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PubMed1985

Penile thrombophlebitis as a presenting manifestation of pancreatic carcinoma.

Peyronie's disease of the penis is a condition in which there are plaques of fibrous tissue surrounding the corpus cavernosum causing deformity and painful erection. We describe a patient with pancreatic carcinoma who presented with Peyronie-like features. This pseudo-Peyronie's disease was actually an unusual superficial thrombophlebitis of the dorsal penile vein. The literature regarding neoplasm-associated thrombophlebitis is reviewed.

Adenocarcinoma↗
PubMed1979

Popliteal cyst mimicking thrombophlebitis as the first indication of knee disease.

Five patients, none of whom were previously known to have knee disease, developed leg swelling which was misdiagnosed as thrombophlebitis. Four were treated with anticoagulants and one developed a large calf hematoma requiring fasciotomy. The primary physicians failed to appreciate evidence of knee disease in these patients, although the rheumatology consultant found knee effusion, and a popliteal cyst was found by arthrography or ultrasonography in every case. The occurrence of popliteal cyst as the first sign of knee disease emphasizes the importance of careful examination of the knee in all patients with a clinical picture of thrombophlebitis.

Adult↗
PubMed1979

Rupture of a non-rheumatoid popliteal cyst: a syndrome mimicking thrombophlebitis.

Rupture of a popliteal cyst and dissection of its contents into the calf may produce pain, swelling, a positive Homan's sign and other findings closely resembling thrombophlebitis of the calf. The correct diagnosis is not often made, and the patient is subjected to needless long term anticoagulant therapy with its potential complications. To avoid this, it is essential that this possibility be kept in mind in all patients in whom the diagnosis of thrombophlebitis is considered. The history of preexisting arthritis of the knee, joint effusion and popliteal cyst are strongly suggestive of a ruptured popliteal cyst. This diagnosis can be verified by arthrography, ultrasonography, computed tomography and radionuclide scanning. Arthrography is preferred because it reveals superior anatomic detail thereby making differentiation between an encapsulated calf cyst, with smooth walls, and rupture, with irregular feathery margins, possible. Three illustrative cases are presented and the literature is reviewed.

Adult↗
PubMed1983

Pelvic vein thrombophlebitis: diagnostic dilemma and therapeutic challenge.

Pelvic vein thrombophlebitis is an unusual, but extremely serious, complication of pelvic surgery. It occurs in approximately 0.5 to 1 per cent of patients who develop operative site infections. It may present as two distinct clinical syndromes: acute ovarian vein thrombosis and diffuse thrombosis of multiple small pelvic vessels. Accurate diagnosis is hampered by the absence of a reliable, specific, and noninvasive test for the disorder. Treatment of pelvic vein thrombophlebitis requires administration of broad spectrum antibiotics, intravenous heparin, and, in selected cases, ovarian vein and vena cava ligation.

Anticoagulants↗
PubMed1984

Dihydroergotamine in prevention of infusion thrombophlebitis. A randomized trial.

The efficiency of subcutaneous dihydroergotamine in preventing infusion thrombophlebitis was assessed in a randomized trial. One hundred and fourteen postoperative patients were studied. They furnished a total of 160 infusion sites. The difference between treatment and control group with regard to incidence of infusion thrombophlebitis was not significant (p greater than 0.05). Accordingly dihydroergotamine has no substantial effect.

Clinical Trials as Topic↗
PubMed1984

Deep venous thrombophlebitis associated with lithium toxicity.

The development of deep venous thrombophlebitis in a lithium-intoxicated patient is described. The sedation, lassitude, and decreased activity of the toxic state are proposed as risk factors for the development of hemostasis and thrombophlebitis. The need for greater awareness of this possible complication in patients who are lithium toxic is advanced.

Female↗
PubMed1984

[Relation between the development of thrombophlebitis of the subclavian vein and the side of catheterization].

Under study was the development of thrombophlebitis of the subclavian vein after its catheterization in 2435 patients. The complication was shown to appear in 1,5% of all the manipulations. Thrombophlebitis of the right subclavian vein was found to develop four times more often than that of the left one. It is accounted for by differences in the anatomical structure of the right and left subclavian veins.

Adolescent↗
PubMed1984

Septic pelvic thrombophlebitis as an enigmatic cause of persistent puerperal fever course of disease diagnosis and treatment.

A rare case of septic puerperal pelvic thrombophlebitis is presented. This condition is an uncommon but potentially serious complication of pyogenic pelvic infection. The purpose of this report is to describe a particular form of septic pelvic thrombophlebitis (SPT) that frequently eludes diagnosis because of the absence of positive abdominal or pelvic findings. Our recent experience with this entity is interesting, because of the striking effect of heparin after many days of unsuccessful high dose multiple antibiotic treatment.

Adult↗
PubMed1983

Septic pelvic thrombophlebitis: an update.

Septic pelvic thrombophlebitis is the result of serious pelvic infection usually following obstetric or gynecologic procedures. The management of this condition is of historical interest to the department of obstetrics and gynecology at Tulane, and therefore a retrospective case evaluation and a prospective surveillance were undertaken. This study indicates that septic pelvic thrombophlebitis is seen very rarely today. Possible reasons for the decline in the incidence of this problem and a management plan are presented. Three cases are included.

Adult↗
PubMed1978

Thrombophlebitis in systemic lupus erythematosus.

Thrombophlebitis occurred in 14 (12.2%) of 114 patients with active systemic lupus erythematosus (SLE). Abnormal clotting occurred despite the presence of thrombocytopenia or circulating anticoagulants in some of the patients, and the development of pulmonary emboli was verified in seven. Although infrequently reported, the association of thrombophlebitis with active SLE is apparently not uncommon. While there were no features that distinguished this group of patients from other groups of patients with SLE, there are some possible mechanisms. Recognition of this complication of SLE is important because of the frequent occurrence of SLE-induced pleuritis and its similarity to the pain of pulmonary emboli.

Adolescent↗
PubMedDate not supplied

Incidence of thrombophlebitis in humans with the diazepam vehicle.

Forty-one adult males volunteered for a study designed to investigate the thrombogenicity of the Valium® vehicle. Utilizing a standardized protocol, each subject received a sedative dose of Injectable Valium® in the antecubital fossa of one arm and an equivalent volume of vehicle in the contralateral arm. Both were administered with a continuous infusion drip of 5 per cent dextrose in water. Post-operative evaluation extended over 10 weeks and included clinical observation and palpation. Ultrasonic tests for occluded or impaired blood flow were performed with a Doppler Flowmeter.Five subjects (12.2 percent) had venous sequelae with the Valium® and two (4.8 percent) developed sequelae with the vehicle. The incidence of venous sequelae reported in the present study was considerably lower than in previous investigations (66.6 per cent and 37.5 per cent) utilizing the same protocol. The present study indicates that time of continuous infusion appears to contribute to thrombophlebitis subsequent to intravenous injection of Valium®. It also appears that the diazepam vehicle is not the major factor in the occurrence of thrombophlebitis.

Adult↗
PubMed1982

Superficial thrombophlebitis of lower limbs.

In the absence of malignancy, thrombophlebitis of the lower limb is invariably associated with pre-existent varicose veins. Not until pulmonary embolism was reported to occur in superficial phlebitis did the clinician introduce anticoagulants and/or surgery in the management of this condition. In an effort to reach an effective approach to this problem, 1,000 consecutive cases of varicose veins of the lower limbs were reviewed. Of these patients, 779 were admitted for elective vein ligation and stripping and 221 presented with thrombophlebitis. The latter group was subdivided into four categories according to the mode of management: (1) local heat and anti-inflammatory agents, 60 cases; (2) anticoagulants, 22 cases; (3) phlebotomy, high saphenous ligation and anticoagulation, 4 cases; and (4) ligation and stripping, 135 cases. In category 4 the saphenous is removed in a routine fashion together wih all its tributaries. All perforators are exposed, evacuated of thrombus when present, and ligated subfascially. Thrombi were encountered in one or more perforating veins in 10 patients, but no pulmonary embolism was observed in this group of patients. All instances of documented pulmonary embolism (10 cases) occurred in category 1 with one fatality. The incidence of pulmonary embolism in the elective group of ligation and stripping (without phlebitis) was 0.5%. The data indicate that the surgical approach is safe and preferable to the other modalities for several reasons: (1) It eliminates the varicosities and the phlebitic process simultaneously, (2) a single hospitalization is necessary (cost effectiveness), and (3) no anticoagulants are needed. If, for any reason, surgery cannot be undertaken, then anticoagulants should be employed in an effort to avoid thromboembolism.

Adolescent↗
PubMed1978

Thrombophlebitis of the lower extremities and ABO blood type.

Of 86 medical patients with a hospital discharge diagnosis of thrombophlebitis of the lower extremity, 70 (81%) were of blood type A,B, or AB (non-O). Of the 344 reference patients matched for age, sex, and country, 187 (54%) were of non-O blood type. The estimate of risk ratio of non-O blood type patients to O blood type patients was 3.7 with 90% confidence limits 2.3 and 6.0. The association between non-O blood type and thrombophlebitis of the lower extremity was strongest among the younger patients and women.

ABO Blood-Group System↗
PubMed1978

[Experience in using helium laser therapy for acute anorectal thrombosis and thrombophlebitis].

Clinical observation over 61 cases of acute anorectal thrombosis and thrombophlebitis was carried out. The duration of the disease ranged from some months to 35 years. The clinical observations have proved the advantages of laserotherapy over phototherapy with monochromatic incoherent red light and its high therapeutic activity in acute anorectal thrombosis and thrombophlebitis.

Chronic Disease↗
PubMed1981

Thrombophlebitis migrans in association with ulcerative colitis.

A case of thrombophlebitis migrans in a patient with ulcerative colitis is presented. The occurrence of thrombophlebitis was associated with an exacerbation of ulcerative colitis and responded well with the treatment of the underlying colitis. Evidence for a hypercoagulable state in ulcerative colitis is presented.

Acute Disease↗
PubMedDate not supplied

[Internal jugular thrombophlebitis: complications of the cervical oncological surgery. A case report].

Internal jugular vein thrombophlebitis is an infrequent complications, associated in the past to pharyngeal and amygdaline infections but related today to the use of catheters and intravenous drugs. The present paper reports the case of a patient who underwent total laryngectomy and functional neck dissection, developing recurrent neumonias and sepsis in the postoperative period which were secondary to an homolateral jugular thrombophlebitis. A physical exploration with no findings and the poor resolution of CT scan and ultrasound due to postsurgical alterations, lead to a late diagnosis and fatal evolution, in spite of the medical and surgical treatment.

Bacterial Infections↗
PubMedDate not supplied

[The surgical treatment of superficial thrombophlebitis of the lower extremities].

The work gives an analysis of results of the surgical treatment of superficial thrombophlebitis of lower extremities. Operations were performed on 70 patients. Subcutaneous thrombophlebitis was considered as acute surgical disease. An active surgical tactics is proposed. The authors show that operative treatment is not dangerous for the patients, reduces the time of the hospital and ambulatory treatment of the patients.

Adult↗
PubMedDate not supplied

[The role of hyperlipidemia in the pathogenesis of acute thrombophlebitis of the surface veins of the lower extremities].

Biochemical investigations carried out in patients with acute thrombophlebitis of the lower limb superficial veins showed that 70% of such patients develop marked changes in blood plasma lipid spectrum, hyperlipidemia. Blood serum lipid spectrum was examined in 19 patients with various forms of acute thrombophlebitis of the lower limb superficial veins and in 17 with varicose disease. Histologic material for morphologic examination (a fragment of the great subcutaneous vein near saphenofemoral anastomosis and of the wall near the thrombus) was collected during surgery. Venous wall fragments were examined under a light microscope for lipid content. The findings did not confirm the expected changes in venous wall in hyperlipidemia analogous with arterial wall changes in atherosclerosis. That is why we may propose that hyperlipidemia, though not directly changing venous wall structure, contributes to thrombogenesis process via other mechanisms.

Acute Disease↗