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Development and validation of a colorectal functional outcome questionnaire.

BACKGROUND: After colorectal surgery, patients often experience impaired functional outcome. Faecal incontinence grading systems and self-assessment questionnaires are frequently used to assess these complaints. The available faecal incontinence grading systems have been validated, but have a limited focus, while more comprehensive questionnaires, which have been developed, have not been validated. AIMS: To investigate the reliability and validity of a newly developed, colorectal functional outcome (COREFO) questionnaire and of Dutch translations of the Hallböök questionnaire and an adapted version of the Vaizey questionnaire. PATIENT/METHODS: Two hundred fifty-seven patients with and without impaired functional outcome after (colorectal) surgery received a booklet containing the three questionnaires in random order by mail. One hundred seventy-nine (70%) completed them, and 160 patients (90%) completed a retest within, on average, 18 days. RESULTS/FINDINGS: Reliability and validity were adequate for the COREFO and Hallböök questionnaire, with slight differences in the psychometric analyses in favour of the COREFO questionnaire. Significantly more patients found the COREFO questionnaire to reflect their problems best. The reliability of the Vaizey questionnaire was not sufficient. INTERPRETATION/CONCLUSIONS: The newly developed COREFO questionnaire and the previously unvalidated Hallböök questionnaire are both suitable instruments to evaluate functional outcome after colorectal surgery. The psychometric analyses showed a slight difference in favour of the COREFO questionnaire and significantly more patients preferred the COREFO questionnaire to the other questionnaires. Therefore, we prefer to use the COREFO questionnaire in future research.

Abdominal Pain↗

Validation of the ISAAC video questionnaire (AVQ3.0) in adolescents from a mixed ethnic background.

BACKGROUND: The International Study of Asthma and Allergies in Childhood (ISAAC) has developed an international version of the asthma video questionnaire (AVQ3.0) to measure asthma prevalence. This questionnaire has not been validated in adolescents from a mixed ethnic background. OBJECTIVE: The aims of this study were to compare the video questionnaire with a written questionnaire in the detection of airway hyperresponsiveness to hypertonic saline in a population of adolescents from a mixed ethnic background, and to establish the repeatability and psychometric properties of the asthma video questionnaire. METHODS: The study was conducted in four secondary schools in Sydney, an area with a high proportion of people from a non-English speaking background. Four hundred and seventy-five students from schools 1 and 2 completed the video questionnaire and a subgroup of these students (n = 170) completed the written questionnaire and a hypertonic saline inhalation challenge. Reproducibility of the questionnaire was evaluated by administering the questionnaire to a subsample of students 2 weeks later. The psychometric properties of the video questionnaire were examined in 852 students at two other schools (schools 3 and 4). RESULTS: One hundred and sixty-nine students aged 13.5 (sd 1.3) years completed both written and video questionnaires, and the hypertonic saline challenge. The students had widely different cultural backgrounds including Asian, South Pacific, Middle Eastern, European and African countries. There was good agreement between the questionnaires for wheeze (kappa 0.42). Questions on the video questionnaire concerning wheezing had good sensitivity (90%) and specificity (68%) for airway hyperresponsiveness to hypertonic saline. The video questionnaire was reproducible (kappa 0.82), had good internal consistency (Cronbach's alpha 0.81) and each question pertained to a single construct explaining 58% of the variance in total score. CONCLUSION: This study has validated the international version of the ISAAC video questionnaire against airway hyperresponsiveness to hypertonic saline in adolescents from a mixed ethnic background, and identified that the questionnaire has good psychometric properties. The ISAAC video has proved to be a valuable tool for the assessment of asthma prevalence in populations of ethnic diversity.

Adolescent↗

Improving response rates to primary and supplementary questionnaires by changing response and instruction burden: cluster randomised trial.

OBJECTIVE: Supplementary questionnaires provide additional information from subgroups, but may have an attritional effect on response rates. We examined the effects of different instruction methods on response rates to a two-part questionnaire. METHODS: The ACT Kindergarten Health Survey comprises a health questionnaire for all school-entry children. A supplementary questionnaire targets children with respiratory symptoms. We cluster-randomised 109 schools in the ACT (4,494 children) to two instruction groups. Group 1 (instruction burden) had instructions to complete the supplementary questionnaire if certain questions in the primary questionnaire were answered. Group 2 (response burden) had instructions to complete both questionnaires irrespective of answers to the primary questionnaire. RESULTS: Instructing all respondents to complete both questionnaires regardless of eligibility resulted in a statistically significantly lower primary questionnaire response rate (82% vs. 87%), but a statistically significantly higher response rate to the supplementary questionnaire (99% vs. 91%). The net effect was a small overall gain (82% vs. 79%) for the response burden group. CONCLUSION: Increasing the response burden had a minor impact on response rate to the primary questionnaire, but increased the response rate for most items to the supplementary questionnaire. IMPLICATIONS: Large surveys may be broken into primary and supplementary questionnaires, if strategies to maximise response rates are used. Questionnaires may need to be modified to take into account the likely attrition on response to either questionnaire resulting from instruction and response burdens.

Child↗

Patients' views on the utility of quality of life questionnaires in head and neck cancer: a randomised trial.

OBJECTIVES: (i) To evaluate head and neck cancer patient perspectives regarding the usefulness of quality of life questionnaires in communicating their health problems to clinicians and (ii) to identify the quality of life questionnaire that head and neck cancer patients find most useful. DESIGN: Randomised questionnaire study. Patients completed all four validated head and neck cancer quality of life questionnaires - European Organisation for Research and Treatment of Cancer (EORTC), Functional Assessment of Cancer Therapy Scale (FACT) HN35, Washington quality of life questionnaire, Auckland quality of life questionnaire. Order of questionnaire presentation was randomised to counterbalance order effects. SETTING: Tertiary referral head and neck cancer centre. PARTICIPANTS: Eighty patients diagnosed and treated for head and neck cancer. EXCLUSION CRITERIA: blindness, learning difficulties or inability to understand or read English. MAIN OUTCOME MEASURES: Patient ratings of perceived usefulness and preferences of studied questionnaires. RESULTS: Patients reported high relevance to their problems and high ease of understanding of all questionnaires, with FACT scoring highest (79% and 89%, respectively); 58% of participants (67% respondents) would like to complete a questionnaire in clinic, as it would help them describe their health problems to their doctors; 28% of participants did not. Almost half preferred a particular quality of life questionnaire, FACT being most preferred. Length of questionnaire did not affect reported usefulness, but most would prefer a short questionnaire (<20 items). CONCLUSIONS: Patients report that head and neck cancer quality of life questionnaires effectively describe their health concerns. Most are in favour of completing quality of life questionnaires in clinic, as an aid for describing health problems to clinicians. There appears to be a difference between clinicians and patients regarding the perceived usefulness of quality of life questionnaires in the clinic setting, which needs to be highlighted to clinicians.

Aged↗

Asthma and asthma-like symptoms in adults assessed by questionnaires. A literature review.

The first widely used questionnaire in respiratory epidemiology was the questionnaire from the Medical Research Council (MRC) of Great Britain. In the first version, from 1960, there were only a few questions about wheezing, but in later editions, more questions about asthma and asthma-like symptoms were added. The MRC questionnaire initiated the development of other questionnaires such as the European Community for Coal and Steel (ECSC) questionnaire of respiratory symptoms and the questionnaire from the American Thoracic Society and the Division of Lung Diseases (ATS-DLD-78). In Tucson, Ariz, a questionnaire was developed in the 1970s that was focused on the subject's own report of asthma. In Great Britain, a questionnaire was developed in the 1980s with the intention of finding the most valid symptom-based items for identifying asthma, "the IUATLD (1984) questionnaire." When judging the validity of a questionnaire, it is essential to understand sensitivity and specificity. Sensitivity is the fraction of the truly diseased subjects found to be diseased using the questionnaire. Specificity is the fraction of the truly healthy subjects found to be healthy using the questionnaire. Regarding questionnaires dealing with asthma, the situation is confusing because of the absence of any gold standard for asthma. The most usual mode of validation has been to test the questionnaire against the results of a clinical physiologic investigation, often a nonspecific bronchial challenge test. Another approach has been to compare the answers from the questionnaire with the clinical diagnoses of asthma. When validated in relation to bronchial challenge tests, the questions about self-reported asthma have a mean sensitivity of 36 percent (range, 7 to 80 percent) and a mean specificity of 94 percent (range, 74 to 100 percent). The questions about "physician-diagnosed asthma" have even higher specificity, 99 percent. When validated in relation to a clinical diagnosis of asthma, the mean sensitivity for the question about self-reported asthma was 68 percent in the reviewed studies (range, 48 to 100 percent). The specificity was 94 percent (range, 78 to 100 percent). One problem in using the presence of bronchial hyperreactivity (BHR) as a gold standard for asthma is that many people with BHR report no respiratory complaints. In other words, the presence of BHR is a measure with high sensitivity but low specificity for asthma. The effect of using a methacholine challenge test as a standard for the disease will thus be an underestimation of the sensitivity of the questionnaire.(ABSTRACT TRUNCATED AT 400 WORDS)

Adult↗

Psychological questionnaires: do "abnormal" scores precede or follow first-time low back pain?

STUDY DESIGN: A prospective study of psychological risk factors for first-time low back pain with repeated use of psychological questionnaires. OBJECTIVES: To measure the reproducibility of scores from psychological questionnaires, and to compare this with changes that follow an individual's first attack of back pain. Secondly, to determine which scores predict first-time back pain. SUMMARY OF BACKGROUND DATA: "Abnormal" psychometric scores are associated with several aspects of back pain behavior. Little is known, however, about their reproducibility or long-term stability, and there has been no definitive answer to the question: which comes first, "abnormal" scores or low back pain? METHODS: 403 volunteers with no history of "serious" low back pain (defined as pain requiring medical attention or absence from work) participated in a functional spinal assessment. At the time of initial assessment and at 6-month intervals thereafter, the volunteers completed the following questionnaires: the Health Locus of Control, which was subdivided into three sections labelled "Internal," "Powerful others," and "Chance"; the Modified Somatic Perception Questionnaire; and the Zung depression scale. Scores from the Modified Somatic Perception Questionnaire and from the Zung depression scale were added to form a measure of psychological distress. Additional questionnaires inquired about any back pain experienced in the previous 6 months. Only three volunteers had left the study at the 18-month follow-up. At that time 162 participants had reported "any" low back pain, of which 79 were "serious." RESULTS: Intraclass correlation coefficients for scores repeated after 6 months ranged from 0.67-0.80, and reproducibility of scores was equally high between the 0-, 6-, 12- and 18-month assessments. None of the scores were affected by "any" low back pain, and only the Modified Somatic Perception Questionnaire scores changed after "serious" back pain was reported. In a multivariate analysis, the most significant predictor of first time "serious" or "any" back pain was a history of non-"serious" back pain (P < 0.001). Of the psychological factors, the sum of Modified Somatic Perception Questionnaire scores and Zung questionnaire scores was the best predictor of "serious" back pain (P = 0.037), and the Modified Somatic Perception Questionnaire score was the best predictor of "any" back pain (P = 0.002). The 25% of participants with the highest sum of scores from the Modified Somatic Perception Questionnaire and Zung questionnaire was 2.7 times more likely to develop "serious" back pain than the 25% with the lowest sum of these scores. Nevertheless, after accounting for the affects of a history of non-"serious" back pain, psychometric scores predicted less than an additional 3% of reported back pain. CONCLUSIONS: The scores from the Modified Somatic Perception Questionnaire and Zung questionnaire were reproducible over 18 months and were affected little by first episodes of back pain; yet these scores were significant predictors of it. "Abnormal" scores from these questionnaires precede back pain in a small number of people.

Adolescent↗

Web-based and mailed questionnaires: a comparison of response rates and compliance.

BACKGROUND: We assessed response rates and compliance for a printed questionnaire and a Web questionnaire in a Swedish population-based study and explored the influence of adding personalized feedback to the Web questionnaire. METHODS: We assigned 875 subjects to 1 of 3 groups: printed questionnaire, plain Web questionnaire, or Web questionnaire with personalized feedback. The questionnaire had 2 parts, first a general section and then a dietary section. RESULTS: The response rate for the general section was 64% for the printed questionnaire, compared with 50% for the Web questionnaire with feedback. For the dietary questionnaire, the rates were reversed, resulting in a total response rate for the dietary questionnaire that did not differ between printed and web questionnaire with feedback. CONCLUSIONS: Interactivity in the Web questionnaire increased compliance in completion of the second section of the questionnaire. Web questionnaires can be useful for research purposes in settings in which Internet access is high.

Adult↗

A study of non-response in a questionnaire survey of parents' views of paediatric care.

The aim of this study was to examine whether there were differences in quality ratings between respondents and non-respondents to a questionnaire concerning parents' views of paediatric care. This study also examined whether quality ratings differed when questionnaire respondents were asked to reassess certain aspects of hospital care in a follow-up questionnaire. A total of 1094 questionnaires were distributed to parents at the hospital. Three weeks later, follow-up questionnaires were sent home to a random sample of 140 parents who had visited the hospital during the 2 weeks when the main questionnaire was distributed. Forty-six per cent of respondents to the follow-up questionnaire had never received the original questionnaire in hospital, while only seven individuals in the follow-up sample were active non-respondents. Analysis of variance revealed that respondents to the follow-up questionnaire who had never received the main questionnaire did not differ significantly from respondents to the main questionnaire in their ratings of key quality domains. There were no statistically significant differences in quality ratings between parents who responded to both questionnaires and parents who responded to the main questionnaire. For hospital management, it is important to be able to trust questionnaire results. Non-response bias can jeopardize the validity of questionnaire results, which is why studies of non-response are important. The current study pinpoints a number of difficulties that need to be considered when conducting investigations of non-response.

Adolescent↗

Increasing response rates to postal questionnaires: systematic review.

OBJECTIVE: To identify methods to increase response to postal questionnaires. DESIGN: Systematic review of randomised controlled trials of any method to influence response to postal questionnaires. STUDIES REVIEWED: 292 randomised controlled trials including 258 315 participants INTERVENTION REVIEWED: 75 strategies for influencing response to postal questionnaires. MAIN OUTCOME MEASURE: The proportion of completed or partially completed questionnaires returned. RESULTS: The odds of response were more than doubled when a monetary incentive was used (odds ratio 2.02; 95% confidence interval 1.79 to 2.27) and almost doubled when incentives were not conditional on response (1.71; 1.29 to 2.26). Response was more likely when short questionnaires were used (1.86; 1.55 to 2.24). Personalised questionnaires and letters increased response (1.16; 1.06 to 1.28), as did the use of coloured ink (1.39; 1.16 to 1.67). The odds of response were more than doubled when the questionnaires were sent by recorded delivery (2.21; 1.51 to 3.25) and increased when stamped return envelopes were used (1.26; 1.13 to 1.41) and questionnaires were sent by first class post (1.12; 1.02 to 1.23). Contacting participants before sending questionnaires increased response (1.54; 1.24 to 1.92), as did follow up contact (1.44; 1.22 to 1.70) and providing non-respondents with a second copy of the questionnaire (1.41; 1.02 to 1.94). Questionnaires designed to be of more interest to participants were more likely to be returned (2.44; 1.99 to 3.01), but questionnaires containing questions of a sensitive nature were less likely to be returned (0.92; 0.87 to 0.98). Questionnaires originating from universities were more likely to be returned than were questionnaires from other sources, such as commercial organisations (1.31; 1.11 to 1.54). CONCLUSIONS: Health researchers using postal questionnaires can improve the quality of their research by using the strategies shown to be effective in this systematic review.

Data Collection↗

Self-reports of HIV risk factors by patients at a sexually transmitted disease clinic: audio vs written questionnaires.

OBJECTIVES: The purpose of this study was to determine how the method of assessment affects patient report of human immunodeficiency virus (HIV) risks. METHODS: Patients at a sexually transmitted disease clinic randomly received either a written self-administered questionnaire or an audio self-administered questionnaire delivered by cassette player and headset. These questionnaires were followed by face-to-face interviews. RESULTS: Audio questionnaires had fewer missing responses than written questionnaires. Audio questionnaires also identified more unprotected vaginal intercourse and sexual partners suspected or known to have HIV infection or acquired immunodeficiency syndrome than did written questionnaires. Although both the audio and written questionnaires identified more risks than the face-to-face interviews, the difference in the mean number of reported risks between the audio questionnaires and the face-to-face interviews was greater than that between the written questionnaires and the face-to-face interviews. CONCLUSIONS: Audio questionnaires may obtain more complete data and identify more HIV risk than written questionnaires. Research is warranted about whether audio questionnaires overcome barriers to the completion and accuracy of HIV risk surveys. This study emphasizes the need to elucidate the relative strengths and weaknesses of written questionnaires, audio questionnaires, and face-to-face interviews for HIV risk assessment.

Adolescent↗

Follow-up by mail in clinical trials: does questionnaire length matter?

In large clinical trials where outcome assessment is possible using questionnaires, it may be more cost-effective to mail them to patients than to conduct interviews in-person. However, nonresponse to mailed questionnaires reduces the effective sample size and can introduce bias. We conducted a systematic review and meta-analysis of randomized controlled trials evaluating the effect of questionnaire length on response rates. We searched 14 electronic bibliographic databases, the reference lists of relevant trials, and we contacted the authors of eligible trials to ask about unpublished data. For each trial identified, we used logistic regression to estimate the odds ratio for response per one page increase in the number of pages included in the questionnaire. We pooled the regression coefficients in a random effects meta-analysis. Heterogeneity among the coefficients was assessed using a chi-square test at a 5% significance level. We specified a priori that the reduction in the odds of response per one page increase would be greatest among trials comparing relatively short questionnaires. We used meta regression to examine the relationships between the regression coefficients, the length of the questionnaires used in each trial, and other study characteristics. A total of 38 randomized controlled trials were identified where participants were allocated to questionnaires of differing lengths and where the number of pages used was known. There was significant heterogeneity between the regression coefficients estimated from each trial. In meta regression, most of the heterogeneity was explained by variation in the length of the questionnaires used in each trial. Among trials in which the shortest questionnaire was a postcard, the odds of response were more than halved for each additional page used (0.39; 95% CI 0.34 to 0.45). In the remaining trials, pooled effect sizes were much smaller. In trials of one page compared with either two or three pages, the odds of response per one page increase was 1.01 (95% CI 0.82 to 1.24). For one page compared with four or more pages, and for two or more pages compared with longer alternatives, the odds ratios per one page increase were 0.90 (95% CI 0.83 to 0.98) and 0.98 (95% CI 0.96 to 0.99), respectively. There were no statistically significant associations between trial results and other study characteristics. It appears that response can be increased by using a shorter questionnaire. Moderate changes to the length of shorter questionnaires will be more effective than moderate changes to the length of longer questionnaires. If a choice of follow-up questionnaire exists for a clinical trial, the shorter one should be used. If a new follow-up questionnaire is to be designed, it should be made as short as possible without compromising the data collection requirements of the trial.

Follow-Up Studies↗

Developing a standard short questionnaire for the assessment of patient satisfaction with out-of-hours primary care.

BACKGROUND: Governmental reviews of out-of-hours services in England and Scotland have recommended that a standard questionnaire should be used to assess patient satisfaction. This is important because of the rapid introduction of new forms of care. OBJECTIVE: To produce a brief, reliable and valid measure of patient satisfaction for use by a wide variety of providers of out-of-hours primary care. METHODS: The Short Questionnaire for Out-of-Hours care was designed and compared with a longer questionnaire which had been validated and used in earlier research. Questionnaires were sent to 1906 people contacting an out-of-hours GP co-operative. Three versions of the short questionnaire were used with different formats. Analysis compared the response rates, measurement properties, concurrent and construct validity of the short and long questionnaires, and of different versions of the short questionnaire. RESULTS AND CONCLUSIONS: There was no significant difference in the overall response rates obtained from the short or long questionnaires (45.7% versus 41.9%; P = 0.17). The effective response rate of questionnaires from which all satisfaction scales could be calculated was higher for the short questionnaire (43.0% versus 36.4%; P = 0.01). There were no significant differences in response rates or distribution of responses between different versions of the short questionnaire. There was moderate agreement between items on the short questionnaire and corresponding scales on the long questionnaire. Scores using the short questionnaire showed anticipated relationships with the age and sex of patients and with characteristics of how the service was delivered. The SQOC is valid and reliable for routine service use.

After-Hours Care↗

The assessment of physical activity by leisure-time physical activity questionnaires.

The assessment of physical activity by questionnaire is currently the most popular and practical method of quantifying physical activity levels. Many questionnaires, past and present, have considered overall or habitual physical activity, which includes occupational (or nonleisure) activity. Others have focused specifically on leisure-time physical activity (LTPA) owing to the recognition of its dominating contribution to the total physical activity of developed populations. This review covers questionnaires that wholly or in part attend to LTPA levels. Typically, self-complete or interviewer-administered questionnaires record information on the types, frequency and duration of activities performed over a particular period of time. Activity-specific energy cost values, expressed in metabolic equivalents (METS) or kilocalories, are then commonly used to estimate the total energy expenditure from all activities and/or categories of activities. The validation of LTPA questionnaires has had to rely upon indirect methods, such as the assessment of cardiorespiratory fitness, body composition and activity diaries. The reporting of the reliability of questionnaires has frequently been ignored, although in cases where it has been reported, doubt exists as to whether the consistency of the questionnaire or the consistency of subjects' physical activity habits were being examined. LTPA questionnaires first appeared in the literature in the mid-1960s for use among specific, mainly middle-aged male population groups. Though they varied in their modes of scoring, periods of activity recall, and overall complexity, associations were universally observed between physical activity levels and chronic health conditions. However, it became apparent that different questionnaires did not yield the same results. In 1978, a questionnaire to assess only LTPA, the Minnesota LTPA Questionnaire, was published and despite its substantial limitations, has since established itself as the most popular option available. In recent years, shorter and simpler alternatives have been advocated, though most have yet to be adequately scrutinised. Associations have been found between LTPA and fitness levels, prompting the use of LTPA questionnaires in large-scale fitness surveys of both adults and children. Although LTPA has continued to be estimated in terms of energy expenditure, little attempt has been made to extend existing knowledge on the energy cost of physical activities. Existing values do not accommodate for individual intensities and inter-population activity variations. Consequently, standardised questionnaires are not yet viable. There exists considerable scope for further work with LTPA questionnaires, especially since the association between coronary heart disease and physical activity is now well recognised. Efforts ought to be directed at wider social groups for whom leisure-time activity may have distinct implications.

Humans↗

Lead poisoning risk determination in an urban population through the use of a standardized questionnaire.

BACKGROUND: The Centers for Disease Control and Prevention (CDC) has recommended using a five-item questionnaire at every regular office visit for all children 6 to 72 months of age to identify those at risk of high-dose exposure to lead. OBJECTIVE: To determine how well the questionnaire identifies children with elevated lead levels. RESEARCH DESIGN: Comparison of results of the questionnaire, which is intended to identify children as being low-risk or high-risk for lead poisoning, with children's blood lead levels. SETTING: A pediatric continuity clinic located in a major teaching hospital in Rochester, NY. PATIENTS: A consecutive sample of 476 children aged 6 to 72 months without a prior history of lead poisoning who were seen in the clinic in July and August 1992, and (for those aged < 36 months) or 12 months (for those aged 36 to 72 months). MEASUREMENTS AND MAIN RESULTS: Fingerstick lead samples were obtained from all children, and those > or = 15 micrograms/dL (0.72 mumol/L) were confirmed by subsequent venous lead determinations. Twenty-eight percent had blood lead levels > or = 10 micrograms/dL (0.48 mumol/L), 8% had levels > or = 15 micrograms/dL (0.72 mumol/L), and 5% had lead levels > or = 20 micrograms/dL (0.96 mumol/L). According to responses on the questionnaire, 44% were initially classified as low-risk, and 43% were high-risk. In 13% risk could not be determined because one or more items on the questionnaire had not been answered or were answered equivocally, whereas all other items were answered "No." Children for whom risk could not be determined were presumed to be at high risk and were added to that category, resulting in 56% of the study population so designated. The questionnaire was moderately effective in identifying children with elevated lead levels. Seventy percent of children having lead levels > or = 10 micrograms/dL (0.48 mumol/L) and 82% of children having lead levels > or = 15 micrograms/dL (0.72 mumol/L) had been classified as high-risk by the questionnaire. Children classified as low-risk were very unlikely to have elevated lead levels. Eighty-one percent of low-risk children had lead levels < 10 ug/dL, and 97% had lead levels < 15 ul/dL. An abbreviated questionnaire using only the first three items from the CDC questionnaire had almost identical effectiveness. CONCLUSIONS: In this clinical setting, in which children are largely urban, poor, and have a moderate to high risk of developing elevated lead levels, the CDC risk assessment questionnaire is effective in identifying children with elevated lead burdens. However, an abbreviated version of the questionnaire may be as effective as the complete questionnaire. Additional questions should be added to the questionnaire to improve its overall sensitivity, and the questionnaire should be tested in other settings to see if it is effective with children having different environmental exposures to lead.

Centers for Disease Control and Prevention, U.S.↗

Validity and reliability of the Modified Manchester Health Questionnaire in assessing patients with fecal incontinence.

PURPOSE: To date, no measures of fecal incontinence severity or its impact on quality of life have been validated for telephone interview. This study was designed to 1) compare responses of a self-administered and a telephone-administered Fecal Incontinence Severity Index; 2) compare a self-administered Fecal Incontinence Quality of Life Scale to the Manchester Health Questionnaire after modifying the latter for telephone administration and American English (Modified Manchester Health Questionnaire); 3) assess test-retest reliability of the telephone-administered Modified Manchester Health Questionnaire; and 4) assess the internal consistency of the Modified Manchester Health Questionnaire subscales. METHODS: Consecutive, English-speaking, nonpregnant females known to have fecal incontinence were invited to participate. Two validated paper questionnaires accompanied the letter informing them of the study: Fecal Incontinence Severity Index and Fecal Incontinence Quality of Life Scale. Consenting patients were contacted for the initial telephone administration of the Modified Manchester Health Questionnaire, and patients who agreed to continue the study were contacted for a repeat telephone administration of the Modified Manchester Health Questionnaire two to four weeks after completing the first interview. RESULTS: Fifty-one females were invited to participate in the study; however, 13 declined or were ineligible. Thirty females, aged 49.3 +/- 10.3 years, returned self-administered questionnaires and completed the first telephone interview, and 21 completed a second telephone interview after an average interval of 23 days. The telephone-administered Fecal Incontinence Severity Index scores were significantly lower than those yielded by the self-administered Fecal Incontinence Severity Index, (6.19 vs. 9.85; P < 0.001), but the telephone and written administrations were significantly correlated (r = 0.5; P < 0.02). Correlations between the Modified Manchester Health Questionnaire quality of life subscales and the paper Fecal Incontinence Quality of Life subscales ranged from 0.6 to 0.9 (median, r = 0.81). The correlation between the total score for the Fecal Incontinence Quality of Life and the total score for the Modified Manchester Health Questionnaire quality of life scales was 0.93 (P < 0.001). Test-retest reliability for the eight Modified Manchester Health Questionnaire subscales ranged from 0.55 to 0.98 (median, r = 0.83), and test-retest reliability for the two telephone administrations of the Fecal Incontinence Severity Index was r = 0.75. Cronbach's alpha for the eight Modified Manchester Health Questionnaire subscales ranged from 0.79 to 0.92 (median, alpha = 0.85). CONCLUSIONS: Telephone-administered versions of the Modified Manchester Health Questionnaire showed good-to-excellent validity, internal consistency, and test-retest reliability. The telephone-administered Fecal Incontinence Severity Index yielded lower severity scores than the written Fecal Incontinence Severity Index; however, the difference (3.66 units) was not clinically significant.

Adult↗

Cognitive interviewing: verbal data in the design and pretesting of questionnaires.

PURPOSE: The purpose of this paper is to discuss problems that occur in questionnaire responses and how cognitive interviewing can be used to identify problematic questions prior to using the questionnaire in the field. BACKGROUND: Questionnaire design involves developing wording that is clear, unambiguous and permits respondents successfully to answer the question that is asked. However, a number of problems in relation to respondents' understanding and successfully completing questionnaires have been identified. Cognitive interviewing, an amalgamation of cognitive psychology and survey methodology, has been developed to identify problematic questions that may elicit response error. The overall aim is to use cognitive theory to understand how respondents perceive and interpret questions and to identify potential problems that may arise in prospective survey questionnaires. METHODS: A literature review is used to examine the process of questionnaire design and how cognitive interviewing can be used to reduce sampling error and increase questionnaire response rates. FINDINGS: Cognitive interviewing involves interviewers asking survey respondents to think out loud as they go through a survey questionnaire and tell them everything they are thinking. This allows understanding of the questionnaire from the respondents' perspective rather than that of the researchers. Cognitive interviews have been used in a number of areas in health care research to pretest and validate questionnaires and to ensure high response rates. Interviewing has been found to be highly effective in developing questionnaires for age specific groups (children and adolescents) and in ascertaining respondents' understanding in health surveys prior to distribution. However, cognitive interviews have been criticized for being overly subjective and artificial. CONCLUSION: Cognitive interviews are a positive addition to current methods of pretesting questionnaires prior to distribution to the sample. They are most valuable in pretesting questions that are complex, where questions are sensitive and intrusive and for specific groups for whom questionnaire completion may pose particular difficulties.

Cognitive Science↗

Estimation of reproducibility and relative validity of the questions included in the EPIC Physical Activity Questionnaire.

BACKGROUND: The EPIC core questionnaire on lifestyle contains a number of questions on physical activity designed to rank subjects according to level of physical activity (short PA questionnaire). These questions are based on a more extensive questionnaire designed to measure absolute total energy expenditure (extensive PA questionnaire), that was validated in a pilot study preceding EPIC. Reproducibility and relative validity of the short PA questionnaire were estimated by selecting, from the pilot study data, the answers to a number of questions from the extensive questionnaire that resembled those actually included in the short version. METHODS: The population of the pilot study consisted of 126 men and women aged between 20 and 70 years. Reproducibility was estimated by administering the extensive questionnaire three times: at baseline, and after 5 and 11 months. In order to determine the relative validity of the extensive questionnaire, a 3-day activity diary, repeated four times, was used as the reference method. RESULTS: Over the study period (13 months), mean absolute energy expenditure, estimated from the questions included in the short questionnaire, was fairly constant in men but not in women. REPRODUCIBILITY: Spearman correlation coefficients ranged from 0.47 to 0.89 in men, and from 0.49 to 0.81 in women. RELATIVE VALIDITY: Spearman correlation coefficients between the short questionnaire and the diary were between 0.32 and 0.81 for men, and between 0.28 and 0.72 for women. CONCLUSIONS: The questions selected for the short questionnaire are not suitable for estimating energy expenditure at an absolute level. Reproducibility and relative validity of the ranking of subjects seemed satisfactory and comparable to the extensive questionnaire. The results imply that the short questionnaire is suitable for ranking subjects in the EPIC study.

Adult↗

Response rate to mailed epidemiologic questionnaires: a population-based randomized trial of variations in design and mailing routines.

Although self-administered questionnaires are major sources of information in epidemiology, comparatively little has been done to study practical aspects of design and mailing. The objective of this study was to evaluate various measures taken to increase the response rate. A questionnaire was mailed in July 1995 to a random sample (n = 2,000) of the Swedish population aged 20-79 years. Using a randomized factorial study design, the questionnaire and mailing procedures were changed in three ways: preliminary notification, length of the questionnaire, and mention of telephone contact. The overall questionnaire retrieval rate was 49%. Preliminary notification (adjusted odds ratio of receiving a completed questionnaire = 1.30, 95% confidence interval (CI) 1.08-1.56 relative to the absence of preliminary notification) and short length of the questionnaire (odds ratio = 1.24, 95% CI 1.04-1.48 relative to a long questionnaire) were both independently associated with a higher retrieval rate. Of eight possible combinations, the one comprising preliminary notification, a short questionnaire, and no mention of telephone contact gave the highest retrieval rate, 56%. The lowest retrieval rate, 40%, was observed for the combination of no preliminary notification, a long questionnaire, and mention of telephone contact. Young age, male sex, and urban residence significantly lowered the retrieval rate. Although there was a positive association between the questionnaire retrieval rate and partial nonresponse (missing answers in retrieved questionnaires), the marginal losses due to the latter did not cancel the gains by optimized mailing routines. Old age was the strongest determinant of partial nonresponse. The data provide evidence that design and mailing strategies, as well as demographic characteristics, may greatly influence the response rate of mailed epidemiologic questionnaires.

Adult↗