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Effect of five daily intravenous treatments with oxytetracycline hydrochloride on the carrier status of bovine anaplasmosis.

Intravenous administration of oxytetracycline hydrochloride at the rate of 22 mg/kg daily for 5 days was effective in rendering parasite-free 11 adult cattle that were naturally infected Anaplasma marginale carriers. The treatment did not cause any noticeable distress or side effect. Through 12 posttreatment months, the efficacy of the treatment procedure was evaluated by serologic tests and subinoculation of blood into susceptible splenectomized calves. Results of the rapid card agglutination test were positive for 5 cattle at 2 months after treatment, but negative for all cattle at 4 through 12 months. Complement-fixation titers were variable and transient in posttreatment serologic studies. After subinoculation of blood into splenectomized calves (at 4 and 12 months after chemotherapy), serologic, hematologic, or clinical evidence of infection with A marginale was not seen during a 60-day observation period.

Anaplasmosis↗

Occurrence of concurrent trypanosomosis, theileriosis, anaplasmosis and helminthosis in Friesian, Zebu and Sahiwal cattle in Uganda.

An epidemiological investigation was conducted on farms in Tororo and Soroti districts of Uganda from January to February 2000 to determine the cause of reported persistent mortality of cattle. Blood and faecal material of 98 cattle comprising of 33 Friesians, 58 Zebu and 7 Sahiwal were examined. Results revealed that seven (7.1 %) cattle had trypanosome infection, mainly due to Trypanosoma vivax and T. brucei, 17 (17.3%) Fasciola infection, 28 (28.6%) gastrointestinal nematode infection, 33 (33.7%) Theileria sp. infection and 13 (13.3%) Anaplasma marginale infection. Mixed infections were detected in 30%, 20.6% and 43 % of the Friesian, Zebu and Sahiwal cattle respectively. Anaemia (PCV < 25) was detected in 24%, 19% and 14% of the Friesian, Zebu and Sahiwal cattle respectively. Persistent mortality of cattle on these farms could have been due to either single or mixed parasitic infections probably exacerbated by malnutrition.

Anaplasmosis↗