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PubMed1990

[Comparative measurement of skinfold thickness of the back of the hand with caliper and ultrasound--initial results of a prospective study].

In 110 persons the thickness of the skin on the back of the hand was measured by ultrasound (B-mode) and caliper, and the results were compared. The thickness of the skin measured by ultrasound was statistically lower than measured by caliper. This seems to be due to the better distinguishing of cutis from subcutaneous fat by ultrasound. Both methods revealed reproducible results. Caliper measurement is advantageous because of its simple handling. 10 MHz transducer is also useful for measuring the thickness of the skin.

Adult↗
PubMedDate not supplied

[Development and regression of dermal corticosteroid atrophy. 1. Change in the skinfold thickness].

We developed a method to test how quickly conventional corticosteroid ointments produce a reduction of dermal thickness and how rapidly this remits. This method is based on a measurement instrument which forms a fold from a 9 mm wide area of skin and continuously compresses it. The skin fold thickness (SFT) can be calculated from the compression plot, whereas the rate of compression (CR) can be taken as a measure of the mechanical behavior of the dermis. Clobetasol-17-propionate, betamethanone-17-valerate, diflorasone-17,21-diacetate, triamcinolane acetonide, hydrocortisone (in 10% urea), hydrocortisone butyrate and a mixture of clocortolone-21-pivalate and clocortolone-21-hexynoate were tested. The steroid products were applied under occlusive conditions for 17 d (for about 10 h during the night). Apart from hydrocortisone, the steroids led to a significant reduction in skin thickness within 6 to 10 d. After the end of the 17 d test, skin thickness returned to normal within 6 to 10 d. Non-steroidal control ointments, tested in the same way, caused a slight increase in thickness of the skin.

Administration, Topical↗