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At least 217 records · Page 12Linked to original sources

Congenital hemorrhagic disorders in Jordan.

The results of a three year prospective study of inherited bleeding syndromes in Jordan is presented. There were 112 patients from 64 families. Of these there were 42 patients with hemophilia A, 23 with Glanzmann's thrombasthenia, 22 with von Willebrand's disease, 11 with Christmas disease, 6 with hypofibrinogenemia, 3 with afibrinogenemia, 2 with factor XIII deficiency, 2 with storage pool disease and 1 with factor XI deficiency. The pattern of inherited bleeding syndromes in Jordan is different from that seen in Europe and U.S.A. in that Glanzmann's thrombasthenia is very common. High proportion of hemophiliacs were severe. Arthropathy was common. A significant number of bleeders had fatal hemorrhage. In a high proportion of patients, no family history of bleeding was found.

Adolescent↗

Distribution of adult lactase phenotypes in Bedouins and in urban and agricultural populations of Jordan.

Lactose tolerance tests with breath hydrogen determination identified 39 lactose malabsorbers among 162 Jordanian Bedouins (24%), and 111 lactose malabsorbers among 148 subjects from the urban/agricultural zone of western Jordan and Palestine (75%). This highly significant difference supports the hypothesis that milk dependence in nomadic desert populations resulted in selective pressures in favour of the lactase persistence gene. Within the urban/agricultural zone which extends from the desert border in Jordan to the Mediterranean shore, a significant increase in the frequency of lactose malabsorbers (and hypolactasia gene frequencies) from east to west was observed. The suggested genetic cline is problably due to migration from the desert populations to the agricultural zone.

Adolescent↗

Diphtheria in Jordan: a diminishing yet important paediatric disease.

Twenty-seven cases of diphtheria (15 male, 12 female) admitted over a 2-year period, 1977-1978, at the Jordan University Hospital were reviewed. The majority were admitted during autumn and were in the 2-9-year age group. Eleven patients were not vaccinated and six were questionably vaccinated; of these seven died. In 10 patients who were partially or completely vaccinated, only one died. Antitoxin was given to 23 patients at varying intervals after the onset of the disease. No antitoxin was given to the patients who were admitted after the tenth day of the illness. Fourteen complications developed in 13 patients. One patient died with upper airway obstruction, four died with myocarditis, and three patients died with the respiratory complications of polyneuritis. The case fatality rate was 29%. While in Jordan the incidence rate of diphtheria has been decreasing steadily, limited outbreaks are likely to continue to occur unless a higher immunization rate is achieved.

Adolescent↗

Measles in Jordan: a prototype of the problems with measles in developing countries.

Until recently measles was a very severe illness of infancy and early childhood in Jordan. Incidence rates were estimated to be as high as 500 to 1000/100,000 and case fatality rates were as high as 10%. Since 1981 mandatory and routine vaccination was introduced by the Ministry of Health. Because infants accounted for the most severe cases and almost all mortality, measles vaccine was given at 9 months of age. No booster doses were recommended. Since 1981 there has been a steady shift in the age distribution of cases toward the older age group. In recent years children > 5 years of age accounted for > 60% of cases. Commensurate with that the mortality rate has decreased to almost nil in recent years. There is also evidence of a marked decrease of inpatient admission of measles cases to one of the largest hospitals, the Jordan University Hospital. Despite high immunization rates in excess of 88%, however, outbreaks of measles continue to occur. To evaluate the impact of measles vaccination on outbreaks, a study in one village in 1987 showed that there was almost no protective efficacy in children > 5 years of age (relative risk 0.80 and confidence interval 0.06 to 0.67 vs. relative risk 0.73 and confidence interval 0.54 to 1.15). Although the current measles immunization strategy has decreased the mortality and morbidity rates, we propose that the continuing occurrence of outbreaks necessitates the addition of a booster dose after 15 months of age.(ABSTRACT TRUNCATED AT 250 WORDS)

Age Factors↗

Trends in fertility and family planning in Jordan.

A national fertility sample survey conducted in 1972 on the East Bank of the Hashemite Kingdom of Jordan collected information on fertility levels, desire for additional children, and knowledge and practice of family planning. The data suggest that in Jordan, as in many other developing countries, the fertility rate is extremely high, and that, while rural/urban residence and socio-economic status have no significant influence on fertility, educational attainment of wives does have a marked effect on fertility. The survey results also indicate that, while knowledge of contraception is not lacking, its practice is limited, and that the average ideal family size is lower than the actual size among almost all socioeconomic groups.

Abortion, Legal↗

Prevalence and associated factors of hypertension: results from a three community-based survey, Jordan.

The aim of this study was to estimate the prevalence of hypertension, to determine its association with certain cardiovascular disease risk factors, and to evaluate level of hypertension awareness and control in an adult population in Jordan. The study used a cross-sectional population survey of a systematic sample of three communities. Data for the sample of 2299 adults, aged 25 years and older, were collected from September 1994 to September 1995. A total of 370 subjects or 16.1% were found to have hypertension. The prevalence rate was higher among women (17.1%) than men (14.4%). Logistic regression analysis indicated that hypertension was positively associated with gender, age, family history of hypertension, diabetes mellitus, and total serum cholesterol, but negatively associated with level of education. No association between hypertension and smoking was detected in this study. About one-half (48.6%) of hypertensives in this study were unaware of their diagnosis. Awareness of hypertension was positively associated with age and family history. More than one-third (36.5%) of those aware of their diagnosis did not achieve control of their hypertension. Hypertension appears to be a common public health problem in Jordan. Awareness and control of hypertension are far below optimal levels.

Adult↗

An innovative approach to teaching maternal/infant care in Jordan.

Cultural and religious beliefs in Jordan do not allow male nursing students to practice in the female patients' wards, especially in maternity units. Yet a maternal and infant care nursing course is a required component of Jordan's four-year undergraduate nursing curriculum. Below, how a maternal/infant care course specific for male nursing students with the aim of teaching related but culturally appropriate nursing skills was developed.

Culture↗

The endemicity of Leishmania tropica (zymodeme MON-137) in the Eira-Yarqa area of Salt District, Jordan.

The endemicity of cutaneous leishmaniasis (CL) caused by Leishmania tropica was ascertained in a focus of the disease around Eira and Yarqa in Salt District, Jordan. This focus is about 10 km to the east of another focus of CL, where L. major is the causative agent. As CL occurs sporadically in the study area, with nine cases diagnosed between 1993 and 1995, it is probably zoonotic. Each case had one or two lesions and most lesions were on the face. Isoenzymatic electrophoresis showed that all the parasites isolated in the Eira-Yarqa focus and identified to zymodeme level belonged to zymodeme MON-137 and therefore differed from all the L. tropica isolates identified in other regions of Jordan. Eight species of Phlebotomus (P. alexandri, P. major, P. sergenti, P. papatasi, P. perfiliewi, P. jacusieli, P. canaaniticus and P. arabicus), two members of the Sergentomyia dentata group and S. tiberiadis and S. taizi were collected in the focus, using castor-oil traps. The epidemiological significance of the sandflies collected is discussed.

Adolescent↗

Morphological phylogeny of Geusibia Jordan, 1932 (Siphonaptera: Leptopsyllidae) and the host-parasite relationship with pikas.

Thirteen species of fleas of the genus Geusibia Jordan, 1932 were included in a cladistic analysis based on morphological characters. The results support Geusibia as a monophyletic group within Ctenophyllus Wagner, 1927 (sensu lato) and there are five diagnostic characters that distinguish Geusibia from related genera of Ctenophyllus (s. l). There is no evidence to support a subgeneric classification. We propose that G. ochotona Zhan, Cai & Wu, 1997 and G. lacertosa(Smit, 1975) are junior synonyms of G. torosa Jordan, 1932. After a reconciliation analysis, only two co-speciation events were found in the host-parasite association between Geusibia and pikas (Ochotona:Ochotonidae: Lagomorpha). Therefore, there are no co-evolutionary relationships between them, although a high host preference of Geusibiaspp. is recorded. The distribution and host selection of Geusibia, relative to host associations, are also discussed. Although most specimens of Geusibia are found on pikas, the host is not the definitive factor in the distribution of the genus. Some environmental factors and some host behaviors also determine the presence of Geusibia. Therefore, Geusibia is defined as a host-habitat-dependent flea.

Animals↗

Seroprevalence of and risk factors for Bartonella henselae and Bartonella quintana infections among pet cats in Jordan.

To determine the seroprevalences of Bartonella henselae and Bartonella quintana antibodies in Jordanian pet cats, serum samples from 153 cats from three geographical regions were analyzed. Seroprevalences were determined by indirect immunofluorescence. The true seroprevalences to B. henselae and B. quintana were 32 and 1.5%, respectively. The seroprevalence of B. henselae-specific antibodies in cats from northern Jordan was significantly higher than in cats from the central or southern parts of Jordan. The seroprevalence to B. henselae increased to age 2 years. Odds of seropositivity were higher in cats living outdoors, showing hunting behavior, having a flea infestation and of a mixed breed. No association was detected with sex.

Animals↗

Hydrodynamical effects on spatial distribution of enteric bacteria in the Jordan River-Lake Kinneret contact zone.

The aim of this study was to determine under what hydrodynamic conditions the change in the number of enteric bacteria in the water of the River Jordan--Lake Kinneret contact zone was due to sedimentation and under what conditions the change was due to dilution. The data were then utilized to build a conceptual model explaining the distribution of biological pollutants (bacteria) in the river-lake contact zone of a shallow tropical lake. The study uses, as an example, the microbial communities of the River Jordan--Lake Kinneret contact zone. The changes in numbers of three groups of bacteria (fecal coliforms, Escherichia coli and Klebsiella pneumoniae) along the jet flow agree well with changes in the concentration of suspended particulate matter, caused by the sedimentation of particles.

Animals↗

Exterior letters are not privileged in the early stage of visual word recognition during reading: comment on Jordan, Thomas, Patching and Scott-Brown (2003).

Potential sources for the discrepancy between the letter position effects in T. R. Jordan, S. M. Thomas, G. R. Patching, and K. C. Scott-Brown's (2003; see record 2003-07955-013) and D. Briihl and A. W. Inhoff s (1995; see record 1995-20036-001) studies are examined. The authors conclude that the lack of control over where useful information is acquired during reading in Jordan et al.'s study, rather than differences in the orthographic consistency and the availability of word shape information, account for the discrepant effect pattern in the 2 studies. The processing of a word during reading begins before it is fixated, when beginning letters occupy a particularly favorable parafoveal location that is independent of word length. Knowledge of parafoveal word length cannot be used to selectively process exterior letters during the initial phase of visual word recognition.

Attention↗

Two familial cases of Jordans' anomaly. Ultrastructural studies and the development of fat-containing vacuoles in the neutrophilic series.

A study was conducted on two brothers with Jordans' anomaly. Fat-containing vacuoles were noticed in all leukocytes of the peripheral blood and cells of the myeloid series including myeloblasts, but the serum lipids showed no abnormalities. However, cells of the erythroid series, megakaryocytes and platelets did not contain these vacuoles. An increase in vacuole number was observed as the leukocytes matured. Histochemically, it was suggested that these vacuoles contained neutral fat based on staining with Sudan III and Nile blue sulfate. Ultrastructurally, these vacuoles were unassociated with lysosomes or other cell organelles. Although the etiology of Jordans' anomaly could not be clarified by this study, genetic factors may be involved.

Adult↗

Clinical and inheritance profiles of Kallmann syndrome in Jordan.

BACKGROUND: Proper management of patients with Kallmann syndrome (KS) allows them to attain a normal reproductive health. The purpose of this study is to demonstrate the presentation modalities, phenotypes and the modes of inheritance among 32 patients with Kallmann syndrome in Jordan. Recognition of the syndrome allows for prompt proper management and provision of genetic counselling. SUBJECTS: Over a period of five years (1999-2004), the clinical and inheritance profiles of 26 male and 6 female patients with Kallmann syndrome from 12 families were evaluated at the National Center for Diabetes, Endocrinology and Genetics in Jordan. RESULTS: The patients belonged to twelve Jordanian and Palestinian families and their age at presentation ranged from 4 - 46 years. Nine boys aged 4-14 years presented with cryptorchidism and microphallus, all other males presented with delayed puberty, hypogonadism and/or infertility. The main presentation among six female patients was primary amenorrhea. Intrafamilial variability in clinical phenotype was specifically evident for renal abnormalities and sensorineural hearing impairment. Familial KS was diagnosed in 27 patients belonging to five families with the X-linked mode of inheritance and two families with the autosomal recessive mode of inheritance. CONCLUSIONS: (1) the majority of cases in this study represented the X-linked form of KS, which might point to a high prevalence of Kal 1 gene in the population. (2) Genetic counselling helps these families to reach a diagnosis at an early age and to decide about their reproductive options. (3) Children presenting with cryptorchidism and microphallus in our population should be investigated for KS.

Journal Article↗

Vasospastic angina in patients with systemic triglyceride storage disease with Jordans' anomaly and cardiomyopathy.

Vasospastic angina was demonstrated clinically and angiographically in a 54-year-old patient with systemic triglyceride storage disease and cardiomyopathy. He and his younger sister had been diagnosed in 1985 as having systemic triglyceride storage with Jordans' anomaly. In 1993, he began complaining of rest and effort chest pain in the morning, which was accompanied by ST depression by ECG. Sublingual nitroglycerine was effective for treating this pain. Intracoronary injection of acetylcholine induced severe coronary vasoconstriction in the left anterior descending artery. Left ventricular contraction was diffusely impaired. Deposits of numerous triglyceride droplets and a decrease in the density of myofibrils in cardiocytes were found in the specimens obtained by endomyocardial biopsy. The impaired left ventricular contraction may have been due to the changes in myocardial cells. His sister complained of a similar chest pain that was completely controlled by calcium channel antagonis. Thus, our cases demonstrated vasospastic angina associated with cardiomyopathy secondary to systemic triglyceride storage disease with Jordans' anomaly, though the causal relationship between these conditions remains unclear.

Adult↗

Differences in self-reported oral health behavior between dental students and dental technology/dental hygiene students in Jordan.

The aim of this study was to compare differences in oral health behavior between dental students and dental technology/dental hygiene students in Jordan. One hundred and five dental students and seventy-eight dental technology/dental hygiene students were recruited into this study. All subjects were recruited from the students who were receiving training at the clinics and laboratories that belong to the Faculty of Dentistry, Jordan University of Science and Technology. The Hiroshima University-Dental Behavioral Inventory (HU-DBI) was used to assess the oral heath behavior of the subjects. Significant differences were found between students from different disciplines. Dental students were found to worry more about visiting their dentist, to be less aware of bleeding gums when brushing and were less bothered by the color of their gums compared with dental technology and dental hygiene (DT/DH) students (P < 0.05, P < 0.001 and P < 0.05, respectively). Dental students tended to be more professionally educated about brushing and to have a belief that they cannot clean their teeth well without using toothpaste (P < 0.01 and P < 0.001, respectively). Most of them did not feel they have brushed well unless they brush with strong strokes (P < 0.05). A logistic regression model showed that it might be possible to distinguish dental students from DT/DH students by using three items of the HU-DBI and the level of dental education. The difference in the HU-DBI scores was not a major feature. There were significant differences in oral health attitudes/behavior between dental students and DT/DH students. The findings might reflect differences in students' training experience and education between different specialties.

Attitude to Health↗

Short-term clinical study comparing supragingival plaque removal and gingival bleeding reduction of the Philips Jordan HP735 to a manual toothbrush in periodontal patients in a maintenance program.

The Philips Jordan HP735 was compared to a manual brush for plaque removal efficacy and reduction of gingival bleeding. Subjects in a periodontal maintenance program were randomly divided into two groups; Group I (n = 27), average age 36.9 years, brushed with the manual brush; and Group II (n = 22), average age 32.9 years, brushed with the Philips Jordan HP735 electric brush. A dichotomous plaque and bleeding index was used at six sites on all teeth at baseline, three, six and nine weeks. The subjects did not use any other cleaning devices during the study. No significant statistical difference in plaque score or bleeding score was found between the two groups at baseline. Plaque scores did not statistically significantly decrease over time in either group, and there was no significant difference in plaque removal between groups during the study. The bleeding index decreased significantly in the electric toothbrushing group; however, due to the large variation in bleeding scores between subjects, the difference in the number of bleeding sites was not statistically significant between the two groups. In conclusion, in a group of periodontal patients in a maintenance phase, using an electric toothbrush did not significantly enhance plaque removal, but did decrease bleeding compared to baseline. The difference in bleeding percentages was not statistically significant compared to a manual brush.

Adolescent↗

Jordan M. Phillips, M.D.--postdoctoral educator at large.

Twenty years ago Jordan Phillips recognized the importance of laparoscopy and aroused the interest of gynecologists by founding the American Association of Gynecologic Laparoscopists (AAGL). Within five years he had expanded the teaching mission of the AAGL to microsurgery, which revolutionized infertility surgery. Through his insatiable personal drive, he catalyzed the movement of people and ideas on an international level by organizing numerous postgraduate courses in North America, Europe and Asia, and later Australia and South America. Through his untiring efforts as an educator, Jordan Phillips has played a major role in preparing gynecologists in many parts of the world for the commanding position of advanced laparoscopic surgery, hysteroscopy and microsurgery in gynecologic practice.

Gynecology↗