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[Unilateral exophthalmos caused by organized hematoma of the orbit--report of a case (author's transl)].

The authors reported a case with unilateral proptosis of over ten years' duration due to organized hematoma of the orbit. It has generally been accepted that any given hemorrhage within the orbit can be resolved in a relatively short period of time. Persistent intraorbital hematoma, therefore, in the form of organized hematoma is very unusual in incidence and has been reported very few in the literature. Our patient presented himself with a ten-and-several-year history of unilateral exophthalmos, limited ocular movement and decreased visual acuity on the involved side. There was no specific symptom when compared with the other intraorbital tumors. Total resection of the tumor was performed through transcranial frontozygomatic approach. Histopathologic examination revealed evidence of organized hematoma without definite sources of bleeding such as microangioma, microaneurysm or arteriovenous malformation. Retrospective review of history failed to uncover episodes of hemorrhagic tendency or direct trauma to the head or the orbit. Subsequently a diagnosis of spontaneous organized hematoma was made. Great emphasis was laid on the fact that CT-scan was one of the most useful diagnostic tools. Our surgical approach was introduced and discussed.

Adult↗

Cranial tumors in aged cattle causing Horner's syndrome and exophthalmos.

An 11-year-old Jersey cow and a 9-year-old Holstein cow were examined for complaints of progressive exophthalmos. Additionally, signs of unilateral Horner's syndrome and reduced air movement through the nasal passages on the affected side were observed. In both cases, a poor prognosis was given due to suspected neoplasia. At 2 and 6 months, respectively, after initial examination, these cows were killed and post mortem examinations of the affected tissues were performed. The diagnosis for the Jersey was sclerosing respiratory epithelial adenocarcinoma and for the Holstein was squamous cell carcinoma. The clinical signs, differential diagnosis, and the progression of the disease were discussed.

Adenocarcinoma↗

Pulsating exophthalmos: orbital tumors in siblings.

The extremely rare occurrence of sibling brothers with left pulsating exophthalmos has been presented with very similar plain film and CT scan findings. Other patients presented demonstrate the strong familial trend of neurofibromatosis, the multiplicity of lesions, the progression of lesions. Genetic counseling is indicated, together with educating the patient and family as to further neurologic deficits which may develop. On-going evaluation at intervals is indicated. Significant cases should only be approached surgically with the realization of the seriousness of what both the patient and doctor may encounter. Surgery, unfortunately, usually cannot offer much help. An interdisciplinary approach with the surgeon, plastic surgeon, neurosurgeon, and ophthalmologist offers a safer approach.

Adolescent↗

The effect of anterior orbital decompression on motility in thyroid exophthalmos.

Nineteen orbits from 13 patients with endocrine exophthalmos were effectively decompressed into the maxillary and ethmoid antra through an anterior orbitotomy. Six patients with preoperative diplopia had improved ocular ductions and return of binocular single vision in functional positions. Diplopia was not induced in five patients with normal pre-op motility. In one patient with active orbitopathy, a large postoperative esotropia was caused by worsening of medial rectus inflammation. This approach appears to lessen the incidence of postoperative diplopia and may make subsequent extraocular muscle procedures unnecessary.

Adult↗

[Leiomyosarcoma metastatizing to the sphenoid bone presenting exophthalmos: a case report].

A rare subcutaneous leiomyosarcoma metastatizing to the sphenoid bone and presenting exophthalmos is reported. A 56-year-old female presented with protrusion of the right eye and a slowly growing lump on the right temporal region. Six years previously, she had undergone removal of a subcutaneous mass in the back, which was histologically diagnosed in another hospital as leiomyosarcoma. She had undergone four other operations, including removal of local recurrences and a right renal metastasis. On admission, physical examination showed no neurological deficits. Craniogram revealed an osteolytic lesion without marginal sclerosis in the right sphenoid bone. CT showed an inhomogeneously enhanced mass with irregular expansion of the diploic space, which was partly invading the right orbit. MRI demonstrated an extradural mass in the right sphenoid region, which was slightly low-intense in T1-weighted image, high-intense in T2-weighted image, and inhomogeneously enhanced by Gd-DTPA. Right external carotid angiogram showed a highly vascular stain fed by meningeal arteries. Radionuclide bone scintigram showed multiple high-uptake areas in the left femoral head, the ribs, and the sphenoid bone. Preoperative embolization of the tumor vessels fed by the external carotid artery was performed. Following this procedure, the tumor stain disappeared completely. The tumor was totally excised with minimal bleeding through an orbitozygomatic approach. The tumor was loosely adherent to the dura and periorbit. The bone defect was covered with a methylmethacrylate resin plate. the histological examination demonstrated fascicular arrangement of the spindle shaped cells with mitotic figures. Immunohistochemical studies showed that most tumor cells were positive for actin and myosin, but negative for desmin.(ABSTRACT TRUNCATED AT 250 WORDS)

Exophthalmos↗

[Basedow exophthalmos: lipectomy or orbital expansion?].

Graves' disease is due to mismatching of the orbit and its contents. Primary muscular hypertrophy is often accompanied increased intraorbital pressure due to obstruction of the venolymphatic drainage at the orbital apex. In moist cases, the fat undergoes minimal volumetric and structural changes. Among the numerous techniques proposed for orbital decompression the solution which allows the greatest orbitoperiosteal expansion while preserving the integrity of the orbital fat is valgus displacement of the malar bone combined with resection of the lateral wall and recession of the inferior and medial orbital walls. This technique, which can be adapted to the severity of each case, is performed via a infraciliary transpalpebral facial incision. It is easier to perform than via a coronal incision. It should be preferred to trans-sinus techniques which have a limited and dangerous action (considerable incidence of postoperative diplopia) and decompression lipectomy, which is difficult to perform, with a light risk and, furthermore, does not take into account the fundamental physiological role of the orbital fat nor the essentially muscular pathogenesis of exophthalmos.

Adult↗

[Unusual course of a malignant exophthalmos].

In spite of careful choice of therapy for the individual case, including all the methods used hitherto, such as total thyroidectomy, hypophyseal castration by surgery or irradiation, the prognosis of malignant exophthalmos is very unfavorable. The unusual intense and persistent growth of fatty and connective tissue in the orbit was striking in our patient. The forward thrusting tissue could only be brought to a standstill by X-irradiation of both orbits. The hyperthyroidism itself only showed improvement months later.

Adipose Tissue↗

[Mucocele: a cause of exophthalmos originating blindness].

Inflammatory exophthalmos with visual loss due to optic atrophy is reported in a 45-year-old man. Computed tomography showed an ethmoido-frontal mucocel. This single case stresses the severe complication of a mucocel like optic nerve head atrophy. The different tools for diagnosis and treatment are also emphasized.

Blindness↗

Treatment of exophthalmos by orbital fat removal.

Decompression of the orbit by removal of fat is a safe method to obtain functional and aesthetic improvement in exophthalmos disease. In comparison with traditional orbital wall decompression, the complication rate is low.

Adipose Tissue↗

[Non-sarcomatous bilateral exophthalmos disclosing acute myeloblastic leukemia in children].

The authors report a bilateral exophthalmos due to a leukemic infiltration of the orbital lacrimal glands during an acute myeloblastic leukemia in a ten-year-old boy. This rare orbital localization revealed the leukemia. It was not a granulocytic sarcoma. Its importance leads to the extraction of the lacrimal glands in order to prevent the eyes from corneal perforation.

Child↗

The value of computer tomography, orbital venography and carotid angiography in the diagnosis of exophthalmos.

On the bases of 25 patients examined by orbital venography, computer tomography, (CT scanning) and sometimes carotid angiography, the diagnostic value of each of these methods is evaluated. The data obtained are compared with the corresponding information from the literature. In view of the findings it can be stated that CT scanning can be regarded as the primary neuroradiological examination in cases of exophthalmos. Orbital venography gives supplementary information in cases of varices and venous malformations. Angiography is the method which supplies the maximum of information when cavernous sinus fistulae are clinically suspected. With reference to 3 patients it is explained that in such selective angiography of the internal and external carotid and the vertebral artery is indicated.

Adolescent↗

[Exophthalmos and cranial neuropathy as a form of presentation of Wegener's granulomatosis].

The cases of three patients with Wegener's granulomatosis presenting as exophthalmos and cranial neuropathy are reported. In the first patient's symptoms were secondary to the presence of a retro-orbital mass. In the second and third patients there was dissemination of neighboring granulomatous processes. Paranasal sinuses were involved in two patients, but clinical manifestations were evident in only one. Full remission was achieved in all three. Two patients had been received immunosuppressant therapy for inflammatory processes evaluated a posteriori in the context of Wegener's granulomatosis. The immunosuppressant treatment seems to have conditioned this unusual clinical presentation.

Adult↗

Comparison of ultrasonography, computerized tomography (EMI scan), and radiographic techniques in evaluation of exophthalmos.

A series of 342 consecutive patients with unilateral exophthalmos of confirmed etiology have been studied with a combination of clinical investigative techniques. High resolution B-scan ultrasonography and computerized tomography proved to be the most valuable tests for detecting orbital tumors and inflammatory conditions. Ultrasonography demonstrated primary orbital tumors but failed to show intracranial and some secondary tumors. Computerized tomography demonstrated primary, secondary, and intracranial tumors but not cystic masses. Inflammatory conditions such as Graves' disease and pseudotumor were characterized by ultrasonography also, while computerized tomography was not reliable for this. Correct diagnosis of orbital abnormalities in this series was 82% with ultrasonography and 72% with computerized tomography. Combined accuracy of these two complementary tests was 97% for tumor diagnosis. Conventional radiography and polytomography revealed secondary bony changes but not primary orbital tumors and inflammation. Orbital venography and arteriography had a low yield with tumors but were essential for demonstrating arteriovenous abnormalities. Orbital diagnosis has been improved significantly with the two newer techniques of ultrasonography and computerized tomography.

Computers↗

[Orbital decompression in exophthalmos due to thyroid disease. Report of 69 cases].

Dysthyroid exophthalmos is due to mismatching of the orbit and its contents, essentially due to muscle enlargement, and, to a lesser degree, fat volumetric changes. Surgical treatment is designed to expand the orbital volume by bone removal or to reduce orbital contents by fat removal, or a combination of the two techniques. Our series consisted of 69 patients who underwent orbital decompression for proptosis, with osteotomy (12 cases) or associated with fat removal (57 cases). We obtained good results for all cases, and did not encounter any complications. Several factors now appear to play a role in the choice of surgical technique, particularly the preoperative radiologic (CT) examination which determines the muscular and fat involvement, wall orbital changes and appearance of the sinuses. Orbital fat removal seems to be useful in proptosis reduction in those cases in which fat is more involved and easy to remove. Anthral ethmoidal decompression is the best technique in the case of dysthyroid optic neuropathy.

Adult↗

Dural arteriovenous malformation with false aneurysm and exophthalmos. A successfully treated case.

A case of dural arteriovenous malformation with giant non-traumatic false aneurysm in the left middle fossa is reported. A 10-year-old female patient was admitted to our hospital with pulsating exophthalmos of the left eye, which was successfully treated by ligation of the main feeder and finally by the radical excision of the dural AVM and false aneurysm. False aneurysm of non-traumatic origin is so rare that only two cases were detected in the literature (Reina et al., Sakaki et al.), and no previous case of false aneurysm complicated by dural AVM seems to have been reported.

Child↗

Increased pressure of dilated episcleral veins with open-angle glaucoma without exophthalmos.

Six unilateral cases and one bilateral case of dilated episcleral veins with elevated intraocular pressure without exophthalmos are described. Episcleral venous pressure measured on six unilateral cases showed increased pressure in the affected eye compared to the other eye and to normal controls. Two eyes had typical glaucomatous disc and visual field changes. Five had more optic disc cupping and pallor in the eye with the elevated episcleral venous pressure and intraocular pressure. A thorough work-up, including orbital venography in two unilateral cases, carotid arteriography in one and episcleral fluorescein angiography in five cases, failed to show venous obstruction or direct arterio-venous communications. The different diagnoses are discussed. This condition should be considered in unilateral or asymmetrical intraocular pressure elevation and in those patients with chronically red eyes without discharge.

Aged↗