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On the intracardiac use of combined adrenaline, isoprenaline and noradrenaline in the resuscitation of the heart beat - A review of resuscitation, Part II.

A combination of three cardiokinetics - adrenaline, isoprenaline, and noradrenaline, ("AIN") - have been rather widely used in certain hospitals of the People's Republic of China since the beginning of the 1970s. "AIN" was initially used by intracardiac injection in an attempt to restart the asystolic heart when other therapies failed. Fifty-nine cases of restoration of the heart action with various therapies were analyzed. It was concluded that "AIN" could be recommended as first-aid drugs in the restoration of difficult cases with asystolic hearts, but not under any condition or in every case. In the patients with potential arrhythmias, such as may occur in myocardial infarction, "AIN" may induce refractory ventricular fibrillation.

Child↗

Relevance and significance of pre-CPR conditions in cardio-pulmonary-cerebral resuscitation. A graphic analysis by means of Spectramap. The Cerebral Resuscitation Study Group.

The effects of pre-arrest conditions on success rates of CPCR have been studied in 4501 circulatory arrests that have been recorded by the Belgian CPCR-Registry from 1983 to 1987. A graphical technique called Spectramap has been used for the simultaneous perception of clinical relevance and statistical significance. The success of CPCR is determined to a large extent by pre-arrest conditions. Arrests occurring inside hospitals possess a far better prognosis than those observed outside. (Overall success rate inside hospitals is 18% vs. 7% outside). Site of arrest, time to call, time to CPR, and bystander intervention appear to be relevant and significant conditions outside the hospital. Age, underlying disease and degree of disability are shown to be relevant and significant inside hospitals. The Belgian CPCR-Registry, combined with Spectramap, also allows assessment of the efficiency of emergency services and the efficacy of life supporting treatments. This article describes the graphical method of Spectramap and its application to the Belgian CPCR-Registry.

Belgium↗

Bystander cardiopulmonary resuscitation (CPR) in out-of-hospital cardiac arrest. The Cerebral Resuscitation Study Group.

Prevalence of bystander CPR and effect on outcome has been evaluated on 3053 out-of-hospital cardiac arrest (CA) events. Bystander CPR was performed in 33% of recorded cases (n = 998) by lay people in 406 cases (family members 178, other lay people 228) and by bystanding health care workers in 592 cases (nurses 86, doctors 506). Family members and lay people mainly applied CPR in younger CA victims at public places, roadside or at the working place. Sudden infant death syndrome (SIDS) and drowning are highly represented. Health care workers performed CPR mainly in older patients, at public places or at the roadside and especially in case of cardiac or respiratory origin. CA caused by trauma/exsanguination and intoxication/metabolic origin received less bystander CPR (23% resp. 22%). Cardiac arrests receiving bystander CPR are more frequently witnessed and have a shorter access time to the emergency medical service (EMS) system and shorter response time of basic life support (BLS). Advanced life support (ALS) response time is significantly longer. In witnessed arrests of cardiac origin receiving bystander CPR a significantly better late survival was observed. In non-witnessed arrests of cardiac origin early and late survival are significantly higher in patients receiving bystander CPR. In CA events where response time of ALS exceeds 8 min, the beneficial effect of bystander CPR is most significant. Furthermore no deleterious effect of bad technique or inefficient bystander CPR can be demonstrated.

Adult↗