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At least 235 records · Page 13Linked to original sources
PubMed1991

[The dynamics of the immunological indices during the treatment of recurrent erysipelas with the new immunostimulant bemitil].

Bemitil, administered orally in a dose of 0.25-0.5 g a day for 5-7 days at the acute period of the relapse of erysipelas as an immunostimulant, enhanced the effectiveness of the basic therapy including antibiotics, anti-inflammatory and antiallergic drugs, vitamins, plasma-substituting fluids and saline solutions, as well as ultraviolet irradiation of the focus of lesion. Bemitil therapy was associated with an increase in the number of T-lymphocytes, normalization of the balance between the peripheral lymphocyte preparations, an increase of blood serum levels of IgA and IgM.

Adjuvants, Immunologic↗
PubMed1991

[Elephantiasis nostras. A rare complication to erysipelas].

A case of elephantiasis nostras in a lower limb is presented. A thorough programme of investigation could only reveal a single episode of erysipelas as the possible etiological origin. The therapeutic possibilities are briefly reviewed. The most important are early institution of adequate antibiotic treatment and antibiotic treatment of every recurrence of disease.

Adult↗
PubMed1991

[Effect of hemodynamic disorders on the course of erysipelas of the lower extremities].

The indices of peripheral circulation in 45 patients with erysipelas of the lower extremities were studied by means of Doppler ultrasound, sonography and tetrapolar rheography in dynamics. It was established that in stable disorders in venous blood flow, disease recurrency developed 2 times more often than in patients with normalized circulation.

Adult↗
PubMed1990

Plasma fibronectin level in erysipelas.

The level of plasma fibronectin was measured to 20 patients suffering from erysipelas and 10 normal controls. Significantly low levels of plasma fibronectin were detected in the group of patients (134 +/- 7.4 g./ml) in comparison to the normal control group (352.6 +/- 42.9 g./ml) p less than 0.001. This could be of prognostic value and also of therapeutic one. Some centres have tried fibronectin replacement therapy in the treatment of critically ill patients with severe bacterial sepsis.

Adult↗
PubMed1990

[The treatment of patients with the hemorrhagic form of erysipelas by using amben and parmidine].

Amben (fibrinolysis inhibitor) and parmidin (bradykinin inhibitor) were used as pathogenetic treatment of 38 and 36 patients with hemorrhagic erysipelas respectively. Early amben treatment proved clinically rather effective and was accompanied by normalization of fibrinolysis and kallikrein-kinin system. Parmidin treatment resulted only in pain control, other subjective signs, normalization of the kallikrein-kinin system while fibrinolysis activity was maintained at former levels.

4-Aminobenzoic Acid↗
PubMed1990

[The diagnostic and prognostic significance of the level of circulating immune complexes in patients with recurrent erysipelas].

The authors analyzed data of 856 case histories of patients suffering of erysipelas. Methods of discriminative analysis were used. It was established that an increase of circulating immune complexes to 6.0 g/l and more and maintaining of this index at such level by the moment of discharge of the patient and in the inter-recurrence period proved prognostically unfavourable and evidenced high probability of recurrence. The presence was established of a correlation between the level of circulating immune complexes, number of T-lymphocytes, level of sulfhydryl groups of blood deproteinate, reaction of antibody activity inhibition.

Antigen-Antibody Complex↗
PubMed1985

Coagulation and fibrinolytic systems during the course of erysipelas and necrotizing fasciitis and the effect of heparin.

Necrotizing fasciitis (NF) is a grave infection of the skin leading to gangrene of the integument and often having a complicated and prolonged course. Studies on blood coagulation and fibrinolysis were done in 15 patients with NF and compared with 5 cases of erysipelas (E). In both conditions local fibrin deposition occurred initially in their course, but it was quantitatively more pronounced in NF than in E. Fibrinolysis decreased and stayed low at the site of NF up to 5 months (median) after discharge from hospital. Fibrinogen and activities of several plasma serine proteinases modifying coagulation were increased during the course of both diseases and even at the follow-up. Factor XII was decreased during the first week in E but a transient drop was present in NF only on days 3 and 4. The treatment of NF consists of high doses of appropriate antibiotics instituted early in its course. A beneficial effect of 300-500 IU heparin/kg/day was suggested from this open study. The hard induration preceding the appearance of skin gangrene was inhibited, if heparin was given early in the course of NF. We conclude that the enhanced fibrin deposition and vascular occlusions in the skin are the basis for most complications present in NF.

Adult↗
PubMed1989

Study of granulocyte function of peripheral blood in recurrent erysipelas.

The Boyden chamber technique, the NBT reduction and Candida killing test were carried out on 51 patients with recurrent erysipelas to investigate the non-specific immune response. A statistically significant difference was not observed between the patients and the controls. It is suggested, that the infected individual is not able to increase his resistance via the more effective functioning of the non-specific line, which in effect promotes the possibly multiple occurrence of the disease.

Adult↗
PubMed1989

[Indicators of nonspecific resistance of the body in patients with erysipelas].

A study is presented of indices of unspecific resistance of the body in 63 patients with erysipelas during the acute period of the disease and during recovery. In the acute period of the disease all patients revealed depending on the degree of endogenous intoxication: reduction of the content of fibronectin in the blood, significant reduction of the resistance of erythrocytes--increase of the per cent of peroxidation hemolysis, increase of the content of malonic dialdehyde--an index of disorders of lipid peroxidation, increased content middlemolecular peptides, circulating immune complexes and products of fibrin-fibrinogen degradation. The authors substantiate the expediency of using sodium thiosulfate possessing detoxicating, antiinflammatory and antiallergic antioxidant properties and the capacity to bind circulating immune complexes.

Adolescent↗
PubMed1988

[Effect of a streptococcal allergen on the rosette-forming capacity of the T-lymphocytes in erysipelas patients].

The reaction of antigen-dependent E-rosette formation with the hemolytic streptococcal antigen in erysipelas patients is indicative of the ambiguous role of the specific immunological transformation of the body in respect of the infective agent antigens in different clinical forms of the disease and is of prognostic importance as regards the chronic transformation of the infectious process and the development of the relapses of the disease.

Adolescent↗
PubMed1986

[Acid-base status and antibody production in pigs immunized with a vaccine against erysipelas].

Studied was the correlation between the acid-alkaline status and the antibody production in pigs treated with the VR-2 vaccine against swine erysipelas. A progressive growth of the values of the B-system indices was established as early as the 24th hour in correlation with the higher HCO3 and CO2 values. The latter substantiated a new profile of the acid-alkaline state, which persisted up to the 10th day. The subsidiary increase in the concentration of HCO3 from the 10th to the 15th day as well as of pCO2 on the 15th day was associated with the highest percent and absolute number of B lymphocytes and 'AOK' at 10(6). This confirmed the presence of a gradual correlation between the indices of the acid-alkaline state and the B system.

Acid-Base Equilibrium↗
PubMed1987

[The effect of a sodium nucleinate and levamisole combination on the effectiveness of antibiotic therapy and bicillin prophylaxis of erysipelas recurrences].

Two hundred and two patients with acute erysipelas and 28 patients in remission of the disease were examined. 102 patients of the main group were treated with sodium nucleinate and levamisole in addition to the routine therapy and 100 patients of the control group were subjected to the routine therapy alone. The favourable effect of the immunomodulators on the clinical picture of the disease and the immune status of the patients was shown.

Adult↗
PubMed1979

[Prostaglandins in skin blisters of bullous erysipelas, dermatitis herpetiformis and herpes gestationis (author's transl)].

The PGE2 and PGF2 alpha content of bullae developing spontaneously on the skin was investigated by radioimmunoassay in 12 patients with different skin diseases. The PGF2 alpha level was also established in the plasma and urine. In herpes gestationis, dermatitis herpetiformis and bullous erysipelas the PGE2 and PGF2 alpha content of the bullae considerably exceeded the plasma and urinary PG levels. The findings were thought to be in relation with the acute inflammation of the skin, the mechanism of bulla formation as well as with pruritus.

Adult↗
PubMedDate not supplied

An outbreak of erysipelas in chukars.

A peracute severe outbreak of erysipelas in chukars (Alectoris chukar) caused 55% mortality. Pheasants and quails on the same premises were not affected. Possible sources of infection and pathogenesis are discussed.

Animals↗
PubMed1979

Necrotizing erysipelas of the eyelids.

A 72-year-old, healthy white woman presented with rapidly advancing necrotizing erysipelas of the upper and lower eyelids. There was no previous history of trauma or skin abrasions. The patient was treated with intravenous methicillin (Staphcillin) for 2 weeks and oral cloxacillin (Tegopen), for 1 week with intensive wound cleaning and debridement. After 3 months of continuous wound care, the patient has healed her wounds by second intention, with a moderate amount of lid contracture. Further surgical correction of the lower lid defect may be necessary.

Aged↗
PubMed1979

Bilateral pleural effusions associated with generalized primary lymphoedema and erysipelas. A case report and the probable pathogenesis.

A case of bilateral pleural effusion in association with generalized primary lymphoedema and erysipelas, but without yellow dystrophic nails, is reported and the probable pathogenesis of the condition discussed. It is known that the primary defect lies in decreased lymphatic drainage. However, the consequent intravascular hypovolaemia and secondary hyperaldosteronism have not previously been demonstrated.

Adult↗
PubMed1980

An improved quantitative method for the study of fibrinolysis in the skin as exemplified in patients with leukocytoclastic vasculitis and erysipelas.

The activity of plasminogen activator has been measured in tissue sections with the aid of a modified Todd technique. Frozen skin biopsies were sectioned and the tissue covered with fibrin-plasminogen film. After incubation at 37 degrees C fibrinolysis was studied for a period of 30 min and was graded into six exponentially increasing steps. During this period, grades were linear with the llogarithm of time of incubation. The rate of fibrinolysis is a measure of the activity of the plasminogen activator and is expressed by the slope of the linear regression of grades versus the ogarithm of time; the value of the slope is proportional to the common logarithm of the activity of the plasminogen activator present in the section. Using urokinase as a specific plasminogen activator, the same linear expression was shown with time, indicating the validity of our grading and experimental system. Eleven healthy subjects served as controls to 6 patients with leukocytoclastic vasculitis and 4 patients with erysipelas and 4 with necrotizing fascilitis. The controls showed values similar to the non-involved skin in the patients. The activity was higher in the arm than in the thigh sites. The activity in the thighs was lower in women than in men. A decrease in the plasminogen activator activity was found in the three disorders.

Adult↗