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Seven compounds were isolated from Aster poliothamnus. By means of spectral evidences and crystal analysis, their structures were elucidated as beta-sitosterol, beta-amyrin, daucosterol, spinasterol, stigmasterol, dammara-20, 24-dien-3 beta-ol and epifriedlinol.
Bile and serum cholesterol concentrations were analyzed by the same saponification, extraction and gas chromatographic procedure, utilizing stigmasterol as an internal standard and trifluoroacetate derivatization. The method was rapid and highly sensitive, requiring only 20 to 50 mul of sample. Comparable levels of precision were achieved by parallel analysis of a series of bile and serum samples by the present method and the Abell colorimetric method; a high degree of correlation was found between these two methods.
The petroleum ether extract of Astragalus complanatus R. Br. showed activity for lowering the transaminase levels in mice. From this extract six compounds were isolated. Among them five were identified as rhamnocitrin (I), formononetin (II), stigmasterol (IV), phosphatidylethanolamine (V) and phosphatidylinositol (VI). The other one was shown to be a new p-coumaroyl derivative, 11-O-p-coumarylnepeticin. Their structures were elucidated by spectrometric and chemical analyses. All the six compounds were isolated from this plant for the first time.
The petroleum ether extractive of the bark of Erythrina variegata var. orientalis was fractionated and shown to be composed of wax alcohols and wax acids, alkyl ferulates, alkyl phenolates, stigmasterol, sitosterol, campesterol and possibly citrostadienol/24-methylenelophenol. The ethanol extractive yielded chloroform-soluble and water-soluble bases, identified as erysovine and stachydrine, respectively.
From Pyrrosia gralla four compounds were isolated and identified stigmasterol(I), ursolic acid (II), mangiferin(III) and sucrose(IV) by physical and chemical means. Compounds I and II were obtained from Pyrrosia for the first time.
OBJECTIVE: To study the pharmacologically active components of Eclipta prostrata. METHOD: The components were extracted by alcohol and isolated by silica gel column and subjected to pharmacological screening. RESULT: Four compounds were isolated from E. prostrata, of which two were identified as stigmasterol and alpha-terthienyl. CONCLUSION: alpha-Terthienyl was isolated from the plant for the first time. The EtOAc part of alcoholic extraction exhibits significant hepatoprotective activity against carbon terachloride-induced liver injury in rats.
OBJECTIVE: To investigate the chemical constituents of the whole plant of Drosera peltata var. lunata collected in Tibet. METHOD: Compounds were separated by means of pH gradient extraction and rechromatography on silica gel, and the structures were determined by spectral analysis and physicochemical evidence. RESULT: Five crystalline compounds were obtained and elucidated as plumbagin(1), droserone(2), hydroxydroserone(3), beta-sitosterol(4) and stigmasterol(5) respectively. CONCLUSION: Compound 3 and 5 were isolated from the plant for the first time.
OBJECTIVE: To investigate the chemical constituents of Pistia stratiotes, a kind of duckweed. METHOD: Compounds were separated by chromatography on sillica gel, and their structures were identified by spectral analysis and chemical evidence. RESULT: Four compounds were obtained and identified as stigmasta-4,22-dien-3-one, stigmasterol, stigmasteryl stearate and palmitic acid. CONCLUSION: All the four compounds were isolated from this plant for the first time.
OBJECTIVE: To search for the effective anti-epilepsiy components from the Chinese folk drug Langdu, the root of Euphorbia ebracteolata. METHOD: Chromatography and spectroscopic analysis were used to isolate and elucidate the chemical constituents in the plant. RESULT: Four compounds, namely 10-nonacosanol, 24-methylenecycloartanol, stigmasterol and dacosterol have been isolated from the precipitate of the plant's methanol extract. CONCLUSION: 10-nonacosarnol and 24-methylenecycloartanol were obtained from the root of E. ebracteolate for the first time.
OBJECTIVE: To study the chemical constitutes in Erythrina arborescens. METHOD: Various chromatographic techniques were used to isolate and purify the constituents. The structures were elucidated by spectral analysis and chemical evidence. RESULT: Six compounds were isolated from the plant and identified as alpinumisoflavone, wighteone, daidzein, genistein, vittadinoside and stigmasterol. CONCLUSION: All these compounds were isolated from the plant for the first time.
OBJECTIVE: To study the chemical constituents of Gymnotheca involucrata. METHOD: Separating the constituents by means of chromatography and identifying their structures on the basis of NMR spectra and TLC with authentic samples. RESULT: From the methanolic extract of the whole plant of G. involucrata, three compounds were isolated and identified as kaempferol-4',7-dimethyl-3-O-glucoside, daucosterol and stigmasterol. CONCLUSION: All the three compounds were isolated from this genus for the first time.
OBJECTIVE: To separate and identify the chemical constituents of the whole plant. METHOD: The compounds were extracted with solvents, isolated by column chromatography and identified by spectroscopic methods, such as IR, MS and 1H NMR. RESULT: Five compounds were identified as hentriantane I, taraxasteryl acetate II, taraxasterol III, beta-sitosterol IV, and stigmasterol V. CONCLUSION: The compounds III and V were obtained from the plant for the first time.
Two steroids and two lipids were isolated from the ethanolic extract of Spirodela polyrrhiza. Their structures were identified by spectral analysis and chemical evidence, which were identified as stigmasterol, monopalmitic glycerate, daucosterol and palmitic acid. Monopalmitic glycerate was discovered from this plant for the first time.
OBJECTIVE: To study the chemical constituents from Ampelopsis grossedentata (hand-Mazz) W.T. Wang. METHODS: Chromatography and spectroscopic analysis were employed to isolate and elucidate the chemical constituents in the plant. RESULTS: Seven compounds were isolated and elucidated as ampelopsin (I), myricetin (II), myricitrin (III), gallic acid (IV), beta-sitosterol (V), stigmasterol (VI) and dihydroquercetin (VII). CONCLUSION: Among these compounds, IV, V, VI and VII were isolated from this plant for the first time, and compound VII was obtained from genus Ampelopsis for the first time.
Seven compounds were isolated from Neonauclea sessilifolia. They are paeonol, 3,4-dihydroxybenzoic acid, scopoletin, anthraquinnones chrysophanol, 4H-1-benzopyran-4-one,5,7-dihydroxy-2-methyl, beta-sitosterol and stigmasterol glucoside. These compounds were isolated at first time from this genus and this plant.
Two crystalline components I and II were isolated from the roots of Actinidia kolomikta. I was identified as delta 7-stigmasterol and II was named alpha-kolomiktriose and elucidated as 2, 3-di-0-beta-D-galactopyranosyl-alpha-D-galactopyranose on the basis of spectral data (13C NMR, 1H NMR, IR and EI-MS).
OBJECTIVE: To study the chemical constituents from Lamium maculatum L. var Kansuense. METHOD: The chemical constituents were isolated and repeatedly purified by silica gel column chromatography and the structures were elucidated by the NMR spectra and physico-chemical properties. RESULT: Ten compounds were obtained and they were identified as D-mannitol, beta-sitosterol, stigmasterol, rutin, 3'-methylquercetin-3-O-rutinoside, n-butyl-beta-D-fructopyranoside, daucosterol, acteoside, 20-hydroxyecdysone, allantoin. CONCLUSION: All the compounds were obtained from L. maculatum L. var Kansuense for the first time.
Two new compounds, a stigmasterol (1) and an eremophilenolide (2), were isolated from Ligularia dolichobotrys (Diels) together with ten known sesquiterpenoids, two known triterpenes and five known sterols. Their structures were elucidated by spectroscopic methods (IR, MS, 1H, 13C and 2D NMR). In addition, bakkenolide A (3) exhibited effective antitumor activity to human leukemia cells (HL-60), human hepatoma cells (Bel-7402) and human ovarian neoplasm cells (HO-8910).