Clinical significance of fetal heart rate patterns during labor. IV. Agonal patterns.
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Activity of the paraspinals, abdominals, and hip extensor muscles, heart rate, and skin conductance were measured in 13 chronic low back pain patients (CLBP) and 13 controls during static postures and psychological stress. After 10 min of baseline-rest, a subject was tested during standing, 45 degrees bend, maximum bend, posterior and anterior pelvic tilts, sitting, and supine with knees up, followed by mental arithmetic and the cold pressor. The postures were grouped into supported, balanced, and unbalanced categories. Multivariate analyses of variance revealed differences due to posture categories, but not due to group membership. It was concluded that while work is needed to understand normal muscle function during common movements, there is no compelling evidence that back muscle functioning in CLBP patients differs significantly from control subjects.
The histochemical distribution of 14 enzymes in the human amnion at term are described. Adenosine triphosphatase, 5'-nucleotidase, acid phosphatase and nonspecific esterase show continuous gradations of enzyme activity. Cells with intense activity are prominent in acid phosphatase and nonspecific esterase preparations. A distinct subpopulation of amniotic cells can be defined by their alkaline phosphatase activity. The possible correlations with morphological studies are discussed.
Evaluation of fetal movements revealed a striking difference of motor activity during assumed quiet sleep and active sleep in the fetus. Furthermore, motor activity was found to be enhanced in post-term fetuses. Consequences for the methods of fetal acceleration determination (FAD) and daily fetal movement count (DFMC) are discussed.
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The symptom scores on the Schedule for Affective Disorders and Schizophrenia (SADS) of 21 unipolar and 12 bipolar depressive patients diagnosed with Research Diagnostic Criteria (RDC) were correlated with the monoamine metabolites homovanillic acid (HVA), 3-methoxy-4-hydroxyphenylglycol (MHPG), and 5-hydroxyindoleacetic acid (5HIAA) in the cerebrospinal fluid (CSF). For the unipolar group, multiple regression analyses revealed strong multiple correlations (from r = 0.92 to 0.97) to the effect that high- and low-HVA, high- and low-MHPG, and high- and low-5HIAA syndromes, respectively, could be isolated. The bipolars were too few for the same analyses to work well, but there is evidence for the high- and low-monoamine syndromes to be characterized by differential symptomatology in bipolar and unipolar patients. Through the comparison of monoamine metabolite values predicted from a total of 18 SADS symptom items with the true CSF values, a computer program was able to classify 20 of the 21 unipolar and all the 12 bipolars correctly. The results are consistent with a hypothesis of the pathoplastic role of individually set (genetically determined?) brain monoamine homeostases in shaping the profile of an affective episode.
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