Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “PRIAPISM”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 235 records · Page 13Linked to original sources
PubMed2003

[Pediatric priapism associated with pulmonary infection].

Priapism is a rare urologic emergency in pediatric population. It is usually a consequence of sickle cell disease. Leukemia is another important cause of priapism in children. We present a case of priapism associated with an acute pulmonary infection. To our knowledge, this is the second case describing this association. In the other reported case, pulmonary infection was related to Mycoplasma Pneumoniae. The hypothesis is that infection with Mycoplasma Pneumoniae can produce a hypercoagulable state, especially in selected areas of the circulation.

Child↗
PubMed1993

Gonadotropin-releasing hormone analogues in the treatment of sickle cell anemia-associated priapism.

Priapism secondary to sickle cell anemia has been treated with a variety of therapeutic regimens. Recurrent sickle cell priapism is common and in many cases results when detumescence has not been achieved reliably. We report on a patient with sickle cell disease and recurrent priapism who was treated successfully for more than a year with monthly gonadotropin-releasing hormone analogue therapy after failure of standard medical management.

Adolescent↗
PubMed1993

Association of sickle cell disease, priapism, exchange transfusion and neurological events: ASPEN syndrome.

Priapism and acute neurological events are believed to be unrelated complications of sickle cell hemoglobinopathy. We describe a syndrome based on our experience and a review of the literature of significant neurological events after partial exchange transfusion to treat priapism in sicklemic patients. Severe headache is often the initiating symptom of this complex. The ensuing neurological events range from seizure activity to obtundation requiring ventilatory support. The proposed pathophysiology of these neurological events is related to cerebral ischemia after an acute increase in per cent total hemoglobin, concomitant decrease in per cent hemoglobin S and subsequent release of vasoactive substances during penile detumescence. We have termed this constellation of events the ASPEN syndrome, an eponym for association of sickle cell disease, priapism, exchange transfusion and neurological events. Early recognition and aggressive medical management resulted in complete reversal of neurological sequela.

Child↗
PubMed1992

Clozapine-induced priapism.

Priapism may be a side effect of certain medications. We present a case of priapism associated with the nonphenothiazine antipsychotic drug clozapine. The possible mechanism for the drug-induced priapism is discussed.

Adult↗
PubMed1989

Priapism: an avoidable complication of pharmacologically induced erection.

Priapism is an alarming complication during treatment of erectile dysfunction with vasoactive drugs, particularly papaverine alone or in combination with phentolamine mesylate. An investigational protocol was designed to identify patients who are more susceptible to priapism after intracavernous injection of papaverine alone or with phentolamine. The protocol was applied in 331 men with impotence of various etiology. The association of a positive response to visual sexual stimulation and penile brachial index of more than 0.8 represented a higher risk for post-injection priapism. We were able to reduce the incidence of this compliance to 1% in the last 101 patients.

Humans↗
PubMed1990

Impotence following childhood priapism.

Priapism in childhood, although an uncommon event, generally is believed to be associated rarely with future impotence in adulthood. These beliefs may be a reflection of under-reporting or a lack of long-term followup. We present a case of a 23-year-old impotent man who had a history of priapism as an 8-year-old child. Even though a review of the literature reveals that impotence following childhood priapism is an infrequently reported phenomenon we believe its incidence to be significant and since it can occur aggressive treatment is essential.

Adult↗
PubMed1990

Priapism: simple method to prevent retumescence following initial decompression.

With recent escalation in the use of vasoactive intracorporeal injections to produce erection, the precise treatment of priapism has again achieved much attention. In particular, high inflow priapism must be managed rapidly and definitively to reestablish equilibrium with venous outflow. However, once penile decompression has been achieved tumescence of the penis can recur if appropriate measures are not taken. This may result in additional penile manipulation and operations leading to an increased risk of impotence. A simple method is presented to prevent recurrent tumescence after initial treatment of priapism, irrespective of the etiology.

Adult↗
PubMed1988

Experience with 105 patients with priapism: update review of all aspects.

A 26-year experience with all aspects of priapism is reviewed in 105 children and adults. The etiology of the priapism was idiopathic or drug-induced, or owing to sickle cell disease, trauma, neoplasia, leukemia, papaverine-phentolamine injections and total parenteral alimentation. The pathophysiology of prolonged erection is discussed. Treatment is reviewed in respect to initial studies before the type of shunting procedure required is selected. Various shunt techniques are presented with outcome. Complications and their possible causes are discussed, and the importance of medicolegal risk is emphasized. Impotence is a common sequela of priapism.

Adolescent↗
PubMed1988

Priapism associated with trazodone therapy.

Priapism associated with medication use is well known as one of the most difficult forms of priapism to treat. We report 2 cases of priapism and prolonged erection associated with trazodone therapy. The literature is reviewed and potential treatment options are discussed.

Adult↗
PubMed1985

Priapism associated with the use of intravenous fat emulsion: case reports and postulated pathogenesis.

During the 8 years since inception of a home total parenteral nutrition program in 35 male patients 2 suffered priapism related temporally to the weekly intravenous infusion of 20 per cent fat emulsion. Fat emulsions have been shown to cause hypercoagulability, capillary thrombosis and fat embolus in in vivo and in vitro experiments. Autopsies of patients treated with intravenous fat emulsion have revealed capillary engorgement and fat embolus with associated organ infarction. We postulate that fat emulsions may cause priapism in these patients. Because of the more frequent occurrence of priapism in this small subset of patients we now recommend that 1) patients be informed of this potential complication before hyperalimentation is begun, 2) the less concentrated 10 per cent emulsion should be used twice weekly, rather than the 20 per cent emulsion weekly, and should be infused during at least 4 hours, and 3) the fat emulsion should be added to other components of the intravenous regimen, when possible, to dilute the fat and prolong its administration time.

Adult↗
PubMed1983

Automated erythrocytopheresis for relief of priapism in sickle cell hemoglobinopathies.

Priapism, a complication of male patients with sickle hemoglobinopathies, has been managed by a variety of surgical and nonsurgical forms of therapy that often are unsuccessful. The application of automated erythrocytopheresis (red blood cell exchange) by continuous-flow and semicontinuous-flow procedures appears to offer distinct advantages in the treatment of complications resulting from sickle hemoglobinopathies. The successful application of erythrocytopheresis for the relief of priapism in a patient with hemoglobin SC disease is presented and probably represents the first case reported on the use of automated red blood cell exchange procedures in the treatment of this condition. Data and results of automated erythrocytopheresis in 4 additional patients are presented. The advantages and disadvantages of erythrocytopheresis in the treatment of priapism (and other complications of sickle hemoglobinopathies) are discussed and the method is compared to other modes of therapy.

Adult↗
PubMed1981

Surgical management of priapism in children with sickle cell anemia.

Priapism has been reported to occur in 2 to 5 per cent of patients with sickle cell disease. Recently, creation of a percutaneous fistula between the glans penis and the corpora cavernosa has been applied widely in the management of patients with priapism, except in those cases of sickle cell anemia. Reported failures of such shunting procedures in the sickle cell patient has perhaps unduly denied surgical benefits to that population. We have managed successfully 5 such children with sickle cell anemia and priapism without complications by creation of a fistula between the glans penis and the corpora cavernosa. Our treatment plan is presented, which includes early shunting should initial nonoperative treatment fail.

Anemia, Sickle Cell↗
PubMed1981

Evaluation and treatment of priapism.

We herein review the last 29 patients with priapism treated at our hospitals with respect to the physiology and pathophysiology of erection and priapism, respectively, and present a rational approach to the management of priapism. Emphasis is given to the corpus cavernosum to corpus spongiosum shunt with a vascular anastomosis technique.

Adolescent↗
PubMed1978

Idiopathic priapism in the newborn.

Priapism in children usually results directly or indirectly from an underlying cause. Secondary priapism is extremely rare in neonates and idiopathic priapism has not been described previously.

Humans↗
PubMed1976

Association of priapism in phenothiazine therapy.

We present 4 patients seen in the last 5 years who had taken thioridazine (Mellaril) prior to development of priapism. One of the 4 patients suffered penile trauma while taking the phenothiazine drug and this is another possible etiologic factor in that case. No underlying urologic or hematologic disorders were present. All patients were treated by corporeal aspiration and corpus cavernosum-corpus spongiosum shunts. The mechanism of phenothiazine=induced priapism is hypothesized as being related to its peripheral adrenergic blockade, perhaps directly blocking the sympathetic impulse for detumescence, although a central nervous system effect must be considered as well. Lastly there exists the possibility of coincidence since phenothiazine treatment is becoming more common and was unrelated to the condition in an additional 6 patients with priapism seen during the same period.

Adult↗
PubMed2001

Arterial priapism and cycling: a new worrisome reality?

Arterial priapism is a rare condition caused by the traumatic formation of an arteriolacunar fistula. We report 2 cases of arterial priapism after cycling injuries. Both patients sustained a violent perineal trauma against the top tube on the bicycle. In both cases, penile detumescence was obtained by superselective arteriographic embolization of the fistula with gelatin sponge or microcoil. The fistula was monolateral in the first case and bilateral in the second. Cycling should be considered a possible risk factor for arterial priapism as it is for urethritis, prostatitis, hematuria, testicular torsion, scrotal and penile numbness, and erectile dysfunction.

Adult↗
PubMed2001

Priapism from quetiapine overdose: first report and proposal of mechanism.

We report a case of priapism occurring after an overdose of the newly approved atypical antipsychotic quetiapine. A review of its previously published receptor-binding studies suggests that alpha-adrenergic blockade may be the responsible mechanism. To our knowledge, this is the first report of priapism associated with quetiapine, and we recommend the inclusion of priapism in its list of potential adverse effects in cases of overdose.

Adrenergic alpha-Antagonists↗