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At least 235 records · Page 13Linked to original sources
PubMed1982

Acid-base and electrolyte disturbances in dogs with gastric dilatation-volvulus.

Blood samples from 57 dogs with gastric dilatation-volvulus were analyzed for acid-base, blood gas (P02, Pco2), and electrolyte abnormalities. Although a variety of pH, blood gas, and electrolyte disturbances were recorded, metabolic acidosis and hypokalemia were common findings. Three dogs had hypochloremic-hypokalemic metabolic alkalosis. Attempts to correlate the severity of pH, blood gas, and electrolyte derangements with duration of disease, heart rate, respiratory rate, or a mathematical index based on the sum of these variables were unsuccessful. It was concluded that acid-base and fluid therapy for dogs with gastric dilatation-volvulus should be based on accurate determinations of blood pH and serum bicarbonate and electrolyte concentrations.

Acid-Base Imbalance↗
PubMed1980

Pyloric stenosis in a foal.

A two month old Thoroughbred filly was presented with signs of depression, grinding of the teeth, frothing of the mouth and abdominal pain. These signs had persisted for two weeks despite treatment with mineral oil, dioctyl sodium sulfosuccinate, meperidine and antibiotics. A variety of diagnostic tests were done, the only abnormal finding was a stress leukon. On exploratory laparotomy the stomach was dilated with fluid and gas and the pyloric canal was constricted. Pyloroplasty resulted in correction of the condition. The etiological possibilities are discussed. This is believed to be the first report of pyloric stenosis in the horse.

Animals↗
PubMed1977

Inhibitory effect of fumaric acid and dicarboxylic acids on gastric ulceration in rats.

Production of gastric ulcerations in rats by pyloric ligation was found to be inhibited by either intraperitoneal or oral administration of fumaric acid in a dose of 50 mg per kg. The antiulcer action was also exhibited by the four-carbon dicarboxylic acids, maleic acid, oxalacetic acid, succinic acid and malic acid. The studies on fumaric acid indicated that the acid's antiulcer action was based on its ability to inhibit the gastric juice secretion and to dilate the stomach muscle.

Animals↗
PubMed1997

[Celioscopic approach in surgical treatment of morbid obesity. Technique and results].

Three hundred and twenty Laparoscopic Adjustable Silicone Gastric Banding (LASGB) procedures have been performed in our institution from September, 1993 to January, 1997 for the treatment of morbid obesity. Before the first human operation a new prototype of the silicone band for laparoscopic use has been devised and a new surgical protocol developed in a preliminary animal lab programme. All the patients were morbidly obese (92-200 kg). The conversion rate to laparotomy has been very low (1.25%). Early complications have been rare. Pouch dilatation and/or stomach slippage has been the only significant late complication. The rate of this complication has been considerably improved by reducing the pouch volume and by putting more gastro-gastric sutures. The post-operative weight loss of LASGB has been comparable with our series of VBG and ASGB.

Adolescent↗
PubMed2006

Evaluation of laser Doppler flowmetry for measurement of capillary blood flow in the stomach wall of dogs during gastric dilatation-volvulus.

OBJECTIVES: To validate laser doppler flowmetry (LDF) for measurement of blood flow in the stomach wall of dogs with gastric dilatation-volvulus (GDV). ANIMALS: Six purpose-bred dogs and 24 dogs with naturally occurring GDV. STUDY DESIGN: Experimental and clinical. METHODS: Capillary blood flow in the body of the stomach and pyloric antrum was measured with LDF (tissue perfusion unit (TPU) before and after induction of portal hypertension (PH) and after PH plus gastric ischemia (GI; PH + GI) and compared with flow measured by colored microsphere technique. Capillary flow was measured by LDF in the stomach wall of dogs with GDV. RESULTS: PH and PH+GI induced a significant reduction in blood flow in the body of the stomach (P = .019). A significant positive correlation was present between percent changes in capillary blood flow measured by LDF and colored microspheres after induction of PH + GI in the body of the stomach (r = 0.94, P = .014) and in the pyloric antrum (r = 0.95, P = .049). Capillary blood flow measured in the body of the stomach of 6 dogs that required partial gastrectomy (5.00+/-3.30 TPU) was significantly lower than in dogs that did not (28.00+/-14.40 TPU, P = .013). CONCLUSIONS: LDF can detect variations in blood flow in the stomach wall of dogs. CLINICAL RELEVANCE: LDF may have application for evaluation of stomach wall viability during surgery in dogs with GDV.

Animals↗
PubMed1987

Use of intragastric balloons for weight reduction. An experimental study.

The effect of intragastric balloons as a noninvasive method for weight reduction was observed in nine castrated Yorkshire pigs. None of the animals lost weight. The appetites of the experimental animals were inhibited for only a short period of time. A significant dilatation of the stomach after balloon insertion was noted which resulted from increased food intake and obliterated the effect of the intragastric balloons. A long-standing lower blood glucose level played an important role in the increments in food intake and dilatation of the stomach. At the same time, ulceration was seen in 83.3 percent of the animals that received balloons. We conclude that intragastric balloon therapy may not be an effective approach for managing morbid obesity in human subjects.

Animals↗
PubMed1990

[Acute abdomen in anorexia nervosa. A case report].

Anorexia is a common psychiatric condition of childhood and adolescence in which, apart from the striking psychopathology, somatic complications are frequently seen. The secondary somatic findings, however, are sometimes overlooked. This case report describes a 17-year-old girl in whom, during an episode of bulimia dilatation of the stomach occurred, which presented clinically as perforation.

Abdomen, Acute↗
PubMed2006

Gastric ulceration subsequent to partial invagination of the stomach in a dog with gastric dilatation-volvulus.

CASE DESCRIPTION-An 8-year-old castrated male German Shepherd Dog was evaluated because of abdominal distension, retching, and vomiting. CLINICAL FINDINGS-Gastric dilatation-volvulus was suspected on the basis of the dog's signalment, history, clinical signs, and results of clinicopathologic analyses and abdominal radiography. Celiotomy was performed, and gastric dilatation-volvulus was confirmed along with splenomegaly. Gastric invagination was performed over an area of gastric necrosis. The dog was reevaluated 21 days later after an episode of collapse. Findings of physical examination and clinicopathologic analyses were suggestive of internal hemorrhage. Abdominal ultrasonography and subsequent celiotomy revealed severe gastric ulceration at the gastric invagination site, splenic torsion, and a focal splenic infarct. TREATMENT AND OUTCOME-Splenectomy and gastrectomy of the necrotic tissue were performed. The dog was discharged from the hospital, and the owner was instructed to administer gastroprotectants and feed the dog a bland diet. The dog was reported to be healthy 3.25 years after surgery. CLINICAL RELEVANCE-Findings suggest that complications associated with the gastric invagination procedure include severe gastric ulceration that may require subsequent surgery. Prolonged treatment with gastroprotectants following gastric invagination surgery may be necessary to avoid gastric ulceration in dogs.

Animals↗