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At least 235 records · Page 13Linked to original sources

Posterior chamber phakic intraocular lens for moderate myopia and hyperopia.

BACKGROUND: As part of the United States Food and Drug Administration Phase III clinical trial, patients were implanted with the STAAR posterior chamber phakic intraocular contact lens (ICL). The trial is designed to test the safety and efficacy of this new lens for the treatment of moderate-to-high myopia and hyperopia. METHODS: Data were collected from 20 hyperopes--mean preoperative spherical equivalent, +5.55 D, and 65 myopes-mean preoperative spherical equivalent, -8.42 D, who were implanted with ICLs in our clinic, from November 1998 to March 2000. RESULTS: Postoperatively, 40% of the hyperopic eyes were 20/20 or better without correction and 80% of the eyes 20/40 or better without correction, with a mean spherical equivalent of +0.06 D. One hyperopic lens was explanted and no adverse events were reported. Postoperatively, 52.31% of the myopic eyes were 20/20 or better without correction and 92.3% of the eyes were 20/40 or better without correction, with a mean spherical equivalent of -0.31 D. No lenses were explanted and one was treated for angle closure. CONCLUSIONS: The STAAR Collamer ICL is a reasonably safe and effective procedure for the treatment of moderate-to-high refractive errors.

Adult↗

Surgical correction of hyperopia: a new experimental approach using X-incision and suture technique in rabbits.

BACKGROUND: A new experimental surgical technique to correct hyperopia by steepening the central corneal curvature was performed on the eyes of rabbits. METHODS: After X-shaped incisions at four quadrants of the paracentral cornea, four deep, transverse interrupted sutures were placed across the incisions and the knots were tightened to compress the corneal tissue in the direction of the suture. Twenty-three eyes of 12 albino rabbits were divided into group A (7 eyes) with a 4-millimeter diameter clear zone, group B (9 eyes) with a 6-millimeter diameter clear zone, and control group C, consisting of 7 contralateral eyes of group A without any incision or suture. RESULTS: There was significant (p < .01) steepening of the central cornea as measured by the keratometer at postoperative 8 weeks in group A (+1.88 diopters) and group B (+1.68 D) compared with that of the control group C (-3.44 D). The difference in effect of hyperopic correction between groups of A and B was not statistically significant. CONCLUSIONS: This procedure serves only as an experimental model of corneal response to incisions and sutures and is not for use in human corneas.

Animals↗

Hyperopia, anisometropia, and irregular astigmatism in a patient following revisional radial keratotomy.

We present a patient who underwent bilateral radial keratotomy (RK) followed by a bilateral revisional RK for undercorrection. After the second procedure, the patient had a severely flattened left cornea, with marked hyperopia and irregular astigmatism. The right eye, however, remained myopic, causing extreme anisometropia. We hypothesize that the different results in these two eyes may have been due to a critical number of damaged left corneal stromal fibers. Patients undergoing revisional RK or requiring additional incisions may be at increased risk for such a complication.

Anisometropia↗

[Comparison of results of photorefractive keratectomy and laser in situ keratomileusis in the treatment of hyperopia using a flying spot eximer laser].

PURPOSE: To evaluate the results of photorefractive keratectomy (PRK) and Laser in situ keratomieusis (LASIK) in eyes treated with hyperopia. PATIENTS AND METHODS: group 1 consisted of PRK-operated eyes, group 2 consisted of LASIK-operated eyes. In each group 20 eyes of 20 patients were listed. The average age in Group 1 was 33.4 +/- 8.4 year, while in group 2 it was 34.2 +/- 7.9 year. Refractive treatments were carried out with the Asclepion Meditec MEL 70 G-Scan flying spot excimer laser, LASIK flaps were created by the Moria CB manual microkeratome. RESULTS: In group 1, pre-operative refraction was +4.2 +/- 1.1 D (SE = spherical equivalent), in group 2 it was +4.8 +/- 1.21 D. Six months following surgery refraction was +0.35 +/- 0.12 D (SE) in group 1, while +0.38 +/- 0.14 D (SE) in group 2. The uncorrected visual acuity was 0.92 +/- 0.04 in group 1 and 0.91 +/- 0.01 in group 2.85% of eyes in group 1 and 95% of eyes in group 2 had a 1.0 uncorrected visual acuity. In group 1, 95% of the eyes were within +/- 1.0 D of targeted refraction, while in group 2, 100% achieved this. Best spectacle corrected visual acuity (BSCVA) did not change in 90% of group 1, while in 5% it increased by 1 and in the remaining 5% decreased by 1 Snellen line. In group 2. BSCVA remained unchanged in 85% of eyes, while in 10% it increased and in 5% decreased by 1 Snellen line. In group 1, glare was reported in 4 eyes, while in group 2.5 eyes reported postoperative glare, mainly during night driving. CONCLUSION: Effectivity, predictability and safety was good in both treatment groups. Results of hyperopic eyes below +6.0 D of preoperative refraction were not dependent on the type of operation (PRK or LASIK).

Adult↗

[Complications of epikeratophakia in correction of aphakia, myopia, hyperopia and keratoconus].

Epikeratophakia for the correction of aphakia, myopia, hyperopia and keratoconus has overcome many of the objections to earlier lamellar refractive procedures (keratophakia and keratomileusis), such as the lamellar dissection of the recipients' healthy cornea over the visual axis and the need for expensive surgical equipment. It is reasonably reversible and repeatable. The complications observed in a series of 119 operations performed at the 2nd Department of Ophthalmology, University of Vienna, are discussed and compared with those reported in the literature. Serious complications, both intraoperatively and in the early and late postoperative period, that permanently threaten the patients vision are rare. Predictability and loss of effect in a significant percentage of myopic cases, caused by lack of precision during manufacturing of the lenticules and individual wound healing, makes careful patient selection mandatory.

Adult↗

A pedigree of cervical stenosis, brachydactyly, syndactyly, and hyperopia.

Cervical myelopathy due to developmental cervical canal stenosis occurred in a 13-year-old boy. The patient's father and aunt also had an abnormally small cervical canal, although both were asymptomatic. The patient and his family had many congenital anomalies including hereditary brachydactyly, syndactyly, and hyperopia. The association of these anomalies seems not to have been previously reported in the literature.

Abnormalities, Multiple↗

Correction of hyperopia following radial keratotomy: quantification in human cadaver eyes.

Overcorrection is a significant complication following radial keratotomy (RK). This study using human cadaver eyes demonstrates that the use of interrupted sutures placed across radial incisions coincident with a 7-mm optical zone mark can induce a wide range of central corneal steepening and can therefore correct varying amounts of hyperopia following RK. A case presentation confirms the effectiveness of using interrupted sutures to steepen the cornea following RK, but it also shows that significant regression of the effect must be considered at the time of suture placement. Since placement of interrupted corneal sutures is a routine procedure, it is a very convenient technique for treating overcorrection following RK.

Adult↗

Progressive hyperopia in radial keratotomy. Long-term follow-up of diamond-knife and metal-blade series.

In an earlier report, the authors demonstrated a trend toward progressive hyperopia in radial keratotomy (RK) patients examined between one and three to four years postoperatively. In those 109 cases, the surgeries were performed using a metal-blade instrument. In the following study, the metal-blade series was updated to a total of 225 procedures, and a more recent series of 300 procedures performed on 228 patients was examined in which a diamond-knife cutting instrument was used. Patients had uncorrected visual acuity determination, cycloplegic refractions with best corrected visual acuity measurements and keratometry measurements. The authors demonstrated a hyperopic shift in the distribution of postoperative spherical equivalent (SE) values across time such that higher proportions of cases in both metal-blade and diamond-knife series were at least 1.0 diopter (D) away from emmetropia at 24 and 48 months than was the case at 12 months after surgery. Regression analysis determined that none of the preoperative or surgical variables known to affect refractive outcome of RK (alone or in combination) could account for the changes in refraction seen during the course of postoperative time. In general, changes in keratometry paralleled refractive changes, but were somewhat smaller in magnitude.

Cornea↗

Cyclotherapy in the treatment of symptomatic latent hyperopia.

Many practitioners have long been frustrated with traditional treatments of symptomatic latent hyperopia (fogging techniques, bifocals, etc.). A technique employing short-acting cycloplegia has been developed which provides rapid relief of symptoms by promoting full correction of latent refractive error. Fifteen symptomatic subjects ages 3-40 were diagnosed as latent hyperopes with the aid of 1% cyclopentolate, and subsequently recyclopleged utilizing full correction in constant wear spectacles. Acuity was maintained via slow diminution of cycloplegia. Short-term and long-term follow-up, with continued use of spectacles or contact lenses, revealed rapid and complete resolution of symptoms and restoration of visual efficiency in each case. Cyclotherapy offers both practitioners and patients an efficient, rapid-acting, and satisfying alternative treatment for this vexing accommodative anomaly.

Accommodation, Ocular↗

The relation of astigmatism and hyperopia (more effective plus).

Two-hundred and ninety eight high astigmatic refractive errors are reviewed in order to establish the clinical and theoretical relationship of high astigmatism to hyperopia. All methods of analysis demonstrated that high astigmatism and greater plus power are related.

Adolescent↗

Holmium:YAG laser thermokeratoplasty for hyperopia.

Holmium:YAG laser thermokeratoplasty (LTK), a procedure using a solid-state infrared laser to treat hyperopia, was performed on 10 patients in phase I and 16 patients in phase II--in a total of 29 eyes at the Hunkeler Eye Clinic. Phase II was redesigned after phase I results showed undercorrection and regression. The follow-up period ranged from 1 to 24 months (mean 10.9 months). A total of 79% of phase II patients were within +/- 1.00 D of intended correction at the 6-month visit. Looking at both phases together, no patients had J2 or better near vision preoperatively, but 75% had J2 or better at the 6-month visit. A total of 43% of eyes in phase II lost 1 line and 7% lost two lines of best spectacle corrected visual acuity due to induction of irregular astigmatism. The surgical challenges are to insure appropriate centration of the procedure about the optical axis. Concerns about regression and stability will be defined as these patients are followed through their 2-year visits.

Cornea↗

Bilateral microphthalmos with poor visual acuity, high hyperopia, and papillomacular retinal folds in siblings.

Ophthalmological examinations were carried out on a 4-year old girl and her 2-year-old brother who have had poor visual acuity since birth. A consanguineous relationship was found between the parents. Both children had bilateral microphthalmos, poor visual acuity, high hyperopia, and papillomacular retinal folds. No ocular coloboma or systemic abnormality was found. We believe that the ophthalmic findings in these patients are rare.

Child, Preschool↗

Endothelial cell studies in patients after photorefractive keratectomy for hyperopia.

PURPOSE: To report central and peripheral corneal endothelial cell studies performed as part of the VISX hyperopic photorefractive keratectomy (PRK) clinical trial. METHODS: During this prospective, multicenter clinical trial, which was part of an FDA investigation, endothelial cell specular microscopy was done at five centers. Non-contact central and peripheral cell density, percent hexagonality, and coefficient of variability of cell size were obtained using the Konan Noncon Robo SP-8000FA with BAMBI analysis software. Data were gathered at baseline and at 1, 6, and 12 months after hyperopic PRK. RESULTS: Analysis of results of 171 eyes demonstrated no statistically significant detrimental changes in the corneal endothelium at any postoperative time point. The statistically significant changes noted were interpreted as an improvement in cell morphology and were attributed to the cessation of contact lens wear following treatment. CONCLUSION: Hyperopic PRK with the VISX STAR S2 Excimer Laser System produced no statistically significant adverse effect on the corneal endothelium.

Adult↗

[On hyperopia].

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Hyperopia↗