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Results for “17-Hydroxycorticosteroids”

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At least 235 records · Page 13Linked to original sources
PubMed1979

[Changes in the progress of infectious diseases caused by changes of natural resistance and of the steroid metabolism (author's transl)].

It is demonstrated that it is possible to change the stereotyped reaction of the steroid metabolism to infection by means of external influences. The progress of infectious diseases can be detoriated and the average duration of life can be shortened by rearing a special strain of test rabbits or by lack of protein in the diet, by blocking the RES, by cortisol, estradiol and thyroxin, by glucose and by polyvinylpyridin-N-oxid. - The time of survival is prolonged by testosterone, dehydroepiandrosterone and cyproterone, also by cystein, aristolochia acid and treatment with pyrifer. - No effect whatever on the progress of an infectious disease is produced by the vitamines A, B1, B6, D, E and especially ascorbinic acid, also an extract of thymus gland, spleen, insulin, a preparation with STH, and Norgestrel, DMSO and treatment with B, bifidum and with omnadin.

17-Hydroxycorticosteroids↗
PubMed1979

[Hormone and mediator content in the blood of the adrenals and in the peripheral blood in hypertension].

The concentration of the fractions of corticosteroids, aldosterone, catecholamines, and cyclic nucleotides (cAMP and cGMP) in blood of the adrenal veins and the activity of renin in blood of the renal veins were studied in 22 patients with stages IIA and IIB hypertensive disease. At the same time the content of these substances in the peripheral blood was determined and compared with the level of steroid and catecholamine excretion in the daily urine. An increase in the content of free 11 OCS and F fractions in the peripheral blood and blood of the adrenal veins was revealed in all patients examined.

11-Hydroxycorticosteroids↗
PubMed1979

Antepartum pituitary infarction.

Antepartum pituitary infarction occurs only in insulin-dependent diabetic patients. It is manifested by severe headache, followed by decreasing insulin requirements. Delivery is frequently premature, with high fetal wastage and increased maternal mortality. During the puerperium, the first manifestation of pituitary deficiency, other than a lower insulin requirement than would be expected, is failure to lactate. Subsequent evaluation of pituitary function reveals variable deficiencies with loss of growth hormone and gonadotropins being most frequent. This case is the eighth report of this entity, and it represents the first patient to survive a pituitary infarction prior to the third trimester of pregnancy. Recognition of this syndrome is critical in order to ensure that the mother's health and the viability of the offspring be preserved.

17-Hydroxycorticosteroids↗
PubMedDate not supplied

[Effect of physical exertion on the adrenal gland function and cardiovascular system in diabetes mellitus].

The response of the adrenal glands and the cardiovascular system to dosaged cycloergometric exercises was studied in 35 young patients with diabetes, depending on the state of carbohydrate metabolism, in comparison with control healthy individuals. In diabetic patients physical load proved to induce an insignificant activation of the adrenal glucocorticoid function with a marked response of the sympathicoadrenal system. Physical exercises permitted to detect reduction of myocardial reserves and disturbance of vascular reactivity in the majority of diabetic patients. The detected changes in the adrenal gland response could serve as one of the causes of inadequate response of the cardiovascular system to physical load, and of reduced tolerance to it in diabetic patients.

17-Hydroxycorticosteroids↗
PubMed1979

[Endocrinologic and ophthalmologic findings before and after transnasal surgery in so-called chromophobe pituitary adenomas].

Pre- and postoperative visual and endocrine functions were examined in 54 patients with so-called chromophobe pituitary adenomas operated on by the transnasal approach. The preoperative examination showed visual disturbances in 41 of 48 patients. A loss of gonadal function was present in 93% of the women and 69% of the men. Impairment of adrenal function was found in 37% and of thyroid function in 18% of patients. Hyperprolactinemia was present in 16 of 29 patients examined. The visual findings remained unchanged, normal or improved in 75% of patients. Impairment occurred in 3%. Eight patients experienced improvement of gonadal function and 3 of adrenal function, whereas no postoperative improvement of the thyroid function was observed. Deterioration of gonadal function occurred in 4, of adrenal function in 7, and of thyroid function in 9 patients. Hyperprolactinemia was reduced in all cases.

17-Hydroxycorticosteroids↗
PubMed1979

Improved radioimmunoassay for 11-deoxycortisol (compound S) in plasma.

We describe a radioimmunoassay for 11-deoxycortisol (Compound S) that involves preliminary chromatography on Sephadex LH-20, to isolate 11-deoxycortisol from crossreacting structurally related steroids. Pools with means of 3.4, 12.9, and 69.9 micrograms/L gave intra-assay coefficients of variation of 9.7, 9.6, and 11.4%, respectively; pools with means of 4.6, 27, and 95 micrograms/L gave inter-assay CV's of 10.1, 9.7, and 6.2%, respectively. A normal range (mean +/- 2SD) of 0.5 to 12.0 micrograms/L was obtained. This procedure is useful for the specific determination of 11-deoxycortisol, commonly determined in blood as part of the metyrapone test for assessing pituitary corticotropin reserve.

17-Hydroxycorticosteroids↗
PubMed1979

[Dynamics of several indices of the enzyme-hormone status of the body after hypobaria and during decompression sickness].

Hormone content and enzyme activity change under the influence of hyperbaria and in decompression disease long before the symptoms of the disease appear. Apart from that, an increase in adrenalin, noradrenalin, 17-oxycorticosteroids, and glucose concentrations, erythrocyte number and hemoglobin, as well as lowering of amylase and catalase activities are the indicative signs for prognostication and diagnosis of the decompression disease.

17-Hydroxycorticosteroids↗
PubMedDate not supplied

[Dietary prevention of certain changes in the human body in the presence of neuro-emotional stress].

Simulated stress conditions (rise to a simulated altitude of 8000 m, anticipation of an exposure to acceleration, mental work to be done under the conditions of time deficiency, "success" or "failure") brought about changes in the protein, carbohydrate, vitamin metabolism, heart rate, adrenal function, and peripheral blood. Nutrient ingredients (vitamins, glucose, minerals, phosphatid concentrate) added to the diet before and during stressful exposures were shown to correct the parameters studied.

17-Hydroxycorticosteroids↗