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At least 217 records · Page 12Linked to original sources
PubMed1975

Clinical studies on diabetes mellitus and diseases of the oral region.

Of the 25,672 patients who visited this clinic between January 1964 and March 1973, 126 were diabetic. These were examined statistically and the following results were obtained. 1. Together with diabetes the following disorders pertaining to the realm of oral surgery were observed: Alveolar pyorrhea (49 cases), infection of oral tissues other than periodontal tissues (24 cases), simple periodontitis (15 cases), tumors (13 cases), dental caries (9 cases), neuralgia (6 cases) and several disorders. 2. Of these 126 cases, 85 needed tooth extraction, which was actually performed in 67 cases with the following results: (a) Of the 67 cases, 13 developed complications such as dry socket, postoperative infection, sequestrum around the extraction socket, etc. This was a significantly higher incidence than in an equal number of controls. (b) In the cases with complications convalescence was prolonged to an average of 54.2 days. (c) In the cases with complications, the preoperative fasting blood sugar level averaged 194.5 mg/dl, which was much higher than in the cases which did not develop complications (average 142.4 mg/dl).

Diabetes Complications↗
PubMed2007

Iatrogenic mandibular fracture associated with third molar removal. Can it be prevented?

Removal of third molars is the most common procedure in oral surgery. It may be associated with complications, such as sensory damage , dry socket, infection and iatrogenic damage. A case of mandibular angle fracture during third molar extraction in a 37-year-old female is reported. Literature review on the possible etiologies and ways of prevention were recorded. The reason is believed to be multifactorial and include: age, gender, degree of impaction, relative volume of the tooth in the jaw, preexisting infection or bone lesions, failure to maintain a soft diet in the early postoperative period and the surgical technique. It is possible to reduce the risk of this complication by adoption of preventive measures.

Adult↗
PubMedDate not supplied

[Incidence of impacted wisdom teeth and complication in Thai community].

A prospective study of mandibular third molar wisdom teeth including the type, age groups, presurgical and post surgical problem of the 175 Thai patients (184 teeth) was analysed. The patients were male 54.86% female 45.17%. The youngest patient was 16 years old and the oldest patient was 56 years old. The age group 16-24 years was found largest (48.57%). The mesioangular impaction was found 62.5%, vertical impaction 18.47, horizontal impaction 17.39% disto-angular impaction 1.09%, buccolingual impaction 0.54% respectively. The presurgical symptoms were pain, headache, joint pain, mastoid pain, infection, food impaction and orthodontic need. The postsurgical complication rate overall 6.86% that include dry socket 2.86%, bleeding 2.29% and infection 1.14%, dysesthesia 0.57%.

Adolescent↗
PubMed1998

Evaluation of buccoadhesive metronidazole tablets: microbiological response.

Metronidazole has been found beneficial in a number of oro-dental infections namely dry socket, gingivitis, smelling tumours and periodontal diseases where anaerobes are implicated as pathogens. Buccoadhesive tablets of metronidazole were prepared by compressing the drug, bioadhesive polymers namely Carbopol-934P, a cellulose ether derivative, mannitol and suitable flavouring and sweetening agents. The tablet showed good release in vitro. It was subjected to in-situ release studies using bovine cheek pouch membrane in a flow through cell. The concentration was found to be above the MIC of the drug over the entire period of the release studies. The samples were tested against anaerobic strains commonly found in oro-dental infections. Since anaerobes are very slow growing microorganisms, a method for testing their susceptibility to metronidazole solutions was developed which can be used for other bioadhesive formulations which are active against anaerobes.

Adhesives↗
PubMed1975

The effect of sulfonamides on pain and swelling following removal of ectopic third molars.

A double-blind, placebo-controlled trial was carried out to study the value of cones containing sulfanilamide and sulfathiazole in the healing of third molar sockets. On the seventh postoperative day, 94 patients were examined regarding pain, swelling and the overall effect of the operation. Trials were run to compare sulfa cones directly with a placebo: in addition, the placebo and sulfa drugs were each compared with the effects of no medication. Pairs were made of the left and right mandibular third molars in the same patient and the results assessed by sequential analysis. It was found that although sulfa cones were better than the placebo, they themselves were no better or worse than leaving the socket alone.

Clinical Trials as Topic↗
PubMed1996

Histologic evaluation of human extraction sockets treated with demineralized freeze-dried bone allograft (DFDBA) and cell occlusive membrane.

This study evaluated new bone formation in human extraction sockets treated with demineralized freeze-dried bone allografts (DFDBA) and celloc occlusive membranes. Hard tissue biopsies of 7 sites in 6 patients were obtained 14 weeks to 13 months following extraction and grafting. Histologic analysis revealed that individual particles of DFDBA were discernible up to 13 months in situ. In all samples, all particles of DFDBA were well incorporated within new bone, which exhibited osteocyte-containing lacunae. Distinct cement lines clearly demarcated the DFDBA particles from the surrounding, intimately-apposed woven and lamellar bone. The marrow demonstrated a mild degree of fibrosis without signs of inflammatory reaction. There was also a notable lack of fibrous encapsulation of the allograft, and little osteoclasis was observed. Our findings demonstrate that commercially available DFDBA has the potential to function physically as a nidus for appositional new bone growth in alveolar sockets following tooth extraction. Further investigations of the biological activity of DFDBA in situ are warranted.

Adult↗
PubMed1978

Antifibrinolytic prevention of alveolitis sicca dolorosa.

In a double-blind study dental cones containing the antifibrinolytically active propylic ester of p-hydroxybenzoic acid (PEPH), sulfanilamide and sulfathiazol or placebo were placed in dental sockets following removal of impacted mandibular third molars on 95 consecutive patients, 50 women and 45 men. The duration of the operation, the type of surgeon, preoperative symptoms and the use of peroral anticonception were recorded. The patients were asked to return to the clinic on the seventh postoperative day, and it was then noted whether the healing was disturbed by Alveolitis Sicca Dolorosa (ASD) or not. Statistical analysis showed a significantly prophylactic effect of PEPH against ASD. The prophylactic effect was most pronounced in the group of male patients without preoperative symptoms and in the group of patients operated by dental students. It could not be demonstrated that the sulfa drugs in the cones were of any benefit to the healing of the socket.

Adolescent↗
PubMed1996

Healing of tooth extraction sockets in experimental diabetes mellitus.

PURPOSE: This study was undertaken to examine the healing of molar tooth extraction sockets in the streptozotocin-treated, diabetic rat. MATERIALS AND METHODS: Insulin-dependent diabetes mellitus was induced in a group of mature Sprague-Dawley rats by injecting streptozotocin. Control animals were injected with citrate buffer only. A third group of rats were also injected with streptozotocin, but the diabetes was controlled by daily injections of insulin. After 2 weeks, all of the rats underwent extraction of the right maxillary molar teeth under general anesthesia. The rats were killed at varying intervals and the maxilla and calvaria recovered in continuity. Tissue sections were stained with hematoxylin-eosin and periodic acid-Schiff (PAS), the latter to identify diabetic microangiopathy. RESULTS: At 10 days after tooth extraction in the control and insulin-streptozotocin-treated rats, thick collagen fibers formed a pretrabecular scaffold that dictated the direction of the forming trabeculae. The collagen fibers in the diabetic socket were thin and scanty, and formed a narrow layer in the apical part. There was no evidence of diabetic microangiopathy in the extraction sockets of diabetic, insulin-treated diabetic, or normal rats. CONCLUSION: These histologic observations suggest that in uncontrolled, insulin-dependent diabetes, the formation of the collagenous framework in the tooth extraction socket is inhibited, resulting in delayed healing and increased alveolar destruction.

Alveolar Bone Loss↗