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Cervicofacial rejuvenation using ultrasound-assisted lipectomy.

This article discusses a technique of cervicofacial rejuvenation that involves ultrasound-assisted lipectomy. This method is indicated for those patients who might be early candidates for a rhytidectomy, and/or those with an adipose volume excess in the lower facial and cervical areas. The application of ultrasonic energy stimulates skin retraction and allows for the superficial fat to be more safely accessed than can be accomplished with conventional liposuction methods. This technique, along with a retrospective analysis of the first 26 cases treated with the technique, will be presented in this article.

Adult↗

Prominent eye: operative management in lower lid and midfacial rejuvenation and the morphologic classification system.

The purpose of this study was to evaluate a standard method for the identification of eye prominence and to review operative modifications necessary in patients with prominent eyes. A Hertel exophthalmometer was used to define a classification system according to the degree of eye prominence. A total of 43 patients undergoing lower lid or midfacial rejuvenation were included in the study. Preoperative parameters, including vector analysis, laxity, scleral show, rotational deformity, lateral canthus-to-lateral orbital rim distance, lateral-to-medial canthal distance, and exophthalmometry measurement, were documented. Intraoperatively, techniques including horizontal shortening and lateral canthoplasty placement were documented. Postoperative evaluation included scleral show, rotational deformity, and lateral-to-medial canthal distance. The proposed morphologic classification system divided patients into four groups on the basis of their degree of prominence, as measured by exophthalmometry, defined as deep-set (<14 mm), normal (15 to 17 mm), moderately prominent (18 to 19 mm), and very prominent (>20 mm). Operative techniques were different between the groups, with correction of laxity in the deep-set eyes and accentuated overcorrection of scleral show in the prominent eyes. The use of an exophthalmometer to classify patients before blepharoplasty may help reduce the risk of complications by identifying high-risk patients.

Adult↗

Meloplication of the malar fat pads by percutaneous cable-suture technique for midface rejuvenation: outcome study (392 cases, 6 years' experience).

The aging anterior midface is restored by reversing the contour undulations produced by sagging of the malar fat pad complex toward the nasolabial line. The convex irregularities include the exposed bulges of the post-septal fat, the unveiled malar bag, and the prominent nasolabial fold. The depressed irregularities are represented by the cresent-shaped hollow at the lid-cheek junction, the accentuated nasojugal groove, and the deepening nasolabial line. Repositioning of the ptotic malar fat pad, among other elements of meloplasty, represents a key procedure. In this study, the malar fat pad has been defined as a fan-shaped structure by external anatomic landmarks that correlate closely to the findings in cadaveric dissections and clinical cases, confirmed by the findings of spiral computed tomographic scanning. A simple but powerful adjustable and long-lasting percutaneous suture elevation technique was developed over the past 6 years by the senior author (G.H.S.) to reposition the fat pad in a superolateral direction. Through a dot incision within the nasolabial line, a permanent CV-3 Gore-Tex (or 4-0 clear Prolene) suspension suture, looped through a Gore-Tex anchor graft, suspends the malar fat pad in a direction perpendicular to the nasolabial line. A second suspension system is identically passed through another lower dot incision to broaden the repositioning vectors on the malar fat pad. Tension on each of the paired suture ends elevates the malar fat pad by 1 to 3 mm as measured from the nasolabial dot incisions. The sutures are fixed to the deep temporal fascia through a Gore-Tex tab, effectively stabilizing the soft-tissue repositioning. This maneuver may be performed in younger patients who present with an isolated malar fat pad ptosis without excess facial skin. The procedure may also be incorporated into open rhytidectomies to address this recalcitrant area along with superficial musculoaponeurotic system tightening. A total of 392 patients since 1995 underwent suture elevation of the malar fat pads. An outcome study indicated that the usage of two permanent sutures with Gore-Tex anchor grafts since 1998 resulted in improvement in midface rejuvenation of over 82 percent. Early and late complication rates were small and temporary. Patient acceptance was excellent, indicative of the benefits of anatomic repositioning of the malar fat pad complex.

Adipose Tissue↗

Advances in facial rejuvenation surgery.

There have been many important contributions to the literature on the subject of facial rejuvenation surgery. There has been a trend toward less invasive techniques that offer patients shorter recovery periods with levels of aesthetic satisfaction comparable to those of more invasive and complex procedures. Techniques reviewed in this article include midface suture meloplication, and purse-string suture suspension of the superficial musculoaponeurotic system to effect changes in the lower one third of the face. Another exciting area is the use of fibrin sealants and autologous platelet gels to enhance the adhesion of the tissue flaps at closure and reduce the amount of ecchymosis and edema in the recovery period. Their ability to decrease bruising, swelling, and lessen the frequency of complications has the potential of increasing patient satisfaction through a quicker return to normal activities.

Blood Platelets↗

The midface sling: a new technique to rejuvenate the midface.

In the early 1990s, the midface became the focus of facial rejuvenation, and various techniques effected elevation by plicating, or on, the midface. Recent analyses of facial aging demonstrate that selective ptosis of the midfacial tissues lateral to the nasolabial fold results in an infraorbital hollow and deepening of the nasolabial fold. Therefore, the authors propose that the midface, from the lower portion of the cheek mass, will result in superior midface positioning. Since 1996, the authors have elevated the midface in select patients by placing a sling of prosthetic (Gore-Tex) or autogenous (tendon or fascia) material through the cheek mass. The sling is secured medially to the infraorbital rim using a nonabsorbable periosteal suture or a mechanical anchor. As variable tension is applied laterally toward the superficial temporal fascia, the sling functions as a fulcrum to return the cheek mass to a more youthful anatomical position. Elevating the cheek mass in this fashion fills the infraorbital hollow and results in amelioration of deep nasolabial folds and jowling. With a mean follow-up of 18 months, 50 patients treated with the midface sling report satisfaction with the procedure. There have been no instances of nerve damage, infection, or hematoma in the midface. None of the slings have required removal and ectropion has not occurred. Because of postoperative asymmetry in one patient, additional elevation of the ipsilateral cheek mass was performed by increasing the tension on the lateral cheek portion of the midface sling. Mathematical models demonstrate the biomechanical superiority of lift through the use of multiple vectors as compared with linear pull techniques. In this fashion, the midface sling supports the cheek mass, providing rapid, simple, and secure elevation. Because of the limited subcutaneous dissection, there is a reduced risk of facial nerve damage and cutaneous vascular compromise. Unlike with other techniques, the lateral portion of the sling may be easily identified through a small incision in the temporal scalp, facilitating subsequent postoperative adjustment of the midface suspension. Furthermore, because the entire cheek mass is permanently supported with an inelastic sling, the results may last longer than those with techniques that rely on sutures to plicate or lift portions of the superficial musculoaponeurotic system.

Aging↗

A volumetric analysis of soft-tissue changes in the aging midface using high-resolution MRI: implications for facial rejuvenation.

BACKGROUND: The present study evaluated volumetric changes in the aging midface. Both young and old living subjects were studied using high-resolution magnetic resonance imaging (MRI) to investigate the distribution and volume of the muscle and subcutaneous components of the midface. METHODS: MRI with a customized radiofrequency coil was performed in 20 healthy Caucasian female volunteers equally divided between young (16 to 30 years) and old (>59 years) age groups. Sagittal oblique images were obtained at 1-mm intervals through the midface, perpendicular to the nasolabial fold. Quantitative analyses of the cheek fat pad overlying the levator labii superioris and zygomaticus major muscles were performed separately. RESULTS: For both mimetic muscles, there were no significant differences between young and old subjects in muscle length, thickness, or volume from muscle origin to nasolabial fold. In addition, there were no significant differences between age groups in fatty infiltration of the muscles. The volumes of the medial and lateral aspects of the cheek fat pad were significantly greater in old than in young subjects (p < 0.05). In young subjects the greatest distribution of fat pad volume was found in the middle third of the cheek mass. There was a significant reduction in that portion of the fat pad distributed in the upper third and a further reduction in the lower third (p < 0.01). In old subjects, because of the increased distribution of fat in the upper third of the cheek fat pad, there was no significant difference in volume between the upper and middle thirds of the cheek fat pad. The percentage increase in fat in the upper third relative to the remainder of the midface was significantly greater in old compared with young subjects (p < 0.01). In contrast, the volume of the lower third of the midface was not significantly different between young and old subjects. CONCLUSIONS: The present study indicates that ptosis alone does not account for the changes observed in the aging midface. Selective hypertrophy of the upper portion of the cheek fat pad was also observed. The mimetic muscles, on the other hand, showed no significant differences with aging. To attain maximum precision in facial rejuvenation, these data suggest that after suspension of the ptotic cheek fat pad, each patient should be evaluated for excess bulk in the upper portion of the cheek fat pad. If excess bulk is present, patients may benefit further from selective reduction directed to the upper portion of the cheek fat pad, remaining superficial to the mimetic muscles of the face.

Adipose Tissue↗

Partial rejuvenation of a colloidal glass.

We study the effect of shear on the aging dynamics of a colloidal suspension of synthetic clay particles. We find that a shear of amplitude gamma reduces the relaxation time measured just after the cessation of shear by a factor exp(-gamma/gamma(c)), with gamma(c) approximately 5%, and is independent of the duration and the frequency of the shear. This simple law for the rejuvenation effect shows that the energy involved in colloidal rearrangements is proportional to the shear amplitude gamma rather than gamma(2), leading to an Eyring-like description of the dynamics of our system.

Journal Article↗

Aging phenomena in poly(methyl methacrylate) thin films: memory and rejuvenation effects.

The aging dynamics in thin films of poly(methyl methacrylate) (PMMA) have been investigated through dielectric measurements for different types of aging processes. The dielectric constant was found to decrease with increasing aging time at an aging temperature in many cases. An increase in the dielectric constant was also observed in the long-time region (>or=11 h) near the glass transition temperature for thin films with thickness less than 26 nm . In the constant-rate mode including a temporary stop at a temperature T(a) , the memory of the aging at T(a) was found to be kept and then to be recalled during the subsequent heating process. In the negative-temperature cycling process, a strong rejuvenation effect has been observed after a temperature shift from the initial temperature T1 to the second temperature T2 (= T1 +DeltaT) when DeltaT approximately -20 K . Furthermore, a full memory effect has also been observed for the temperature shift from T2 to T1 . This suggests that the aging at T1 is totally independent of that at T2 for DeltaT approximately -20 K. As /DeltaT/ decreases, the independence of the aging between the two temperatures was found to be weakened-i.e., the effective time, which is a measure of the contribution of the aging at T1 to that at T2 , is a decreasing function of /DeltaT/ in the negative region of DeltaT . As the film thickness decreases from 514 nm to 26 nm, the /DeltaT/ dependence of the effective time was found to become much stronger. The contribution of the aging at T2 to that at T1 disappears more rapidly with increasing /DeltaT/ in thin-film geometry than in the bulk state.

Journal Article↗

Atomistic simulation of aging and rejuvenation in glasses

Slow structural relaxation ("aging") observed in many atomic, molecular, and polymeric glasses substantially alters their stress-strain relations and can produce a distinctive yield point. Using Monte Carlo simulation for a binary Lennard-Jones mixture, we have observed these phenomena and their cooling-rate dependences for the first time in an atomistic model system. We also observe that aging effects can be reversed by plastic deformation ("rejuvenation"), whereby the system is expelled from the vicinity of deep minima in its potential energy surface.

Journal Article↗

Rheological aging and rejuvenation in microgel pastes

We have studied experimentally the rheological behavior of concentrated suspensions of soft deformable microgels below the yield point. We have found history-dependent effects which are interpreted in terms of aging and rejuvenation phenomena, analogous to those existing in glassy systems. The stress amplitude controls the long-time memory and determines the slow evolution of the suspensions.

Journal Article↗

Rejuvenation and overaging in a colloidal glass under shear.

We report the modifications of the microscopic dynamics of a colloidal glass submitted to shear. We use multispeckle diffusing wave spectroscopy to monitor the evolution of the spontaneous slow relaxation processes after the samples have been submitted to various straining. We show that high shear rejuvenates the system and accelerates its dynamics, whereas moderate shear over-ages the system. We analyze these phenomena within the frame of the Bouchaud's trap model.

Journal Article↗

Generic rugged landscapes under strain and the possibility of rejuvenation in glasses.

A strain-dependent random landscape model shows that many aspects of the mechanical response of disordered materials are universal, and arise from the rugged nature of the energy landscape. Simulations with this model demonstrate that states produced by mechanical deformation will generally be distinct from the states traversed during thermal aging. This behavior is a generic consequence of a rugged energy landscape, and is independent of any specific microstructure of the material. Thus, mechanical deformation does not literally "rejuvenate" a material, although the states produced by mechanical deformation may in some ways resemble less aged systems.

Journal Article↗

Effects of rejuvenation of blood on 2,3-diphosphoglycerate and adenosine triphosphate and mechanical resistance of red blood cells.

Blood collected in ACD was supplemented with PIGP solution or PIGPA solution. The presence of adenine enhanced the mechanical resistance to trauma of erythrocytes. The levels of 2,3-diphosphoglycerate and adenosine triphosphate were restored to a normal to subnormal level. The PIGPA media seemed satisfactory for rejuvenation of stored blood for freezing purposes.

Adenine↗

Fat injections for facial rejuvenation: 17 years experience in 1720 patients.

BACKGROUND: Autologous adipose tissue has been proved to be an excellent filling material. Fat injections can correct cosmetic defects that are caused by loss of subcutaneous tissue, such as atrophy of the face due to significant weight loss, wrinkles and facial involution due to ageing. OBJECTIVE: To evaluate the safety and long-term results of facial rejuvenation by autologous fat injections using the fine-needle technique to inject fat and frozen fat for repeating the implantation procedure. METHOD: Patients were evaluated clinically and photographically. Extraction, processing and implantation of fat were performed using an anaerobic technique. The fat was harvested by tumescent liposuction, using syringes and small diameter blunt-tip cannulas (2-3 mm). After washing the collected fat in normal saline it was centrifuged, transferred to small syringes (1-2.5 mL diameter) and then injected subcutaneously using fine needles of 21-23 G. Hypercorrection was avoided, so one or two repetitions of the fat injections were usually necessary, at intervals of at least 1 month, in order to achieve the desired cosmetic result. Using frozen fat simplified repeat fat implantation. RESULTS: The clinical long-term follow-up of 1720 patients up to 17 years is presented. Absorption of the injected fat was estimated at 40-60%. The absorption rate varied a lot in each case. Long-term follow-up proved that final correction after two or more repetitions of frozen fat injections, persisted for many years, the longest proved to be more than 12 years. CONCLUSIONS: The advantages of the fine-needle technique for fat grafting were very important: more accurate and refined work, less painful injections, no scars at needle puncture points, early treatment of small defects, and the facility to treat multiple sites, even the entire face, in one session. There were no major complications. Oedema and sometimes echymoses at the donor site for 6-10 days and slight bruising at the injected areas for 3-5 days are the disadvantages of the procedure.

Journal Article↗

Botulinum toxin - an update on its use in facial rejuvenation.

The role of botulinum toxin in facial rejuvenation has been greatly expanded in the last several years. In this article, we first review the traditional approach to botulinum toxin therapy in the forehead and glabella. For the advanced reader, we then discuss both the literature and our personal approaches to treatments of the periocular region, mid face, lower face, and neck. Throughout the discussion, attempts are made to include a description of relevant anatomy, the physiologic result of specific muscle activity and denervation, and perhaps most importantly, precise directions for patient treatment.

Journal Article↗

Nonablative radiofrequency for facial and neck rejuvenation. A faster, safer, and less painful procedure based on concentrating the heat in key areas: the ThermaLift concept.

Nonablative radiofrequency was the first method of noninvasive tissue contraction. It is a safe and effective method, although the results are modest when compared with plastic surgery. Patients like the fact that it requires no down time, it is performed with topical anesthesia, and it can be combined with numerous other modalities of skin rejuvenation. Technique and results are discussed.

Facial Expression↗

Dynamics of concentrated colloidal suspensions during drying--aging, rejuvenation and overaging.

We report on the slow dynamics of concentrated colloidal suspensions during drying and rewetting under conditions of reversible concentration changes without coalescence or aggregation. We used multispeckle diffusing-wave spectroscopy to monitor the slow dynamics of particles. We found that the alpha relaxation of the suspensions exhibits successively slowing-down, acceleration and a stationary regime during drying at constant rates. Under rewetting conditions, we observed slowing-down and a stationary regime. The characteristic time of the stationary regime is inversely proportional to the rate of concentration change and identical for both drying and rewetting. We explain these regimes as aging (overaging), rejuvenation and plastic flow of the suspensions induced by a deviatoric stress (a combination of compressive and elongational stresses) which is induced by the uniaxial compressive strain generated by evaporation.

Journal Article↗