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At least 235 records · Page 13Linked to original sources

A retrospective analysis of primary eye cancer at the University of Alabama at Birmingham 1958-1988. Part I: Eye and orbital cancer.

Records of 99 patients with 100 primary eye cancers seen at the University of Alabama Hospital for the years 1958-1988 were reviewed. Three ocular cancers were found to predominate: 1) choroidal melanoma, 2) retinoblastoma, and 3) squamous cell carcinoma. Epidemiologic distribution of the population is presented and compared to that of tumors commonly seen in general ophthalmic practice.

Adolescent↗

A retrospective analysis of primary eye cancer at the University of Alabama 1958-1988. Part 2: Eyelid tumors.

Records of 117 patients with eyelid tumors on file at the University of Alabama at Birmingham were reviewed. Basal cell carcinoma was the single most common tumor, followed by squamous cell carcinoma, cutaneous melanoma, meibomian gland carcinoma and sebaceous gland carcinoma. A high percentage of patients with eyelid tumors were found to have secondary skin and non-skin tumors (41 percent).

Adult↗

Medical malpractice and access to obstetrical care in Alabama.

The medical malpractice insurance crisis of the mid-1980s has abated, but nonetheless there are concerns that the threat of liability continues to have a deleterious effect on access to obstetrical services for low income women. Currently, at the national level there is discussion over whether the tort system should be replaced with a no fault compensation scheme similar to the worker's compensation system. Florida and Virginia have already enacted no fault compensation schemes for certain birthrelated neurological injuries. After reviewing the situation in Alabama with respect to claim frequency and severity, insurance costs and access to obstetrical care, we will examine proposals for a fundamental restructuring of the medical liability system.

Alabama↗

Prevalence and isolation of Toxoplasma gondii from white-tailed deer in Alabama.

Nineteen white-tailed deer (Odocoileus virginianus) from 5 counties in Alabama were examined for infection with Toxoplasma gondii. Twenty-gram samples of heart tissue were bioassayed in mice, serum was examined for T. gondii antibodies using the direct agglutination test, and sections of heart muscle were examined histologically for tissue cysts. Toxoplasma gondii was isolated from 4 of 19 (21%) white-tailed deer hearts. Antibody titers of greater than or equal to 1:50 were found in sera from 7 of 16 (44%) white-tailed deer. Histological examinations of tissue sections from white-tailed deer hearts were negative for T. gondii.

Agglutination Tests↗

The Alabama automated defibrillation pilot program.

The Alabama Chapter of the American College of Emergency Physicians is now sponsoring a pilot program using EMT-Basic equipped with semi-automatic ("smart") defibrillators for the treatment of cardiac arrest patients in the field. This article outlines the rationale for the program along with present status of results.

Alabama↗

The isolation of spiroplasmas from mosquitoes in Macon County, Alabama.

During the summer months of 1985, 1,298 adult mosquitoes comprising 21 species and 7 genera were collected in Macon County, Alabama. Mosquitoes were collected from four sections of the county with CO2-baited light traps. Spiroplasma cultures were isolated from two pools of 24 and 25 Aedes fulvus pallens, one pool of 22 Anopheles punctipennis and one pool of 7 Culex nigripalpus. Electron microscopic studies of the isolates revealed helical, wall-less cells.

Alabama↗

Potential vectors of bluetongue and epizootic hemorrhagic disease viruses of cattle and white-tailed deer in Alabama.

Fourteen Culicoides spp. were collected on Holstein cattle in Alabama: C. arboricola, C. bickleyi, C. biguttatus, C. debilipalpis, C. guttipennis, C. haematopotus, C. obsoletus, C. paraensis, C. piliferus, C. sanguisuga, C. spinosus, C. stellifer, C. variipennis and C. venustus. Six Culicoides spp. were collected directly from white-tailed deer (Odocoileus virginianus): C. debilipalpis, C. niger, C. obsoletus, C. paraensis, C. sanguisuga and C. stellifer. Based on their host-feeding behavior, abundance and seasonal occurrence, the following 4 species warrant particular attention as potential vectors of bluetongue (BT) and epizootic hemorrhagic disease (EHD) viruses in the southeastern US: C. debilipalpis, C. obsoletus, C. paraensis and C. stellifer.

Alabama↗

Comments from the University of South Alabama Burn Center.

The above discussion summarizes our current treatment protocols at the University of South Alabama Burn Center. These are always undergoing evaluation and change. There are many materials currently available for treating the burn wound and even more new ones on the horizon. The efficacy of these materials is often unit dependent, and because of specific unit microbial flora may produce wonderful results at one center and poor results at another. Constant review of outcome is mandatory. The ideal skin substitute for all wounds and all clinical situations does not exist. The clinician must be thoroughly familiar with the properties of many products and be prepared to change from one material to another as the clinical situation dictates.

Alabama↗

The Alabama Perinatal Outcome Project: some methodological issues.

As practice networks are built to facilitate the study of unselected patient populations, special advantages and problems of these systems are emerging. The Alabama Perinatal Outcome Project is an example of such a network which has been functioning for over three years. Key methodological questions of sample selection, completeness and reliability of data, and research definitions have been addressed in the initial phase of the project. The evolution of an approach to these methodological issues and some preliminary data are presented for consideration by those designing practice networks.

Adult↗

Postneonatal mortality among normal birth weight infants in Alabama, 1980 to 1983.

To identify reasons for the racial differential in postneonatal deaths and possible intervention strategies, Alabama's linked birth-death file was used to evaluate causes of postneonatal mortality for the 1980 to 1983 cohorts of normal birth weight infants. Causes were aggregated into six categories, and cause-specific rates were compared by race and by urban-rural residence. Both total and cause-specific postneonatal mortality rates among black infants were two or more times higher than for white infants, except for congenital anomalies. The greatest differential was for infection-related deaths. Rural residence increased both the risk of postneonatal death and the magnitude of the racial differential. The risks were especially elevated for deaths due to infection and "systemic causes" (including those in the perinatal category). Only 26% of postneonatal deaths were probably not preventable, and nearly one third were clearly preventable. Potential prevention strategies include injury control, prevention of infectious diseases, and prompt treatment of infectious diseases.

Alabama↗

Fungus species isolated from commercial hatcheries in Alabama.

Selected locations (incubators, incubator rooms, hatchers, hatcher rooms, chick pools, and egg rooms) in six commercial broiler hatcheries in Alabama were sampled for fungus species over a 12-month period (May 1977-April 1978) by open-plate techniques (cornmeal agar or Sabouraud's dextrose agar). Colonies at each location were counted at 24, 48, and 72-120 hours postexposure. Thirty-five species representing 21 genera were identified. The most prevalent genera were Cladosporium, Penicillium, Aspergillus, Geotrichum, and Fusarium. Aspergillus fumigatus was associated with clinical disease in the baby chick on several occasions, and Cladosporium cladosporioides was the most prevalent species isolated. In general, isolations increased in early spring and summer.

Alabama↗

Survey of leptospiral agglutinins in the sera of swine of southeastern Alabama.

The occurrence of leptospirosis in swine of southeastern Alabama was determined. A total of 627 sera were tested, using the microscopic agglutination method, with live antigens of 12 serovars. Of the sera tested, 121 (19.3%) had a titer of 1:100 or greater to the serovars employed. The percentage distribution of sera with titers of greater than or equal to 1:100 among serovars most commonly reported was as follows: Leptospira interrogans serovars pomona, 3.8%; icterohaemorrhagiae, 3.3%; canicola, 1.6%; hardjo, 0.7%; and grippotyphosa, 0.16%. Of the less commonly recognized leptospiral serovars, the percentages reacting were as follows: ballum, 4.9%; autumnalis, 3.2%; pyrogenes, 1.1%; and bataviae, 0.4%. None of the sera reacted with antigen of serovars australis, tarassovi, or wolffi.

Agglutinins↗

Serological studies on leptospirosis in cattle in east central Alabama.

Serological surveys of leptospiral antibodies in cattle were carried out in Macon and the surrounding counties of East Central Alabama. A total of 286 bovine serum samples were screened for the presence of antibodies against live antigens from twelve pathogenic leptospiral serotypes using a microscopic agglutination test. The most frequently encountered serotypes were Leptospira hardjo (47%), Leptospira wolffi (34%), Leptospira canicola (12%), Leptospira pomona (10%) and Leptospira ballum (10%). Leptospira autumnalis, Leptospira grippotyphosa, Leptospira icterohemorrhagiae, Leptospira pyrogenes and Leptospira tarassovi were observed in less than 5% of the samples.

Alabama↗

Potential vectors of Dirofilaria immitis in Macon County, Alabama.

A study was conducted in Macon County, Alabama (east-central) during the mosquito breeding seasons of 1978 and 1979 to determine the potential vector(s) of Dirofilaria immitis. Live mosquitoes were collected with CO2-baited, miniature light traps, and small hand aspirators. These mosquitoes were subsequently dissected to determine whether immature stages of the heartworm were present. Specific communities were selected based on their having at least 4 known cases of D immitis infection present in the local dog population. All positive collections were made between the months of May and September. Of 326 Anopheles punctipennis females dissected, 34 were positive, and of 84 Aedes vexans 6 were positive for infective (L3) larvae. Of 520 Culex quinquefasciatus females tested, 14 contained 2nd-stage larvae only. Immature stages of D immitis were collected during most of the mosquito breeding season. Data collected during the survey indicate that An punctipennis and to a lesser extent, Ae vexans are probably the principal vectors of D immitis in Macon County, Ala.

Alabama↗

A seroepidemiologic survey of antibody to bluetongue virus in Alabama cattle.

Bluetongue (BT) is an insect transmitted viral disease of sheep that often causes mild or inapparent disease but rarely causes severe disease in cattle. Until recently, bluetongue viral infection was believed to be more prevalent in the Western United States, as compared with other regions of the country. However, a national survey for bluetongue antibody and clinical evidence of the disease in the Southeastern United States prompted the present investigation that was designed to determine the serological prevalence of BT virus in Alabama cattle. Results of the study demonstrated that 16% of the samples collected from 1,500 cattle in 64 of the 67 counties were positive. The prevalence of positive cattle in the western part of the State was significantly higher (P less than .001) than the prevalence in the eastern half of the State. On a herd basis, 52% of all herds tested had positive animals. Results of this study suggest that bluetongue infection is more common in the Southeastern United States than previously suspected.

Alabama↗

Neonatal deaths in Alabama. III. Out-of-hospital births, 1940-1980.

Out-of-hospital births in Alabama are characterized with special emphasis on the period from 1970 to 1980. Women having an out-of-hospital birth were more likely to be nonwhite, aged greater than or equal to 35, and multiparous and to have little or no prenatal care. However, within the group of women having out-of-hospital delivery, characteristics which predicted neonatal death included being white, aged less than 20, primiparous, and unmarried and having little or no prenatal care. Both the risk factors for and outcomes of out-of-hospital birth differed markedly by race. In all, out-of-hospital births, which declined from 25% to 0.5% of all births from 1940 to 1980, were associated with a twofold increase in neonatal mortality. The major care provider for out-of-hospital births, the "granny" midwife, was found to have little knowledge about, or ability to provide, modern obstetric care. High-risk status of the patients, limited capability of the care-givers, and lack of appropriate medical resources are suggested as the likely reasons for the excess neonatal mortality in out-of-hospital births.

Adult↗

Increase of HLA-DR4 in melanoma patients from Alabama.

This report describes the association of HLA-DR phenotypes in a population of 91 Caucasian melanoma patients compared with 106 Caucasian controls from the Sunbelt region of the United States. Over 75% of both patients and controls were born in Alabama or a surrounding state. There was a significant increase in the frequency of HLA-DR4 (chi 2 = 12.8; rho = 0.0003). This was present in 38.5% of the patients compared to a 16.0% frequency in the controls, producing a relative risk of 3.3. The difference in DR4 distribution remained significant after correcting for the number of antigens (rho c = 0.0018). The patients were then grouped into two categories, "low risk" and "high risk," based on their clinically assessed risk at presentation for metastatic involvement. The decrease of DR3 in the high-risk group (chi 2 = 5.2; rho = 0.02) suggested that it may represent a marker for long-term survival. Thus, it appears that susceptibility to developing melanoma may be associated with DR4 while survival may be associated with DR3.

Alabama↗