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At least 235 records · Page 13Linked to original sources
PubMed1988

Spastic paraparesis and HTLV-I infection in Peru.

Three of 6 patients with spastic paraparesis in Lima, Peru, were found to have antibodies to human T-lymphotropic virus type I (HTLV-I). Blood and cerebrospinal fluid antibodies were confirmed by Western blot analysis. Multilobulated lymphocytes in blood and cerebrospinal fluid of the index case stained with monoclonal antibodies for T-helper cells and for T10, an activation marker. Blood mononuclear cells from patients with HTLV-I-associated myelopathy showed spontaneous proliferation in culture, evidence of interleukin-2 receptors, and decreased natural killer cell activity.

Adult↗
PubMedDate not supplied

Popular participation and the state: democratizing the health sector in rural Peru.

Popular participation has been an important component of most primary health care strategies since the Alma Ata Declaration, 1978. This article examines the use of state-sponsored participation in the health sector in Peru and some of the experiences that have accompanied its implementation. Taking the Local Health Administration Committees (CLAS) from the second Fujimori government (1995-2000) as an example, it is shown that for self-motivated rural communities to work in harmony with the state, there must be willingness to adapt to the varying levels of intra-community differences, social integration and social support.

Community Participation↗
PubMed1994

Chronic liver disease in Peru: role of viral hepatitis.

The prevalence of antibodies to hepatitis C virus (anti-HCV) was determined in 105 patients with biopsy-proven chronic liver disease and 128 comparison patients without any evidence of liver pathology living in Lima, Peru. Using a second-generation EIA screening and supplemental immunoblot assay, anti-HCV was detected in four of 13 patients with chronic hepatitis, in 11% of 85 patients with cirrhosis, and in none of seven patients with hepatocellular carcinoma. Only two (1.6%) comparison patients without liver disease had anti-HCV. Hepatitis B surface antigen (HBsAg) was found in 23% of patients with chronic hepatitis, 12% of patients with cirrhosis, and three of seven patients with hepatocellular carcinoma. There was no evidence of chronic viral hepatitis or alcohol abuse (reported by one-third of subjects) in 48% of chronic liver disease patients. These preliminary data suggest that among this South American population neither hepatitis B nor hepatitis C infection is the predominate cause of chronic liver disease and that other infectious or environmental factors may be important.

Adult↗
PubMed2001

Allpahuayo virus: a newly recognized arenavirus (arenaviridae) from arboreal rice rats (oecomys bicolor and oecomys paricola) in northeastern peru.

Allpahuayo virus was initially isolated from arboreal rice rats (Oecomys bicolor and Oecomys paricola) collected during 1997 at the Allpahuayo Biological Station in northeastern Peru. Serological and genetic studies identified the virus as a new member of the Tacaribe complex of the genus Arenavirus. The small (S) segment of the Allpahuayo virus prototype strain CLHP-2098 (Accession No. AY012686) was sequenced, as well as that of sympatric isolate CLHP-2472 (Accession No. AY012687), from the same rodent species. The S segment was 3382 bases in length and phylogenetic analysis indicated that Allpahuayo is a sister virus to Pichinde in clade A. Two ambisense, nonoverlapping reading frames were identified, which result in two predicted gene products, a glycoprotein precursor (GPC) and a nucleocapsid protein (NP). A predicted stable single hairpin secondary structure was identified in the intergenic region between GPC and NP. Details of the genetic organization of Allpahuayo virus are discussed.

Amino Acid Sequence↗
PubMed1999

Herb Hultgren in Peru: what causes high altitude pulmonary edema?

Herbert Hultgren, a cardiologist who kept a careful diary all his career, arrived in Peru at the beginning of 1959 to study the occurrence of pulmonary hypertension in children at high altitude with patent ductus arteriosus. There, he was told about a strange condition, high altitude pulmonary edema (HAPE), and found that to Peruvian physicians looking after mine employees and their families, its occurrence was almost routine. With his Peruvian colleagues, Herb immediately began a systematic study of the condition, including catheter studies. Though the absence of left ventricular enlargement suggested a non-cardiac form of pulmonary edema, and though this is what he suggested in his first publication, in two subsequent papers, one written with Charles Houston, who contributed cases occurring in mountaineers, Herb wrote that the most probable cause was left ventricular failure. What is extraordinary is that before he finally submitted the two papers, he had certain knowledge that in one case of HAPE at least, left atrial pressure had been shown to be normal. Herb's contributions, then and later, to the elucidation of HAPE were enormous.

Altitude Sickness↗
PubMed1990

Screening and surgical intervention results from cataract-free-zone projects in Campinas, Brazil and Chimbote, Peru.

Two cataract-free-zone projects, one in Brazil and the other in Peru, were designed to provide surgery to all those who need and want it within a defined geographic area. In-home visual acuity screening was accepted by three-fourths of the enumerated population aged 50 years or more. Those with reduced bilateral visual acuity were referred to a community health post for ophthalmic examination. Among those diagnosed as bilaterally blind (less than or equal to 20/200), comprising 5% of the screened population, two-thirds were thought to be blind from cataract. Because of other ocular pathology and general health conditions, surgery was not indicated for 30-50%. Two-thirds of those recommended for out-patient surgery accepted. Motivational efforts to convince the refusers were uniformly unsuccessful. The average age of those accepting and those refusing surgery was in the mid-seventies. Those already aphakic were 7-8 years younger. Post-operative acuity was greater than or equal to 20/50 for only one-half of those operated. A significant number of cases had previously undetected macular degeneration and other causes of decreased vision. These projects have given increased attention to cataract blindness and the need for further operational research to develop effective methods for its control using outpatient surgery.

Aged↗
PubMed1978

[An osseus tumor in the skull of a precolumbian indian from Peru (author's transl)].

A walnut-sized, stalked, osseus tumor in the region of the protuberantia occipitalis externa of the skull of a precolumbian indian from Peru is described. Radiological and histological examinations grouped this neoplasm with the fibro-osseus tumors. Cytologically, it is one of the rarely seen nearly compact forms of the large, mostly spongy osteomas of the skull roof.

Diagnosis, Differential↗
PubMed1975

[Microflora of the atmosphere in the city of Trujillo (Peru). III. Genera isolated during the year 1971].

There were 1762 fungi isolated from the atmosphere of Trujillo city (Peru) during the year 1971. These isolants belonged to 23 genera of fungi. The most frequently isolated were: Cladosporium, Penicillium, Fusarium, Stemphylium, Alternaria, Helminthosporium, Aspergillus and Tilachlidium. Nine genera are reported for first time from the air of the city (Tilachlidium, Cephalosporium, Mucor, Aureobasidium, Hormiscium, Trichoderma, Stachybotrys, Paecilomyces and Fisidium). Six genera may be alergenic for asthmatic patients of Trujillo city.

Air Microbiology↗
PubMed1991

Childhood cross-gender behavior of homosexual females in Brazil, Peru, the Philippines, and the United States.

Heterosexual and homosexual females were interviewed with regard to childhood cross-gender behavior in Brazil, Peru, the Philippines, and the United States. Nine items were used to examine childhood behavior differences between heterosexual and homosexual females. Six of these items (playing with boys' toys, playing with girls' toys, dressing up in men's clothes, dressing up in women's clothes, paying attention to women's fashions, and being considered a tomboy) revealed statistically significant differences between the heterosexual and homosexual females. These differences demonstrated significant cross-cultural consistency, despite cultural variations among the societies examined. Rejection of certain gender-typical activities and interests, as well as involvement in cross-gendered activities and interests, seem to be consistent precursors of adult sexual orientation regardless of the cultural context in which these behaviors emerge.

Brazil↗
PubMed1979

[Integration of health development cooperation into the cultural and socioeconomic context of the operational area: work of the Putina medical team in Peru].

Contrasting with what happened with the indio traditional medicine and with the Western medical knowledge the Spaniards imported, industrialized nations' medicine, through its growing ability to fight infectious diseases, has sharpened in Peru in the 20th century the social disparity between the well-to-do upper classes and the poor masses. In order to alleviate this situation, efforts have been undertaken since the 1940's in the Department of Puno, the poorest of the country, in order to bring to the rural population the benefits of modern medicine. Since 1971, a team of Swiss physicians, integrated into the Peruvian Ministry of Health, works in the Putina area in several State health centers. There are presently five doctors for a 130,000 inhabitants population, collaborating in the setting up of basic health services. The most important pillars of the programme, which should be able to function without physicians, if need be, are voluntary health auxiliaries, chosen by their own community (1 per 500 people). State employed auxiliary nurses (1 per 5000 people), and Peruvian State Registered nurses, entrusted with training and supervisory tasks. The progress of the programme, in terms of the growing independence of the basic health system, is described, as are potentialities and limits in bringing it closer to the indigenous traditional medicine. Through the example of the supply of basic drugs, it is pointed out how setbacks suffered in the last two years, are illustrative of the country political crisis and of its growing dependency on industrialized nations.

Developing Countries↗
PubMed1991

Leptospira interrogans serovar canicola: a causal agent of sow abortions in Arequipa, Peru.

An outbreak of abortions, stillbirths, mummified piglets and neonatal deaths in a pig herd in Arequipa, Peru is described. A total of 31 of 240 sows aborted between May and September 1988. When sera were examined 12 of 14 had very high titres of antibody to canicola PC125 and canicola Hond Utrecht, but there were also high titres of antibody to other leptospiral serovars. A detailed investigation was made and serovar canicola PC125 was isolated from the urine of four sows which had aborted and the kidney of one slaughter pig. Antibodies to various serovars of Leptospira were demonstrated in 11 of 17 sows which had aborted, two of six sows which had normal litters, nine of 18 boars, four of 39 slaughter pigs and four of 14 workers on the farm. The outbreak was brought under control by treatment and vaccination coupled with a thorough cleaning of the farm and control of the wild animal population. It is suggested that the infection was brought onto the farm by wild animals and that the disease is more common in Arequipa than was previously supposed.

Abortion, Veterinary↗
PubMed2005

Socio-demographic, behavioral and functional characteristics of groups of community and institutionalized elderly Quechua Indians of Peru, and their association with nutritional status.

Socio-demographic, behavioral, functional and anthropometric data for groups of elderly Quechua Indians of Peru were used to investigate the effects of gender and lifestyle patterns on nutritional status. Two community-dwelling samples were selected for study, representative of divergent lifestyles in terms of their combination of socio-economic, demographic and cultural contexts, plus an ad-hoc sample of institutionalized individuals with controlled food intake and reduced physical activity. Results suggest that differences in socio-demographic, behavioral and functional characteristics exist between the sexes and across settings (low- vs. highland) and lifestyles (institutionalized vs. community-dwelling; semi-urban vs. rural). These factors are likely to be related to diverging dietary and physical activity patterns, and have considerable effects on the nutritional status of the respondents.

Aged↗
PubMed1995

Putative Leishmania hybrids in the Eastern Andean valley of Huanuco, Peru.

During an outbreak of tegumentary leishmaniasis that developed in the 1990s in the Eastern Andean valley of Huanuco, Peru, the coexistence of Andean (uta) and sylvatic leishmaniases was suspected for ecological and geographical reasons, and sympatric sampling was carried out. Seven human isolates of Leishmania were characterized by multilocus enzyme electrophoresis, random amplification of polymorphic DNA and molecular karyotyping. The three methods identified 3 isolates as L. braziliensis, and 4 isolates as putative hybrids with characters of L. braziliensis and L. peruviana. Data from Huanuco are compared to previous results from other areas endemic for uta. Biological and epidemiological implications are discussed.

Animals↗
PubMedDate not supplied

The fall and rise of Andean cutaneous leishmaniasis: transient impact of the DDT campaign in Peru.

A retrospective analysis was carried out on census data collected from house-to-house surveys during 1991-1992 in 4 areas endemic for Andean cutaneous leishmaniasis (uta) in the Department of Lima, Peru. Major changes in mean annual incidence in susceptible persons have taken place in these sites during the last 60 years. In particular, there is strong support for the hypothesis that, from the 1950s to the 1970s, the transmission rate was temporarily suppressed, largely as a by-product of the DDT house spraying campaign against malaria. These results are consistent with (i) anecdotal evidence, contemporary with the spraying campaign, and (ii) the official Ministry of Health records for the annual number of uta cases in the Departments of Lima and Ancash.

Adolescent↗
PubMed1983

Beliefs regarding the etiology and treatment of infantile diarrhea in Lima, Peru.

Three groups of women in Lima, Peru, were interviewed regarding their beliefs about the etiology and treatment of infantile diarrhea. The first group consisted of 91 mothers of children under the age of 2. These were interviewed at two locations: the pediatric emergency service of a teaching hospital serving northern Lima and a health center located in one of the rapidly growing shantytowns surrounding Lima. The second group consisted of 25 women interviewed in their homes in several shantytowns. Answers given by mothers in both groups were similar. All women were of low socioeconomic status. The third group consisted of 23 adolescent girls and young women interviewed briefly at two schools in Lima. Results of the interviews confirm that diarrhea is not seen as an infectious disease. Instead, it is placed within the framework of the hot--cold dichotomy prevalent in Latin America; diarrhea is believed to be caused by invasion of the body by cold or by ingestion of foods designated as being 'cold'. Suspension of milk feeding is also thought to be an essential part of treatment, a finding of importance in view of the decline in breastfeeding.

Adolescent↗
PubMed1987

The process of acculturation: theoretical perspectives and an empirical investigation in Peru.

World-wide migratory patterns have led to an increasing interest in acculturation processes and their psychosocial and psychiatric sequelae. This paper reviews alternative theoretical approaches to the study of acculturation and identifies gaps in the current knowledge base. We then present empirical research on acculturation processes experienced by both Indian rural to urban migrants and White-Mestizo non-migrants in Lima, Peru. The study examined overall acculturation and five sub-dimensions: language use, customs, sociability, perceived discrimination and ethnic identity. The data show that second generation migrants are more highly acculturated across sub-areas and perceive less ethnic discrimination than first generation migrants. The first generation varied in acculturative level across sub-dimensions as a function of their age at the time of migration. Contrasts between the migrant and dominant group depicted a two-way process of culture change, but a process characterized by an inequality in the content exchanged in each direction. Socio-demographic correlates of acculturation were also found. These results are discussed in terms of the potential psychological consequences of alternative acculturative adaptations within the Peruvian social-structural context.

Acculturation↗
PubMed1988

Mortality in children among the Aymara Indians of southern Peru.

During the fieldwork on illness in children in an Aymara peasant community in Southern Peru, data was collected on child mortality. In 35 families surveyed in the village, the total child mortality rate was estimated diachronically at 380 per 1,000 live births. The majority of the child death in these families occurred in the first days after birth. These deaths were also counted as perinatal deaths, and thus the perinatal mortality rate was found to be high as well at 252 per 1,000 total births (99% confidence interval: 181-330 per 1,000). Congenital malformations incompatible with life, neonatal tetanus, and other neonatal disorders did not have an especially high frequency in the village. These disorders seem to explain only a part of the early neonatal deaths responsible for the high mortality rates in children. As perinatal deaths were concentrated in 13 of the 35 families in the survey (especially in those families with many total births and at least two living children), the possibility of infanticide was put forward to explain the high death rates in children in the first days of life. This hypothesis was supported by practices in the village concerning the baptism of dead children by which the cause of death was left unsanctioned. Infanticide could be important to curb recent and future population growth and the resulting pressure on the land.

Adolescent↗