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[Diagnostic value of chest x-ray film in recognizing complications following homologous lung transplantation in the dog].

The postoperative controls of the course after unilateral homologous lung transplantation were interpreted by chest X-ray films of 86 dogs. Radiomorphologic findings in the transplanted lung had developed 69% of the surviving animals in the end of the 5th and 80% on the 9th postoperative day. The descriptive phenomena of the chest X-ray films were compared with the post-mortem findings concerning their etiology. Phenomena caused by rejection, by operation, and in a third group by rejection and operation could be separated statistically as to the temporal occurrence. - In that manner the partial or total shadow of the graft is a sign of rejection after the 5th postoperative day and the pneumothorax is a sign for a postoperative complication before the 5th day, on the other hand a phenomenon for the rejection after this time. - The radiologic findings are restricted by imperfect position of the animals during the radiograph and by overshadowing bony parts of the thorax. The diagnostic value of the chest X-ray film is reduced much, because the differential diagnosis to the radiomorphologic findings requires additional diagnostic methods for instance scintiscanning, angiography, bronchospirometry, and biopsy.

Animals↗

[Lung functions after single-lung homotransplantation in dogs (author's transl)].

Unilateral homotransplantation of the lung was performed in ten healthy mongrel dogs. Assessment of pulmonary function was obtained immediately after transplantation ten days and four weeks postoperatively. A conventional endotracheal tube was used for measurement of total lung function. A special tube was deviced for bronchospirometric measurements in dogs. A moderate increase of tidal volume and marked increase of respiratory rate and minute ventilation could be noted immediately after transplantation. Oxygen consumption was not changed significantly. There was a marked decrease in arterial pO2-level following transplantation, which was improved during the follow-up studies and found within normal limits at the tenth postoperative day. Bronchospirometry immediately following transplantation revealed equal ventilation values of both lungs, but oxygen consumption of the transplant was reduced 50% compared to the recipient's own lung. On the tenth postoperative day ventilatory function of the transplant was found close to that of the recipients own lung. Oxygen consumption in respiratory equivalent at this time averaged two thirds of the animal's own lung. Four weeks following transplantation no further significant change of respiratory function could be noted.

Animals↗

[Clinical study on patients with lateral position test (LPT) for determining the relative function on each lung].

Comparing the lateral position test (LPT) on 20 patients of lung cancer with bronchospirometry of tracheal intubation, the authors found that the VC, oxygen uptake were in high positive correlation, while VE were in moderate positive correlation. Therefore, they conclude that LPT could substitute the complicated tracheal intubation for determining the relative function of each lung before the total pneumonectomy.

Carcinoma, Bronchogenic↗