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At least 217 records · Page 12Linked to original sources
PubMed2002

[Dilzem-retard efficiency in patients with ischemic heart disease and heart failure].

Effectiveness of a prolonged form of diltiazem was studied in 20 patients with stable effort angina and chronic cardiac failure (NYHA functional class II). Dilcem-retard was given in a dose 180 mg/day for 6 months. Clinical condition, exercise tolerance, left ventricular functional and geometric parameters, heart rhythm variability, late potentials, Holter monitoring evidence were assessed before and after the treatment. Dilcem-retard improved the patients' condition, exercise tolerance, promoted normalization of left ventricular diastolic function, had no negative influence on cardiac output, reduced occurrence of sympathicotonia and late potentials.

Aged↗
PubMed2003

[Circadian rhythms in cardiovascular diseases--ischemic heart disease].

Several key advances in understanding of pathophysiology now provide the opportunity to develop improved treatment and prevention strategies. First, the importance o mechanism of plaque rupture and thrombosis in onset of myocardial infarction. Second, there has been demonstrated, that plaques that lead to acute occlusion often have only a mild degree of stenosis. A third advance that has stimulated the field has been the recognition that time of onset of cardiac events is not random but instead shows a circadian pattern of onset. In the decade since the 1985 observation by Muller a spol. that the frequency of onset of myocardial infarction peaks at 9 a.m., numerous publications have supported this observation not only for myocardial infarction, but also for sudden cardiac death, transient myocardial ischemia, and stroke. Refinement of these epidemiological observations has led, first, to the conclusion that the morning peak in disease onset is due in part to the physical and mental stressors associated with morning awakening and activity and, second, that stressors such as heavy physical activity and anger can trigger acute cardiovascular events.

Circadian Rhythm↗
PubMed2001

[Krakow Program for Secondary Prevention of Ischaemic Heart Disease. Part III. Secondary prevention of ischaemic heart disease after discharge].

UNLABELLED: Even though the majority of actions undertaken within the secondary prevention of ischaemic heart disease should be initiated while the patient is still hospitalized, the maximum benefit (measured as decreased cardiovascular risk) achieved depends mostly on the continuation and modification of these actions in the postdischarge period. There is not much known about the quality of medical care provided for patients after hospitalization due to ischaemic heart disease. The aim of the study was to assess the quality of postdischarge care in the field of secondary prevention of ischaemic heart disease. METHODS: Consecutive patients (age > or = 70 years; residing in the Cracow province) were identified according to the following clinical diagnoses or procedures: acute myocardial infarction, unstable angina, CABG and PCI. Out of 536 patients 418 took part in the control visit 6-18 months after discharge. Risk factors and medication used were assessed. RESULTS: High total cholesterol (> or = 5.2 mmol/l) was found in 65.8% of patients, high blood pressure (> or = 140/90 mmHg) in 46.2%, obesity (BMI > or = 30 kg/m2) in 24.6%, fasting glucose over 6.0 mmol/l in 17.7% and smoking in 16.3%. The frequency of antiplatelet drugs and beta-blockers use decreased whereas that of lipid-lowering drugs increased in the postdischarge period. The highest frequency of use of antiplatelets and lipid-lowering drugs, as well as the best control of hypercholesterolemia was found in the PCI group, whereas the lowest frequency of smoking was found in the CABG group. CONCLUSIONS: Insufficient control of risk factors and the frequency of secondary prevention using drugs was found. There is a need to intensify secondary prevention in patients with ischaemic heart disease in the postdischarge period.

Adrenergic beta-Antagonists↗