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PubMed1987

Enteric-coated aspirin bezoar: elevation of serum salicylate level by barium study. Case report and review of medical management.

The gastric accumulation of enteric-coated aspirin tablets due to peptic ulcer disease or gastric outlet scarring and the impaired gastric emptying that results have been previously reported. In the case reported herein, an unanticipated peaking of plasma salicylate levels occurred following radiographic studies in which barium was used. This phenomenon prompted an in vitro study in which dissolution rates of enteric-coated aspirin in various barium preparations were determined, suggesting that dissolution is dependent upon effervescent activity of the milieu, as well as pH. The use of barium in diagnosing suspected accumulation of enteric-coated aspirin is discussed, and techniques for tablet removal are reviewed.

Aged↗
PubMed1981

Bezoars, stones, thrombi, thrombophlebitis, emboli, vascular disorders, paralytic ileus, intercellular extravascular glue and dessication: fundamental physical factors in the formation of concretions.

Usually blood does not stagnate nor clot in its vessels. Spasm in a vein or artery, constricting the wall or sphincter, seines and assembles the ingredients of a thrombus. It further leads to rupture of the vessel's wall, so extravascular glue can complete or augment the recipe. The mechanisms of blood clotting, include three prime factors, stasis, dessication and extravascular glue. Idiopathic disorders of the arteries and veins and similar to each other and to those in other systems and, e.g. analogous to paralytic ileus and intestinal obstruction. Dissecting, i.e. intralaminar hemorrhage in the pathogenesis of emboli, venous/arterial and vascular occlusion, merits more attention as do the sphincters and valves of the vascular system.

Bezoars↗