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PubMed1977

[Studies on pyrazolo [3,4-d] pyrimidine derivatives. VIII. On syntheses and anti-tumor activity of 4-amino-1-(o-, m- or p-nitrophenyl) -1H-pyrazolo[3,4-d] pyrimidines and their derivatives (author's transl)].

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Animals↗

PubMed1978

[Studies on pyrazolo[3,4-d]pyrimidine derivatives. IX. On 4-(p-tolylsulfonyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (author's transl)].

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Chemical Phenomena↗

PubMed1978

[Studies on pyrazolo[3,4-d]pyrimidine derivatives. X. On the reaction of 1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 5-oxide with methanesulfonyl chloride and potassium cyanide (author's transl)].

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Chemical Phenomena↗

PubMed1978

[Studies on pyrazolo(3,4-d)pyrimidine derivatives. XI. On 1-phenyl-1H-pyrazolo(3,4-d)pyrimidine-4-carbonitrile (author's transl)].

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Chemical Phenomena↗

PubMed1978

[Studies on pyrazolo[3,4-d]pyrimidine derivatives. XII. On 1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-carboxylic acid (author's transl)].

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Chemical Phenomena↗

PubMed1979

[Triazolo[4,5-d]pyrimidines. I. On the reaction of 7-chloro-3-methyl-3H-1,2,3-triazolo[4,5-d]pyrimidine with nucleophile (author's transl)].

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Amines↗

PubMed1959

[The complex chemical behavior of pyrimidine derivatives. I. The complex chemical behavior of simple pyrimidine derivatives toward copper ions].

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Copper↗

PubMed1959

[The complex chemical behavior of pyrimidine derivatives. II. The complex chemical properties of 4,5-diamino-6-substituted pyrimidines toward copper, cobalt and nickel].

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Cobalt↗

PubMed1969

Fluorinated pyrimidines. XXXI. Mechanisms of inhibition of vaccinia virus replication in HeLa cells by pyrimidine nucleosides.

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Culture Media↗

PubMed1976

[The effect of various purine and pyrimidine derivatives on human pyrimidine synthesis].

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Adenosine Monophosphate↗

PubMed2003

Synthesis of some new pyrimidine and fused pyrimidine derivatives (Part 2).

6-Oxo-4(2-thienyl)-2-thioxo-1,3-dihydropyrimidine-5-carbonitrile (1) was synthesized and reacted with alkyl halides to give the S-alkyl compounds (2a,b), which reacted with phosphorous oxychloride to yield (3a,b). Reaction of 3a,b with phenyl-hydrazine, hydrazine hydrate, ammonia, acid hydrazides and thiourea leads to formation of the compounds (4a,b), the dihydrazino compound derivative (5), the amino compounds (7a,b), triazolopyrimidine derivatives (9a-d), and the mercapto compounds (10a,b), respectively. Treatment of (10a) with chloroacetone gave (11a), which condensed with benzaldehyde giving the tricyclic compound (12). Also (10b) reacted with ethyl chloroacetate followed by hydrolysis and cyclization yielded (14). Heating of (5) gave (6), which reacted with sodium nitrite and/or carbondisulphide and give (15) and (16), respectively.

Cyclization↗

PubMed1957

Studies on the biosynthesis of bacterial and viral pyrimidines. IV. Utilization of pyrimidine bases and nucleosides by bacterial mutants.

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Escherichia coli↗

PubMed1957

Pyrimidine research; the action of amines and hydrazine on ethyl 2-methyl-mercapto-4-methyl-pyrimidine-5-carboxylate.

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Amines↗

PubMed1958

[Action of homologous derivatives of the pyrimidine bases of nucleic acids on cell division in plants; influence of substituants in the pyrimidine nucleus on the toxicity of the molecule].

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Cell Division↗

PubMed1961

Effects of 4-aminopyrazolo (3,4-d)pyrimidine and 1-methyl-4-aminopyrazolo(3,4-d)pyrimidine on nucleic acid purine metabolism in ascites tumors.

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Adenine↗

PubMed1960

OETTGEN HF, REPPERT JA, COLEY V: Studies on the synergism of fluorinated pyrimidines and certain pyrimidine and purine derivatives against transplanted mouse leukemia.

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Animals↗

PubMed1959

Pyrimidine studies. II. Effect of 5-bromodeoxyuridine and related nucleosides on incorporation of precursors into nucleic acid pyrimidines.

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Bromodeoxyuridine↗

PubMed1961

Radiation chemistry of nucleic acids and their derivatives. I. Some pyrimidines, dihydropyrimidines and hydrated pyrimidines.

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Nucleic Acids↗