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At least 235 records · Page 13Linked to original sources
PubMed1987

Proton relaxation time of immature brain. II. In vivo measurement of proton relaxation time (T1 and T2) in pediatric brain by MRI.

T1 and T2 of brain tissue were measured in vivo in children by means of an NMR imaging system (resistive magnet 0.15 T). The subjects were 47 children aged from 2 weeks to 15 years. The sites measured were the basal ganglia (thalamus, caudate nucleus and putamen), internal capsule, cerebral cortex and white matter. T1 and T2 in the infant cases were prolonged significantly compared with those in the older children. The prolongation in the white matter was particularly remarkable. In infants approximately 1 year of age, T1 of cerebral cortex already showed no significant changes as compared with T1 in cases aged 15 years. On the other hand, T2 was prolonged significantly up to 3 years of age.

Adolescent↗
PubMed2004

["Relaxant" awake but still relaxed].

We report on a 23-year-old female patient who underwent removal of the implants after maxillary surgery. At the end of surgery the administration of anaesthetic agents was discontinued. During the following 30 min several attempts were made to wake the patient, but she did not respond to verbal or pain stimuli. No changes in heart rate, blood pressure vegetative reactions such as sweating, lacrimation, or mydriasis were noted. Protective reflexes like coughing could not be elicited. After 30 min neuromuscular monitoring was applied and indicated residual muscle paralysis after the use of mivacurium. The patient was again sedated and transferred to the ICU, where she was mechanically ventilated for an additional 9 h. An atypical cholinesterase was determined as the underlying reason for the prolonged action of mivacurium. Retrospectively, the patient remembered the attempted wake-up period in detail. However, she reported no feelings of fear or helplessness because she had faith in the anaesthesiologist, a close friend of the patient's family for many years, who kept her calm and comfortable by talking to her during the entire period. Several months after the incident, the patient reported having neither increased fear of surgery nor any negative psychological effects on her life following this incident of awareness.

Adult↗
PubMed2006

Picosecond IR-UV pump-probe study on the vibrational relaxation of phenol-ethylene hydrogen-bonded cluster: difference of relaxation route/rate between the donor and the acceptor site excitations.

Picosecond time-resolved IR-UV pump-probe spectroscopy has been performed to study intracluster vibrational energy redistribution (ICVR) and vibrational predissociation (VP) for the OH and CH stretch vibrations of phenol-ethylene hydrogen-bonded cluster. The transient UV spectra after the picosecond IR pulse excitation of these modes were observed by 1+1 REMPI via S(1) with a picosecond UV pulse. We have focused on the difference of the energy flow routes and their rates between the donor (phenol) and the acceptor (ethylene) site. Though the transient UV spectra showed a similar broad feature for all the vibrations examined, the time profiles exhibited a remarkable site dependence, as well as substantial mode dependence. Especially, we found a large difference in the early stage of the IVR evolution and the rates, whereas the VP rates were very similar.

Journal Article↗