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At least 217 records · Page 12Linked to original sources

Suitability of slit lamp retroillumination photographs for classifying cataracts according to 'Lens Opacities Classification System II (LOCS II)'.

The Lens Opacities Classification System II (LOCS II) utilizes photographic standards (two retroilluminated Neitz-CTR and one standard slit lamp Zeiss photographs) for the classification of cortical and posterior subcapsular cataracts, nuclear color and nuclear opalescence. However, dedicated photographic devices, particularly retroillumination cameras, are not always available and this study was aimed at evaluating the suitability of a retroillumination photographic technique with a standard slit lamp camera for cortical and posterior subcapsular cataract classification according to LOCS II. Two observers examined 273 eyes. Kappa statistics demonstrated that agreement between the standard slit lamp, clinical grading (according to published LOCS II methodology) and photographic grading (according to our photographic technique), as well as inter- and intraobserver reproducibility, were excellent (Kappa > 0.74) for the classification of all lenticular regions. The results indicate that a standard slit lamp camera can be as useful as a dedicated retroillumination camera when LOCS II standards are used for cataract classification.

Adult↗

The effect of high pressure sodium vapor lamps on the rat.

The effect of high pressure sodium vapor lamps and daylight-simulating fluorescent lights on the growth, hematology, and behavior of Sprague-Dawley rats has been investigated. Rats weaned under the sodium vapor lamps had slightly heavier adrenals than those exposed to the daylight lamps when the two lighting systems were equalized either for total irradiance or for scotopic illuminance. However, no differences were observed in the tail-flick response, hot plate response, or swimming endurance of rats housed under the two lighting conditions. No consistent differences were seen in the hemoglobin, red and white cell count, hematocrit, and mean cell volume between rats weaned under the high pressure sodium vapor lamps and daylight-simulating fluorescent lights.

Adrenal Glands↗

Repositioning the laser in situ keratomileusis flap at the slit lamp.

PURPOSE: To describe the indications and technique for repositioning the laser in situ keratomileusis (LASIK) flap at the slit lamp. METHODS: We present a description of patients with striae or slippage of the flap who had repositioning of the flap at the slit lamp. RESULTS: Indications for repositioning at the slit lamp are mostly flap striae. However, it can also be done for a displaced flap and small amounts of debridement. This procedure is not recommended for taking cultures, irrigation of diffuse lamellar keratitis, suturing the flap, or epithelial ingrowth. Repositioning the flap is done by finding the edge of the flap with the cannula, lifting the flap, sweeping the cannula to release the entire wound, and infusing balanced salt solution under the entire flap. We did not encounter infection or recurrent epithelial erosion in these patients. CONCLUSIONS: Repositioning the LASIK flap at the slit lamp was effective and safe in the treatment of striae or flap slippage. It saved time, money, and, anxiety for the patient.

Adult↗

[Calculating method for the necessary lamps and sterile rate in a tube-shaped ultraviolet air washer].

It has much more advantage to use the cylindric ultraviolet air washer than to use the ordinary ultraviolet lamps. There was a calculation method for determining necessary lamps in a rectangled ultraviolet air washer, but it had a limiting condition. This paper developed two calculating methods for determining necessary lamps and its sterile rate in a tube-shaped ultraviolet air washer. The sterile rate can be extracted with any parameter. Necessary lamps can also be extracted with its sterile rate.

Air Microbiology↗

Photobiological effects of polychromatic medium pressure UV lamps.

Ultraviolet (UV) light has become widely accepted for the disinfection of potable water, process water and wastewater as an alternative to chlorination. To avoid the failure of a UV disinfection system due to the recovery of micro-organisms, certain additional wavelengths in the UV area are emitted by newly developed UV lamps. To reduce the chance of microbial recovery after ultraviolet irradiation, damage must be inflicted in as many areas of the micro-organism as possible. The effective killing of micro-organisms by improved polychromatic medium pressure UV lamps is due to their exceptionally high UV energy output at specific wavelengths across a broad section of the UV spectrum. The combination of these properties results in several different lethal effects in small and large micro-organisms. Important biological molecules other than DNA are likely to be damaged, which helps to prevent the recovery of irradiated micro-organisms. Absorption line spectra of absorbing nucleotide bases, DNA and other biological molecules, including proteins and enzymes, show how effective UV light can be. Recent findings on the biological effects of short wavelengths on Bacillus subtilis, Cryptosporidium parvum and Escherichia coli confirm the effect of short wavelengths. Practical comparisons with conventional low pressure UV lamps at equal UV dosages show better killing rates from polychromatic medium pressure lamps, without formation of disinfection byproducts (DBPs).

Disinfection↗

Comparison of fluorescent and high-pressure sodium lamps on growth of leaf lettuce.

Radiation from high-pressure sodium (HPS) lamps provided more than a 50% increased yield (fresh and dry weight of tops) of loose-leaf lettuce cultivars Grand Rapids Forcing and RubyConn, compared to that obtained by radiation from cool-white fluorescent (CWF) lamps at equal photosynthetic photon flux; yet, input wattage was approximately 36% less. It was postulated that the considerable output of 700 to 850 nm radiation from the HPS lamp was a significant factor of the increased yield. Under HPS lamps, the leaves of both cultivars were slightly less green with very little red pigmentation ('RubyConn') and slightly elongated, compared to CWF, but plant productivity per unit electrical energy input was vastly superior with HPS.

Biomass↗

[Narrow-band UVB phototherapy (Philips TL01 lamps) in psoriasis].

The authors report the results of an open study conducted on 53 patients with psoriasis treated by narrow-band UVB phototherapy, using Philips' TL01 lamp. With a simple procedure which did not require MED determination this treatment gave satisfactory results in 92 p. 100 of the cases, with mild burns in only 9 p. 100. The morphological type of psoriasis (patchy, guttate or nummular) had no influence on the therapeutic result, but the degree of infiltration of the lesions and their location on the lower limbs proved to be a factor of relative resistance. In most patients the results were obtained in 20 sessions with a mean cumulative dose of 20.19 +/- 2.7 J/cm2. Some patients had an additional treatment of 6 sessions. The results obtained with Philips' TL01 lamp were as satisfactory as those obtained with the conventional UVB lamps, but the TL01 lamp seemed to be easier to handle and better tolerated, which gives them some advantages over the latter.

Adolescent↗

[Different effects of illumination with xenon and sulfur lamp on growth and development of cotton plants].

Experiments were carried out with cotton (Gossgpium hirsutum cv. Xuzhou 142) plants to study the effects of illumination with xenon and sulfur lamp on development of cotton plants. The results showed that, compared with xenon lamp, illumination with sulfur lamp inhibited excessive elongation of hypocotyl via promotion of longitudinal elongation of epidermis and cortex cells, increased the numbers of branches, buds and bolls significantly. It suggested that illumination with sulfur lamp rendered cotton photomorphogenesis more favorable to yield formation.

Gossypium↗

Curing efficacy of a new generation high-power LED lamp.

This study investigated the curing efficacy of a new generation high-power LED lamp (Elipar Freelight 2 [N] 3M-ESPE). The effectiveness of composite cure with this new lamp was compared to conventional LED/halogen (Elipar Freelight [F], 3M-ESPE; Max [M], Dentsply-Caulk) and high-power halogen (Elipar Trilight [T], 3M-ESPE; Astralis 10 [A], Ivoclar Vivadent) lamps. Standard continuous (NS, FS, TS; MS), turbo (AT) and exponential (NE, FE, TE) curing modes of the various lights were examined. Curing efficacy of the various lights and modes were determined by measuring the top and bottom surface hardness of 2-mm thick composite specimens (Z100, 3M-ESPE) using a digital microhardness tester (n=5; load=500 g; dwell time=15 seconds) one hour after light polymerization. The hardness ratio was computed by dividing HK (Knoops Hardness) of the bottom surface by HK of the top surface. The data was analyzed using one-way ANOVA/Scheffe's test and Independent Samples t-test at significance level 0.05. Results of the statistical analysis were as follows: HK top--E, FE, NE > NS and NE > AT, TS, FS; HK bottom--TE, NE > NS; Hardness ratio--NS > FE and FS, TS > NE. No significant difference in HK bottom and hardness ratio was observed between the two modes of Freelight 2 and Max. Freelight 2 cured composites as effectively as conventional LED/halogen and high-power halogen lamps, even with a 50% reduction in cure time. The exponential modes of Freelight 2, Freelight and Trilight appear to be more effective than their respective standard modes.

Composite Resins↗

Early surface microhardness of a resin composite exposed to a pulse-delayed curing exposure: a comparison of a tungsten halogen and a plasma arc lamp, in vitro.

Surface microhardness numbers of a commercial resin composite have been compared after exposure to a quartz tungsten halogen (QTH) and plasma arc (PAC) lamp respectively, using two exposure protocols. The effect of increased tip-to-composite distance has also been compared. Exposure with the PAC lamp tested is more appropriate to the early finishing of composite restorations after placement and curing than with the QTH. However both lamps were capable of producing comparable surface hardness, with appropriate exposure protocols. The effect of increased tip-to-composite distance was generally not significant between the lamps for continuous exposure.

Acrylic Resins↗

Assessing occupational mercury exposures during the on-site processing of spent fluorescent lamps.

On-site processing of spent fluorescent lamps reduces storage space requirements and prevents mercury-containing lamp contents from entering the municipal waste stream, but such processing activities are typically not carried out in facilities specifically designed for the operation. This circumstance is of particular concern because lamp-handling and -crushing operations can release mercury vapors and aerosols that constitute an occupational exposure risk. In the study reported here, sampling for airborne mercury was performed during the processing of fluorescent lamps in an enclosed work area and in an open, outdoor work environment. In both enclosed and open work environments, exposures in excess of the established mercury exposure limit were detected. Simple interventions to prevent this possible unanticipated source of mercury exposure are described.

Conservation of Natural Resources↗

Video equipment recommendations for slit lamp videography.

Current developments in video technology have made videotaping through a slit lamp a useful capability available at a more reasonable cost. The technical basis of equipment needed to select or design an apparatus for slit lamp videography is reviewed. As an overview, the optimum slit lamp video apparatus would have the following criteria; the slit lamp should have zoom optics and rheostat illumination, the beam splitter should be a mirror or 70/30 type, the camera should have maximal light sensitivity (101ux) with reasonable resolution (greater than 300 lines). The recorder should be SP-Umatic or Super VHS for documentation, or consumer VHS for patient education, and the monitor should be a professional 13- or 15-inch monitor.

Humans↗

Zinc and sodium high pressure lamps for curing composite resins.

Polymerisation characteristics of conventional units for curing composite resins are insufficient considering handling feasibilities particularly in the premolar and molar region. There is also hazardous ocular effect of near ultra-violet part of visible spectra. Sodium high pressure lamp technology has been applied to develop a new high pressure zinc lamp, which is for the first time used for curing composite materials. The results of polymerisation measurements show that future improvements over the usual halogen light sources are possible. Zinc lamp was also compared with the high pressure sodium lamp filled with mercury or cadmium.

Cadmium↗

[Usefulness of the phototherapy lamp in treating hyperbilirubinemia in newborn infants].

An efficiency of the treatment of jaundice with the lamp for phototherapy in own modification has been discussed. The lamp was used for the treatment of 82 neonates divided into three groups depending on the type of therapy: group I included 43 neonates treated with phototherapy alone; group II--32 neonates treated with phototherapy combined with blood transfusions, and group III--7 neonates treated with exchange blood transfusions alone. A mean time of irradiation in neonates of group I did not differ significantly from that used in group II (combined therapy) and did not depend on the cause of the jaundice. The number of blood transfusions decreased markedly with the use of phototherapy carried out with the lamp in own modification. This lamp proved highly effective in the treatment of the jaundice of various etiology and is the method of choice in case of life-threaten neonates.

Bilirubin↗

[Analytical comparison of "paraffin" labeled highly toxic lamp oils with paraffinum perliquidum (DAB 10)].

Coloured and odoriferous lamp oils available as household articles repeatedly lead to ingestion intoxications in children in some cases resulting in a bad course. Labels on containers of lamp oils are misleading, e.g. "pure liquid paraffin" or "without noxious substances", causing considerable misconceptions during therapeutic use by treating doctors. Analyses of four arbitrary chosen lamp oils by GC and GC/MS show that the main components (approx. 98%) are the unbranched saturated hydrocarbons n-decane, n-undecane, n-dodecane, n-tridecane, n-tetradecane. Tests according to the German Pharmacopoeia 10th ed. prove also that "paraffin"-labelled products are not at all identical with medical/pharmaceutical paraffinum perliquidum or liquidum. Lamp oils are low viscous and high toxic petroleum distillates and should be labelled "toxic to humans".

Fuel Oils↗

Use of kerosene lamp containing synthetic pyrethroids to repel mosquitoes.

An indigenous and appropriate method of personal protection was developed and tested in rural areas. It consists of an ordinary kerosene lamp made of tin with a regulator to adjust the wick. Different concentrations of esbiothrin, a synthetic pyrethroid, were mixed in kerosene and allowed to burn in living rooms and cattlesheds from dusk to dawn to observe hourly entry of mosquitoes. The tin lamp (100 ml capacity) without chimney provided the most efficient protection from mosquito bites. The protection varied from 84.2 +/- 8.2 to 97.8 +/- 2.8. Maximum protection was observed against An. culicifacies. Esbiothrin kerosene lamp (0.01%) lighted in living room provided 99.7% protection to exposed human baits seated at a distance of 1 m from the lamp. The technique is simple, cost-effective and does not require electricity and can be used both for illumination and repelling mosquitoes in remote and inaccesible areas.

Allethrins↗

The tyrosine-based lysosomal targeting signal in lamp-1 mediates sorting into Golgi-derived clathrin-coated vesicles.

Diversion of membrane proteins from the trans-Golgi network (TGN) or the plasma membrane into the endosomal system occurs via clathrin-coated vesicles (CCVs). These sorting events may require the interaction of cytosolic domain signals with clathrin adaptor proteins (APs) at the TGN (AP-1) or the plasma membrane (AP-2). While tyrosine- and di-leucine-based signals in several proteins mediate endocytosis via cell surface CCVs, segregation into Golgi-derived CCVs has so far only been documented for the mannose 6-phosphate receptors, where it is thought to require a casein kinase II phosphorylation site adjacent to a di-leucine motif. Although recently tyrosine-based signals have also been shown to interact with the mu chain of AP-1 in vitro, it is not clear if these signals also bind intact AP-1 adaptors, nor if they can mediate sorting of proteins into AP-1 CCVs. Here we show that the cytosolic domain of the lysosomal membrane glycoprotein lamp-1 binds AP-1 and AP-2. Furthermore, lamp-1 is present in AP-1-positive vesicles and tubules in the trans-region on the Golgi complex. AP-1 binding as well as localization to AP-1 CCVs require the presence of the functional tyrosine-based lysosomal targeting signal of lamp-1. These results indicate that lamp-1 can exit the TGN in CCVs and that tyrosine signals can mediate these sorting events.

Adaptor Protein Complex alpha Subunits↗

Diagnosis of lysosomal storage disorders: evaluation of lysosome-associated membrane protein LAMP-1 as a diagnostic marker.

Early diagnosis of lysosomal storage disorders (LSDs), before the onset of irreversible pathologies, will be a key factor in the development of effective therapies for many of these disorders. Newborn screening offers a potential mechanism for the early detection of these disorders. From studies of both normal and LSD-affected human skin fibroblasts we identified the lysosome-associated membrane protein LAMP-1 as a potential diagnostic marker. We have developed a sensitive method for the quantification of this protein with a time-resolved fluorescence immunoassay. A soluble form of LAMP-1 was observed in plasma samples, and determination of 152 unaffected individuals gave a median value of 303 micrograms/L with the 5th and 95th percentile at 175 and 448 micrograms/L respectively. Plasma samples from 320 LSD-affected individuals representing 25 different disorders were assayed. We observed that 17 of the 25 disorder groups tested had > 88% of individuals above the 95th percentile of the control population, with 12 groups having 100% above the 95th percentile. Overall, 72% of patients had LAMP-1 concentrations above the 95th percentile of the unpartitioned control population. We suggest that LAMP-1 may be a useful marker in newborn screening for LSDs.

Adolescent↗