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[Influential clinical and pathological factors on prognosis of renal cell carcinoma].

The clinical, pathological and survival data were analyzed for 42 patients with nephrectomy for renal cell carcinoma, who visited our department between 1987 and 1992. The factors influencing prognosis were evaluated. There were 33 males and 9 females with an average age of 59.1 years old. Forty-five percent (19 patients) of the cases were detected incidentally. These incidental cases showed a higher survival rate than the cases with symptoms although the difference was not statistically significant. Positive acute phase reactant, clinical stage, grade and type of infiltration were to be considerably predictive factors indicating poor prognosis. Embolization of renal artery for neo -adjuvant therapy could not improve the survival rate. Interferon-alpha for adjuvant therapy did not prolong the survival team clearly.

Acute-Phase Proteins↗

[Outcome of HCV infection in intravenous drug addicts and influential factors].

A total of 154 intravenous drug addicts with antibody to hepatitis C virus (Anti-HCV) were followed up for 6 and 15 months, respectively. The corresponding negative conversion rates of anti-HCV were 11.0% (17/154) and 33.3% (29/87), respectively. The data were analysed by logistic curve fitting. Results showed that marriage and income status have significant influence on negative conversion rate of anti-HCV.

Adult↗

[A cohort study on the difference of stroke incidence between urban and rural populations and related influential factors].

A longitudinal prospective study was carried out in a cohort of 1 809 persons aged 35 to 74 at entry, including 778 subjects from urban and 1 031 from rural areas. The average annual age-adjusted incidence of stroke was 95.7/10(4) in urban group during a 15-year-period from 1979 to 1994, which was significantly lower than that in rural areas (183.1/10(4) during a 11-year-period from 1983 to 1994. According to the results through multivariate regression analysis and comparative study of risk factors between urban and rural group at baseline examination, it was suggested that in addition to age, factors as drinking habit, smoking, ECG abnormality and elevated systolic blood pressure (in female) were important parameters causing the difference of incidence between urban and rural groups. Other than those factors mentioned above, low level of serum cholesterol in rural population was also suspected as a possible factor positively influencing the development of stroke.

Adult↗