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At least 235 records · Page 13Linked to original sources
PubMedDate not supplied

[Possibility of nerve lesions related to peripheral nerve blocks. A study of the human sciatic nerve using different needles].

UNLABELLED: When a needle tip comes too close to a nerve axon, the mechanical effect over the nerve membrane produces paresthesia. We examined the hypothetical mechanical damage of short bevel and long bevel needles over sciatic nerve bundles under scanning electron microscopy. METHODS: We obtained samples of sciatic nerve from three patients of 68, 74 and 76 years old. These samples were fixed, dehydrated and coated with gold microfilm for their observation under scanning electron microscopy. Ten short bevel needles and ten long bevel needles were studied under the same microscopic technique. We interpolated microscopic images from sciatic nerve samples and different needle bevels at various angles to study the mechanical damage of these needles to nerve axons. RESULTS: Sciatic nerve bundles were found 0.1 to 0.2 mm deep in the samples; information was given about the bevel length and angle of needles. The damage is perceptible under scanning electron microscopy, when the needle bevel is introduced 0.3-0.4 mm deep into the nerve bundle; here, the needle tip cuts through the perineurum, piercing the nerve bundle. At a depth of 1 mm, the lesion caused by short bevel needles is greater than that caused by long bevel needles. The type of epineural lesions caused by short bevel needles is also different from the ones caused by long bevel needles. CONCLUSIONS: Lesions that affect superficially the epineurum can cause paresthesia by compression of nerve fascicles without damaging the axons. If the perineurm is damaged, the lession will also affect the blood-nerve barrier, leading probably to posterior sequels.

Aged↗
PubMed1965

TWENTY-FIVE YEARS OF TRANSLATING SERVICE AT NIH.

The growth of the Translating Unit of the National Institutes of Health Library, founded in 1938, was slow until 1950, when seventeen translators and clerical assistants comprised its staff. Today eleven staff members translate, type, and distribute translations from eighteen European languages. Contract service is arranged for those languages for which the Unit has little or no competency. Three recent innovations have improved the translating service: (1) production standards, (2) fee for service, and (3) microfilmed translations. A monthly bulletin, Recent Translations, a Selected List, includes those articles translated by the Translating Unit of the NIH Library. An author index to all translations cited in the Selected List is now available upon request.

Computer Systems↗
PubMed2002

Influence of hypergravity on hypothalamic vasopressin and oxytocin neurons in rats.

This study was aimed to evaluate the reaction of the vasopressin (VP) and oxytocin (OT) neurons of the supraoptic nucleus (SON) in rats to single or repeated hypergravity (HG). Special attention was paid to the tyrosine hydroxylase (TH) expression in VP neurons as a marker of the neuron activation. Rats were revolved in a centrifuge with overloading 2G for 5 days or 34 days as well as for 34 days plus 5 days with an interval of 39 days between two rotations. Control rats were kept in a centrifuge room. Radioimmununoassay, quantitative and semi-quantitative immunocytochemistry and in situ hybridization were used to evaluate: a) VP concentration in the pituitary posterior lobe (PL) and in plasma; b) the number of VP-, OT- and TH-immunoreactive neurons in the SON; c) the optic density of VP-, OT- and TH-immunoreactive materials in cell bodies (SON) and distal axons (PL), d) the optic density of VP and OT mRNAs signals (S35) in the whole SON on microfilms. According to our data, VP neurons were strongly activated during HG (5 days or 34 days) that was manifested in the functional hypertrophy of the neurons, greatly increased concentrations of VP mRNA in the SON and VP in plasma, the onset of the TH expression. The neurons showed initially (5 days) the functional insufficiency (VP release > VP synthesis) followed by their adaptation (subsequent 29 days) to the increased need in VP (VP release < VP synthesis). No reaction of VP neurons was observed to repeated HG. In contrast to VP neurons, OT neurons did not react to short-term HG or showed functional depression after the long-term treatment.

Journal Article↗
PubMed2004

[University qualifying work (dissertations), their current registration, electronic access and related technical, administrative and legal questions].

Many countries (USA, Australia, Canada, Latin America, Spain, France, SRN) have national or international systems (e.g. Networked Digital Library of Theses and Dissertations--NDLTD), which openly (NDLTD) or commercially (University Microfilm International--UMI) present up to 50% of master dissertations and doctoral theses in a full text form. Such systems are in agreement with legal regulations of the given country and the author is the only holder of the work--of the dissertation. Authors are at the same time informed that dissertation represents a university document, which presents results of the given scientific community and it should be therefore distributed free of charge. Presentation is also the matter of honour of the author and his university. In the contemporary Czech Auctorial Law (No. 121/2000 Sb.) dissertation is considered as not fully defined "Educational work" and from the practical point the duration of necessary storage is not solved. For the contemporary worldwide conversion to electronically presented dissertations, the necessary technical and library standards has been prepared with the first positive experience. The supplement of the Auctorial and University Law appears to be necessary. It is inevitable to be prepared for that situation before the Czech Republic will join EU.

Academic Dissertations as Topic↗
PubMedDate not supplied

[Patterns of swimming of cercariae in some trematode species].

Swimming activity of cercariae in the trematode species Cryptocotyle lingua, Himasthla elongata, Maritrema subdolum, and Cercaria parvicaudata (Renicola sp.) is studied using video microfilming. The larvae of C. lingua demonstrate a typical intermittent swimming with regularly alternating periods of active movement and passive floating. The duration of both periods during the first 30 min of cercaria's life retains equal, and later the passive period becomes longer. In 15 h the duration of the active period is 0.5-1 s and the passive one--20-30 s. The cercariae of H. elongata during the first 10-15 min of their free life make short stops (1-2 s) in every 10-15 s of swimming. Later these stops become rare and their duration reduces to 0.5-1 s. The cercariae of M. subdolum and C. parvicaudata are continuous swimmers, having left the molluscan host they move persistently. If stops take place they are very rare (one case in 5-15 min) and very short (0.5-1 s). The movements of cercariae body and their tail during swimming are similar in all species studied. The proximal part of the tail undulates in lateral plane, and the middle and distal parts of this organ in the top view circumscribe a figure of eight. In the side view the middle and distal parts of the tail being rotate form a figure like a screw. The cercariae move along the screw axis. The linear swimming rate in the beginning of cercariae's life is 4.8 mm/s for C. lingua, 2.4 mm/s for H. elongata, and 0.35 mm/s for M. subdolum and C. parvicaudata. By the aging the cercariae swimming rate decreases down to the full cease of swimming activity, and the larvae sediment onto the bottom. The age dynamics of swimming rate is different in cercariae of different species and is determined by the morphological functional features of the larvae.

Animals↗
PubMedDate not supplied

[Heterogeneity of the population of Escherichia coli thr- by assimilation of 3H-threonine].

The incorporation and spatial localisation of [3H]threonine in the cells of Escherichia coli RP 477 (leu-his-thr-B1-) were studied using the techniques of radiometry and adsorption electron-microscopic autoradiography with additional time-lapse microfilming to follow up the growth of the population. The strain was shown to be heterogeneous in its metabolic, reproductive and morphological (cell diameter) characteristics; a generative cluster was revealed. Indirect data indicated that the so-called "resting" cells were functionally active.

Escherichia coli↗
PubMed1989

Preservation of the biomedical literature: an overview.

The National Library of Medicine began to preserve its collection many years ago. This article presents a brief review of NLM's early conservation and microfilming programs, and describes the current activities of the library's new Preservation Section. Also mentioned are the complementary efforts of NLM staff who are involved in research into electronic imaging and the campaign to increase the use of alkaline paper in medical and scientific publishing. Goals of the National Preservation Plan for the Biomedical Literature are summarized and a report on progress in implementing the plan is provided. Results of the preservation needs assessment described in the accompanying article by Kirkpatrick are briefly analyzed. Recent efforts of the Commission on Preservation and Access, the National Endowment for the Humanities, the Research Libraries Group, and several international associations are described in terms of their potential benefit to preservation of the biomedical literature. The need to monitor new preservation technologies and preserve materials in audiovisual and electronic formats is emphasized. It is argued that with enough coordination, cooperation, and willingness among health sciences libraries to share the costs, the goal of preserving all of the important biomedical literature can be accomplished.

Books↗
PubMed1989

Selection for preservation: considerations for the health sciences.

Just as no health sciences library can afford to collect every work on a subject, neither can any health sciences library afford to preserve every item that is added to its collection. In decision making for collection development, health sciences libraries apply a set of selection criteria. Those same criteria have direct application in selection for preservation decisions. This paper summarizes the literature of selection for preservation, describes the scholarly record of biomedicine, and presents criteria for selection for preservation decisions. The preservation priorities statement for microfilming of monographs and serials in the National Library of Medicine collection is included as an appendix.

Corrosion↗
PubMed1978

[Plaque indices].

The objective quantitative evaluation of the extent of plaques is necessary for epidemiologic studies and for the estimation of the effects of various cleaning methods and agents. Numerous indices have been elaborated for this purpose. Relation planimetry is used for the detection and exact evaluation of small differences. The surfaces are measured with a compensating planimeter, the slides to be evaluated being projected on a white sheet by means of a microfilm reader. In this way, the plaque covered surfaces are determined as percentages of the total surfaces.

Adolescent↗
PubMed1986

[Cyclicity, reversibility and compensation of magnetobiological reactions in isolated cells and tissues].

Cell sensitivity to a constant magnetic field (CMF) of 100 = 200 Oe was studied on a fibroblast culture using time-lapse microfilming. It was expressed in the phasic development of the motility of cells, intracellular structures and inclusions: a short-term latent phase (10-15 min), an excitation phase (1.5-2 h) and a suppression phase (up to the end of exposure). After field removal the return of cells to the initial state with a slight excess (in 1.5-2 h) was noted. The phasic development, reversibility and compensation of magnetobiological reactions were later on confirmed in studies on the inhibition in CMF of 400-600 Oe of the activity of succinate dehydrogenase and peptidase in isolated surviving rat skeletal muscles, liver and kidney as well as on a model of the reaction of a cytopathogenic effect of lymphocytes from patients with rheumatic fever on human embryonic fibroblasts where a noticeable effect of inhibition with the CMF action on the system of lymphocytes-fibroblasts and, on the contrary, of its activation with adding to fibroblasts lymphocytes preexposed in CMF of 400-600 Oe for 1 and 24 h were revealed and interpreted as supercompensation of the inhibited enzymatic activity of immunocompetent cells. The phasic development, reversibility and compensation of magnetobiological reactions should be necessarily taken into account in working out magnetotherapy.

Adaptation, Physiological↗
PubMed1979

[Blood flow in skeletal muscle microvessels in normoxia and arterial hypoxemia (microcinematographic studies)].

Vital microfilming revealed peculiarities of blood flow in microvessels of 2-5-micron diameter under relatively resting conditions, in normoxia, as well as the microcirculatory response to hypoxia (breathing with mixture of nitrogen and 6-8% oxygen for 5 min), in intact temporal muscle of rat. The average blood flow velocity in normoxia was 1.14 +/- 0.04 mm/sec in capillaries and 2.43 +/- 0.08 mm/sec in terminal arterioles. Breathing with the hypoxic mixture decelerated blood flow in 75% of the vessels. The blood low velocity in the muscle capillaries correlated with arterial blood pressure.

Animals↗
PubMed1970

The Osler Library: today and tomorrow.

The Osler Library's purpose is to build a collection capable of supporting research in the history of medicine. The major acquisition area is material published from 1960 to 1968. Out-of-print material is acquired on microfilm. The Library contains all pre-1850 monographs, transferred from the Medical Library, and all new monographs from 1850 to 1899 are housed there. The catalogs are described, together with special files, including chronological, journal article index, and publishers' lists index.The place of the original Osler collection is discussed, as are methods by which the collections are preserved. The Library hopes to become a deposit center in Eastern Canada for historical medical material.The administration and organization of the Library are described.

History of Medicine↗
PubMed1966

Topics in library technology: copying techniques.

Photocopying applications in the library include the combining of previously separate material, the separation of a single item into two or more of its parts, and the selection of parts of existent material by the use of overlays. The production of catalog cards, the creation of sheet material (new book lists, reference bibliographies) from card-form materials, an Index Medicus-derived alerting service, and overdue notices copied from charge cards are among the applications exemplifying these general types. Larger-scale operations employing microfilm are noted. The distinction between copying and printing, in the light of equipment advances, is discussed.

Copying Processes↗
PubMedDate not supplied

[Conformational fluctuations in chloroplasts].

Characteristic features of conformational changes in chloroplasts have been studied by microfilm technique at BMI-13 installation. The oscillatory character of changes in chloroplast cross-section area in time, determined earlier by the tele-lazer microscopy technique, has been confirmed by our data. When chloroplasts are simultaneously seen in the microscope it is possible to observe their synchronous oscillation. The stationarity check of conformational changes shows that is a non-stationary process in the general case. So it is concluded that the standard technique of analysing accidental non-stationary processes can be used for study of conformational changes in chloroplasts provided that the corresponding parts of their kinetics are selected or trends are eliminated depending on the type of non-stationarity.

Biometry↗
PubMed1984

[Erythrocyte concentration in vessels of the microcirculatory bed of the mesentery of the white rat (according to the results of in vivo microcinematography)].

The red cells velocity and hematocrit value were studied with high-speed microfilming in microvessels of albino rat mesentery. Decrease of the red cells velocity and increase in the number of microvascular branching were followed by a decrease in the hematocrit value: 20% in the precapillary arterioles and 16% in capillaries. The concentration of erythrocytes increased to 26% in venules. The magistral communication between arterioles and venules has a specific place among microvessels. These channels are relatively wider, the red cells velocity is high (0.9 mm/sec) as well as the hematocrit value (23%). Variation of hematocrit value in capillaries is not solely the function of their volume but also the function of their position in capillary net.

Animals↗
PubMed1983

[Use of the dia-contact method in ophthalmology. A new method of fluorescein angiography presentation].

An innovative presentation of fluorescein angiograms on radiographic film, called "dia-contact", is described. Photographs are produced by the classical procedure of contact-printing on subtraction film and are of very high quality resolution. Less expensive than conventional prints, the resultant document is easy to copy and file. The reading of this document with the help of two + 10 lenses, allows a sequential analysis of the angiogram and a stereoscopic interpretation alternatively. The image can be enlarged without loss of resolution by means of a microfilm reader device. This method requires a certain amount of self discipline, in that a new habit must be learned. However it rapidly proved itself invaluable in the author's daily practice.

Fluorescein Angiography↗