Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “SALIVATION”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 235 records · Page 13Linked to original sources
PubMed1990

A review of the physiological significance of hypertonic body fluids on feed intake and ruminal function: salivation, motility and microbes.

Mechanisms exist in the ruminant to detect changes in osmolality and volume of plasma during feeding to maintain fluid and electrolyte homeostasis. Feed intake during a meal can be limited by the rise in osmolality of ruminal fluid, which is sensed in the wall of the rumino-reticulum. Ruminal microbes appear to be resilient to the short-term changes in ruminal fluid tonicity, but in vitro growth rates are inhibited when the tonicity of the culture medium is increased beyond physiological levels. Although mixing contractions of the rumen are not inhibited by the normal increases in tonicity of ruminal fluid, time to first rumination is increased. This aspect of motility requires further research. The tonicity of plasma increases toward the end of a large meal as a consequence primarily of absorption of VFA and Na+ from the rumen and fluid shifts into the gut. This hypertonicity is sensed centrally to inhibit parotid secretion by a reduction in the parasympathetic stimulation to the gland. Increases in animal production may result from future research directed toward developing ways of counteracting these negative effects of hypertonicity in body fluids on feed intake and ruminal function.

Animals↗
PubMed1995

Thermolytic salivation, substance P and kinins in rats.

In the heat, rats produce a large flow of saliva that they spread on their fur. We have tested whether substance P (SP) is involved in this response by using RP 67580, a NK1 tachykinin receptor antagonist, in normal and in kininogen-deficient rats. In anaesthetized rats, the sialogogic effect of SP (1 and 5 micrograms.kg-1 iv) was inhibited by RP 67580 (50 to 2500 micrograms.kg-1 iv). SP (5 micrograms.kg-1 iv) did not modify the vascular permeability to 125I-labelled albumin in submaxillary glands but increased this permeability in periglandular soft tissues and in the ears. This effect was suppressed by RP 67580 (50 to 2500 micrograms.kg-1 ip). Unanaesthetized normal male Wistar rats were exposed to ambient temperatures of 26 degrees C (thermoneutral range) or 36 degrees C for one hour. After this time period, a loss of body weight was observed. The thermolytic water loss reached 2% of body weight. This body weight loss was reduced by atropine (3 mg.kg-1 ip) or RP 67580 (50 to 2500 micrograms.kg-1 ip). The submaxillary glands were swollen and accumulated labelled albumin. This accumulation was reduced by atropine but was not affected by RP 67580. An extravasation of labelled albumin occurred in periglandular tissues. This accumulation was not modified by atropine which induced a large oedema of the soft tissues. Protein extravasation was suppressed by RP 67580 (2500 micrograms.kg-1) which did not modify or increased the volume of the oedema.(ABSTRACT TRUNCATED AT 250 WORDS)

Albumins↗
PubMedDate not supplied

Atropine sulfate--a current review of a useful agent for controlling salivation during dental procedures.

After reading this article, the reader should be able to describe techniques for the control of saliva during dental procedures; discuss the problems associated with saliva contamination of an operative field; explain the clinical benefits, dosing guidelines, and contraindications for using atropine sulfate to temporarily reduce saliva flow during dental procedures.

Atropine↗
PubMed1998

[Investigation of the clinical value of total salival flow rates].

OBJECTIVE: To investigate clinical value of total saliva flow rates. METHODS: The symptom of dry mouth was correlated with unstimulated (UWSFR) and stimulated (SWSFR) whole saliva flow rates on chewing medical paraffin in 62 patients with dry mouth complaints (30 with Sjögren's syndrome, 32 with sialosis) and 23 controls. The symptom of dry mouth was classified into 0,1,2,3,4 according to a treatment emergent symptom scale (TESS). UWSFR and SWSFR were determined after fasting in the morning. RESULTS: UWSFR was (0.070 +/- 0.089) ml/min in Sjögren's syndrome, (0.175 +/- 0.115) ml/min in sialosis, (0.330 +/- 0.188) ml/min in controls. SWSFR was (0.709 +/- 0.720) ml/min in Sjögren's syndrome, (1.561 +/- 0.867) ml/min in sialosis, (1.894 +/- 0.661) ml/min in controls. A highly significant correlation was found between TESS score and UWSFR and between TESS score and SWSFR. Only UWSFR was decreased in the patients with a TESS score of 1 or 2, while both UWSFR and SWSFR were significantly decreased in patients with TESS scores of 3,4. CONCLUSION: It is concluded that UWSFR is more sensitive in relation to dry mouth complaints than SWSFR, and that a mild dry mouth is mainly related to decreased UWSFR.

Adult↗
PubMedDate not supplied

[The relationship between the dose of caffeine and the magnitude of conditioned reflex salivation in dogs].

Statistical estimates carried out on a comprehensive experimental material of the archives in the Laboratory of physiology of nervous system types at the Pavlov Institute of Physiology, USSR Academy of Sciences, made it possible to plot average static characteristics of changes in the magnitude of positive conditioned reflexes in dogs, depending on the dose of caffeine. It appeared that conditioned reflexes decreased to some extent after a 0.01 g dose; within the range of 0.05 to 1 g doses, the magnitude of reflexes increased to the maximum; within the range of 0.1 to 0.5 g, their magnitude diminished from the maximum to the normal level, and, finally, a dose of 0.5 g or greater resulted in a drop of the magnitude of the reflexes below the normal level.

Animals↗