and non-linearity and generation of high frequency harmonics at the focus is not a significant problem.

Acoustics↗

A new ultrasonic transducer for improved contrast nonlinear imaging.

Second harmonic imaging has provided significant improvement in contrast detection over fundamental imaging. This improvement is a result of a higher contrast-to-tissue ratio (CTR) achievable at the second harmonic frequency. Nevertheless, the differentiation between contrast and tissue at the second harmonic frequency is still in many situations cumbersome and contrast detection remains nowadays as one of the main challenges, especially in the capillaries. The reduced CTR is mainly caused by the generation of second harmonic energy from nonlinear propagation effects in tissue, which hence obscures the echoes from contrast bubbles. In a previous study, we demonstrated theoretically that the CTR increases with the harmonic number. Therefore the purpose of our study was to increase the CTR by selectively looking to the higher harmonic frequencies. In order to be able to receive these high frequency components (third up to the fifth harmonic), a new ultrasonic phased array transducer has been constructed. The main advantage of the new design is its wide frequency bandwidth. The new array transducer contains two different types of elements arranged in an interleaved pattern (odd and even elements). This design enables separate transmission and reception modes. The odd elements operate at 2.8 MHz and 80% bandwidth, whereas the even elements have a centre frequency of 900 kHz with a bandwidth of 50%. The probe is connected to a Vivid 5 system (GE-Vingmed) and proper software is developed for driving. The total bandwidth of such a transducer is estimated to be more than 150% which enables higher harmonic imaging at an adequate sensitivity and signal to noise ratio compared to standard medical array transducers. We describe in this paper the design and fabrication of the array transducer. Moreover its acoustic properties are measured and its performances for nonlinear contrast imaging are evaluated in vitro and in vivo. The preliminary results demonstrate the advantages of such a transducer design for improved contrast detection.

Acoustics↗

Measuring systolic arterial blood pressure. Possible errors from extension tubes or disposable transducer domes.

The purpose of this study was to evaluate the magnitude of possible error in the measurement of systolic blood pressure if disposable, built-in diaphragm, transducer domes or long extension tubes between the patient and pressure transducer are used. Sinusoidal or arterial pressure patterns were generated with specially designed equipment. With a long extension tube or trapped air bubbles, the resonant frequency of the catheter system was reduced so that the arterial pulse was amplified as it acted on the transducer and, thus, gave an erroneously high systolic pressure measurement. The authors found this error to be as much as 20 mm Hg. Trapped air bubbles, not stopcocks or connections, per se, lead to poor fidelity. The utility of a continuous catheter flush system (Sorenson, Intraflow) to estimate the resonant frequency and degree of damping of a catheter-transducer system is described, as are possibly erroneous conclusions. Given a rough estimate of the resonant frequency of a catheter-transducer system and the magnitude of overshoot in response to a pulse, the authors present a table to predict the magnitude of probable error. These studies confirm the variability and unreliability of static calibration that may occur using some safety diaphragm domes and show that the system frequency response is decreased if air bubbles are trapped between the diaphragms. The authors conclude that regular procedures should be established to evaluate the accuracy of the pressure measuring systems in use, the transducer should be placed as close to the patient as possible, the air bubbles should be assiduously eliminated from the system.

Air↗

Three-dimensional trajectory assessment of an IVUS transducer from single-plane cineangiograms: a phantom study.

The recovery of the three-dimensional (3-D) path of the transducer used during an intravascular ultrasound (IVUS) examination is of primary importance to assess the exact 3-D shape of the vessel under study. Traditionally, the reconstruction is done by simply stacking the images during the pullback, or more recently using biplane angiography to recover the vessel curvature. In this paper, we explain, how single-plane angiography can be used with two projection models, to perform this task. Two types of projection geometry are analyzed: weak-perspective and full-perspective. In weak-perspective projection geometry, the catheter path can be reconstructed without prior transducer depth information. With full-perspective projection geometry, precise depth location of reference points are needed in order to minimize the error of the recovered transducer angle of incidence. The transducer angulation reconstruction is based on the foreshortening effect as seen from the X-ray images. By comparing the measured to the true transducer length, we are able to get its incidence angle. The transducer trajectory is reconstructed by stitching together the different estimated angulations obtained from each image in a cineangiogram sequence. The method is described and validated on two helical vessel phantoms, giving on average a reconstructed path that is less than 2 mm distant from the true path when using full-perspective projection.

Catheterization↗

Piezoelectrically actuated flextensional micromachined ultrasound transducers--I: theory.

This series of two papers considers piezoelectrically actuated flextensional micromachined ultrasound transducers (PAFMUTs) and consists of theory, fabrication, and experimental parts. The theory presented in this paper is developed for an ultrasound transducer application presented in the second part. In the absence of analytical expressions for the equivalent circuit parameters of a flextensional transducer, it is difficult to calculate its optimal parameters and dimensions and difficult to choose suitable materials. The influence of coupling between flexural and extensional deformation and that of coupling between the structure and the acoustic volume on the dynamic response of piezoelectrically actuated flextensional transducer are analyzed using two analytical methods: classical thin (Kirchhoff) plate theory and Mindlin plate theory. Classical thin plate theory and Mindlin plate theory are applied to derive two-dimensional plate equations for the transducer and to calculate the coupled electromechanical field variables such as mechanical displacement and electrical input impedance. In these methods, the variations across the thickness direction vanish by using the bending moments per unit length or stress resultants. Thus, two-dimensional plate equations for a step-wise laminated circular plate are obtained as well as two different solutions to the corresponding systems. An equivalent circuit of the transducer is also obtained from these solutions.

Computer Simulation↗

Transducer design for a portable ultrasound enhanced transdermal drug-delivery system.

For application in a portable transdermal drug-delivery system, novel transducers have been designed to enhance insulin transmission across skin using ultrasound. Previous research has shown transdermal delivery of insulin across skin using commercial sonicators operating at 20 kHz with intensities ranging from 12.5 to 225 mW/cm2. The goal of this research was to design and construct a small, lightweight transducer or array that could operate with a similar frequency and intensity range as a commercial sonicator used in previous transdermal ultrasound insulin experiments, but without the weight and mass of a sonicator probe. To obtain this intensity range, a cymbal transducer design was chosen because of its light, compact structure and low resonance frequency in water. To increase the spatial ultrasound field for drug delivery across skin, two arrays, each comprising of four cymbal transducers, were constructed. The first array, designated the standard array, used four cymbals transducer elements in parallel. A second array (named the stack array) used four cymbal transducers that used stacked piezoelectric discs to drive the titanium flextensional caps. Under similar driving conditions, the standard array produced intensities comparable to those achieved using a commercial sonicator.

Administration, Cutaneous↗

MEMS ultrasonic transducers for the testing of solids.

Arrays of capacitive diaphragm ultrasonic transducers could potentially be used for non-destructive ultrasonic testing and structural monitoring. In this paper, we consider the efficiency of coupling of these transducers to solid media. We show that efficient coupling can be realized by using a silicone coating as a coupling medium. We present the results of experimental characterization of ultrasonic transducers coupled to solids in this way. We show that these transducers can be used with piezoelectric emitting transducers within the range from 1 to 5 MHz, and we demonstrate the use of several transducers as a phased array to determine the direction and distance of an ultrasonic source.

Acoustic Stimulation↗

High-frequency transducers based on integrated piezoelectric thick films for medical imaging.

A screen-printed PZT thick film with a final thickness of about 40 microm was deposited on a porous PZT substrate to obtain an integrated structure for ultrasonic transducer applications. This process makes it possible to decrease the number of steps in the fabrication of high-frequency, single-element transducers. The porous PZT substrates allow high acoustic impedance and attenuation to be obtained, satisfying transducer backing requirements for medical imaging. The piezoelectric thick films deliver high electromechanical performance, comparable to that of standard bulk ceramics (thickness coupling factor over 45%). Based on these structures, high-frequency transducers with a center frequency of about 25 MHz were produced and characterized. As a result, good sensitivity and axial resolution were obtained in comparison with similar transducers integrating a lead titanate (PT) disk as active material. The two transducers were integrated into a high-frequency imaging system, and comparative skin images are shown.

Electrochemistry↗

Noise in pressure transducer readings produced by variations in solar radiation.

Variations in solar radiation can produce noise in readings from gauge pressure transducers when the transducer cable is exposed to direct sunlight. This noise is a result of insolation-induced heating and cooling of the air column in the vent tube of the transducer cable. A controlled experiment was performed to assess the impact of variations in solar radiation on transducer readings. This experiment demonstrated that insolation-induced fluctuations in apparent pressure head can be as large as 0.03 m. The magnitude of these fluctuations is dependent on cable color, the diameter of the vent tube, and the length of the transducer cable. The most effective means of minimizing insolation-induced noise is to use integrated transducer-data logger units that fit within a well. Failure to address this source of noise can introduce considerable uncertainty into analyses of hydraulic tests when the head change is relatively small, as is often the case for tests in highly permeable aquifers or for tests using distant observation wells.

Artifacts↗

Comparison of ultrasound quality assurance phantom measurements from matched and mixed scanner-transducer combinations.

Our goal in this work was to compare the results of common phantom tests made using matched and mixed ultrasound (US) scanner-transducer combinations. Sets of common US quality assurance (QA) measurements were made using matched US scanner-transducer combinations (i.e., transducers purchased for use with a particular scanner), as well as unmatched (mixed) combinations. Measurements of vertical and horizontal distance accuracy, and depth of penetration were performed using three common transducer types. Means, standard deviations, and differences between the mean mix and match measurements divided by the standard deviation (match-mix difference, or MMD), and two-sided, paired t-tests were computed for the groups of mixed and matched measurements. MMDs for vertical and horizontal distance accuracy test results were less than 0.87 in all cases, well below our threshold value of 2.0, which indicates that a significant difference exists. MMDs for the depth of penetration measurements were less than 1.50, again below the threshold value. These results suggest that all of the mixed and matched data sets were very similar. The more sensitive t-tests indicate statistically significant differences in only 2 of the 18 pairs of data sets. In conclusion, this study suggests that QA measurements generated by mixed or matched scanner-transducer combinations are very comparable. The ability to obtain QA phantom test data from mixed scanner-transducer combinations reduces the time required for US QA testing.

Calibration↗

Analysis of the sandwich piezoelectric ultrasonic transducer in coupled vibration.

The coupled vibration of the sandwich piezoelectric transducer with a large cross-section is analyzed using an approximate analytic method. The resonance frequency equations of the transducer are derived and the effect of the geometrical dimensions on the resonance frequency is studied. It is illustrated that when the radial vibration in the transducer is considered, the vibration of the sandwich transducer becomes more complex. Apart from the longitudinal resonance frequency, the radial resonance frequency can also be obtained. For comparison, numerical methods are also used to simulate the coupled vibration; the resonance frequency and the vibrational displacement distribution are computed. Compared with one-dimensional longitudinal theory, the radial dimensions of the transducer are no longer limited because the coupled vibration is considered. Compared with numerical methods, the physical meaning of the analytic method is concise. It is illustrated that the resonance frequencies obtained from the coupled resonance frequency equations are in good agreement with those from numerical methods, and they are in better agreement with the measured results than those from one-dimensional theory. Since the radial and the coupled vibration are considered in the analysis, more resonance frequencies can be obtained. Therefore, using the coupled resonance frequency equations, the sandwich transducer with multifrequency or wide frequency bandwidth can be designed and used in ultrasonic cleaning, ultrasonic sonochemistry and other applications.

Acoustics↗