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A biochemical study of two bifunctional reagents as alternatives to formocresol.

Two bifunctional reagents, glutaraldehyde and dimethylsuberimidate, were compared to formaldehyde with respect to fixation and modification of protein. Glutaraldehyde proved the superior fixative based on cross-linking and enzyme degradation assays. An immunoprecipitation assay suggests that the reaction products of glutaraldehyde may have altered antigenicity.

Aldehydes↗

[Discussion of the treatment of Formocresol (FC-ZOE) and Glutaradehyde (GA-ZOE) for pulpitis and periapical disease on primary teeth]

This study was discussed of the treatment of FC-ZOE and GA-ZOE for pulpitis and periapical disease on primary teeth.The post-operation observation was from 18 to 24 months.The result demostrated that the treatment for pulpitis is good,but for periapical disease is not satisfying. Ga-ZOE is effective as a fixing agent of devitalization for gangrenous root canal,and it was ineffective as an aseptic agent for infective root canal.FC-ZOE was disadvantage as a filling agent of root canal.

Journal Article↗

Pulpotomy medicaments for vital primary teeth. Surveys to determine use and attitudes in pediatric dental practice and in dental schools throughout the world.

Surveys were sent to all Canadian pediatric dental specialists and to Heads of Departments of Pediatric Dentistry of selected dental schools throughout the world, in order to determine the use of and attitudes toward pulpal techniques on vital primary teeth. The preferred pulpotomy medicament of Canadian pediatric dental specialists was the 1:5 formocresol dilution, which was used by 50 percent of the respondents. The second most prevalent medicament was full-strength formocresol, used by 42.2 percent of respondents. The most prevalent medicament utilized in pediatric dental departments of dental schools was full-strength formocresol (40.8 percent) followed in popularity by the 1:5 formocresol dilution (36 percent). Scandinavia was the only geographic region to deviate from formocresol as the preferred pulpotomy medicament. Seventy percent (70 percent) of the pediatric dental departments in Scandinavia preferred calcium hydroxide for pulpotomies. Although 50 percent of the pediatric dental specialists and 55.2 percent of pediatric dental departments expressed concern about harmful effects of the preferred pulpotomy medicament, only 21.2 percent of the dentists and 29.6 percent of the schools were contemplating a change to another material. Because of its long history and lasting popularity, formocresol has been the most widely studied of the many pulpotomy medicaments. Although other techniques have been proposed and studied, the vast majority of pediatric dental practitioners in Canada (92.4 percent) and dental schools worldwide (76.8 percent) utilize either the full-strength or the 1:5 dilution of formocresol as the preferred pulpotomy medicament for vital primary teeth.(ABSTRACT TRUNCATED AT 250 WORDS)

Attitude of Health Personnel↗

Outcome of formocresol/ZOE sub-base pulpotomies utilizing alternative radiographic success criteria.

PURPOSE: The purposes of this investigation were to 1) measure success of a primary tooth pulpotomy technique that applies formocresol in the sub-base without the common five-minute application of a formocresol impregnated cotton pellet; and 2) compare success rates of the pulpotomy procedure using traditional criteria found throughout the literature with new criteria recently established, excluding internal resorption as a radiographic failure. METHODS: Clinical and radiographic data were collected from a retrospective chart review of patients receiving formocresol pulpotomies with the application of formocresol in the zinc oxide-eugenol sub-base. RESULTS: Clinical and radiographic data were available for 196 primary molars in 122 children (followup=six to 103 months; mean=49 months). Traditional assessment of radiographic success and failure yielded a success rate of 79%. Alternative assessment excluding internal resorption as a failure yielded a 99% success rate. Most frequently observed pulpal responses were calcific metamorphosis and internal resorption. Overall clinical success was 99%. Two of the 196 teeth were extracted due to failure. A survival analysis demonstrated that the overall probability of survival remained high over time with a cumulative survival of over 95% after six years. CONCLUSIONS: The overall success rates in this study indicate that the formocresol pulpotomy technique incorporating formocresol in the zinc oxide-eugenol sub-base is a very successful treatment modality for primary molars requiring pulp therapy.

Chi-Square Distribution↗