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Effect of super-EBA as a root end filling on healing after replantation.

The effect of Super-EBA cement as a root-end filling placed in teeth before replantation was examined in eight molar roots in monkeys. After extraction, root ends were resected, the canals contaminated with oral bacteria, root-end cavities prepared, and fillings of Super-EBA placed before replantation. After 8 wk, the jaws were removed and prepared for histological examination. The tissue response to Super-EBA was very mild, with only a few inflammatory cells being observed at the root end of 3 of the 8 roots filled. Previous work showed a similarly mild response to Intermediate Restorative Material and a very much more severe response to amalgam. It is concluded that the tissue response to Super-EBA as a root-end filling is acceptable and considerably more favorable than that to amalgam.

Animals↗

Surgical apical repair with super-EBA cement: a one-visit alternative treatment to apexification.

This article presents an alternative one-visit treatment to conventional apexification. Time, patient compliance, and multiple office visits are required to complete an apexification successfully. In the technique described, the root canal system is instrumented and filled followed by immediate periradicular manipulation and apical repair with Super-EBA cement. Cases presented in this pilot study have a recall period ranging from 5 to 14 months. It is our contention that the results of this technique are highly predictable, with the added advantage that unsalvageable situations (e.g., vertical root fracture) can be assessed right away. In both instances, the patient will receive the precise prognostic assessment and treatment. Thus, patients are returned to their restorative dentists with minimal delay.

Adolescent↗

Antibacterial effects of some root end filling materials.

In addition to having good sealing ability, root end filling materials should "ideally" have some antibacterial activity to prevent bacterial growth. This investigation compared the antibacterial effects of amalgam, zinc oxide-eugenol, Super EBA and a mineral trioxide aggregate on nine facultative bacteria Streptococcus fecalis, Streptococcus mitis, Streptococcus mutans, Streptococcus salivarius, Lactobacillus species, Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, and Escherichia coli B and seven strict anaerobic bacteria, Prevotella (Bacteroides) buccae, Bacteroides fragilis, Prevotella (Bacteroides) intermedia, Prevotella (Bacteroides) melaninogenica, Fusobacterium necrophorum, Fusobacterium nucleatum, and Peptostreptococcus anaerobius. After growing these bacteria on solid media, freshly mixed and 24-h set test materials were placed on the surface of these inoculated media and incubated in the appropriate atmosphere for 24 to 48 h at 37 degrees C. Impregnated discs with the Super EBA liquid were used as positive controls. The antibacterial effects of each material were measured in millimeters and the data were analyzed using one-way and two-way analysis of variance and Scheffé tests to determine the statistical differences between the antibacterial effects of the test materials. Impregnated discs with Super EBA liquid caused varying degrees of growth inhibition for both facultative and strict anaerobic bacteria. Both types of amalgam had no antibacterial effect against any of the bacteria tested in this study. Mineral trioxide aggregate had an antibacterial effect on some of the facultative bacteria and no effect on any of the strict anaerobic bacteria. Zinc oxide-eugenol and Super EBA pastes had some antibacterial effects on both types of bacteria tested.(ABSTRACT TRUNCATED AT 250 WORDS)

Aluminum Compounds↗

Physical and chemical properties of a new root-end filling material.

This study determined the chemical composition, pH, and radiopacity of mineral trioxide aggregate (MTA), and also compared the setting time, compressive strength, and solubility of this material with those of amalgam, Super-EBA, and Intermediate Restorative Material (IRM). X-ray energy dispersive spectrometer in conjunction with the scanning electron microscope were used to determine the composition of MTA, and the pH value of MTA was assessed with a pH meter using a temperature-compensated electrode. The radiopacity of MTA was determined according to the method described by the International Organization for Standardization. The setting time and compressive strength of these materials were determined according to methods recommended by the British Standards Institution. The degree of solubility of the materials was assessed according to modified American Dental Association specifications. The results showed that the main molecules present in MTA are calcium and phosphorous ions. In addition, MTA has a pH of 10.2 initially, which rises to 12.5 three hours after mixing. MTA is more radiopaque than Super-EBA and IRM. Amalgam had the shortest setting time (4 min) and MTA the longest (2 h 45 min). At 24 h MTA had the lowest compressive strength (40 MPa) among the materials, but it increased after 21 days to 67 MPa. Finally, except for IRM, none of the materials tested showed any solubility under the conditions of this study.

Aluminum Compounds↗

Investigation of mutagenicity of mineral trioxide aggregate and other commonly used root-end filling materials.

Little information is available regarding the mutagenicity of root-end filling materials. To study mutagenicity of Intermediate Restorative Material (IRM), Super-EBA, and a potential root-end filling material, mineral trioxide aggregate (MTA), strains of Salmonella typhimurium LT-2 (TA 98, R-factor strain and TA 1535, non-R-factor strains) were used in a standard Ames mutagenicity assay. Positive controls (S9 protein and benzo-(a)-pyrene and N-methyl-N'-nitro-N-nitrosoguanidine) operated properly. No increase in revertant bacteria colony counts occurred with any of the test materials. Based on these results, it seems that IRM, Super-EBA, and MTA are not mutagenic as measured by the Ames Test.

Aluminum Compounds↗

A comparison of tissue reactions to Ketac-Fil and amalgam.

The objective of this study was to compare the bone tissue reactions of Ketac-Fil to the most commonly used retrograde filling material, amalgam, in a rat model. Forty-eight Harlan rats were divided into three groups: amalgam, Ketac-Fil, and controls. Following anesthesia, the right lower incisor was extracted from each animal. A 3-mm long x 1-mm diameter polyethylene tube filled with amalgam or Ketac-Fil was implanted in the extraction site. The animals were killed at 14, 42, and 90 days; and the mandibles were dissected en block and processed histologically. The inflammatory reaction was assessed by the number of plasma cells, lymphocytes, polymorphonuclear neutrophils, giant cells, and osteoclasts within 100 microns of the implant. Bone formation was determined as either present or absent in the same area. There was no statistically significant bone apposition within 100 microns of the Ketac material, and there was a statistically significant increase in inflammation in the amalgam group. This study indicates that both Ketac-Fil and amalgam are relatively biocompatible, and provides support for clinical usage tests of Ketac-Fil as a retrograde filling material.

Alveolar Process↗

Root end isolation for retrograde fillings.

Isolation and moisture control of the root end of a tooth with a large periapical lesion is normally accomplished with the aid of bone wax, cotton pellets, or sterile gauze saturated with a suitable hemostatic agent. An alternative procedure, a simple and effective rubber dam technique, is presented demonstrating isolation of an apex before reverse filling.

Adult↗

Long-term evaluation of surgically placed amalgam fillings.

The coauthors of this article had developed the clinical impression that whereas surgically placed amalgam fillings are successful on a short-term basis, the long-term prognosis for these cases may not be nearly as favorable. In order to test this hypothesis, as many patients as could be contacted, either directly or indirectly, who had been treated before 1981 were evaluated. Excluded from this study were cases for which failure could be attributed to any reason other than failure from the amalgam reverse filling. Therefore, all cases included had to demonstrate periapical healing prior to ultimate breakdown. On this basis, 60 of 104 teeth (57.7%) were considered to be successful and 44 teeth (42.3%) were determined to be failures.

Dental Amalgam↗

An electrochemical study of the sealing ability of different retrofilling materials.

Eighty-eight extracted mandibular and maxillary cuspids were selected for this study. Eighty cuspids were used as experimental groups and eight were used as controls. Anatomical crowns were resected, root canals were prepared, and the apical 2 mm of the roots were removed. The experimental roots received apical cavity preparations and were randomly divided into four equal groups. The apical cavities were retrofilled with amalgam, heat-sealed gutta-percha, zinc polycarboxylate cement, or glass ionomer cement. Leakage was measured using an electrochemical technique. Statistical analysis of the results indicated that glass ionomer sealed significantly better than the other materials, followed by amalgam, heat-sealed gutta-percha, and zinc polycarboxylate cement, respectively.

Analysis of Variance↗

Preliminary investigation of ultrasonic root end preparation.

Recently, an ultrasonic instrument intended for root end preparation during periapical surgery has become commercially available. This study evaluated root end preparations in 30 extracted human teeth, comparing those prepared with ultrasonic instrumentation to teeth prepared in a traditional manner with a microhandpiece and to teeth prepared using a combination of the microhandpiece and the ultrasonic instrument. Specimens were evaluated for size of preparation, preparation debridement, and time required for preparation. Preparations with the ultrasonic device were found to be significantly smaller than the other techniques evaluated. Traditional and combined techniques resulted in greater debridement under the conditions of the study, and only the combined technique demonstrated an increase in time required for preparation. Ultrasonic instrumentation may provide significant advantages in the treatment of deeply fluted roots when an isthmus is present by reducing the risk of root perforation.

Dental Pulp Cavity↗

A study of the apical microleakage of a gallium alloy as a retrograde filling material.

The feasibility of utilizing mercury-free Gallium alloy GF for retrograde filling was investigated by comparing apical microleakage in 184 extracted human teeth. The teeth were divided into four experimental and two control groups. Three experimental groups were apical cavity retrofillings with the Gallium alloy GF, a mercury-containing amalgam, and a glass ionomer. The fourth experimental group was filled with gutta-percha and heat-burnished after apicoectomy. After 24 h, 1 wk, 4 wk, and 12 wk immersion in dye solution, the roots were vertically sectioned, and the deepest point of dye penetration was recorded. The glass ionomer showed the least leakage, followed by the amalgam group and the gallium group (no significant difference). The gutta-percha heat-burnished group displayed the greatest leakage. Gallium alloy GF was shown to have an equivalent sealing potential to dental amalgam for a retrograde filling material.

Analysis of Variance↗

Periapical surgery in a Norwegian county hospital: follow-up findings of 477 teeth.

Four-hundred seventy-seven teeth treated by periapical surgery by one surgeon were followed up until a stable radiographic situation was recorded. Radiographic findings were classified into one of four groups: 1, complete healing; 2, incomplete healing (scar tissue); 3, uncertain healing; or 4, unsatisfactory healing. Evaluation was performed independently by an endodontist and the oral surgeon and cases of disagreement were subjected to joint evaluation. Difficult cases and borderline cases were judged by an oral radiologist. Complete healing was observed for 78% and incomplete healings (scar tissue) for 9% of the teeth. The size of the latter group was strongly influenced by the number of cases with large preoperative lesions. When the material was grouped as "success" (complete healing, scar tissue healing) and "failure" (uncertain healing, unsatisfactory healing), a 13% failure frequency was recorded. Twenty-eight percent of the cases treated with retrograde fills failed compared with 4% in the orthograde group.

Adult↗

Retrograde filling materials: a retrospective success-failure study of amalgam, EBA, and IRM.

A retrospective study was done to compare the success rates of teeth with three different root end filling materials. The materials studied were SuperEBA, IRM, and zinc-free high-copper spherical amalgam. Radiographs of 488 cases from two geographically distinct offices were used, with the recall period ranging from a minimum of 6 months to a maximum of 10 yr. The cases in each office were examined independently using the same criteria. The results revealed that both SuperEBA and IRM demonstrated statistically significant improvements in success rates when compared with amalgam. The success rates were 75% for amalgam, 91% for IRM, and 95% for SuperEBA. The difference between IRM and SuperEBA was not statistically significant.

Apicoectomy↗

Longitudinal evaluation of the seal of endodontic retrofillings.

The apical seal obtained with various retrofilling materials placed in prepared, extracted human anterior teeth was measured at various time intervals. Materials evaluated were cold-burnished gutta-percha, amalgam, amalgam with a cavity varnish, SuperEBA cement, and a glass ionomer restorative material (Ketac-Silver). Control groups included teeth retrofilled with either gutta-percha without sealer or TERM. The root canals were cleaned and shaped and the root ends were prepared for retrofilling. The materials were placed into the preparations and allowed to set for 24 h. Microleakage was measured at 24 h, 1, 2, and 3 wk, and 1, 2, and 3 months after insertion of the retrofilling using a fluid filtration technique. Multiple range analysis indicated that Ketac-Silver produced a significantly inferior seal when compared with the other materials at all time periods. There was no significant difference among SuperEBA, amalgam, and amalgam with a cavity varnish.

Dental Leakage↗

Dye leakage in retrofilled dog teeth and its correlation with radiographic healing.

In a previous study in beagle dogs, statistically significant differences in healing were observed radiographically 6 months after apicoectomy and retrofilling with amalgam and varnish, glass ionomer cement, or a composite resin. The purpose of this study was to compare the leakage of these retrofilling materials and to correlate leakage data with healing. After the dogs were sacrificed, 48 roots were extracted. Half of the roots had been irradiated with a CO2 laser on the bevelled root surface after retrofilling. The roots were coated with nail polish, except for their bevelled surface, and were suspended together with positive and negative controls in 2% methylene blue for 8 h. After the specimens were longitudinally split, they were ranked according to the severity of dye penetration, as observed with a dissecting microscope. The differences in dye leakage among the three retrofilling materials were not statistically significant. Consequently, dye leakage did not correlate with the previously assessed healing. Dye penetrated into the root through the bevelled root surface, regardless of CO2 laser exposure of that surface.

Animals↗